{"id":"https://openalex.org/W7225625604","doi":"https://doi.org/10.1002/admt.71464","title":"Microneedles Fabrication by Substrate\u2010Independent Electrostretching and In\u2010Situ Focused Electrospray Deposition for Transdermal Drug Delivery","display_name":"Microneedles Fabrication by Substrate\u2010Independent Electrostretching and In\u2010Situ Focused Electrospray Deposition for Transdermal Drug Delivery","publication_year":2026,"publication_date":"2026-11-08","ids":{"openalex":"https://openalex.org/W7225625604","doi":"https://doi.org/10.1002/admt.71464"},"language":"en","primary_location":{"id":"doi:10.1002/admt.71464","doi":"https://doi.org/10.1002/admt.71464","is_oa":true,"landing_page_url":"https://doi.org/10.1002/admt.71464","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/admt.71464","source":{"id":"https://openalex.org/S2765038284","display_name":"Advanced Materials Technologies","issn_l":"2365-709X","issn":["2365-709X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advanced Materials Technologies","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/admt.71464","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5071015557","display_name":"Ngoc Luan","orcid":"https://orcid.org/0000-0003-2296-2254","observed_orcids":["https://orcid.org/0000-0003-2296-2254"]},"institutions":[{"id":"https://openalex.org/I11701301","display_name":"Griffith University","ror":"https://ror.org/02sc3r913","country_code":"AU","type":"education","lineage":["https://openalex.org/I11701301"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Ngoc Luan Mai","raw_affiliation_strings":["School of Engineering and Built Environment Griffith University  Southport Queensland Australia"],"raw_orcid":"https://orcid.org/0000-0003-2296-2254","affiliations":[{"raw_affiliation_string":"School of Engineering and Built Environment Griffith University  Southport Queensland Australia","institution_ids":["https://openalex.org/I11701301"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076434424","display_name":"Dinh Nghi Ngo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I11701301","display_name":"Griffith University","ror":"https://ror.org/02sc3r913","country_code":"AU","type":"education","lineage":["https://openalex.org/I11701301"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Dinh Nghi Ngo","raw_affiliation_strings":["School of Medicine and Dentistry Griffith University  Southport Queensland Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Medicine and Dentistry Griffith University  Southport Queensland Australia","institution_ids":["https://openalex.org/I11701301"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048189316","display_name":"Yuqing Mu","orcid":"https://orcid.org/0000-0002-6569-781X","observed_orcids":["https://orcid.org/0000-0002-6569-781X"]},"institutions":[{"id":"https://openalex.org/I11701301","display_name":"Griffith University","ror":"https://ror.org/02sc3r913","country_code":"AU","type":"education","lineage":["https://openalex.org/I11701301"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Yuqing Mu","raw_affiliation_strings":["School of Medicine and Dentistry Griffith University  Southport Queensland Australia"],"raw_orcid":"https://orcid.org/0000-0002-6569-781X","affiliations":[{"raw_affiliation_string":"School of Medicine and Dentistry Griffith University  Southport Queensland Australia","institution_ids":["https://openalex.org/I11701301"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063353551","display_name":"Dinh Thien Xuan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1292875679","display_name":"Commonwealth Scientific and Industrial Research Organisation","ror":"https://ror.org/03qn8fb07","country_code":"AU","type":"government","lineage":["https://openalex.org/I1292875679","https://openalex.org/I2801453606","https://openalex.org/I4387156119"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Thien Xuan Dinh","raw_affiliation_strings":["The Commonwealth Scientific and Industrial Research Organisation  Clayton South Victoria Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Commonwealth Scientific and Industrial Research Organisation  Clayton South Victoria Australia","institution_ids":["https://openalex.org/I1292875679"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051762810","display_name":"Yin Xiao","orcid":"https://orcid.org/0000-0003-1785-3491","observed_orcids":["https://orcid.org/0000-0003-1785-3491"]},"institutions":[{"id":"https://openalex.org/I11701301","display_name":"Griffith