{"id":"https://openalex.org/W7225618877","doi":"https://doi.org/10.1088/1361-6528/aebfa8","title":"Morphology-dependent Fe3O4 nanozymes with NIR-enhanced peroxidase-like activity for antibacterial wound therapy","display_name":"Morphology-dependent Fe3O4 nanozymes with NIR-enhanced peroxidase-like activity for antibacterial wound therapy","publication_year":2026,"publication_date":"2026-11-09","ids":{"openalex":"https://openalex.org/W7225618877","doi":"https://doi.org/10.1088/1361-6528/aebfa8","pmid":"https://pubmed.ncbi.nlm.nih.gov/43002787"},"language":"en","primary_location":{"id":"doi:10.1088/1361-6528/aebfa8","doi":"https://doi.org/10.1088/1361-6528/aebfa8","is_oa":true,"landing_page_url":"https://doi.org/10.1088/1361-6528/aebfa8","pdf_url":"https://iopscience.iop.org/article/10.1088/1361-6528/aebfa8/pdf","source":{"id":"https://openalex.org/S206811868","display_name":"Nanotechnology","issn_l":"0957-4484","issn":["0957-4484","1361-6528"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320083","host_organization_name":"IOP Publishing","host_organization_lineage":["https://openalex.org/P4310320083","https://openalex.org/P4310311669"],"host_organization_lineage_names":["IOP Publishing","Institute of Physics"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nanotechnology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://iopscience.iop.org/article/10.1088/1361-6528/aebfa8/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5161361846","display_name":"Li Deng","orcid":"https://orcid.org/0009-0004-3837-593X","observed_orcids":["https://orcid.org/0009-0004-3837-593X"]},"institutions":[{"id":"https://openalex.org/I149594827","display_name":"Xidian University","ror":"https://ror.org/05s92vm98","country_code":"CN","type":"education","lineage":["https://openalex.org/I149594827"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Li Deng","raw_affiliation_strings":["Xidian University"],"raw_orcid":"https://orcid.org/0009-0004-3837-593X","affiliations":[{"raw_affiliation_string":"Xidian University","institution_ids":["https://openalex.org/I149594827"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113403306","display_name":"Yanrui JING","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I149594827","display_name":"Xidian University","ror":"https://ror.org/05s92vm98","country_code":"CN","type":"education","lineage":["https://openalex.org/I149594827"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yanrui Jing","raw_affiliation_strings":["Xidian University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Xidian University","institution_ids":["https://openalex.org/I149594827"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161360067","display_name":"Langjia Awang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I149594827","display_name":"Xidian University","ror":"https://ror.org/05s92vm98","country_code":"CN","type":"education","lineage":["https://openalex.org/I149594827"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Langjia Awang","raw_affiliation_strings":["Xidian University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Xidian University","institution_ids":["https://openalex.org/I149594827"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161344942","display_name":"Danyang Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I149594827","display_name":"Xidian University","ror":"https://ror.org/05s92vm98","country_code":"CN","type":"education","lineage":["https://openalex.org/I149594827"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Danyang Wang","raw_affiliation_strings":["Xidian University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Xidian University","institution_ids":["https://openalex.org/I149594827"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102829836","display_name":"Yichen Shen","orcid":"https://orcid.org/0000-0003-3800-2143","observed_orcids":["https://orcid.org/0000-0003-3800-2143","https://orcid.org/0000-0002-7512-3756","https://orcid.org/0000-0002-0278-0771"]},"institutions":[{"id":"https://openalex.org/I149594827","display_name":"Xidian University","ror":"https://ror.org/05s92vm98","country_code":"CN","type":"education","lineage":["https://openalex.org/I149594827"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yichen Shen","raw_affiliation_strings":["Xidian University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Xidian University","institution_ids":["https://openalex.org/I149594827"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161347034","display_name":"Jinze Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I149594827","display_name":"Xidian University","ror":"https://ror.org/05s92vm98","country_code":"CN","type":"education","lineage":["https://openalex.org/I149594827"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jinze Li","raw_affiliation_strings":["Xidian University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Xidian University","institution_ids":["https://openalex.org/I149594827"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5158447860","display_name":"Zhuang Chen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I149594827","display_name":"Xidian University","ror":"https://ror.org/05s92vm98","country_code":"CN","type":"education","lineage":["https://openalex.org/I149594827"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhuang