{"id":"https://openalex.org/W7225627707","doi":"https://doi.org/10.1007/s00467-026-07628-5","title":"PODIUM renal dysfunction criteria identify children with higher severity of illness than KDIGO acute kidney injury criteria in an observational cohort study","display_name":"PODIUM renal dysfunction criteria identify children with higher severity of illness than KDIGO acute kidney injury criteria in an observational cohort study","publication_year":2026,"publication_date":"2026-11-09","ids":{"openalex":"https://openalex.org/W7225627707","doi":"https://doi.org/10.1007/s00467-026-07628-5","pmid":"https://pubmed.ncbi.nlm.nih.gov/43002226"},"language":"en","primary_location":{"id":"doi:10.1007/s00467-026-07628-5","doi":"https://doi.org/10.1007/s00467-026-07628-5","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00467-026-07628-5","pdf_url":"https://link.springer.com/content/pdf/10.1007/s00467-026-07628-5.pdf","source":{"id":"https://openalex.org/S25178087","display_name":"Pediatric Nephrology","issn_l":"0931-041X","issn":["0931-041X","1432-198X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatric Nephrology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://link.springer.com/content/pdf/10.1007/s00467-026-07628-5.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5024876124","display_name":"Celeste Dixon","orcid":"https://orcid.org/0000-0003-1175-2235","observed_orcids":["https://orcid.org/0000-0003-1175-2235"]},"institutions":[{"id":"https://openalex.org/I1335321130","display_name":"Children's Hospital of Philadelphia","ror":"https://ror.org/01z7r7q48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1335321130"]},{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Celeste G. Dixon","raw_affiliation_strings":["Division of Critical Care Medicine, Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA. dixonc5@chop.edu"],"raw_orcid":"https://orcid.org/0000-0003-1175-2235","affiliations":[{"raw_affiliation_string":"Division of Critical Care Medicine, Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA. dixonc5@chop.edu","institution_ids":["https://openalex.org/I1335321130","https://openalex.org/I79576946"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045860232","display_name":"Veronica Kirchner","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1335321130","display_name":"Children's Hospital of Philadelphia","ror":"https://ror.org/01z7r7q48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1335321130"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Veronica Kirchner","raw_affiliation_strings":["Center for Healthcare Quality and Analytics, Children's Hospital of Philadelphia, Philadelphia, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Healthcare Quality and Analytics, Children's Hospital of Philadelphia, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I1335321130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031613696","display_name":"Nadir Yehya","orcid":"https://orcid.org/0000-0002-2996-217X","observed_orcids":["https://orcid.org/0000-0002-2996-217X"]},"institutions":[{"id":"https://openalex.org/I1335321130","display_name":"Children's Hospital of Philadelphia","ror":"https://ror.org/01z7r7q48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1335321130"]},{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nadir Yehya","raw_affiliation_strings":["Division of Critical Care Medicine, Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Critical Care Medicine, Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I1335321130","https://openalex.org/I79576946"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5074414483","display_name":"Julie C. Fitzgerald","orcid":"https://orcid.org/0000-0002-7627-1689","observed_orcids":["https://orcid.org/0000-0002-7627-1689"]},"institutions":[{"id":"https://openalex.org/I1335321130","display_name":"Children's Hospital of Philadelphia","ror":"https://ror.org/01z7r7q48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1335321130"]},{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Julie C. Fitzgerald","raw_affiliation_strings":["Division of Critical Care Medicine, Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Critical Care Medicine, Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA","institution_ids":["https://openalex.org/I1335321130","https://openalex.org/I79576946"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5024876124"],"corresponding_institution_ids":["https://openalex.org/I1335321130","https://openalex.org/I79576946"],"apc_list":{"value":4337,"currency":"USD","value_usd":4337},"apc_paid":{"value":4337,"currency":"USD","value_usd":4337},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10684","display_name":"Acute Kidney Injury Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10684","display_name":"Acute