{"id":"https://openalex.org/W7225645917","doi":"https://doi.org/10.3390/diagnostics16213697","title":"Ultra-High-Resolution Imaging of Rectal Cancer with Photon-Counting Detector Computed Tomography: An Exploratory Pilot Study on the Impact of Slice Thickness and Monoenergetic Reconstruction Level on Image Quality","display_name":"Ultra-High-Resolution Imaging of Rectal Cancer with Photon-Counting Detector Computed Tomography: An Exploratory Pilot Study on the Impact of Slice Thickness and Monoenergetic Reconstruction Level on Image Quality","publication_year":2026,"publication_date":"2026-11-09","ids":{"openalex":"https://openalex.org/W7225645917","doi":"https://doi.org/10.3390/diagnostics16213697"},"language":"en","primary_location":{"id":"doi:10.3390/diagnostics16213697","doi":"https://doi.org/10.3390/diagnostics16213697","is_oa":true,"landing_page_url":"https://doi.org/10.3390/diagnostics16213697","pdf_url":null,"source":{"id":"https://openalex.org/S4210172076","display_name":"Diagnostics","issn_l":"2075-4418","issn":["2075-4418"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diagnostics","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.3390/diagnostics16213697","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113559656","display_name":"Andrea Herold","orcid":"https://orcid.org/0000-0002-9324-9889","observed_orcids":["https://orcid.org/0000-0002-9324-9889"]},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Alexander Herold","raw_affiliation_strings":["Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Waehringer Guertel 18\u201320, 1090 Vienna, Austria"],"raw_orcid":"https://orcid.org/0000-0002-9324-9889","affiliations":[{"raw_affiliation_string":"Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Waehringer Guertel 18\u201320, 1090 Vienna, Austria","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041720822","display_name":"Andreas Strassl","orcid":"https://orcid.org/0000-0002-7320-0279","observed_orcids":["https://orcid.org/0000-0002-7320-0279"]},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Andreas Strassl","raw_affiliation_strings":["Christian Doppler Laboratory for Machine Learning Driven Precision Medicine, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Waehringer Guertel 18\u201320, 1090 Vienna, Austria","Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Waehringer Guertel 18\u201320, 1090 Vienna, Austria"],"raw_orcid":"https://orcid.org/0000-0002-7320-0279","affiliations":[{"raw_affiliation_string":"Christian Doppler Laboratory for Machine Learning Driven Precision Medicine, Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Waehringer Guertel 18\u201320, 1090 Vienna, Austria","institution_ids":["https://openalex.org/I76134821"]},{"raw_affiliation_string":"Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Waehringer Guertel 18\u201320, 1090 Vienna, Austria","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5135908641","display_name":"Daniela Beitzke","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Daniela Beitzke","raw_affiliation_strings":["Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Waehringer Guertel 18\u201320, 1090 Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Waehringer Guertel 18\u201320, 1090 Vienna, Austria","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109768892","display_name":"Philipp D. Stelzer","orcid":"https://orcid.org/0000-0001-7879-0346","observed_orcids":["https://orcid.org/0000-0001-7879-0346"]},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Philipp Stelzer","raw_affiliation_strings":["Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Waehringer Guertel 18\u201320, 1090 Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Waehringer Guertel 18\u201320, 1090 Vienna, Austria","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066642446","display_name":"Christian Wassipaul","orcid":"https://orcid.org/0000-0002-6468-5577","observed_orcids":["https://orcid.org/0000-0002-6468-5577"]},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Christian