{"id":"https://openalex.org/W7225645709","doi":"https://doi.org/10.64898/2026.11.06.26367367","title":"Genomic Studies in Blood and Marrow Transplantation (GS-BMT): An NCI-CIBMTR genomic medicine initiative in hematopoietic cell transplantation","display_name":"Genomic Studies in Blood and Marrow Transplantation (GS-BMT): An NCI-CIBMTR genomic medicine initiative in hematopoietic cell transplantation","publication_year":2026,"publication_date":"2026-11-09","ids":{"openalex":"https://openalex.org/W7225645709","doi":"https://doi.org/10.64898/2026.11.06.26367367"},"language":"en","primary_location":{"id":"doi:10.64898/2026.11.06.26367367","doi":"https://doi.org/10.64898/2026.11.06.26367367","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.11.06.26367367","pdf_url":"https://www.medrxiv.org/content/medrxiv/early/2026/11/09/2026.11.06.26367367.full.pdf","source":{"id":"https://openalex.org/S3005729997","display_name":"medRxiv","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"medRxiv","raw_type":"posted-content"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.medrxiv.org/content/medrxiv/early/2026/11/09/2026.11.06.26367367.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070378721","display_name":"Shahinaz M. Gadalla","orcid":"https://orcid.org/0000-0002-3255-8143","observed_orcids":["https://orcid.org/0000-0002-3255-8143","https://orcid.org/0000-0002-0108-2381"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4391012607","display_name":"Division of Cancer Epidemiology and Genetics","ror":"https://ror.org/00vkwep27","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4391012607"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shahinaz M Gadalla","raw_affiliation_strings":["Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH;"],"raw_orcid":"https://orcid.org/0000-0002-3255-8143","affiliations":[{"raw_affiliation_string":"Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH;","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4391012607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161315515","display_name":"Namhwa Lee","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4391012607","display_name":"Division of Cancer Epidemiology and Genetics","ror":"https://ror.org/00vkwep27","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4391012607"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Namhwa Lee","raw_affiliation_strings":["Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH;","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4391012607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043294149","display_name":"Xueyao Wu","orcid":"https://orcid.org/0000-0001-6856-0520","observed_orcids":["https://orcid.org/0000-0001-6856-0520"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4391012607","display_name":"Division of Cancer Epidemiology and Genetics","ror":"https://ror.org/00vkwep27","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4391012607"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xueyao Wu","raw_affiliation_strings":["Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH;"],"raw_orcid":"https://orcid.org/0000-0001-6856-0520","affiliations":[{"raw_affiliation_string":"Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH;","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4391012607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060248345","display_name":"Filip Pirsl","orcid":"https://orcid.org/0000-0001-7919-0211","observed_orcids":["https://orcid.org/0000-0001-7919-0211"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4391012607","display_name":"Division of Cancer Epidemiology and Genetics","ror":"https://ror.org/00vkwep27","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4391012607"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Filip Pirsl","raw_affiliation_strings":["Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH;"],"raw_orcid":"https://orcid.org/0000-0001-7919-0211","affiliations":[{"raw_affiliation_string":"Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH;","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4391012607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108939079","display_name":"Gabrielle Schmidt","orcid":"https://orcid.org/0009-0001-8866-5319","observed_orcids":["https://orcid.org/0009-0001-8866-5319"]},"institutions":[{"id":"https://openalex.org/I1318116459","display_name":"National Marrow Donor Program","ror":"https://ror.org/016cke005","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1318116459"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gabrielle Schmidt","raw_affiliation_strings":["Center for International Blood and Marrow Transplant Research, National Marrow Donor Program;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for International Blood and Marrow Transplant Research, National Marrow Donor Program;","institution_ids":["https://openalex.org/I1318116459"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009523093","display_name":"Maryam Rafati","orcid":"https://orcid.org/0000-0001-7118-3412","observed_orcids":["https://orcid.org/0000-0001-7118-3412"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4391012607","display_name":"Division