{"id":"https://openalex.org/W7225626183","doi":"https://doi.org/10.1007/s13205-026-05127-w","title":"Therapeutic potential of herbal topical agents in evidence-based wound care: a systematic research review","display_name":"Therapeutic potential of herbal topical agents in evidence-based wound care: a systematic research review","publication_year":2026,"publication_date":"2026-11-09","ids":{"openalex":"https://openalex.org/W7225626183","doi":"https://doi.org/10.1007/s13205-026-05127-w"},"language":"en","primary_location":{"id":"doi:10.1007/s13205-026-05127-w","doi":"https://doi.org/10.1007/s13205-026-05127-w","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s13205-026-05127-w","pdf_url":"https://link.springer.com/content/pdf/10.1007/s13205-026-05127-w.pdf","source":{"id":"https://openalex.org/S4210190239","display_name":"3 Biotech","issn_l":"2190-572X","issn":["2190-572X","2190-5738"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"3 Biotech","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://link.springer.com/content/pdf/10.1007/s13205-026-05127-w.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5055636806","display_name":"Rasna Kumari","orcid":"https://orcid.org/0009-0005-4911-2083","observed_orcids":["https://orcid.org/0009-0005-4911-2083"]},"institutions":[{"id":"https://openalex.org/I4210133503","display_name":"Central University of Haryana","ror":"https://ror.org/03mtwkv54","country_code":"IN","type":"education","lineage":["https://openalex.org/I4210133503"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Rasna Kumari","raw_affiliation_strings":["Department of Pharmaceutical Sciences, Central University of Haryana, Mahendergarh, Haryana, 123031, India"],"raw_orcid":"https://orcid.org/0009-0005-4911-2083","affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical Sciences, Central University of Haryana, Mahendergarh, Haryana, 123031, India","institution_ids":["https://openalex.org/I4210133503"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086264802","display_name":"Tarun Kumar","orcid":"https://orcid.org/0000-0002-5450-1586","observed_orcids":["https://orcid.org/0000-0002-5450-1586"]},"institutions":[{"id":"https://openalex.org/I4210133503","display_name":"Central University of Haryana","ror":"https://ror.org/03mtwkv54","country_code":"IN","type":"education","lineage":["https://openalex.org/I4210133503"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Tarun Kumar","raw_affiliation_strings":["Department of Pharmaceutical Sciences, Central University of Haryana, Mahendergarh, Haryana, 123031, India"],"raw_orcid":"https://orcid.org/0000-0002-5450-1586","affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical Sciences, Central University of Haryana, Mahendergarh, Haryana, 123031, India","institution_ids":["https://openalex.org/I4210133503"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015103250","display_name":"Shriram Pandey","orcid":"https://orcid.org/0000-0002-1690-6603","observed_orcids":["https://orcid.org/0000-0002-1690-6603"]},"institutions":[{"id":"https://openalex.org/I4210133503","display_name":"Central University of Haryana","ror":"https://ror.org/03mtwkv54","country_code":"IN","type":"education","lineage":["https://openalex.org/I4210133503"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Shriram Pandey","raw_affiliation_strings":["Department of Library and Information Science, Central University of Haryana, Mahendergarh, 123031, India"],"raw_orcid":"https://orcid.org/0000-0002-1690-6603","affiliations":[{"raw_affiliation_string":"Department of Library and Information Science, Central University of Haryana, Mahendergarh, 123031, India","institution_ids":["https://openalex.org/I4210133503"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058751417","display_name":"Neha Jain","orcid":"https://orcid.org/0000-0003-3827-5598","observed_orcids":["https://orcid.org/0000-0003-3827-5598","https://orcid.org/0009-0009-3887-9077"]},"institutions":[{"id":"https://openalex.org/I191972202","display_name":"Amity University","ror":"https://ror.org/02n9z0v62","country_code":"IN","type":"education","lineage":["https://openalex.org/I191972202"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Neha Jain","raw_affiliation_strings":["Department of Pharmaceutics, Amity Institute of Pharmacy, Amity University, Noida, India"],"raw_orcid":"https://orcid.org/0000-0003-3827-5598","affiliations":[{"raw_affiliation_string":"Department of Pharmaceutics, Amity Institute of