{"id":"https://openalex.org/W7225636287","doi":"https://doi.org/10.1001/jamanetworkopen.2026.42912","title":"Neighborhood Social Disadvantage and Lung Aging and Mortality","display_name":"Neighborhood Social Disadvantage and Lung Aging and Mortality","publication_year":2026,"publication_date":"2026-11-09","ids":{"openalex":"https://openalex.org/W7225636287","doi":"https://doi.org/10.1001/jamanetworkopen.2026.42912","pmid":"https://pubmed.ncbi.nlm.nih.gov/43002398"},"language":"en","primary_location":{"id":"doi:10.1001/jamanetworkopen.2026.42912","doi":"https://doi.org/10.1001/jamanetworkopen.2026.42912","is_oa":true,"landing_page_url":"https://doi.org/10.1001/jamanetworkopen.2026.42912","pdf_url":"https://jamanetwork.com/journals/jamanetworkopen/articlepdf/2856344/wu_2026_oi_261154_1793633566.67135.pdf","source":{"id":"https://openalex.org/S4210217848","display_name":"JAMA Network Open","issn_l":"2574-3805","issn":["2574-3805"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-2","medline","norway-1","oarl","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320259","host_organization_name":"American Medical Association","host_organization_lineage":["https://openalex.org/P4310320259"],"host_organization_lineage_names":["American Medical Association"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JAMA Network Open","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://jamanetwork.com/journals/jamanetworkopen/articlepdf/2856344/wu_2026_oi_261154_1793633566.67135.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5122913184","display_name":"Qizhen Wu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I169521973","display_name":"University of New Mexico","ror":"https://ror.org/05fs6jp91","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973"]},{"id":"https://openalex.org/I4390039284","display_name":"UNM Comprehensive Cancer Center","ror":"https://ror.org/05kx2e072","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I169521973","https://openalex.org/I4390039284"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Qizhen Wu","raw_affiliation_strings":["Comprehensive Cancer Center, University of New Mexico, Albuquerque"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Comprehensive Cancer Center, University of New Mexico, Albuquerque","institution_ids":["https://openalex.org/I169521973","https://openalex.org/I4390039284"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102961201","display_name":"Yan Huang","orcid":"https://orcid.org/0000-0001-8482-5357","observed_orcids":["https://orcid.org/0000-0001-8482-5357"]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yanhong Huang","raw_affiliation_strings":["Department of Biobehavioral Health, Pennsylvania State University, University Park"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biobehavioral Health, Pennsylvania State University, University Park","institution_ids":["https://openalex.org/I130769515"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045408169","display_name":"Maria A. Picchi","orcid":"https://orcid.org/0000-0003-1067-0916","observed_orcids":["https://orcid.org/0000-0003-1067-0916"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Maria A. Picchi","raw_affiliation_strings":["Lung Cancer Program, Lovelace Biomedical Research Institute, Albuquerque, New Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lung Cancer Program, Lovelace Biomedical Research Institute, Albuquerque, New Mexico","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5121601817","display_name":"Elizabeth Y. Jimenez","orcid":"https://orcid.org/0000-0003-0315-7022","observed_orcids":["https://orcid.org/0000-0003-0315-7022"]},"institutions":[{"id":"https://openalex.org/I169521973","display_name":"University of New Mexico","ror":"https://ror.org/05fs6jp91","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973"]},{"id":"https://openalex.org/I4405255059","display_name":"University of New Mexico Health Sciences Center","ror":"https://ror.org/02jvjmd55","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973","https://openalex.org/I4405255059"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elizabeth Y. Jimenez","raw_affiliation_strings":["College of Population Health, University of New Mexico Health Sciences Center, Albuquerque"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Population Health, University of New Mexico Health Sciences Center, Albuquerque","institution_ids":["https://openalex.org/I169521973","https://openalex.org/I4405255059"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5136317100","display_name":"Yue