Wassipaul","raw_affiliation_strings":["Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Waehringer Guertel 18\u201320, 1090 Vienna, Austria"],"raw_orcid":"https://orcid.org/0000-0002-6468-5577","affiliations":[{"raw_affiliation_string":"Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Waehringer Guertel 18\u201320, 1090 Vienna, Austria","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161324912","display_name":"Theresa Dachs","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Theresa Dachs","raw_affiliation_strings":["Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Waehringer Guertel 18\u201320, 1090 Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Waehringer Guertel 18\u201320, 1090 Vienna, Austria","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161313193","display_name":"Bence Nemeth","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Bence Nemeth","raw_affiliation_strings":["Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Waehringer Guertel 18\u201320, 1090 Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Waehringer Guertel 18\u201320, 1090 Vienna, Austria","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016669461","display_name":"Florian Lindenlaub","orcid":"https://orcid.org/0000-0002-0232-1639","observed_orcids":["https://orcid.org/0000-0002-0232-1639"]},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Florian Lindenlaub","raw_affiliation_strings":["Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Waehringer Guertel 18\u201320, 1090 Vienna, Austria"],"raw_orcid":"https://orcid.org/0000-0002-0232-1639","affiliations":[{"raw_affiliation_string":"Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Waehringer Guertel 18\u201320, 1090 Vienna, Austria","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062078348","display_name":"Ahmed Ba\u2010Ssalamah","orcid":"https://orcid.org/0000-0002-3527-404X","observed_orcids":["https://orcid.org/0000-0002-3527-404X"]},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Ahmed Ba-Ssalamah","raw_affiliation_strings":["Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Waehringer Guertel 18\u201320, 1090 Vienna, Austria"],"raw_orcid":"https://orcid.org/0000-0002-3527-404X","affiliations":[{"raw_affiliation_string":"Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Waehringer Guertel 18\u201320, 1090 Vienna, Austria","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000737388","display_name":"Johannes Laengle","orcid":"https://orcid.org/0000-0003-4771-1398","observed_orcids":["https://orcid.org/0000-0003-4771-1398"]},"institutions":[{"id":"https://openalex.org/I4210092129","display_name":"Comprehensive Cancer Center Vienna","ror":"https://ror.org/00df3z122","country_code":"AT","type":"healthcare","lineage":["https://openalex.org/I2802328216","https://openalex.org/I4210092129"]},{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Johannes Laengle","raw_affiliation_strings":["Division of Visceral Surgery, Department of General Surgery, Comprehensive Cancer Center Vienna, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria"],"raw_orcid":"https://orcid.org/0000-0003-4771-1398","affiliations":[{"raw_affiliation_string":"Division of Visceral Surgery, Department of General Surgery, Comprehensive Cancer Center Vienna, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria","institution_ids":["https://openalex.org/I4210092129","https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044559524","display_name":"Michael M. Bergmann","orcid":"https://orcid.org/0000-0001-8529-1166","observed_orcids":["https://orcid.org/0000-0001-8529-1166","https://orcid.org/0000-0002-3162-4962"]},"institutions":[{"id":"https://openalex.org/I4210092129","display_name":"Comprehensive Cancer Center Vienna","ror":"https://ror.org/00df3z122","country_code":"AT","type":"healthcare","lineage":["https://openalex.org/I2802328216","https://openalex.org/I4210092129"]},{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Michael Bergmann","raw_affiliation_strings":["Division of Visceral Surgery, Department of General Surgery, Comprehensive Cancer