Pharmacy, Amity University, Noida, India","institution_ids":["https://openalex.org/I191972202"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003874983","display_name":"Manisha Pandey","orcid":"https://orcid.org/0000-0002-8249-9743","observed_orcids":["https://orcid.org/0000-0002-8249-9743"]},"institutions":[{"id":"https://openalex.org/I4210133503","display_name":"Central University of Haryana","ror":"https://ror.org/03mtwkv54","country_code":"IN","type":"education","lineage":["https://openalex.org/I4210133503"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Manisha Pandey","raw_affiliation_strings":["Department of Pharmaceutical Sciences, Central University of Haryana, Mahendergarh, Haryana, 123031, India"],"raw_orcid":"https://orcid.org/0000-0002-8249-9743","affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical Sciences, Central University of Haryana, Mahendergarh, Haryana, 123031, India","institution_ids":["https://openalex.org/I4210133503"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085773686","display_name":"Najwa Mohamad","orcid":"https://orcid.org/0000-0003-0276-8817","observed_orcids":["https://orcid.org/0000-0003-0276-8817"]},"institutions":[{"id":"https://openalex.org/I2802910988","display_name":"University of Cyberjaya","ror":"https://ror.org/04f1eek20","country_code":"MY","type":"education","lineage":["https://openalex.org/I2802910988"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Najwa Mohamad","raw_affiliation_strings":["Department of Pharmaceutical Technology and industry, Faculty of Pharmacy, University of Cyberjaya, Persiaran Bestari, 63000, Cyberjaya, Selangor Darul Ehsan, Malaysia"],"raw_orcid":"https://orcid.org/0000-0003-0276-8817","affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical Technology and industry, Faculty of Pharmacy, University of Cyberjaya, Persiaran Bestari, 63000, Cyberjaya, Selangor Darul Ehsan, Malaysia","institution_ids":["https://openalex.org/I2802910988"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024696868","display_name":"Mohd Cairul Iqbal Mohd Amin","orcid":"https://orcid.org/0000-0001-7394-1328","observed_orcids":["https://orcid.org/0000-0001-7394-1328"]},"institutions":[{"id":"https://openalex.org/I885383172","display_name":"National University of Malaysia","ror":"https://ror.org/00bw8d226","country_code":"MY","type":"education","lineage":["https://openalex.org/I885383172"]}],"countries":["MY"],"is_corresponding":false,"raw_author_name":"Mohd Cairul Iqbal Mohd Amin","raw_affiliation_strings":["Centre for Drug Delivery Technology & Vaccine, Faculty of Pharmacy, University Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, Kuala Lumpur, Malaysia"],"raw_orcid":"https://orcid.org/0000-0001-7394-1328","affiliations":[{"raw_affiliation_string":"Centre for Drug Delivery Technology & Vaccine, Faculty of Pharmacy, University Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, Kuala Lumpur, Malaysia","institution_ids":["https://openalex.org/I885383172"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100755840","display_name":"Pradeep Kumar","orcid":"https://orcid.org/0000-0002-8640-4350","observed_orcids":["https://orcid.org/0000-0002-8640-4350","https://orcid.org/0000-0003-4125-1191"]},"institutions":[{"id":"https://openalex.org/I192619145","display_name":"University of the Witwatersrand","ror":"https://ror.org/03rp50x72","country_code":"ZA","type":"education","lineage":["https://openalex.org/I192619145"]}],"countries":["ZA"],"is_corresponding":true,"raw_author_name":"Pradeep Kumar","raw_affiliation_strings":["Wits Advanced Drug Delivery Platform Research Unit, Department of Pharmacy and Pharmacology, School of Therapeutic Sciences, Faculty of Health Sciences, University of the Witwatersrand, 7 York Road, Parktown, Johannesburg, 2193, South Africa"],"raw_orcid":"https://orcid.org/0000-0002-8640-4350","affiliations":[{"raw_affiliation_string":"Wits Advanced Drug Delivery Platform Research Unit, Department of Pharmacy and Pharmacology, School of Therapeutic Sciences, Faculty of Health Sciences, University of the Witwatersrand, 7 York Road, Parktown, Johannesburg, 2193, South Africa","institution_ids":["https://openalex.org/I192619145"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5003874983","https://openalex.org/A5058751417","https://openalex.org/A5100755840"],"corresponding_institution_ids":["https://openalex.org/I191972202","https://openalex.org/I192619145","https://openalex.org/I4210133503"],"apc_list":{"value":4090,"currency":"USD","value_usd":4090},"apc_paid":{"value":4090,"currency":"USD","value_usd":4090},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"16","issue":"12","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10771","display_name":"Wound