Feng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I169521973","display_name":"University of New Mexico","ror":"https://ror.org/05fs6jp91","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973"]},{"id":"https://openalex.org/I4390039284","display_name":"UNM Comprehensive Cancer Center","ror":"https://ror.org/05kx2e072","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I169521973","https://openalex.org/I4390039284"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yue Feng","raw_affiliation_strings":["Comprehensive Cancer Center, University of New Mexico, Albuquerque"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Comprehensive Cancer Center, University of New Mexico, Albuquerque","institution_ids":["https://openalex.org/I169521973","https://openalex.org/I4390039284"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080346583","display_name":"Steven A. Belinsky","orcid":"https://orcid.org/0000-0002-1240-2504","observed_orcids":["https://orcid.org/0000-0002-1240-2504"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Steven A. Belinsky","raw_affiliation_strings":["Lung Cancer Program, Lovelace Biomedical Research Institute, Albuquerque, New Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lung Cancer Program, Lovelace Biomedical Research Institute, Albuquerque, New Mexico","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161327875","display_name":"Yan Lin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yan Lin","raw_affiliation_strings":["Department of Geography, Pennsylvania State University, University Park","Social Science Research Institute, Pennsylvania State University, University Park"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Geography, Pennsylvania State University, University Park","institution_ids":["https://openalex.org/I130769515"]},{"raw_affiliation_string":"Social Science Research Institute, Pennsylvania State University, University Park","institution_ids":["https://openalex.org/I130769515"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088891117","display_name":"V. Shane Pankratz","orcid":"https://orcid.org/0000-0002-3742-040X","observed_orcids":["https://orcid.org/0000-0002-3742-040X"]},"institutions":[{"id":"https://openalex.org/I169521973","display_name":"University of New Mexico","ror":"https://ror.org/05fs6jp91","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973"]},{"id":"https://openalex.org/I4390039284","display_name":"UNM Comprehensive Cancer Center","ror":"https://ror.org/05kx2e072","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I169521973","https://openalex.org/I4390039284"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Vernon S. Pankratz","raw_affiliation_strings":["Comprehensive Cancer Center, University of New Mexico, Albuquerque","Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Comprehensive Cancer Center, University of New Mexico, Albuquerque","institution_ids":["https://openalex.org/I169521973","https://openalex.org/I4390039284"]},{"raw_affiliation_string":"Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque","institution_ids":["https://openalex.org/I169521973"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5157849095","display_name":"Akshay Sood","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I169521973","display_name":"University of New Mexico","ror":"https://ror.org/05fs6jp91","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Akshay Sood","raw_affiliation_strings":["Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque","institution_ids":["https://openalex.org/I169521973"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042115750","display_name":"Roberta Proffitt Lavin","orcid":"https://orcid.org/0000-0001-6106-8066","observed_orcids":["https://orcid.org/0000-0001-6106-8066"]},"institutions":[{"id":"https://openalex.org/I169521973","display_name":"University of New Mexico","ror":"https://ror.org/05fs6jp91","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Roberta P. Lavin","raw_affiliation_strings":["College of Nursing, University of New Mexico, Albuquerque"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Nursing, University of New Mexico, Albuquerque","institution_ids":["https://openalex.org/I169521973"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161354440","display_name":"Xi Gong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I130769515","display_name":"Pennsylvania State University","ror":"https://ror.org/04p491231","country_code":"US","type":"education","lineage":["https://openalex.org/I130769515"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xi Gong","raw_affiliation_strings":["Department of