Kidney Injury Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10218","display_name":"Sepsis Diagnosis and Treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acute-kidney-injury","display_name":"acute kidney injury","score":0.7929999828338623},{"id":"https://openalex.org/keywords/pediatric-intensive-care","display_name":"pediatric intensive care","score":0.7229999899864197},{"id":"https://openalex.org/keywords/fluid-overload","display_name":"fluid overload","score":0.8709999918937683},{"id":"https://openalex.org/keywords/renal-dysfunction","display_name":"renal dysfunction","score":0.6629999876022339},{"id":"https://openalex.org/keywords/aki-severity","display_name":"AKI severity","score":0.621999979019165},{"id":"https://openalex.org/keywords/mortality","display_name":"mortality","score":0.718999981880188},{"id":"https://openalex.org/keywords/picu-length-of-stay","display_name":"PICU length of stay","score":0.9120000004768372},{"id":"https://openalex.org/keywords/major-adverse-kidney-events","display_name":"major adverse kidney events","score":0.953000009059906},{"id":"https://openalex.org/keywords/critically-ill-children","display_name":"critically ill children","score":0.921999990940094},{"id":"https://openalex.org/keywords/diagnostic-criteria-comparison","display_name":"diagnostic criteria comparison","score":0.5630000233650208},{"id":"https://openalex.org/keywords/urine-output","display_name":"urine output","score":0.699999988079071},{"id":"https://openalex.org/keywords/fluid-balance","display_name":"fluid balance","score":0.7940000295639038},{"id":"https://openalex.org/keywords/creatinine","display_name":"creatinine","score":0.7089999914169312},{"id":"https://openalex.org/keywords/weight-gain","display_name":"weight gain","score":0.3109999895095825}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9587000012397766},{"id":"https://openalex.org/C2780472472","wikidata":"https://www.wikidata.org/wiki/Q424337","display_name":"Acute kidney injury","level":2,"score":0.8378999829292297},{"id":"https://openalex.org/C2778653478","wikidata":"https://www.wikidata.org/wiki/Q1054718","display_name":"Kidney disease","level":2,"score":0.6251000165939331},{"id":"https://openalex.org/C54847362","wikidata":"https://www.wikidata.org/wiki/Q177635","display_name":"Nephrology","level":2,"score":0.4478999972343445},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.42179998755455017},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.4101000130176544},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.3968000113964081},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.39559999108314514},{"id":"https://openalex.org/C2776376669","wikidata":"https://www.wikidata.org/wiki/Q5094647","display_name":"Intensive care unit","level":2,"score":0.39430001378059387},{"id":"https://openalex.org/C30036603","wikidata":"https://www.wikidata.org/wiki/Q17125150","display_name":"Severity of illness","level":2,"score":0.3224000036716461},{"id":"https://openalex.org/C2991859549","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Critically ill","level":2,"score":0.321399986743927},{"id":"https://openalex.org/C194828623","wikidata":"https://www.wikidata.org/wiki/Q2861470","display_name":"Emergency medicine","level":1,"score":0.2953999936580658},{"id":"https://openalex.org/C2779541074","wikidata":"https://www.wikidata.org/wiki/Q185643","display_name":"Renal replacement therapy","level":2,"score":0.29499998688697815},{"id":"https://openalex.org/C2987404301","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care","level":2,"score":0.26930001378059387},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.26759999990463257},{"id":"https://openalex.org/C23131810","wikidata":"https://www.wikidata.org/wiki/Q818574","display_name":"Observational study","level":2,"score":0.2596000134944916},{"id":"https://openalex.org/C2993568657","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Critical illness","level":3,"score":0.25699999928474426}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1007/s00467-026-07628-5","doi":"https://doi.org/10.1007/s00467-026-07628-5","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00467-026-07628-5","pdf_url":"https://link.springer.com/content/pdf/10.1007/s00467-026-07628-5.pdf","source":{"id":"https://openalex.org/S25178087","display_name":"Pediatric Nephrology","issn_l":"0931-041X","issn":["0931-041X","1432-198X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatric Nephrology","raw_type":"journal-article"},{"id":"pmid:43002226","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/43002226","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatric nephrology (Berlin, Germany)","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1007/s00467-026-07628-5","doi":"https://doi.org/10.1007/s00467-026-07628-5","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00467-026-07628-5","pdf_url":"https://link.springer.com/content/pdf/10.1007/s00467-026-07628-5.pdf","source":{"id":"https://openalex.org/S25178087","display_name":"Pediatric Nephrology","issn_l":"0931-041X","issn":["0931-041X","1432-198X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatric Nephrology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7225627707.pdf","grobid_xml":"https://content.openalex.org/works/W7225627707.grobid-xml"},"referenced_works_count":21,"referenced_works":["https://openalex.org/W1967300023","https://openalex.org/W1973914566","https://openalex.org/W1989028027","https://openalex.org/W2007813089","https://openalex.org/W2060817703","https://openalex.org/W2065951290","https://openalex.org/W2084445380","https://openalex.org/W2098441893","https://openalex.org/W2139937737","https://openalex.org/W2140796490","https://openalex.org/W2153844295","https://openalex.org/W2161086083","https://openalex.org/W2334367545","https://openalex.org/W2550172802","https://openalex.org/W2615505548","https://openalex.org/W2912902612","https://openalex.org/W2952762910","https://openalex.org/W3135720188","https://openalex.org/W3181966412","https://openalex.org/W4206119689","https://openalex.org/W4327895871"],"related_works":["https://openalex.org/W4416768024","https://openalex.org/W2153844295","https://openalex.org/W3165090465","https://openalex.org/W3119462742","https://openalex.org/W3048795843","https://openalex.org/W4389764316","https://openalex.org/W4406213699","https://openalex.org/W7224034898","https://openalex.org/W2806288730","https://openalex.org/W4388033707"],"abstract_inverted_index":{"BACKGROUND:":[0],"KDIGO":[1,38,94,124,129,133,138,148,156,162,181,204,229,235,258],"acute":[2],"kidney":[3,111],"injury":[4],"(AKI)":[5],"criteria":[6,21,226,239,259],"are":[7],"not":[8,28,57,221],"specific":[9],"to":[10],"children.":[11],"Pediatric":[12],"Organ":[13],"Dysfunction":[14],"Information":[15],"Update":[16],"Mandate":[17],"(PODIUM)":[18],"renal":[19,33],"dysfunction":[20,34],"were":[22,84,90,101,178],"developed":[23],"for":[24,242],"children":[25,246],"but":[26,220],"have":[27],"been":[29,58],"adopted.":[30],"PODIUM":[31,98,159,171,184,196,225,238],"defines":[32],"more":[35],"strictly":[36],"than":[37,203],"and":[39,82,97,108,135,151,183],"adds":[40],"fluid":[41,80],"overload":[42],"(FO)":[43],"as":[44],"an":[45,71],"independent":[46],"criterion.":[47,176],"The":[48],"impact":[49],"of":[50,63,105,168,264],"these":[51],"changes":[52],"on":[53],"AKI":[54,95,125,157,172,185,209,250,265],"diagnosis":[55],"has":[56],"evaluated.":[59],"METHODS:":[60],"Retrospective":[61],"analysis":[62],"pediatric":[64],"intensive":[65],"care":[66],"unit":[67],"(PICU)":[68],"admissions":[69],"at":[70,113],"academic":[72],"children's":[73],"hospital":[74],"from":[75],"06/2022-05/2025.":[76],"Creatinine,":[77],"urine":[78],"output,":[79],"balance,":[81],"weight":[83],"extracted":[85],"in":[86,252],"6-h":[87],"intervals.":[88],"Patients":[89,194],"classified":[91],"by":[92,197],"maximum":[93],"stage":[96],"AKI.":[99],"Outcomes":[100,177],"mortality,":[102],"PICU":[103],"length":[104],"stay":[106],"(LOS),":[107],"major":[109],"adverse":[110],"events":[112],"30":[114],"days":[115],"(MAKE-30).":[116],"RESULTS:":[117],"In":[118],"10,454":[119],"patients,":[120],"2,602":[121],"(25%)":[122],"met":[123,144,158,164,173],"criteria:":[126],"1,124":[127],"(11%)":[128],"1,":[130],"579":[131],"(5%)":[132],"2,":[134],"899":[136],"(9%)":[137,147],"3.":[139],"By":[140],"PODIUM,":[141],"1,599":[142],"(15%)":[143],"criteria.":[145],"105":[146],"1":[149,206,236],"patients":[150,154,169,231],"16":[152],"(0.2%)":[153],"without":[155],"criteria;":[160],"all":[161,228],"2/3":[163,182,230],"PODIUM.":[165],"110/1,599":[166],"(7%)":[167],"with":[170,247],"only":[174],"FO":[175,198],"similar":[179],"between":[180],"(mortality":[186,210],"6-7%,":[187],"median":[188,214],"LOS":[189,215],"7-8.5":[190],"days,":[191],"MAKE-30":[192],"12%).":[193],"meeting":[195],"alone":[199],"had":[200],"worse":[201],"outcomes":[202],"Stage":[205],"or":[207],"No":[208],"4%":[211],"vs.":[212,217],"1-2%,":[213],"13.8":[216],"1.5-5.5":[218],"days),":[219],"different":[222],"MAKE-30.":[223],"CONCLUSIONS:":[224],"capture":[227,260],"while":[232,257],"excluding":[233],"most":[234],"patients.":[237],"appear":[240],"useful":[241],"identifying":[243],"critically":[244],"ill":[245],"clinically":[248],"significant":[249],"resulting":[251],"greater":[253],"short-term":[254],"illness":[255],"severity,":[256],"a":[261],"larger":[262],"spectrum":[263],"severity.":[266]},"counts_by_year":[],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2026-11-10T00:00:00"}