Center Vienna, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria"],"raw_orcid":"https://orcid.org/0000-0001-8529-1166","affiliations":[{"raw_affiliation_string":"Division of Visceral Surgery, Department of General Surgery, Comprehensive Cancer Center Vienna, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria","institution_ids":["https://openalex.org/I4210092129","https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034247784","display_name":"Michael Weber","orcid":"https://orcid.org/0000-0002-8507-2219","observed_orcids":["https://orcid.org/0000-0002-8507-2219"]},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Michael Weber","raw_affiliation_strings":["Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Waehringer Guertel 18\u201320, 1090 Vienna, Austria"],"raw_orcid":"https://orcid.org/0000-0002-8507-2219","affiliations":[{"raw_affiliation_string":"Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Waehringer Guertel 18\u201320, 1090 Vienna, Austria","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036309711","display_name":"Dietmar Tamandl","orcid":"https://orcid.org/0000-0003-1996-0688","observed_orcids":["https://orcid.org/0000-0003-1996-0688"]},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":true,"raw_author_name":"Dietmar Tamandl","raw_affiliation_strings":["Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Waehringer Guertel 18\u201320, 1090 Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Waehringer Guertel 18\u201320, 1090 Vienna, Austria","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5053525786","display_name":"Michael A. Arnoldner","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Michael A. Arnoldner","raw_affiliation_strings":["Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Waehringer Guertel 18\u201320, 1090 Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Imaging and Image-Guided Therapy, Medical University of Vienna, Waehringer Guertel 18\u201320, 1090 Vienna, Austria","institution_ids":["https://openalex.org/I76134821"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5036309711"],"corresponding_institution_ids":["https://openalex.org/I76134821"],"apc_list":{"value":2600,"currency":"CHF","value_usd":3137},"apc_paid":{"value":2600,"currency":"CHF","value_usd":3137},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"16","issue":"21","first_page":"3697","last_page":"3697"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12386","display_name":"Advanced X-ray and CT Imaging","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12386","display_name":"Advanced X-ray and CT Imaging","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.003100000089034438,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10844","display_name":"Radiation Dose and Imaging","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rectal-cancer","display_name":"rectal cancer","score":0.9079999923706055},{"id":"https://openalex.org/keywords/photon-counting-ct","display_name":"photon-counting CT","score":0.8880000114440918},{"id":"https://openalex.org/keywords/ultra-high-resolution-ct","display_name":"ultra-high-resolution CT","score":0.8880000114440918},{"id":"https://openalex.org/keywords/slice-thickness","display_name":"slice thickness","score":0.8519999980926514},{"id":"https://openalex.org/keywords/image-quality","display_name":"image quality","score":0.9330000281333923},{"id":"https://openalex.org/keywords/signal-to-noise-ratio","display_name":"signal-to-noise ratio","score":0.8190000057220459},{"id":"https://openalex.org/keywords/contrast-to-noise-ratio","display_name":"contrast-to-noise ratio","score":0.9990000128746033},{"id":"https://openalex.org/keywords/lesion-conspicuity","display_name":"lesion conspicuity","score":0.9879999756813049},{"id":"https://openalex.org/keywords/portal-venous-phase","display_name":"portal venous phase","score":0.7300000190734863},{"id":"https://openalex.org/keywords/pre-treatment-imaging","display_name":"pre-treatment imaging","score":0.6700000166893005},{"id":"https://openalex.org/keywords/image-noise","display_name":"image