Biobehavioral Health, Pennsylvania State University, University Park","Institute for Computational and Data Sciences, Pennsylvania State University, University Park"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biobehavioral Health, Pennsylvania State University, University Park","institution_ids":["https://openalex.org/I130769515"]},{"raw_affiliation_string":"Institute for Computational and Data Sciences, Pennsylvania State University, University Park","institution_ids":["https://openalex.org/I130769515"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5102736680","display_name":"Shuguang Leng","orcid":"https://orcid.org/0000-0002-9860-8158","observed_orcids":["https://orcid.org/0000-0002-9860-8158"]},"institutions":[{"id":"https://openalex.org/I169521973","display_name":"University of New Mexico","ror":"https://ror.org/05fs6jp91","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973"]},{"id":"https://openalex.org/I4390039284","display_name":"UNM Comprehensive Cancer Center","ror":"https://ror.org/05kx2e072","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I169521973","https://openalex.org/I4390039284"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Shuguang Leng","raw_affiliation_strings":["Comprehensive Cancer Center, University of New Mexico, Albuquerque","Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Comprehensive Cancer Center, University of New Mexico, Albuquerque","institution_ids":["https://openalex.org/I169521973","https://openalex.org/I4390039284"]},{"raw_affiliation_string":"Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque","institution_ids":["https://openalex.org/I169521973"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5102736680"],"corresponding_institution_ids":["https://openalex.org/I169521973","https://openalex.org/I4390039284"],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":{"value":3000,"currency":"USD","value_usd":3000},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"9","issue":"11","first_page":"e2642912","last_page":"e2642912"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10235","display_name":"Health disparities and outcomes","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/3306","display_name":"Health"},"field":{"id":"https://openalex.org/fields/33","display_name":"Social Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T10235","display_name":"Health disparities and outcomes","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/3306","display_name":"Health"},"field":{"id":"https://openalex.org/fields/33","display_name":"Social Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12259","display_name":"Environmental Justice and Health Disparities","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/3312","display_name":"Sociology and Political Science"},"field":{"id":"https://openalex.org/fields/33","display_name":"Social Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lung-aging","display_name":"lung aging","score":0.6620000004768372},{"id":"https://openalex.org/keywords/lung-function-decline","display_name":"lung function decline","score":0.968999981880188},{"id":"https://openalex.org/keywords/health-related-quality-of-life","display_name":"health-related quality of life","score":0.8410000205039978},{"id":"https://openalex.org/keywords/all-cause-mortality","display_name":"all-cause mortality","score":0.972000002861023},{"id":"https://openalex.org/keywords/smokers","display_name":"smokers","score":0.6399999856948853},{"id":"https://openalex.org/keywords/social-vulnerability-index","display_name":"Social Vulnerability Index","score":0.9670000076293945},{"id":"https://openalex.org/keywords/social-deprivation-index","display_name":"social deprivation index","score":0.996999979019165},{"id":"https://openalex.org/keywords/fev1-fvc-ratio","display_name":"FEV1/FVC ratio","score":0.8489999771118164},{"id":"https://openalex.org/keywords/eating-habits","display_name":"dietary habits","score":0.5960000157356262},{"id":"https://openalex.org/keywords/health-disparities","display_name":"health disparities","score":0.6420000195503235},{"id":"https://openalex.org/keywords/spirometry","display_name":"spirometry","score":0.49799999594688416},{"id":"https://openalex.org/keywords/st-george-s-respiratory-questionnaire","display_name":"St George's Respiratory Questionnaire","score":0.8130000233650208}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7570000290870667},{"id":"https://openalex.org/C2780333948","wikidata":"https://www.wikidata.org/wiki/Q653305","display_name":"Spirometry","level":3,"score":0.6790000200271606},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.5641000270843506},{"id":"https://openalex.org/C2777895361","wikidata":"https://www.wikidata.org/wiki/Q1758614","display_name":"Longitudinal