{"id":"https://openalex.org/W7225636534","doi":"https://doi.org/10.3390/jcm15218737","title":"Artificial Intelligence in Pancreatic Resection: Current Evidence, Surgical Applications, and a Framework for Clinical Translation","display_name":"Artificial Intelligence in Pancreatic Resection: Current Evidence, Surgical Applications, and a Framework for Clinical Translation","publication_year":2026,"publication_date":"2026-11-09","ids":{"openalex":"https://openalex.org/W7225636534","doi":"https://doi.org/10.3390/jcm15218737"},"language":"en","primary_location":{"id":"doi:10.3390/jcm15218737","doi":"https://doi.org/10.3390/jcm15218737","is_oa":true,"landing_page_url":"https://doi.org/10.3390/jcm15218737","pdf_url":null,"source":{"id":"https://openalex.org/S2737969411","display_name":"Journal of Clinical Medicine","issn_l":"2077-0383","issn":["2077-0383"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","ki-jl-1","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.3390/jcm15218737","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5120462698","display_name":"Karim Heiba","orcid":"https://orcid.org/0009-0005-6636-9059","observed_orcids":["https://orcid.org/0009-0005-6636-9059"]},"institutions":[{"id":"https://openalex.org/I4210161870","display_name":"Royal Blackburn Teaching Hospital","ror":"https://ror.org/05261sq16","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210161870","https://openalex.org/I67218396"]},{"id":"https://openalex.org/I67218396","display_name":"East Lancashire Hospitals NHS Trust","ror":"https://ror.org/002pa9318","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I67218396"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Karim Heiba","raw_affiliation_strings":["Department of General Surgery, Royal Blackburn Teaching Hospital, East Lancashire Hospitals NHS Trust, Haslingden Road, Blackburn BB2 3HH, UK"],"raw_orcid":"https://orcid.org/0009-0005-6636-9059","affiliations":[{"raw_affiliation_string":"Department of General Surgery, Royal Blackburn Teaching Hospital, East Lancashire Hospitals NHS Trust, Haslingden Road, Blackburn BB2 3HH, UK","institution_ids":["https://openalex.org/I4210161870","https://openalex.org/I67218396"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5075866792","display_name":"Ambareen Kausar","orcid":"https://orcid.org/0000-0003-0234-9321","observed_orcids":["https://orcid.org/0000-0003-0234-9321"]},"institutions":[{"id":"https://openalex.org/I4210161870","display_name":"Royal Blackburn Teaching Hospital","ror":"https://ror.org/05261sq16","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210161870","https://openalex.org/I67218396"]},{"id":"https://openalex.org/I67218396","display_name":"East Lancashire Hospitals NHS Trust","ror":"https://ror.org/002pa9318","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I67218396"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Ambareen Kausar","raw_affiliation_strings":["Department of General Surgery, Royal Blackburn Teaching Hospital, East Lancashire Hospitals NHS Trust, Haslingden Road, Blackburn BB2 3HH, UK"],"raw_orcid":"https://orcid.org/0000-0003-0234-9321","affiliations":[{"raw_affiliation_string":"Department of General Surgery, Royal Blackburn Teaching Hospital, East Lancashire Hospitals NHS Trust, Haslingden Road, Blackburn BB2 3HH, UK","institution_ids":["https://openalex.org/I4210161870","https://openalex.org/I67218396"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5075866792"],"corresponding_institution_ids":["https://openalex.org/I4210161870","https://openalex.org/I67218396"],"apc_list":{"value":2600,"currency":"CHF","value_usd":3137},"apc_paid":{"value":2600,"currency":"CHF","value_usd":3137},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"15","issue":"21","first_page":"8737","last_page":"8737"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11636","display_name":"Artificial Intelligence in Healthcare and Education","score":0.6660000085830688,"subfield":{"id":"https://openalex.org/subfields/2718","display_name":"Health