University","ror":"https://ror.org/02sc3r913","country_code":"AU","type":"education","lineage":["https://openalex.org/I11701301"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Yin Xiao","raw_affiliation_strings":["School of Medicine and Dentistry Griffith University  Southport Queensland Australia"],"raw_orcid":"https://orcid.org/0000-0003-1785-3491","affiliations":[{"raw_affiliation_string":"School of Medicine and Dentistry Griffith University  Southport Queensland Australia","institution_ids":["https://openalex.org/I11701301"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064713378","display_name":"Dzung Viet Dao","orcid":"https://orcid.org/0000-0002-6348-0879","observed_orcids":["https://orcid.org/0000-0002-6348-0879"]},"institutions":[{"id":"https://openalex.org/I11701301","display_name":"Griffith University","ror":"https://ror.org/02sc3r913","country_code":"AU","type":"education","lineage":["https://openalex.org/I11701301"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Dzung Viet Dao","raw_affiliation_strings":["School of Engineering and Built Environment Griffith University  Southport Queensland Australia"],"raw_orcid":"https://orcid.org/0000-0002-6348-0879","affiliations":[{"raw_affiliation_string":"School of Engineering and Built Environment Griffith University  Southport Queensland Australia","institution_ids":["https://openalex.org/I11701301"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022476782","display_name":"Yuen Kuan Yong","orcid":"https://orcid.org/0000-0001-7363-5304","observed_orcids":["https://orcid.org/0000-0001-7363-5304"]},"institutions":[{"id":"https://openalex.org/I78757542","display_name":"University of Newcastle Australia","ror":"https://ror.org/00eae9z71","country_code":"AU","type":"education","lineage":["https://openalex.org/I78757542"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Yuen Kuan Yong","raw_affiliation_strings":["School of Engineering The University of Newcastle  Callaghan New South Wales Australia"],"raw_orcid":"https://orcid.org/0000-0001-7363-5304","affiliations":[{"raw_affiliation_string":"School of Engineering The University of Newcastle  Callaghan New South Wales Australia","institution_ids":["https://openalex.org/I78757542"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5066458315","display_name":"Van Thanh Dau","orcid":"https://orcid.org/0000-0002-8242-9884","observed_orcids":["https://orcid.org/0000-0002-8242-9884"]},"institutions":[{"id":"https://openalex.org/I11701301","display_name":"Griffith University","ror":"https://ror.org/02sc3r913","country_code":"AU","type":"education","lineage":["https://openalex.org/I11701301"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Van Thanh Dau","raw_affiliation_strings":["School of Engineering and Built Environment Griffith University  Southport Queensland Australia"],"raw_orcid":"https://orcid.org/0000-0002-8242-9884","affiliations":[{"raw_affiliation_string":"School of Engineering and Built Environment Griffith University  Southport Queensland Australia","institution_ids":["https://openalex.org/I11701301"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5022476782","https://openalex.org/A5066458315","https://openalex.org/A5071015557"],"corresponding_institution_ids":["https://openalex.org/I11701301","https://openalex.org/I78757542"],"apc_list":{"value":4680,"currency":"USD","value_usd":4680},"apc_paid":{"value":4680,"currency":"USD","value_usd":4680},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10704","display_name":"Advancements in Transdermal Drug Delivery","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10704","display_name":"Advancements in Transdermal Drug Delivery","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10729","display_name":"Electrospun Nanofibers in Biomedical Applications","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12776","display_name":"Electrohydrodynamics and Fluid Dynamics","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microneedles","display_name":"microneedles","score":0.9750000238418579},{"id":"https://openalex.org/keywords/transdermal-drug-delivery","display_name":"transdermal drug delivery","score":0.8949999809265137},{"id":"https://openalex.org/keywords/drug-coating","display_name":"drug coating","score":0.6660000085830688},{"id":"https://openalex.org/keywords/mesoporous-silica-nanoparticles","display_name":"mesoporous silica