study","level":2,"score":0.5468999743461609},{"id":"https://openalex.org/C55520419","wikidata":"https://www.wikidata.org/wiki/Q660995","display_name":"Vital capacity","level":5,"score":0.5307000279426575},{"id":"https://openalex.org/C74909509","wikidata":"https://www.wikidata.org/wiki/Q10387","display_name":"Gerontology","level":1,"score":0.513700008392334},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.49540001153945923},{"id":"https://openalex.org/C3018587741","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung function","level":3,"score":0.48980000615119934},{"id":"https://openalex.org/C2779951463","wikidata":"https://www.wikidata.org/wiki/Q7268788","display_name":"Quality of life (healthcare)","level":2,"score":0.4593000113964081},{"id":"https://openalex.org/C2777654188","wikidata":"https://www.wikidata.org/wiki/Q16947724","display_name":"National Death Index","level":4,"score":0.44429999589920044},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.41110000014305115},{"id":"https://openalex.org/C2779501324","wikidata":"https://www.wikidata.org/wiki/Q581445","display_name":"Social vulnerability","level":3,"score":0.40790000557899475},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.3889000117778778},{"id":"https://openalex.org/C179420905","wikidata":"https://www.wikidata.org/wiki/Q223871","display_name":"Mediation","level":2,"score":0.37369999289512634},{"id":"https://openalex.org/C27101514","wikidata":"https://www.wikidata.org/wiki/Q206120","display_name":"Lung volumes","level":3,"score":0.34220001101493835},{"id":"https://openalex.org/C147077947","wikidata":"https://www.wikidata.org/wiki/Q1515895","display_name":"Socioeconomic status","level":3,"score":0.3301999866962433},{"id":"https://openalex.org/C13543017","wikidata":"https://www.wikidata.org/wiki/Q4430231","display_name":"Social deprivation","level":2,"score":0.32910001277923584},{"id":"https://openalex.org/C3020672099","wikidata":"https://www.wikidata.org/wiki/Q857354","display_name":"Longitudinal data","level":2,"score":0.32179999351501465},{"id":"https://openalex.org/C110888244","wikidata":"https://www.wikidata.org/wiki/Q187588","display_name":"Social class","level":2,"score":0.3138999938964844},{"id":"https://openalex.org/C133925201","wikidata":"https://www.wikidata.org/wiki/Q188419","display_name":"Life expectancy","level":3,"score":0.3089999854564667},{"id":"https://openalex.org/C12725497","wikidata":"https://www.wikidata.org/wiki/Q810247","display_name":"Baseline (sea)","level":2,"score":0.2985000014305115},{"id":"https://openalex.org/C75603125","wikidata":"https://www.wikidata.org/wiki/Q1877462","display_name":"Pulmonary function testing","level":2,"score":0.29679998755455017},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.29159998893737793},{"id":"https://openalex.org/C95713431","wikidata":"https://www.wikidata.org/wiki/Q631425","display_name":"Vulnerability (computing)","level":2,"score":0.28999999165534973},{"id":"https://openalex.org/C142052008","wikidata":"https://www.wikidata.org/wiki/Q954027","display_name":"Cross-sectional study","level":2,"score":0.27549999952316284},{"id":"https://openalex.org/C2776178081","wikidata":"https://www.wikidata.org/wiki/Q3286546","display_name":"Respiratory disease","level":3,"score":0.2646999955177307},{"id":"https://openalex.org/C179755657","wikidata":"https://www.wikidata.org/wiki/Q58702","display_name":"Mortality rate","level":2,"score":0.2531999945640564},{"id":"https://openalex.org/C50382708","wikidata":"https://www.wikidata.org/wiki/Q223218","display_name":"Proportional hazards model","level":2,"score":0.2500999867916107}],"mesh":[{"descriptor_ui":"D000091482","descriptor_name":"Social Vulnerability","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000091542","descriptor_name":"Neighborhood Characteristics","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":true},{"descriptor_ui":"D000093862","descriptor_name":"Socioeconomic Disparities in Health","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009026","descriptor_name":"Mortality","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011788","descriptor_name":"Quality of Life","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012111","descriptor_name":"Residence Characteristics","qualifier_ui":"Q000706","qualifier_name":"statistics & numerical data","is_major_topic":true},{"descriptor_ui":"D012907","descriptor_name":"Smoking","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D014797","descriptor_name":"Vital