of Cancer Epidemiology and Genetics","ror":"https://ror.org/00vkwep27","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4391012607"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Maryam Rafati","raw_affiliation_strings":["Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH;","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4391012607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088697436","display_name":"Amy A Hutchinson","orcid":"https://orcid.org/0000-0002-4962-2711","observed_orcids":["https://orcid.org/0000-0002-4962-2711"]},"institutions":[{"id":"https://openalex.org/I4210130649","display_name":"Frederick National Laboratory for Cancer Research","ror":"https://ror.org/03v6m3209","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210130649","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amy Hutchinson","raw_affiliation_strings":["Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research;","institution_ids":["https://openalex.org/I4210130649"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088723856","display_name":"Aur\u00e9lie L. Vogt","orcid":"https://orcid.org/0000-0003-1257-3095","observed_orcids":["https://orcid.org/0000-0003-1257-3095"]},"institutions":[{"id":"https://openalex.org/I4210130649","display_name":"Frederick National Laboratory for Cancer Research","ror":"https://ror.org/03v6m3209","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210130649","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Aur\u00e9lie Vogt","raw_affiliation_strings":["Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research;","institution_ids":["https://openalex.org/I4210130649"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067533895","display_name":"Belynda D. Hicks","orcid":"https://orcid.org/0000-0001-8014-4888","observed_orcids":["https://orcid.org/0000-0001-8014-4888"]},"institutions":[{"id":"https://openalex.org/I4210130649","display_name":"Frederick National Laboratory for Cancer Research","ror":"https://ror.org/03v6m3209","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210130649","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Belynda Hicks","raw_affiliation_strings":["Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research;","institution_ids":["https://openalex.org/I4210130649"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161336553","display_name":"Jia Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210130649","display_name":"Frederick National Laboratory for Cancer Research","ror":"https://ror.org/03v6m3209","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210130649","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jia Liu","raw_affiliation_strings":["Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research;","institution_ids":["https://openalex.org/I4210130649"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066088353","display_name":"Jiahui Wang","orcid":"https://orcid.org/0000-0002-4855-5094","observed_orcids":["https://orcid.org/0000-0002-4855-5094"]},"institutions":[{"id":"https://openalex.org/I4210130649","display_name":"Frederick National Laboratory for Cancer Research","ror":"https://ror.org/03v6m3209","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210130649","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jiahui Wang","raw_affiliation_strings":["Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research;","institution_ids":["https://openalex.org/I4210130649"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086384605","display_name":"Shilpa Gaddam","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210130649","display_name":"Frederick National Laboratory for Cancer Research","ror":"https://ror.org/03v6m3209","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210130649","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shilpa Gaddam","raw_affiliation_strings":["Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research;","institution_ids":["https://openalex.org/I4210130649"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5133879228","display_name":"Shengchao Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210130649","display_name":"Frederick National Laboratory for Cancer Research","ror":"https://ror.org/03v6m3209","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210130649","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shengchao Li","raw_affiliation_strings":["Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Genomics Research Laboratory, Frederick National Laboratory for Cancer Research;","institution_ids":["https://openalex.org/I4210130649"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058862489","display_name":"Wael Saber","orcid":"https://orcid.org/0000-0002-6544-5815","observed_orcids":["https://orcid.org/0000-0002-6544-5815"]},"institutions":[{"id":"https://openalex.org/I204308271","display_name":"Medical College of Wisconsin","ror":"https://ror.org/00qqv6244","country_code":"US","type":"education","lineage":["https://openalex.org/I204308271"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wael