Informatics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11636","display_name":"Artificial Intelligence in Healthcare and Education","score":0.6660000085830688,"subfield":{"id":"https://openalex.org/subfields/2718","display_name":"Health Informatics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10231","display_name":"Pancreatic and Hepatic Oncology Research","score":0.2621999979019165,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.03009999915957451,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"artificial intelligence","score":0.9779999852180481},{"id":"https://openalex.org/keywords/pancreatectomy","display_name":"pancreatic resection","score":0.9959999918937683},{"id":"https://openalex.org/keywords/postoperative-pancreatic-fistula","display_name":"postoperative pancreatic fistula","score":0.8799999952316284},{"id":"https://openalex.org/keywords/pancreaticoduodenectomy","display_name":"pancreaticoduodenectomy","score":0.9760000109672546},{"id":"https://openalex.org/keywords/distal-pancreatectomy","display_name":"distal pancreatectomy","score":0.9980000257492065},{"id":"https://openalex.org/keywords/risk-prediction","display_name":"risk prediction","score":0.6660000085830688},{"id":"https://openalex.org/keywords/surgical-planning","display_name":"surgical planning","score":0.8489999771118164},{"id":"https://openalex.org/keywords/surgical-margin-assessment","display_name":"surgical margin assessment","score":0.6460000276565552},{"id":"https://openalex.org/keywords/external-validation","display_name":"external validation","score":0.8220000267028809},{"id":"https://openalex.org/keywords/clinical-translation","display_name":"clinical translation","score":0.890999972820282},{"id":"https://openalex.org/keywords/clinical-decision-support","display_name":"clinical decision support","score":0.5400000214576721}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.947700023651123},{"id":"https://openalex.org/C31174226","wikidata":"https://www.wikidata.org/wiki/Q64855140","display_name":"Perioperative","level":2,"score":0.6420999765396118},{"id":"https://openalex.org/C2780911694","wikidata":"https://www.wikidata.org/wiki/Q7130409","display_name":"Pancreatic fistula","level":3,"score":0.5645999908447266},{"id":"https://openalex.org/C177212765","wikidata":"https://www.wikidata.org/wiki/Q627335","display_name":"Workflow","level":2,"score":0.41830000281333923},{"id":"https://openalex.org/C774472","wikidata":"https://www.wikidata.org/wiki/Q6760393","display_name":"Margin (machine learning)","level":2,"score":0.4115000069141388},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.38269999623298645},{"id":"https://openalex.org/C2779974597","wikidata":"https://www.wikidata.org/wiki/Q28448986","display_name":"Clinical Practice","level":2,"score":0.3587999939918518},{"id":"https://openalex.org/C19527891","wikidata":"https://www.wikidata.org/wiki/Q1120908","display_name":"Medical physics","level":1,"score":0.3538999855518341},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.3474000096321106},{"id":"https://openalex.org/C3020000205","wikidata":"https://www.wikidata.org/wiki/Q2412849","display_name":"Narrative review","level":2,"score":0.3463999927043915},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.3422999978065491},{"id":"https://openalex.org/C2776341189","wikidata":"https://www.wikidata.org/wiki/Q189470","display_name":"Fistula","level":2,"score":0.3361999988555908},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.33340001106262207},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3285999894142151},{"id":"https://openalex.org/C63363279","wikidata":"https://www.wikidata.org/wiki/Q5133848","display_name":"Clinical significance","level":2,"score":0.3212999999523163},{"id":"https://openalex.org/C159110652","wikidata":"https://www.wikidata.org/wiki/Q17078201","display_name":"Resection","level":2,"score":0.299699991941452},{"id":"https://openalex.org/C61434518","wikidata":"https://www.wikidata.org/wiki/Q932510","display_name":"General