Healing and Treatments","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10771","display_name":"Wound Healing and Treatments","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12346","display_name":"Phytochemistry and biological activity of medicinal plants","score":0.0019000000320374966,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/wound-infection","display_name":"wound infection","score":0.8029999732971191},{"id":"https://openalex.org/keywords/wound-healing","display_name":"wound healing","score":0.8080000281333923},{"id":"https://openalex.org/keywords/phytochemical-constituents","display_name":"phytochemical constituents","score":0.8600000143051147},{"id":"https://openalex.org/keywords/plant-extracts","display_name":"plant extracts","score":0.5329999923706055},{"id":"https://openalex.org/keywords/chronic-wounds","display_name":"chronic wounds","score":0.6740000247955322},{"id":"https://openalex.org/keywords/biofilm","display_name":"biofilm","score":0.7940000295639038},{"id":"https://openalex.org/keywords/antimicrobial-activity","display_name":"antimicrobial activity","score":0.8550000190734863},{"id":"https://openalex.org/keywords/antioxidant-activity","display_name":"antioxidant activity","score":0.7490000128746033},{"id":"https://openalex.org/keywords/anti-inflammatory-activity","display_name":"anti-inflammatory activity","score":0.9860000014305115},{"id":"https://openalex.org/keywords/angiogenesis","display_name":"angiogenesis","score":0.9860000014305115},{"id":"https://openalex.org/keywords/re-epithelialization","display_name":"re-epithelialization","score":0.9020000100135803},{"id":"https://openalex.org/keywords/collagen-deposition","display_name":"collagen deposition","score":0.6830000281333923},{"id":"https://openalex.org/keywords/wound-dressings","display_name":"wound dressings","score":0.546999990940094},{"id":"https://openalex.org/keywords/safety-assessment","display_name":"safety assessment","score":0.3970000147819519}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8959000110626221},{"id":"https://openalex.org/C189708586","wikidata":"https://www.wikidata.org/wiki/Q1504425","display_name":"Systematic review","level":3,"score":0.6341000199317932},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.60589998960495},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.566100001335144},{"id":"https://openalex.org/C4937899","wikidata":"https://www.wikidata.org/wiki/Q68541106","display_name":"Antimicrobial","level":2,"score":0.4984999895095825},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.49160000681877136},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.46140000224113464},{"id":"https://openalex.org/C195475562","wikidata":"https://www.wikidata.org/wiki/Q1639139","display_name":"Phytochemical","level":2,"score":0.41110000014305115},{"id":"https://openalex.org/C2777466982","wikidata":"https://www.wikidata.org/wiki/Q5227287","display_name":"Data extraction","level":3,"score":0.376800000667572},{"id":"https://openalex.org/C27415008","wikidata":"https://www.wikidata.org/wiki/Q7256382","display_name":"Psychological intervention","level":2,"score":0.36039999127388},{"id":"https://openalex.org/C502991105","wikidata":"https://www.wikidata.org/wiki/Q5133849","display_name":"Clinical research","level":2,"score":0.33739998936653137},{"id":"https://openalex.org/C2779969877","wikidata":"https://www.wikidata.org/wiki/Q861699","display_name":"Phytotherapy","level":3,"score":0.33629998564720154},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3334999978542328},{"id":"https://openalex.org/C19648533","wikidata":"https://www.wikidata.org/wiki/Q691640","display_name":"Evidence-based medicine","level":3,"score":0.33079999685287476},{"id":"https://openalex.org/C63363279","wikidata":"https://www.wikidata.org/wiki/Q5133848","display_name":"Clinical significance","level":2,"score":0.328900009393692},{"id":"https://openalex.org/C148482608","wikidata":"https://www.wikidata.org/wiki/Q17007018","display_name":"Clinical study design","level":3,"score":0.3285999894142151},{"id":"https://openalex.org/C3020322424","wikidata":"https://www.wikidata.org/wiki/Q1259977","display_name":"Herbal