nanoparticles","score":0.8529999852180481},{"id":"https://openalex.org/keywords/antibacterial-activity","display_name":"antibacterial activity","score":0.9369999766349792},{"id":"https://openalex.org/keywords/charge-accumulation","display_name":"charge accumulation","score":0.8510000109672546},{"id":"https://openalex.org/keywords/voltage-pulses","display_name":"pulse voltage","score":0.5090000033378601}],"concepts":[{"id":"https://openalex.org/C205679159","wikidata":"https://www.wikidata.org/wiki/Q3375179","display_name":"Transdermal","level":2,"score":0.8623999953269958},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.760699987411499},{"id":"https://openalex.org/C136525101","wikidata":"https://www.wikidata.org/wiki/Q5428139","display_name":"Fabrication","level":3,"score":0.7271000146865845},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.6729999780654907},{"id":"https://openalex.org/C2781448156","wikidata":"https://www.wikidata.org/wiki/Q1570182","display_name":"Coating","level":2,"score":0.6202999949455261},{"id":"https://openalex.org/C2777230088","wikidata":"https://www.wikidata.org/wiki/Q864426","display_name":"Biocompatibility","level":2,"score":0.49480000138282776},{"id":"https://openalex.org/C2779820397","wikidata":"https://www.wikidata.org/wiki/Q1392806","display_name":"Drug delivery","level":2,"score":0.48559999465942383},{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.4650999903678894},{"id":"https://openalex.org/C194451485","wikidata":"https://www.wikidata.org/wiki/Q1327575","display_name":"Electrospray","level":3,"score":0.4431999921798706},{"id":"https://openalex.org/C82776694","wikidata":"https://www.wikidata.org/wiki/Q380049","display_name":"Mesoporous material","level":3,"score":0.42649999260902405},{"id":"https://openalex.org/C64297162","wikidata":"https://www.wikidata.org/wiki/Q1987070","display_name":"Deposition (geology)","level":3,"score":0.4036000072956085},{"id":"https://openalex.org/C133386390","wikidata":"https://www.wikidata.org/wiki/Q184996","display_name":"Dielectric","level":2,"score":0.38119998574256897},{"id":"https://openalex.org/C2777496208","wikidata":"https://www.wikidata.org/wiki/Q17156473","display_name":"Mesoporous silica","level":4,"score":0.3569999933242798},{"id":"https://openalex.org/C2775842315","wikidata":"https://www.wikidata.org/wiki/Q1145270","display_name":"Transdermal patch","level":3,"score":0.33980000019073486},{"id":"https://openalex.org/C49241924","wikidata":"https://www.wikidata.org/wiki/Q2270123","display_name":"Dip-coating","level":3,"score":0.2685000002384186},{"id":"https://openalex.org/C2777822432","wikidata":"https://www.wikidata.org/wiki/Q216681","display_name":"In situ","level":2,"score":0.26260000467300415}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1002/admt.71464","doi":"https://doi.org/10.1002/admt.71464","is_oa":true,"landing_page_url":"https://doi.org/10.1002/admt.71464","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/admt.71464","source":{"id":"https://openalex.org/S2765038284","display_name":"Advanced Materials Technologies","issn_l":"2365-709X","issn":["2365-709X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advanced Materials Technologies","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1002/admt.71464","doi":"https://doi.org/10.1002/admt.71464","is_oa":true,"landing_page_url":"https://doi.org/10.1002/admt.71464","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/admt.71464","source":{"id":"https://openalex.org/S2765038284","display_name":"Advanced Materials Technologies","issn_l":"2365-709X","issn":["2365-709X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advanced Materials Technologies","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.6000000238418579,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320334704","display_name":"Australian Research Council","ror":"https://ror.org/05mmh0f86"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7225625604.pdf","grobid_xml":"https://content.openalex.org/works/W7225625604.grobid-xml"},"referenced_works_count":57,"referenced_works":["https://openalex.org/W1936827687","https://openalex.org/W2014975258","https://openalex.org/W2021898692","https://openalex.org/W2075350111","https://openalex.org/W2089143024","https://openalex.org/W2105493802","https://openalex.org/W2154256980","https://openalex.org/W2791840228","https://openalex.org/W2969608053","https://openalex.org/W3114657416","https://openalex.org/W3150453497","https://openalex.org/W4281476123","https://openalex.org/W4313891011","https://openalex.org