surgery","level":1,"score":0.2824000120162964},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.28220000863075256},{"id":"https://openalex.org/C198433322","wikidata":"https://www.wikidata.org/wiki/Q3910099","display_name":"Predictive value of tests","level":2,"score":0.27709999680519104},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.26829999685287476},{"id":"https://openalex.org/C2778132481","wikidata":"https://www.wikidata.org/wiki/Q7646216","display_name":"Resection margin","level":3,"score":0.2671999931335449},{"id":"https://openalex.org/C2776737053","wikidata":"https://www.wikidata.org/wiki/Q7130407","display_name":"Pancreatic disease","level":3,"score":0.25999999046325684},{"id":"https://openalex.org/C19648533","wikidata":"https://www.wikidata.org/wiki/Q691640","display_name":"Evidence-based medicine","level":3,"score":0.2597000002861023}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.3390/jcm15218737","doi":"https://doi.org/10.3390/jcm15218737","is_oa":true,"landing_page_url":"https://doi.org/10.3390/jcm15218737","pdf_url":null,"source":{"id":"https://openalex.org/S2737969411","display_name":"Journal of Clinical Medicine","issn_l":"2077-0383","issn":["2077-0383"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","ki-jl-1","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Medicine","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.3390/jcm15218737","doi":"https://doi.org/10.3390/jcm15218737","is_oa":true,"landing_page_url":"https://doi.org/10.3390/jcm15218737","pdf_url":null,"source":{"id":"https://openalex.org/S2737969411","display_name":"Journal of Clinical Medicine","issn_l":"2077-0383","issn":["2077-0383"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","ki-jl-1","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9940000176429749}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":81,"referenced_works":["https://openalex.org/W2028636108","https://openalex.org/W2174661749","https://openalex.org/W2277400190","https://openalex.org/W2514561022","https://openalex.org/W2565595087","https://openalex.org/W2580456502","https://openalex.org/W2772421529","https://openalex.org/W2903443299","https://openalex.org/W2989361460","https://openalex.org/W2998789541","https://openalex.org/W2999253222","https://openalex.org/W3017047615","https://openalex.org/W3048617165","https://openalex.org/W3049412722","https://openalex.org/W3136031576","https://openalex.org/W3136280493","https://openalex.org/W3148832799","https://openalex.org/W3158534674","https://openalex.org/W3202328699","https://openalex.org/W3210838703","https://openalex.org/W3214304393","https://openalex.org/W4200151248","https://openalex.org/W4221123918","https://openalex.org/W4225125635","https://openalex.org/W4229020567","https://openalex.org/W4280572991","https://openalex.org/W4296629365","https://openalex.org/W4307475642","https://openalex.org/W4317754037","https://openalex.org/W4321178906","https://openalex.org/W4366982318","https://openalex.org/W4372218811","https://openalex.org/W4376131968","https://openalex.org/W4385622553","https://openalex.org/W4387439407","https://openalex.org/W4387569829","https://openalex.org/W4388079918","https://openalex.org/W4388574314","https://openalex.org/W4390263004","https://openalex.org/W4392202846","https://openalex.org/W4392355173","https://openalex.org/W4392847683","https://openalex.org/W4394857110","https://openalex.org/W4399128032","https://openalex.org/W4399187332","https://openalex.org/W4400281217","https://openalex.org/W4401799354","https://openalex.org/W4402239181","https://openalex.org/W4402927686","https://openalex.org/W4405740211","https://openalex.org/W4405912363","https://openalex.org/W4406692022","https://openalex.org/W4407789827","https://openalex.org/W4408800520","https://openalex.org/W4408806526","https://openalex.org/W4408921896","https://openalex.org/W4409119784","https://openalex.org/W4409149110","https://openalex.org/W4410007559","