Chen","raw_affiliation_strings":["Xidian University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Xidian University","institution_ids":["https://openalex.org/I149594827"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022883932","display_name":"Hao Sun","orcid":"https://orcid.org/0000-0003-0189-1784","observed_orcids":["https://orcid.org/0000-0003-0189-1784"]},"institutions":[{"id":"https://openalex.org/I149594827","display_name":"Xidian University","ror":"https://ror.org/05s92vm98","country_code":"CN","type":"education","lineage":["https://openalex.org/I149594827"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hao Sun","raw_affiliation_strings":["Xidian University"],"raw_orcid":"https://orcid.org/0000-0003-0189-1784","affiliations":[{"raw_affiliation_string":"Xidian University","institution_ids":["https://openalex.org/I149594827"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073580794","display_name":"Peng Yang","orcid":"https://orcid.org/0000-0003-1535-2538","observed_orcids":["https://orcid.org/0000-0003-1535-2538","https://orcid.org/0009-0004-6914-8027"]},"institutions":[{"id":"https://openalex.org/I149594827","display_name":"Xidian University","ror":"https://ror.org/05s92vm98","country_code":"CN","type":"education","lineage":["https://openalex.org/I149594827"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Peng Yang","raw_affiliation_strings":["Xidian University"],"raw_orcid":"https://orcid.org/0000-0003-1535-2538","affiliations":[{"raw_affiliation_string":"Xidian University","institution_ids":["https://openalex.org/I149594827"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100664122","display_name":"Zhongliang Wang","orcid":"https://orcid.org/0000-0001-9388-149X","observed_orcids":["https://orcid.org/0000-0001-9388-149X"]},"institutions":[{"id":"https://openalex.org/I149594827","display_name":"Xidian University","ror":"https://ror.org/05s92vm98","country_code":"CN","type":"education","lineage":["https://openalex.org/I149594827"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Zhongliang Wang","raw_affiliation_strings":["Xidian University"],"raw_orcid":"https://orcid.org/0000-0001-9388-149X","affiliations":[{"raw_affiliation_string":"Xidian University","institution_ids":["https://openalex.org/I149594827"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5100664122","https://openalex.org/A5161344942"],"corresponding_institution_ids":["https://openalex.org/I149594827"],"apc_list":{"value":3325,"currency":"USD","value_usd":3325},"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12302","display_name":"Advanced Nanomaterials in Catalysis","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12302","display_name":"Advanced Nanomaterials in Catalysis","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10782","display_name":"Nanoplatforms for cancer theranostics","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10771","display_name":"Wound Healing and Treatments","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/peroxidase-like-activity","display_name":"peroxidase-like activity","score":0.9919999837875366},{"id":"https://openalex.org/keywords/near-infrared-irradiation","display_name":"near-infrared irradiation","score":0.9599999785423279},{"id":"https://openalex.org/keywords/escherichia-coli","display_name":"Escherichia coli","score":0.8880000114440918},{"id":"https://openalex.org/keywords/hydroxyl-radical-production","display_name":"hydroxyl radical generation","score":0.8330000042915344},{"id":"https://openalex.org/keywords/octahedral-nanoparticles","display_name":"octahedral nanoparticles","score":0.6779999732971191},{"id":"https://openalex.org/keywords/infected-wound-healing","display_name":"infected wound healing","score":0.7829999923706055},{"id":"https://openalex.org/keywords/morphology-engineering","display_name":"morphology engineering","score":0.47999998927116394}],"concepts":[{"id":"https://openalex.org/C182606246","wikidata":"https://www.wikidata.org/wiki/Q7187926","display_name":"Photothermal therapy","level":2,"score":0.7451000213623047},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.5957000255584717},{"id":"https://openalex.org/C2780104969","wikidata":"https://www.wikidata.org/wiki/Q4774530","display_name":"Antibacterial activity","level":3,"score":0.5837000012397766},{"id":"https://openalex.org/C4937899","wikidata":"https://www.wikidata.org/wiki/Q68541106","display_name":"Antimicrobial","level":2,"score":0.5688999891281128},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.5440999865531921},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.4334999918937683},{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.42320001125335693},{"id":"https://openalex.org/C13965031","wikidata":"https://www.wikidata.org/wiki/Q243545","display_name":"Nuclear chemistry","level":1,"score":0.41940000653266907},{"id":"https://openalex.org/C2780269544","wikidata":"https://www.wikidata.org/wiki/Q1509074","display_name":"Wound healing","level":2,"score":0.4115999937057495},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.2962999939918518},{"id":"https://openalex.org/C2993040405","wikidata":"https://www.wikidata.org/wiki/Q900221","display_name":"Fenton