Saber","raw_affiliation_strings":["CIBMTR(R) (Center for National Blood and Marrow Transplant Research), Medical College of Wisconsin;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CIBMTR(R) (Center for National Blood and Marrow Transplant Research), Medical College of Wisconsin;","institution_ids":["https://openalex.org/I204308271"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109737697","display_name":"Stephen Chanock","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4391012607","display_name":"Division of Cancer Epidemiology and Genetics","ror":"https://ror.org/00vkwep27","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4391012607"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stephen Chanock","raw_affiliation_strings":["Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH;","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4391012607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101146176","display_name":"Peter Kraft","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4391012607","display_name":"Division of Cancer Epidemiology and Genetics","ror":"https://ror.org/00vkwep27","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4391012607"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Peter Kraft","raw_affiliation_strings":["Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH;","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4391012607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006363663","display_name":"Sharon A. Savage","orcid":"https://orcid.org/0000-0001-6006-0740","observed_orcids":["https://orcid.org/0000-0001-6006-0740"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4391012607","display_name":"Division of Cancer Epidemiology and Genetics","ror":"https://ror.org/00vkwep27","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4391012607"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Sharon A Savage","raw_affiliation_strings":["Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH;"],"raw_orcid":"https://orcid.org/0000-0001-6006-0740","affiliations":[{"raw_affiliation_string":"Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH;","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4391012607"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003116913","display_name":"Hyokyoung Grace Hong","orcid":"https://orcid.org/0000-0002-4280-6243","observed_orcids":["https://orcid.org/0000-0002-4280-6243"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4391012607","display_name":"Division of Cancer Epidemiology and Genetics","ror":"https://ror.org/00vkwep27","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4391012607"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hyokyoung G Hong","raw_affiliation_strings":["Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH;","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4391012607"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064818358","display_name":"Stephen R. Spellman","orcid":"https://orcid.org/0000-0002-7271-8252","observed_orcids":["https://orcid.org/0000-0002-7271-8252"]},"institutions":[{"id":"https://openalex.org/I1318116459","display_name":"National Marrow Donor Program","ror":"https://ror.org/016cke005","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1318116459"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stephen R Spellman","raw_affiliation_strings":["CIBMTR(R) (Center for International Blood and Marrow Transplant Research), National Marrow Donor Program"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CIBMTR(R) (Center for International Blood and Marrow Transplant Research), National Marrow Donor Program","institution_ids":["https://openalex.org/I1318116459"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5006363663"],"corresponding_institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210140884","https://openalex.org/I4391012607"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.004999999888241291,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10309","display_name":"Acute Myeloid Leukemia Research","score":0.002400000113993883,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hematopoietic-stem-cell-transplantation","display_name":"hematopoietic stem cell transplantation","score":0.996999979019165},{"id":"https://openalex.org/keywords/allogeneic-transplantation","display_name":"allogeneic transplantation","score":0.7870000004768372},{"id":"https://openalex.org/keywords/acute-myeloid-leukemia","display_name":"acute myeloid leukemia","score":0.9800000190734863},{"id":"https://openalex.org/keywords/overall-survival-prediction","display_name":"overall survival prediction","score":0.9470000267028809},{"id":"https://openalex.org/keywords/machine-learning-survival-models","display_name":"machine learning survival models","score":0.7540000081062317},{"id":"https://openalex.org/keywords/clonal-hematopoiesis-of-indeterminate-potential","display_name":"clonal hematopoiesis of indeterminate potential","score":0.9300000071525574},{"id":"https://openalex.org/keywords/polygenic-risk-score","display_name":"polygenic