https://openalex.org/W4410008049","https://openalex.org/W4410195508","https://openalex.org/W4410966754","https://openalex.org/W4411291450","https://openalex.org/W4411711347","https://openalex.org/W4412488296","https://openalex.org/W4415150066","https://openalex.org/W4415879780","https://openalex.org/W4416067502","https://openalex.org/W4416324710","https://openalex.org/W4416775113","https://openalex.org/W4416980948","https://openalex.org/W7116654149","https://openalex.org/W7127042418","https://openalex.org/W7128601028","https://openalex.org/W7130865251","https://openalex.org/W7141632905","https://openalex.org/W7154158274","https://openalex.org/W7156366912","https://openalex.org/W7164736844","https://openalex.org/W7167583858","https://openalex.org/W7168124251"],"related_works":["https://openalex.org/W7223904574","https://openalex.org/W7203530986","https://openalex.org/W7221104099","https://openalex.org/W4366982318","https://openalex.org/W4409082617","https://openalex.org/W4214858411","https://openalex.org/W3049412722","https://openalex.org/W3174288101","https://openalex.org/W3014030290","https://openalex.org/W7132836312"],"abstract_inverted_index":{"Introduction:":[0],"Pancreatic":[1],"resection":[2,43,162],"remains":[3],"technically":[4],"demanding,":[5],"with":[6,53,92,116,177],"clinically":[7],"relevant":[8],"postoperative":[9,30],"pancreatic":[10,42,161],"fistula":[11],"(CR-POPF)":[12],"a":[13],"major":[14],"source":[15],"of":[16,57],"morbidity.":[17],"Artificial":[18],"intelligence":[19],"(AI)":[20],"may":[21],"support":[22],"risk":[23],"stratification,":[24],"operative":[25],"planning,":[26,107,167],"intraoperative":[27,109],"assessment,":[28,104],"and":[29,44,65,80,102,108,111,123,134,150,168,184,187],"decision":[31],"support.":[32],"This":[33],"focused":[34],"narrative":[35],"review":[36],"evaluates":[37],"current":[38],"AI":[39,159,192],"applications":[40],"in":[41,95,160],"their":[45],"translational":[46],"maturity.":[47,82],"Methods:":[48],"A":[49],"structured":[50],"PubMed/MEDLINE":[51],"search":[52],"an":[54],"evidence":[55],"cutoff":[56],"24":[58],"July":[59],"2026":[60],"was":[61],"supplemented":[62],"by":[63,75,87],"backward":[64],"forward":[66],"citation":[67],"tracking.":[68],"Seventy":[69],"eligible":[70],"primary":[71],"reports":[72],"were":[73,137,142],"synthesised":[74],"clinical":[76,135,178],"task,":[77],"information":[78],"timing,":[79,120],"validation":[81,124,127],"Results:":[83],"Evidence":[84],"is":[85,163],"dominated":[86],"CR-POPF":[88],"prediction":[89],"after":[90],"pancreatoduodenectomy,":[91],"additional":[93],"studies":[94,141,189],"distal":[96],"pancreatectomy,":[97],"other":[98],"perioperative":[99],"outcomes,":[100],"tissue":[101],"margin":[103],"three-dimensional":[105],"anatomical":[106],"video":[110],"anatomy":[112],"recognition.":[113],"Performance":[114],"varied":[115],"patient":[117],"selection,":[118],"predictor":[119],"data":[121],"modality,":[122],"strategy.":[125],"External":[126],"often":[128],"changed":[129],"reported":[130],"discrimination,":[131],"while":[132],"calibration":[133],"utility":[136],"inconsistently":[138],"reported.":[139],"Most":[140],"retrospective":[143],"or":[144],"technical;":[145],"overlapping":[146],"cohorts":[147],"limited":[148],"independence,":[149],"no":[151],"included":[152],"study":[153],"demonstrated":[154],"improved":[155],"patient-centred":[156],"outcomes.":[157],"Conclusions:":[158],"expanding":[164],"across":[165],"prediction,":[166],"guidance,":[169],"but":[170],"technical":[171],"performance":[172],"should":[173,193],"not":[174],"be":[175],"equated":[176],"readiness.":[179],"Independent":[180],"validation,":[181],"prospective":[182],"workflow":[183],"human-factors":[185],"evaluation,":[186],"clinical-impact":[188],"are":[190],"needed.":[191],"augment,":[194],"rather":[195],"than":[196],"replace,":[197],"specialist":[198],"surgical":[199],"judgement.":[200]},"counts_by_year":[],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2026-11-10T00:00:00"}