extracts","level":2,"score":0.32199999690055847},{"id":"https://openalex.org/C2992053201","wikidata":"https://www.wikidata.org/wiki/Q2585693","display_name":"Clinical efficacy","level":2,"score":0.30559998750686646},{"id":"https://openalex.org/C2780269544","wikidata":"https://www.wikidata.org/wiki/Q1509074","display_name":"Wound healing","level":2,"score":0.29670000076293945},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.28790000081062317},{"id":"https://openalex.org/C3018263421","wikidata":"https://www.wikidata.org/wiki/Q80083","display_name":"Human studies","level":2,"score":0.2863999903202057},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.27649998664855957},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.26159998774528503}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/s13205-026-05127-w","doi":"https://doi.org/10.1007/s13205-026-05127-w","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s13205-026-05127-w","pdf_url":"https://link.springer.com/content/pdf/10.1007/s13205-026-05127-w.pdf","source":{"id":"https://openalex.org/S4210190239","display_name":"3 Biotech","issn_l":"2190-572X","issn":["2190-572X","2190-5738"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"3 Biotech","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1007/s13205-026-05127-w","doi":"https://doi.org/10.1007/s13205-026-05127-w","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s13205-026-05127-w","pdf_url":"https://link.springer.com/content/pdf/10.1007/s13205-026-05127-w.pdf","source":{"id":"https://openalex.org/S4210190239","display_name":"3 Biotech","issn_l":"2190-572X","issn":["2190-572X","2190-5738"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"3 Biotech","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.979200005531311,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/systematic-review","display_name":"Systematic Review"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7225626183.pdf","grobid_xml":"https://content.openalex.org/works/W7225626183.grobid-xml"},"referenced_works_count":86,"referenced_works":["https://openalex.org/W1894458400","https://openalex.org/W1977958471","https://openalex.org/W1998900012","https://openalex.org/W2022862574","https://openalex.org/W2051404846","https://openalex.org/W2074498845","https://openalex.org/W2076515304","https://openalex.org/W2079986831","https://openalex.org/W2104802836","https://openalex.org/W2129128705","https://openalex.org/W2339531152","https://openalex.org/W2566399670","https://openalex.org/W2600213386","https://openalex.org/W2774115008","https://openalex.org/W2790548503","https://openalex.org/W2793804500","https://openalex.org/W2886350511","https://openalex.org/W2891844341","https://openalex.org/W2895509357","https://openalex.org/W2949291570","https://openalex.org/W2961562537","https://openalex.org/W2968981980","https://openalex.org/W2981289315","https://openalex.org/W2999734186","https://openalex.org/W3003122423","https://openalex.org/W3118615836","https://openalex.org/W3119952098","https://openalex.org/W3141271786","https://openalex.org/W3196662301","https://openalex.org/W3205278338","https://openalex.org/W4210895055","https://openalex.org/W4225515007","https://openalex.org/W4280606056","https://openalex.org/W4284977351","https://openalex.org/W4297912715","https://openalex.org/W4313890454","https://openalex.org/W4360811612","https://openalex.org/W4360854436","https://openalex.org/W4366602224","https://openalex.org/W4366989501","https://openalex.org/W4367320491","https://openalex.org/W4377019682","https://openalex.org/W4382655400","https://openalex.org/W4385423245","https://openalex.org/W4386703849","https://openalex.org/W4388486969","https://openalex.org/W4389977011","https://openalex.org/W4390583179","https://openalex.org/W4390752969","https://openalex.org/W4391995997","https://openalex.org/W4392639384","https://openalex.org/W4393144087","https://openalex.org/W4394721789","https://openalex.org/W4394963705","https://openalex.org/W4395674070","https://openalex.org/W4396835792","https://openalex.org/W4396960895","https://openalex.org/W4401199840","https://openalex.org/W4401371927","https://openalex.org/W4401480932","https://openalex.org/W4401535069","https://openalex.org/W4401990211","https://openalex.org/W4402513202","https://openalex.org/W4404556537","https://openalex.org/W4405124517","https://openalex.org/W4405455495","https://openalex.org/W4405842240","https://openalex.org/W4405861772","https://openalex.org/W4405888540","https://openalex.org/W4405993848","https://openalex.org/