risk score","score":0.9290000200271606},{"id":"https://openalex.org/keywords/donor-selection","display_name":"donor selection","score":0.8650000095367432},{"id":"https://openalex.org/keywords/precision-medicine","display_name":"precision medicine","score":0.5080000162124634},{"id":"https://openalex.org/keywords/cibmtr","display_name":"CIBMTR","score":0.5040000081062317},{"id":"https://openalex.org/keywords/dna-methylation-profiling","display_name":"DNA methylation profiling","score":0.6650000214576721}],"concepts":[{"id":"https://openalex.org/C31467283","wikidata":"https://www.wikidata.org/wiki/Q912147","display_name":"Genotyping","level":4,"score":0.6843000054359436},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.6420000195503235},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6258999705314636},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.600600004196167},{"id":"https://openalex.org/C2993713153","wikidata":"https://www.wikidata.org/wiki/Q211709","display_name":"Hematopoietic cell","level":4,"score":0.5953999757766724},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.45719999074935913},{"id":"https://openalex.org/C50382708","wikidata":"https://www.wikidata.org/wiki/Q223218","display_name":"Proportional hazards model","level":2,"score":0.44369998574256897},{"id":"https://openalex.org/C10515644","wikidata":"https://www.wikidata.org/wiki/Q543310","display_name":"Survival analysis","level":2,"score":0.44020000100135803},{"id":"https://openalex.org/C2777408962","wikidata":"https://www.wikidata.org/wiki/Q1128050","display_name":"Hematopoietic stem cell transplantation","level":3,"score":0.430400013923645},{"id":"https://openalex.org/C2779282312","wikidata":"https://www.wikidata.org/wiki/Q1956561","display_name":"Myeloid","level":2,"score":0.4147999882698059},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.41339999437332153},{"id":"https://openalex.org/C109159458","wikidata":"https://www.wikidata.org/wiki/Q919283","display_name":"Haematopoiesis","level":3,"score":0.392300009727478},{"id":"https://openalex.org/C58041806","wikidata":"https://www.wikidata.org/wiki/Q1660484","display_name":"Imputation (statistics)","level":3,"score":0.3465000092983246},{"id":"https://openalex.org/C3019894029","wikidata":"https://www.wikidata.org/wiki/Q332823","display_name":"Overall survival","level":2,"score":0.34450000524520874},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.33739998936653137},{"id":"https://openalex.org/C163763905","wikidata":"https://www.wikidata.org/wiki/Q17075943","display_name":"Precision medicine","level":2,"score":0.3228999972343445},{"id":"https://openalex.org/C189206191","wikidata":"https://www.wikidata.org/wiki/Q222046","display_name":"Genomics","level":4,"score":0.3111000061035156},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.30730000138282776},{"id":"https://openalex.org/C2778729363","wikidata":"https://www.wikidata.org/wiki/Q11688946","display_name":"Myeloid leukemia","level":2,"score":0.3066999912261963},{"id":"https://openalex.org/C129848803","wikidata":"https://www.wikidata.org/wiki/Q2564360","display_name":"Sample size determination","level":2,"score":0.2833000123500824},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2824999988079071},{"id":"https://openalex.org/C2908731994","wikidata":"https://www.wikidata.org/wiki/Q2509220","display_name":"Hematologic Neoplasms","level":3,"score":0.2732999920845032},{"id":"https://openalex.org/C106208931","wikidata":"https://www.wikidata.org/wiki/Q1098876","display_name":"Genome-wide association study","level":5,"score":0.26969999074935913},{"id":"https://openalex.org/C113968399","wikidata":"https://www.wikidata.org/wiki/Q7559241","display_name":"Somatic evolution in cancer","level":3,"score":0.265500009059906},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.26330000162124634},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.26159998774528503},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.26010000705718994},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.25040000677108765}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.64898/2026.11.06.26367367","doi":"https://doi.org/10.64898/2026.11.06.26367367","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.11.06.26367367","pdf_url":"https://www.medrxiv.org/content/medrxiv/early/2026/11/09/2026.11.06.26367367.full.pdf","source":{"id":"https://openalex.org/S3005729997","display_name":"medRxiv","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"medRxiv","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.64898/2026.11.06.26367367","doi":"https://doi.org/10.64898/2026.11.06.26367367","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.11.06.26367367","pdf_url":"https://www.medrxiv.org/content/medrxiv/early/2026/11/09/2026.11.06.26367367.full.pdf","source":{"id":"https://openalex.org/S3005729997","display_name":"medRxiv","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"repository"},"license":"public-domain","license_id":"https://openalex.org/licenses/public-domain","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"medRxiv","raw_type":"posted-content"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332175","display_name":"Health