/W4318426636","https://openalex.org/W4366261646","https://openalex.org/W4380184651","https://openalex.org/W4380714805","https://openalex.org/W4382058854","https://openalex.org/W4385810963","https://openalex.org/W4386157742","https://openalex.org/W4386546725","https://openalex.org/W4387332506","https://openalex.org/W4387699912","https://openalex.org/W4390693934","https://openalex.org/W4390821363","https://openalex.org/W4390959388","https://openalex.org/W4392191326","https://openalex.org/W4399246506","https://openalex.org/W4400904871","https://openalex.org/W4401147933","https://openalex.org/W4402317746","https://openalex.org/W4407348549","https://openalex.org/W4407884037","https://openalex.org/W4408549457","https://openalex.org/W4409360548","https://openalex.org/W4409983271","https://openalex.org/W4410190891","https://openalex.org/W4410529291","https://openalex.org/W4411971313","https://openalex.org/W4412892731","https://openalex.org/W4413320016","https://openalex.org/W4413526920","https://openalex.org/W4414287673","https://openalex.org/W4414418541","https://openalex.org/W4414522769","https://openalex.org/W4415984583","https://openalex.org/W4416329595","https://openalex.org/W4416431395","https://openalex.org/W4416438746","https://openalex.org/W4416671067","https://openalex.org/W7082002974","https://openalex.org/W7117895169","https://openalex.org/W7119501531","https://openalex.org/W7130426717","https://openalex.org/W7131315326","https://openalex.org/W7134206395","https://openalex.org/W7161632441"],"related_works":["https://openalex.org/W4415362039","https://openalex.org/W4413320016","https://openalex.org/W4410190891","https://openalex.org/W4409241244","https://openalex.org/W2046078151","https://openalex.org/W2588919946","https://openalex.org/W2915004791","https://openalex.org/W4412684944","https://openalex.org/W2600478716","https://openalex.org/W2894744226"],"abstract_inverted_index":{"ABSTRACT":[0],"Universal":[1],"transdermal":[2,189],"drug":[3,154,190],"delivery":[4,191],"remains":[5],"constrained":[6],"by":[7,144],"the":[8,22,32,60,67,113,119,124,128,138,171,183],"material":[9],"dependencies":[10],"and":[11,31,43,66,83,95,102,122,146,160,179],"fabrication":[12,62],"complexities":[13],"of":[14,41,63,70,115,127,141,173,185],"current":[15],"microneedle":[16],"(MN)":[17],"technologies.":[18],"Here,":[19],"we":[20],"present":[21],"innovative":[23],"substrate\u2010independent":[24],"pulsating":[25],"in":[26,33,106,131,164,165],"situ":[27,34],"dried":[28],"electrostretching":[29],"(SI\u2010PIDES)":[30],"focused":[35],"electrospray":[36],"deposition":[37,107,133],"(IFED)":[38],"platform":[39,143],"capable":[40],"fabricating":[42],"precisely":[44],"coating":[45,69,147],"MNs":[46,65],"on":[47,118],"flexible,":[48],"non\u2010conductive":[49,120],"dielectric":[50,74],"patches.":[51,76],"By":[52],"leveraging":[53],"polarized":[54,129],"pulsed":[55],"voltage,":[56],"these":[57],"methods":[58],"enable":[59],"mold\u2010free":[61],"polymeric":[64],"precise":[68],"drug\u2010loaded":[71],"substances":[72],"onto":[73],"MN":[75,87,121],"This":[77],"novel":[78],"discovery":[79],"provides":[80],"an":[81],"integrated":[82],"simplified":[84],"workflow":[85],"for":[86,182],"patch":[88],"fabrication.":[89],"Experimental":[90],"results":[91],"demonstrate":[92,137],"that":[93],"SI\u2010PIDES":[94],"IFED":[96],"produce":[97],"mechanically":[98],"robust":[99],"core\u2013sheath":[100],"microneedles":[101],"gain":[103],"considerable":[104],"improvements":[105],"accuracy.":[108],"Multiphysics":[109],"particle":[110],"simulations":[111],"revealed":[112],"effects":[114],"charge":[116],"accumulation":[117],"confirmed":[123],"crucial":[125],"role":[126],"voltage":[130],"maintaining":[132],"efficiency.":[134],"We":[135],"further":[136],"practical":[139],"utility":[140],"this":[142],"synthesizing":[145],"zinc/magnesium\u2010doped":[148],"mesoporous":[149],"silica":[150],"nanoparticles":[151],"as":[152,176],"a":[153,177],"model,":[155],"which":[156],"showed":[157],"excellent":[158],"biocompatibility":[159],"potent":[161],"antibacterial":[162],"suppression":[163],"vitro":[166],"assays.":[167],"These":[168],"findings":[169],"emphasize":[170],"potential":[172],"our":[174],"technology":[175],"simple":[178],"physics\u2010driven":[180],"approach":[181],"development":[184],"scalable,":[186],"next\u2010generation":[187],"high\u2010precision":[188],"systems.":[192]},"counts_by_year":[],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2026-11-10T00:00:00"}