W4406284848","https://openalex.org/W4407253277","https://openalex.org/W4408421894","https://openalex.org/W4408807813","https://openalex.org/W4408847709","https://openalex.org/W4409638745","https://openalex.org/W4411262280","https://openalex.org/W4412151323","https://openalex.org/W4412473800","https://openalex.org/W4412555232","https://openalex.org/W4412720117","https://openalex.org/W4414679517","https://openalex.org/W4415778161","https://openalex.org/W4417528402","https://openalex.org/W7160230649","https://openalex.org/W7203600528"],"related_works":["https://openalex.org/W7109044578","https://openalex.org/W4405888540","https://openalex.org/W6949435762","https://openalex.org/W7104266336","https://openalex.org/W2985653283","https://openalex.org/W3027392317","https://openalex.org/W7224204611","https://openalex.org/W4390875715","https://openalex.org/W7125245166","https://openalex.org/W7154025623"],"abstract_inverted_index":{"Abstract":[0],"Herbal":[1,211],"interventions":[2,131],"are":[3,250],"increasingly":[4],"investigated":[5],"for":[6,13,65,81,172,218,252],"wound":[7,82,111,138,163,220,256],"infection":[8],"due":[9],"to":[10,29,205],"their":[11,23,202,228],"potential":[12,216],"antimicrobial,":[14],"antioxidant,":[15],"anti-inflammatory,":[16],"tissue-repair":[17],"and":[18,40,58,88,93,115,117,121,150,165,178,198,213,245],"angiogenic":[19],"activities.":[20],"Despite":[21],"this,":[22,102],"clinical":[24,89,185,248],"relevance":[25],"is":[26],"uncertain":[27],"owing":[28],"substantial":[30,154],"heterogeneity":[31,155],"in":[32,49,63,137,156],"botanical":[33,105],"materials,":[34],"phytochemical":[35],"composition,":[36],"formulations,":[37,80,162,237],"experimental":[38],"models":[39],"level":[41],"of":[42,231],"evidence.":[43,99,192],"This":[44],"systematic":[45],"review":[46],"was":[47,60,181],"conducted":[48],"accordance":[50],"with":[51],"PRISMA":[52],"2020.":[53],"Literature":[54],"published":[55],"between":[56],"2000":[57],"2025":[59],"systematically":[61],"searched":[62],"PubMed":[64],"original":[66],"peer-reviewed":[67],"studies":[68,90],"evaluating":[69],"herbal":[70,130],"extracts":[71,212],"or":[72,76],"purified":[73],"phytoconstituents,":[74],"alone":[75],"incorporated":[77],"into":[78,254],"topical":[79,219],"infection.":[83],"In":[84],"vitro,":[85],"animal,":[86],"observational,":[87],"were":[91,123],"included":[92],"critically":[94],"interpreted":[95],"as":[96],"per":[97],"the":[98],"Other":[100],"than":[101,190],"data":[103],"on":[104],"authentication,":[106],"extraction,":[107],"standardization,":[108],"bioactive":[109],"constituents,":[110],"type,":[112],"formulation":[113],"characteristics,":[114],"antimicrobial":[116],"antifilm":[118],"activity,":[119,146],"efficacy":[120,207],"safety":[122,239],"extracted.":[124],"The":[125],"evidence":[126,186,224],"indicated":[127],"that":[128],"selected":[129],"can":[132],"modulate":[133],"multiple":[134],"processes":[135],"involved":[136],"repair,":[139],"including":[140],"inflammation,":[141],"oxidative":[142],"stress,":[143],"angiogenesis,":[144],"fibroblast":[145],"collagen":[147],"deposition,":[148],"re-epithelialization,":[149],"microbial":[151],"growth.":[152],"Nevertheless,":[153],"plant":[157],"sources,":[158],"extraction":[159],"methods,":[160],"concentrations,":[161],"models,":[164,244],"outcome":[166],"measures":[167],"limited":[168],"direct":[169],"comparison.":[170],"Evidence":[171],"activity":[173],"against":[174],"clinically":[175,241],"relevant":[176,242],"biofilms":[177],"chronic":[179],"wounds":[180],"comparatively":[182],"limited,":[183],"while":[184],"remained":[187],"less":[188],"extensive":[189],"preclinical":[191],"Advanced":[193],"formulations":[194],"may":[195],"improve":[196],"delivery":[197],"wound-site":[199],"retention,":[200],"although":[201],"independent":[203],"contribution":[204],"therapeutic":[206],"requires":[208],"further":[209],"clarification.":[210],"phytoconstituents":[214],"represent":[215],"candidates":[217],"management;":[221],"however,":[222],"current":[223],"does":[225],"not":[226],"support":[227],"routine":[229],"replacement":[230],"established":[232],"therapies.":[233],"Standardized":[234],"preparations,":[235],"reproducible":[236],"rigorous":[238],"evaluation,":[240],"chronic-wound":[243],"adequately":[246],"powered":[247],"trials":[249],"required":[251],"translation":[253],"evidence-based":[255],"care.":[257]},"counts_by_year":[],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2026-11-10T00:00:00"}