Resources and Services Administration","ror":"https://ror.org/033jnv181"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7225645709.pdf","grobid_xml":"https://content.openalex.org/works/W7225645709.grobid-xml"},"referenced_works_count":31,"referenced_works":["https://openalex.org/W2012131456","https://openalex.org/W2014680443","https://openalex.org/W2058210607","https://openalex.org/W2478324813","https://openalex.org/W2749245452","https://openalex.org/W2795973794","https://openalex.org/W2913997948","https://openalex.org/W3017383148","https://openalex.org/W3023020261","https://openalex.org/W3089104877","https://openalex.org/W3097385677","https://openalex.org/W3121459834","https://openalex.org/W3157123648","https://openalex.org/W3193334190","https://openalex.org/W4237500481","https://openalex.org/W4281557525","https://openalex.org/W4283773131","https://openalex.org/W4285387237","https://openalex.org/W4291820501","https://openalex.org/W4297461622","https://openalex.org/W4310439055","https://openalex.org/W4389346648","https://openalex.org/W4402378986","https://openalex.org/W4408258997","https://openalex.org/W4408907505","https://openalex.org/W4410494991","https://openalex.org/W4411141180","https://openalex.org/W4414781445","https://openalex.org/W4415295952","https://openalex.org/W4415944590","https://openalex.org/W7126098592"],"related_works":["https://openalex.org/W7172351990","https://openalex.org/W2979986443","https://openalex.org/W4310106493","https://openalex.org/W2058210607","https://openalex.org/W2147426382","https://openalex.org/W2147999797","https://openalex.org/W2906695778","https://openalex.org/W4412774247","https://openalex.org/W2980283429","https://openalex.org/W3193334190"],"abstract_inverted_index":{"Background:":[0],"Genomic":[1,18],"studies":[2],"in":[3,20,90,128,181,247],"hematopoietic":[4],"cell":[5],"transplantation":[6],"(HCT)":[7],"are":[8,50],"limited":[9],"by":[10,174,200],"sample":[11],"sizes":[12],"and":[13,22,36,43,58,60,70,73,81,98,134,157,165,209,244],"targeted":[14],"approaches.":[15],"Methods:":[16],"The":[17],"Studies":[19],"Blood":[21],"Marrow":[23],"Transplantation":[24],"(GS-BMT)":[25],"project":[26],"is":[27],"a":[28,223,232],"collaboration":[29],"between":[30,132],"the":[31,37,129,206,212,220,226],"National":[32],"Cancer":[33],"Institute":[34],"(NCI)":[35],"CIBMTR":[38],"designed":[39],"to":[40,103,237],"investigate":[41],"recipient":[42],"donor":[44,224,242],"determinants":[45],"of":[46,79,85,100,106,197,211,222],"HCT":[47,89,112,127],"outcomes.":[48],"We":[49,66],"generating":[51],"genome-wide":[52],"SNP-array":[53],"genotyping":[54],"for":[55,63,144,150],"all":[56],"samples,":[57],"sequencing":[59],"methylation":[61],"profiling":[62],"selected":[64],"subsets.":[65],"report":[67],"study":[68],"design":[69],"cohort":[71],"characteristics":[72],"present":[74],"two":[75],"proof-of-concept":[76],"analyses:":[77],"comparison":[78],"conventional":[80],"machine":[82],"learning":[83],"prediction":[84,143],"overall":[86],"survival":[87,155,161],"after":[88],"9,262":[91],"patients":[92],"with":[93,147,225],"acute":[94],"myeloid":[95],"leukemia":[96],"(AML),":[97],"assessment":[99],"inherited":[101],"susceptibility":[102],"clonal":[104],"hematopoiesis":[105],"indeterminate":[107],"potential":[108],"(CHIP)":[109],"among":[110],"19,750":[111],"donors":[113,185],"using":[114],"polygenic":[115],"scores":[116],"(PGS).":[117],"Results:":[118],"GS-BMT":[119,230],"includes":[120],"30,718":[121],"donor-recipient":[122],"pairs":[123],"who":[124],"received":[125],"allogeneic":[126],"United":[130],"States":[131],"2000":[133],"2019.":[135],"In":[136,168,191],"AML,":[137],"clinical":[138],"variables":[139],"alone":[140],"provided":[141],"modest":[142],"post-transplant":[145],"survival,":[146],"similar":[148],"performance":[149],"Cox":[151],"proportional":[152],"hazards,":[153],"random":[154],"forest,":[156],"deep":[158],"neural":[159],"network":[160],"models":[162],"(C-index=0.63,":[163],"0.62,":[164,166],"respectively).":[167],"donors,":[169,213],"CHIP-PGS":[170],"did":[171],"not":[172],"differ":[173],"age":[175],"(p=0.76)":[176],"but":[177],"was":[178],"modestly":[179],"lower":[180],"unrelated":[182],"vs.":[183],"related":[184],"(-0.06":[186],"standard":[187],"deviation":[188],"[SD];":[189],"p=0.002).":[190],"an":[192],"illustrative":[193],"analysis":[194],"assuming":[195],"risk":[196,221,240],"event":[198],"increases":[199],"50%":[201],"or":[202],"80%":[203],"per":[204],"PGS-SD,":[205],"top":[207],"5.2%":[208],"12.3%":[210],"respectively,":[214],"would":[215],"have":[216],"at":[217],"least":[218],"twice":[219],"average":[227],"PGS.":[228],"Conclusions:":[229],"establishes":[231],"large":[233],"genomic":[234],"platform":[235],"aiming":[236],"improve":[238],"individualized":[239],"prediction,":[241],"selection,":[243],"precision":[245],"medicine":[246],"HCT.":[248]},"counts_by_year":[],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2026-11-10T00:00:00"}