Capacity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1001/jamanetworkopen.2026.42912","doi":"https://doi.org/10.1001/jamanetworkopen.2026.42912","is_oa":true,"landing_page_url":"https://doi.org/10.1001/jamanetworkopen.2026.42912","pdf_url":"https://jamanetwork.com/journals/jamanetworkopen/articlepdf/2856344/wu_2026_oi_261154_1793633566.67135.pdf","source":{"id":"https://openalex.org/S4210217848","display_name":"JAMA Network Open","issn_l":"2574-3805","issn":["2574-3805"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-2","medline","norway-1","oarl","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320259","host_organization_name":"American Medical Association","host_organization_lineage":["https://openalex.org/P4310320259"],"host_organization_lineage_names":["American Medical Association"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JAMA Network Open","raw_type":"journal-article"},{"id":"pmid:43002398","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/43002398","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JAMA network open","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1001/jamanetworkopen.2026.42912","doi":"https://doi.org/10.1001/jamanetworkopen.2026.42912","is_oa":true,"landing_page_url":"https://doi.org/10.1001/jamanetworkopen.2026.42912","pdf_url":"https://jamanetwork.com/journals/jamanetworkopen/articlepdf/2856344/wu_2026_oi_261154_1793633566.67135.pdf","source":{"id":"https://openalex.org/S4210217848","display_name":"JAMA Network Open","issn_l":"2574-3805","issn":["2574-3805"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-2","medline","norway-1","oarl","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320259","host_organization_name":"American Medical Association","host_organization_lineage":["https://openalex.org/P4310320259"],"host_organization_lineage_names":["American Medical Association"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JAMA Network Open","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0},{"id":"https://metadata.un.org/sdg/10","display_name":"Reduced inequalities","score":0.7307999730110168}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337353","display_name":"National Institute of Nursing Research","ror":"https://ror.org/01y3zfr79"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7225636287.pdf","grobid_xml":"https://content.openalex.org/works/W7225636287.grobid-xml"},"referenced_works_count":48,"referenced_works":["https://openalex.org/W1969043580","https://openalex.org/W1971801931","https://openalex.org/W1981266696","https://openalex.org/W2014327575","https://openalex.org/W2024970176","https://openalex.org/W2025508129","https://openalex.org/W2026132176","https://openalex.org/W2041568486","https://openalex.org/W2052977441","https://openalex.org/W2077385536","https://openalex.org/W2096099911","https://openalex.org/W2122797682","https://openalex.org/W2143982567","https://openalex.org/W2152174546","https://openalex.org/W2157898372","https://openalex.org/W2165794458","https://openalex.org/W2169302793","https://openalex.org/W2237927442","https://openalex.org/W2296611298","https://openalex.org/W2493459217","https://openalex.org/W2604596332","https://openalex.org/W2737288556","https://openalex.org/W2737658844","https://openalex.org/W2772915294","https://openalex.org/W2938704617","https://openalex.org/W2984453596","https://openalex.org/W3021620221","https://openalex.org/W3171615839","https://openalex.org/W3194401096","https://openalex.org/W3216004378","https://openalex.org/W4210678274","https://openalex.org/W4221091960","https://openalex.org/W4225250167","https://openalex.org/W4282003568","https://openalex.org/W4293004803","https://openalex.org/W4293813329","https://openalex.org/W4294943801","https://openalex.org/W4304974914","https://openalex.org/W4385410648","https://openalex.org/W4390479957","https://openalex.org/W4391089717","https://openalex.org/W4401231256","https://openalex.org/W4401391174","https://openalex.org/W4403837716","https://openalex.org/W4403901421","https://openalex.org/W4404506800","https://openalex.org/W4404755690","https://openalex.org/W4404941686"],"related_works":["https://openalex.org/W4410276562","https://openalex.org/W7154580974","https://openalex.org/W3100854023","https://openalex.org/W3157803699","https://openalex.org/W4396503370","https://openalex.org/W4367609516","https://openalex.org/W4304974914","https://openalex.org/W2116552906","https://openalex.org/W3097043849","https://openalex.org/W3196459074"],"abstract_inverted_index":{"Importance:":[0],"Neighborhood":[1],"social":[2],"disadvantage":[3],"(NSD)":[4],"is":[5],"increasingly":[6],"recognized":[7],"as":[8,201],"being":[9],"associated":[10,236,264,387],"with":[11,17,38,70,164,208,237,265,374,388,419],"health":[12,170,354],"disparities.":[13],"However,":[14],"its":[15],"associations":[16,35,205,349,373,416],"longitudinal":[18,136],"lung":[19,39,137,195,353,357,390,420],"function":[20,138,196,358,391,421],"decline,":[21,392],"health-related":[22],"quality":[23],"of":[24,36,50,60,75,206,347,371,417],"life":[25],"(HRQOL),":[26],"and":[27,42,45,55,62,121,132,135,150,172,178,190,197,225,249,279,306,319,336,352,359,378,395,409,422],"mortality":[28,44,309,398],"remain":[29],"incompletely":[30],"understood.":[31],"Objective:":[32],"To":[33],"evaluate":[34],"NSD":[37,207,351,385,418],"function,":[40],"HRQOL,":[41,293,394],"all-cause":[43,179,209,308,375,397],"to":[46,67,111,127,246,257,276,287,329,331,341,366],"explore":[47],"potential":[48,202],"mediators":[49,203],"any":[51],"association.":[52],"Design,":[53],"Setting,":[54],"Participants:":[56],"Prospective":[57],"cohort":[58,382],"study":[59],"current":[61,187,406],"former":[63],"smokers":[64],"aged":[65],"40":[66],"75":[68],"years":[69],"at":[71],"least":[72],"10":[73],"pack-years":[74],"smoking":[76,188,317,407],"history":[77],"in":[78,142,233,269],"the":[79,102,151,158,173,216],"Lovelace":[80],"Smokers":[81],"Cohort.":[82],"Participants":[83],"underwent":[84],"repeated":[85],"spirometry":[86],"approximately":[87],"every":[88],"18":[89],"months":[90],"from":[91,109],"2001":[92],"through":[93,98],"2017.":[94],"Mortality":[95],"was":[96,221,235,263,386],"ascertained":[97],"October":[99],"2020":[100],"using":[101],"National":[103],"Death":[104],"Index.":[105],"Data":[106],"were":[107,199,228],"analyzed":[108],"January":[110],"May":[112],"2025.":[113],"Exposures:":[114],"Census":[115],"tract-level":[116],"Social":[117,122],"Vulnerability":[118],"Index":[119,124],"(SVI)":[120],"Deprivation":[123],"(SDI)":[125],"assigned":[126],"residential":[128],"addresses.":[129],"Main":[130],"Outcomes":[131],"Measures:":[133],"Baseline":[134],"(forced":[139],"expiratory":[140],"volume":[141],"1":[143],"second":[144],"[FEV1],":[145],"forced":[146],"vital":[147],"capacity":[148],"[FVC],":[149],"FEV1:FVC":[152,250,280],"ratio),":[153],"baseline":[154,194,219,239,292,356],"HRQOL":[155,198,360],"assessed":[156],"by":[157],"St":[159],"George's":[160],"Respiratory":[161],"Questionnaire":[162],"(SGRQ),":[163],"higher":[165,296,307,396],"scores":[166,323],"indicating":[167],"poorer":[168],"respiratory":[169],"status,":[171,189],"36-item":[174],"Short":[175],"Form":[176],"Survey,":[177],"mortality.":[180,210,376],"Formal":[181],"mediation":[182],"analyses":[183,403],"evaluated":[184],"educational":[185],"attainment,":[186],"dietary":[191,321,410],"patterns,":[192],"whereas":[193],"considered":[200],"for":[204,415],"Results:":[211],"Among":[212],"2362":[213],"included":[214],"participants,":[215],"mean":[217],"(SD)":[218],"age":[220],"56.3":[222],"(9.4)":[223],"years,":[224],"1738":[226],"(73.58%)":[227],"female.":[229],"A":[230],"1-IQR":[231],"increase":[232],"SDI":[234],"lower":[238],"FEV1":[240,270],"(\u03b2,":[241,252,271,282,300],"-0.09":[242],"[95%":[243,254,273,284,302,313],"CI,":[244,255,274,285,303,314,327,334,339,344,364,369],"-0.13":[245],"-0.06]":[247],"L)":[248],"ratio":[251,281],"-1.21":[253],"-1.80":[256],"-0.62]":[258],"percentage":[259,289],"points).":[260],"Higher":[261],"SVI":[262],"faster":[266,389],"annual":[267],"decline":[268],"-3.11":[272],"-5.86":[275],"-0.36]":[277],"mL/y)":[278],"-0.05":[283],"-0.11":[286],"-0.001]":[288],"points/y),":[290],"worse":[291,384,393],"including":[294],"a":[295],"SGRQ":[297],"total":[298],"score":[299],"4.46":[301],"3.26-5.65]":[304],"points),":[305],"(hazard":[310],"ratio,":[311],"1.28":[312],"1.08-1.53]).":[315],"Current":[316],"status":[318,408],"2":[320],"pattern":[322],"mediated":[324,361],"4.4%":[325],"(95%":[326,333,338,343,363,368],"-1.2%":[328],"12.8%)":[330],"31.0%":[332],"13.0%-51.6%)":[335],"4.5%":[337],"0.2%-12.9%)":[340],"17.0%":[342],"5.5%-113.7%),":[345],"respectively,":[346],"selected":[348,372],"between":[350],"outcomes;":[355],"6.7%":[362],"0.6%-22.8%)":[365],"38.6%":[367],"19.9%-125.3%)":[370],"Conclusions":[377],"Relevance:":[379],"In":[380],"this":[381],"study,":[383],"among":[399],"ever":[400],"smokers.":[401],"Mediation":[402],"suggested":[404],"that":[405],"patterns":[411],"may":[412],"partially":[413],"account":[414],"HRQOL.":[423]},"counts_by_year":[],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2026-11-10T00:00:00"}