noise","score":0.35100001096725464},{"id":"https://openalex.org/keywords/radiation-dose-reduction","display_name":"radiation dose reduction","score":0.4359999895095825}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7439000010490417},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.6306999921798706},{"id":"https://openalex.org/C55020928","wikidata":"https://www.wikidata.org/wiki/Q3813865","display_name":"Image quality","level":3,"score":0.5629000067710876},{"id":"https://openalex.org/C35772409","wikidata":"https://www.wikidata.org/wiki/Q1323086","display_name":"Image noise","level":3,"score":0.4812000095844269},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.35100001096725464},{"id":"https://openalex.org/C99498987","wikidata":"https://www.wikidata.org/wiki/Q2210247","display_name":"Noise (video)","level":3,"score":0.3508000075817108},{"id":"https://openalex.org/C141379421","wikidata":"https://www.wikidata.org/wiki/Q6094427","display_name":"Iterative reconstruction","level":2,"score":0.33059999346733093},{"id":"https://openalex.org/C2984485829","wikidata":"https://www.wikidata.org/wiki/Q100766421","display_name":"Noise level","level":3,"score":0.33000001311302185},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.31349998712539673},{"id":"https://openalex.org/C2781156865","wikidata":"https://www.wikidata.org/wiki/Q827023","display_name":"Lesion","level":2,"score":0.3068999946117401},{"id":"https://openalex.org/C2781074409","wikidata":"https://www.wikidata.org/wiki/Q158716","display_name":"Rectum","level":2,"score":0.3001999855041504},{"id":"https://openalex.org/C13944312","wikidata":"https://www.wikidata.org/wiki/Q7512748","display_name":"Signal-to-noise ratio (imaging)","level":2,"score":0.2775999903678894},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.2676999866962433}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.3390/diagnostics16213697","doi":"https://doi.org/10.3390/diagnostics16213697","is_oa":true,"landing_page_url":"https://doi.org/10.3390/diagnostics16213697","pdf_url":null,"source":{"id":"https://openalex.org/S4210172076","display_name":"Diagnostics","issn_l":"2075-4418","issn":["2075-4418"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diagnostics","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.3390/diagnostics16213697","doi":"https://doi.org/10.3390/diagnostics16213697","is_oa":true,"landing_page_url":"https://doi.org/10.3390/diagnostics16213697","pdf_url":null,"source":{"id":"https://openalex.org/S4210172076","display_name":"Diagnostics","issn_l":"2075-4418","issn":["2075-4418"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diagnostics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320327217","display_name":"Siemens Healthineers","ror":"https://ror.org/0449c4c15"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W1996290308","https://openalex.org/W2554936577","https://openalex.org/W2943602527","https://openalex.org/W3110147920","https://openalex.org/W4200039099","https://openalex.org/W4387357794","https://openalex.org/W4390730529","https://openalex.org/W4392817377","https://openalex.org/W4392899897","https://openalex.org/W4401640776","https://openalex.org/W4403400760","https://openalex.org/W4403761385","https://openalex.org/W4408396203","https://openalex.org/W4411671805","https://openalex.org/W4411872942","https://openalex.org/W4416355826","https://openalex.org/W7126081728"],"related_works":["https://openalex.org/W4387643585","https://openalex.org/W4401354465","https://openalex.org/W4402279531","https://openalex.org/W4388973846","https://openalex.org/W4412823945","https://openalex.org/W4392715226","https://openalex.org/W4391655998","https://openalex.org/W4310937763","https://openalex.org/W4404604549","https://openalex.org/W4385645185"],"abstract_inverted_index":{"Background/Objectives:":[0],"To":[1],"evaluate,":[2],"in":[3,30,145,249,282,320,349],"an":[4],"exploratory":[5],"pilot":[6,37],"study,":[7],"the":[8,68,118,132,138,141,273,280,346],"influence":[9,315],"of":[10,23,135,368],"slice":[11,170