reaction","level":3,"score":0.2791000008583069},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.26930001378059387},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.2563999891281128},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.25200000405311584}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1088/1361-6528/aebfa8","doi":"https://doi.org/10.1088/1361-6528/aebfa8","is_oa":true,"landing_page_url":"https://doi.org/10.1088/1361-6528/aebfa8","pdf_url":"https://iopscience.iop.org/article/10.1088/1361-6528/aebfa8/pdf","source":{"id":"https://openalex.org/S206811868","display_name":"Nanotechnology","issn_l":"0957-4484","issn":["0957-4484","1361-6528"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320083","host_organization_name":"IOP Publishing","host_organization_lineage":["https://openalex.org/P4310320083","https://openalex.org/P4310311669"],"host_organization_lineage_names":["IOP Publishing","Institute of Physics"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nanotechnology","raw_type":"journal-article"},{"id":"pmid:43002787","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/43002787","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nanotechnology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1088/1361-6528/aebfa8","doi":"https://doi.org/10.1088/1361-6528/aebfa8","is_oa":true,"landing_page_url":"https://doi.org/10.1088/1361-6528/aebfa8","pdf_url":"https://iopscience.iop.org/article/10.1088/1361-6528/aebfa8/pdf","source":{"id":"https://openalex.org/S206811868","display_name":"Nanotechnology","issn_l":"0957-4484","issn":["0957-4484","1361-6528"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320083","host_organization_name":"IOP Publishing","host_organization_lineage":["https://openalex.org/P4310320083","https://openalex.org/P4310311669"],"host_organization_lineage_names":["IOP Publishing","Institute of Physics"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nanotechnology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.46810001134872437,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320323230","display_name":"Xidian University","ror":"https://ror.org/05s92vm98"},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null},{"id":"https://openalex.org/F4320336350","display_name":"Key Research and Development Projects of Shaanxi Province","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7225618877.pdf","grobid_xml":"https://content.openalex.org/works/W7225618877.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4283324844","https://openalex.org/W4300862001","https://openalex.org/W4406617316","https://openalex.org/W7136204173","https://openalex.org/W4413040723","https://openalex.org/W4382930242","https://openalex.org/W4388458775","https://openalex.org/W4414783442","https://openalex.org/W7225449624","https://openalex.org/W4389732997"],"abstract_inverted_index":{"Bacterial":[0],"infection":[1],"severely":[2],"impairs":[3],"wound":[4,150,157,161,185],"repair,":[5],"and":[6,21,26,34,41,71,85,110,131,138,183],"antibiotic-based":[7],"treatment":[8],"is":[9],"increasingly":[10],"challenged":[11],"by":[12],"antimicrobial":[13],"resistance.":[14],"Herein,":[15],"Fe3O4":[16,53,80,176],"nanozymes":[17,46,81],"with":[18,83,122,153],"octahedral,":[19],"spherical,":[20],"cubic":[22],"morphologies":[23],"were":[24],"synthesized":[25],"systematically":[27],"compared":[28],"for":[29,115,179],"peroxidase-like":[30],"activity,":[31,60],"photothermal":[32,108],"performance,":[33],"antibacterial":[35,181],"efficacy.":[36],"Despite":[37],"their":[38],"comparable":[39],"sizes":[40],"good":[42],"dispersibility,":[43],"the":[44,57,93,105,160],"three":[45],"exhibited":[47],"distinct":[48],"morphology-dependent":[49],"catalytic":[50,77],"activities.":[51],"Octahedral":[52],"nanoparticles":[54],"(O-IONP)":[55],"showed":[56],"highest":[58,72],"POD-like":[59,116],"strongest":[61],"hydroxyl":[62],"radical":[63],"generation,":[64],"lowest":[65],"apparent":[66],"Michaelis":[67],"constant":[68],"toward":[69,144],"TMB,":[70],"maximum":[73],"reaction":[74],"velocity.":[75],"The":[76],"activity":[78],"of":[79,95],"increased":[82],"temperature":[84,113],"reached":[86,111],"an":[87,147],"optimum":[88],"near":[89],"55":[90],"oC,":[91],"indicating":[92],"feasibility":[94],"photothermalenhanced":[96],"catalysis.":[97,117],"Under":[98],"808":[99],"nm":[100],"near-infrared":[101],"irradiation,":[102],"O-IONP":[103,120,152],"displayed":[104],"most":[106],"efficient":[107],"response":[109],"a":[112,173],"favourable":[114],"In":[118,146],"vitro,":[119],"combined":[121],"NIR":[123,154],"reduced":[124],"Escherichia":[125],"coli":[126],"viability":[127],"to":[128,164],"approximately":[129,165],"2%":[130],"caused":[132],"severe":[133],"bacterial":[134],"membrane":[135],"deformation,":[136],"collapse,":[137],"rupture,":[139],"while":[140],"maintaining":[141],"acceptable":[142],"cytocompatibility":[143],"macrophages.":[145],"E.":[148],"coli-infected":[149],"model,":[151],"significantly":[155],"accelerated":[156],"closure,":[158],"reducing":[159],"remaining":[162],"ratio":[163],"13%":[166],"on":[167],"day":[168],"10.":[169],"This":[170],"work":[171],"demonstrates":[172],"simple":[174],"morphology-engineered":[175],"nanozyme":[177],"platform":[178],"photothermal-catalytic":[180],"therapy":[182],"infected":[184],"healing.":[186]},"counts_by_year":[],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2026-11-10T00:00:00"}