,222],"thickness":[12,223,310],"and":[13,19,51,92,113,148,194,228,275,294,311,351,354],"monoenergetic":[14],"(ME)":[15],"level":[16,172,212,313],"on":[17],"quantitative":[18],"qualitative":[20,216],"image":[21,105,318],"quality":[22,227,245,319],"ultra-high-resolution":[24],"(UHR)":[25],"photon-counting":[26],"detector":[27],"CT":[28],"(PCD-CT)":[29],"rectal":[31],"cancer":[32],"(RC).":[33],"Methods:":[34],"This":[35],"prospective":[36],"study":[38],"enrolled":[39],"21":[40],"patients":[41,155],"with":[42,140,197,203,304,335],"suspected":[43],"RC":[44],"undergoing":[45],"pre-treatment":[46],"PCD-CT":[47,317],"between":[48],"July":[49],"2023":[50],"February":[52],"2025.":[53],"All":[54],"underwent":[55],"a":[56,72,168,286,342,365],"QuantumPlus":[57],"portal":[58],"venous":[59],"phase,":[60],"whose":[61],"3":[62,290,330],"mm/60":[63,291],"keV":[64,253,292,297,340],"reconstruction":[65,136,325],"served":[66],"as":[67,341],"standard":[69],"reference,":[70,142,274],"plus":[71],"separate":[73],"pelvic":[74],"UHR":[75,78,276,316,369],"acquisition.":[76],"Sixteen":[77],"reconstructions":[79],"were":[80,94,121,164,299],"generated":[81],"(0.6\u20133":[82],"mm;":[83],"45\u201370":[84],"keV).":[85,191],"Signal-to-noise":[86],"ratio":[87,90],"(SNR),":[88],"contrast-to-noise":[89],"(CNR)":[91],"noise":[93,195,230,267],"analyzed":[95,122],"using":[96,123],"linear":[97],"mixed-effects":[98],"models.":[99],"Three":[100],"readers":[101],"independently":[102],"rated":[103,247,270,300],"overall":[104,226],"quality,":[106],"perceived":[107,229,266],"noise,":[108],"mesorectal":[109],"fascia":[110],"(MRF)":[111],"sharpness":[112,237],"lesion":[114,239],"conspicuity":[115,240,260],"relative":[116],"to":[117,185],"reference;":[119],"ratings":[120],"mixed":[124],"model":[125],"ordinal":[126],"regression.":[127],"The":[128],"primary":[129],"analysis":[130],"was":[131,151,246,268,358],"within-UHR":[133],"comparison":[134,139],"settings;":[137],"which":[143],"differed":[144,348],"contrast":[146,352],"phase":[147,353],"acquisition":[149,350],"parameters,":[150],"descriptive.":[152],"Results:":[153],"Nineteen":[154],"(mean":[156],"age":[157],"61.7":[158],"\u00b1":[159,180,187],"10.7":[160],"years,":[161],"73.7%":[162],"male)":[163],"included.":[165],"CNR":[166],"showed":[167],"significant":[169],"thickness\u2013ME":[171],"interaction":[173],"(p":[174,231,241],"<":[175,209,220,232],"0.001),":[176],"ranging":[177],"from":[178],"4.85":[179],"2.43":[181],"(3":[182],"mm/45":[183],"keV)":[184],"0.86":[186],"1.04":[188],"(0.6":[189],"mm/70":[190,296],"SNR":[192,277],"increased":[193],"decreased":[196,202],"thicker":[198],"slices,":[199],"while":[200],"both":[201],"higher":[204],"ME":[205,211,312],"levels":[206],"(all":[207,218],"p":[208,219],"0.001).":[210],"influenced":[213],"all":[214,283],"four":[215],"parameters":[217],"0.001);":[221],"significantly":[224],"affected":[225],"0.001)":[233],"but":[234],"not":[235,363],"MRF":[236],"or":[238],"\u2265":[242],"0.115).":[243],"Overall":[244],"favorably":[248,301],"82.9%":[250],"at":[251,256,332,338],"70":[252,339],"versus":[254],"45.6%":[255],"45":[257],"keV.":[258],"Lesion":[259],"reached":[261],"71.9\u201386.0%":[262],"favorable":[263],"ratings,":[264],"whereas":[265],"consistently":[269],"worse":[271],"than":[272],"remained":[278],"below":[279],"reference":[281,347],"settings.":[284],"In":[285],"descriptive":[287],"pooled":[288],"summary,":[289],"(68.0%)":[293],"2":[295,336],"(66.2%)":[298],"most":[302],"often,":[303],"overlapping":[305],"confidence":[306],"intervals.":[307],"Conclusions:":[308],"Slice":[309],"markedly":[314],"RC.":[321],"One":[322],"candidate":[323],"working":[324],"for":[326],"future":[327],"validation":[328],"is":[329],"mm":[331,337],"60":[333],"keV,":[334],"plausible":[343],"alternative.":[344],"Because":[345],"no":[355],"diagnostic":[356,366],"endpoint":[357],"assessed,":[359],"these":[360],"results":[361],"do":[362],"establish":[364],"benefit":[367],"PCD-CT.":[370]},"counts_by_year":[],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2026-11-10T00:00:00"}