{"id":"https://openalex.org/W7225597909","doi":"https://doi.org/10.17816/brmma707530","title":"Changes in and prognostic value of platelet parameters in wounded with polytrauma","display_name":"Changes in and prognostic value of platelet parameters in wounded with polytrauma","publication_year":2026,"publication_date":"2026-11-08","ids":{"openalex":"https://openalex.org/W7225597909","doi":"https://doi.org/10.17816/brmma707530"},"language":"en","primary_location":{"id":"doi:10.17816/brmma707530","doi":"https://doi.org/10.17816/brmma707530","is_oa":true,"landing_page_url":"https://doi.org/10.17816/brmma707530","pdf_url":"https://xn--2023-43damrhab1ba4ccoagg5bs7j0i.xn--p1ai/wp-content/uploads/2023/03/nkr_politravma.pdf","source":{"id":"https://openalex.org/S4210173503","display_name":"Bulletin of the Russian Military Medical Academy","issn_l":"1682-7392","issn":["1682-7392","2687-1424"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["russia-white-list-1"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bulletin of the Russian Military Medical Academy","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://xn--2023-43damrhab1ba4ccoagg5bs7j0i.xn--p1ai/wp-content/uploads/2023/03/nkr_politravma.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5041016788","display_name":"Evgeniy  V. Kryukov","orcid":"https://orcid.org/0000-0002-8396-1936","observed_orcids":["https://orcid.org/0000-0002-8396-1936"]},"institutions":[{"id":"https://openalex.org/I2801546011","display_name":"S. M. Kirov Military Medical Academy","ror":"https://ror.org/035k4m812","country_code":"RU","type":"education","lineage":["https://openalex.org/I2801546011","https://openalex.org/I4210150315"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Evgeniy V. Kryukov","raw_affiliation_strings":["Kirov Military Medical Academy"],"raw_orcid":"https://orcid.org/0000-0002-8396-1936","affiliations":[{"raw_affiliation_string":"Kirov Military Medical Academy","institution_ids":["https://openalex.org/I2801546011"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090762290","display_name":"Vladimir B. Grinevich","orcid":"https://orcid.org/0000-0002-1095-8787","observed_orcids":["https://orcid.org/0000-0002-1095-8787"]},"institutions":[{"id":"https://openalex.org/I2801546011","display_name":"S. M. Kirov Military Medical Academy","ror":"https://ror.org/035k4m812","country_code":"RU","type":"education","lineage":["https://openalex.org/I2801546011","https://openalex.org/I4210150315"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Vladimir B. Grinevich","raw_affiliation_strings":["Kirov Military Medical Academy"],"raw_orcid":"https://orcid.org/0000-0002-1095-8787","affiliations":[{"raw_affiliation_string":"Kirov Military Medical Academy","institution_ids":["https://openalex.org/I2801546011"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001286621","display_name":"S. P. Salikova","orcid":"https://orcid.org/0000-0003-4839-9578","observed_orcids":["https://orcid.org/0000-0003-4839-9578"]},"institutions":[{"id":"https://openalex.org/I2801546011","display_name":"S. M. Kirov Military Medical Academy","ror":"https://ror.org/035k4m812","country_code":"RU","type":"education","lineage":["https://openalex.org/I2801546011","https://openalex.org/I4210150315"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Svetlana P. Salikova","raw_affiliation_strings":["Kirov Military Medical Academy"],"raw_orcid":"https://orcid.org/0000-0003-4839-9578","affiliations":[{"raw_affiliation_string":"Kirov Military Medical Academy","institution_ids":["https://openalex.org/I2801546011"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5000351156","display_name":"Arseny N. Sorokin","orcid":"https://orcid.org/0000-0001-7921-667X","observed_orcids":["https://orcid.org/0000-0001-7921-667X"]},"institutions":[{"id":"https://openalex.org/I2801546011","display_name":"S. M. Kirov Military Medical Academy","ror":"https://ror.org/035k4m812","country_code":"RU","type":"education","lineage":["https://openalex.org/I2801546011","https://openalex.org/I4210150315"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Arseny N. Sorokin","raw_affiliation_strings":["Kirov Military Medical Academy"],"raw_orcid":"https://orcid.org/0000-0001-7921-667X","affiliations":[{"raw_affiliation_string":"Kirov Military Medical Academy","institution_ids":["https://openalex.org/I2801546011"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I2801546011"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"28","issue":"4","first_page":"499","last_page":"508"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11116","display_name":"Trauma, Hemostasis, Coagulopathy, Resuscitation","score":0.8490999937057495,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11116","display_name":"Trauma, Hemostasis, Coagulopathy, Resuscitation","score":0.8490999937057495,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10746","display_name":"Platelet Disorders and Treatments","score":0.09510000050067902,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10693","display_name":"Blood transfusion and management","score":0.03720000013709068,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/polytrauma","display_name":"polytrauma","score":0.9929999709129333},{"id":"https://openalex.org/keywords/platelet-indices","display_name":"platelet indices","score":0.8519999980926514},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.8610000014305115},{"id":"https://openalex.org/keywords/fatal-outcome","display_name":"fatal outcome","score":0.6050000190734863},{"id":"https://openalex.org/keywords/megakaryopoiesis","display_name":"megakaryopoiesis","score":0.8880000114440918},{"id":"https://openalex.org/keywords/thrombocytopenia","display_name":"thrombocytopenia","score":0.9010000228881836},{"id":"https://openalex.org/keywords/plateletcrit","display_name":"plateletcrit","score":0.8840000033378601},{"id":"https://openalex.org/keywords/mean-platelet-volume","display_name":"mean platelet volume","score":0.9950000047683716},{"id":"https://openalex.org/keywords/platelet-distribution-width","display_name":"platelet distribution width","score":0.9959999918937683},{"id":"https://openalex.org/keywords/large-platelets","display_name":"large platelets","score":0.902999997138977},{"id":"https://openalex.org/keywords/hemorrhagic-syndrome","display_name":"hemorrhagic syndrome","score":0.7599999904632568},{"id":"https://openalex.org/keywords/venous-thromboembolism","display_name":"venous thromboembolism","score":0.8980000019073486},{"id":"https://openalex.org/keywords/gunshot-wounds","display_name":"gunshot wounds","score":0.722000002861023},{"id":"https://openalex.org/keywords/injury-severity","display_name":"injury severity","score":0.5009999871253967},{"id":"https://openalex.org/keywords/caprini-score","display_name":"Caprini score","score":0.968999981880188}],"concepts":[{"id":"https://openalex.org/C2776692886","wikidata":"https://www.wikidata.org/wiki/Q2103168","display_name":"Polytrauma","level":2,"score":0.8526999950408936},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8169000148773193},{"id":"https://openalex.org/C89560881","wikidata":"https://www.wikidata.org/wiki/Q101026","display_name":"Platelet","level":2,"score":0.7838000059127808},{"id":"https://openalex.org/C2776958478","wikidata":"https://www.wikidata.org/wiki/Q14914622","display_name":"Thrombopoiesis","level":5,"score":0.704200029373169},{"id":"https://openalex.org/C190481736","wikidata":"https://www.wikidata.org/wiki/Q6803639","display_name":"Mean platelet volume","level":3,"score":0.5418000221252441},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5139999985694885},{"id":"https://openalex.org/C194409129","wikidata":"https://www.wikidata.org/wiki/Q103824","display_name":"Hematology","level":2,"score":0.4959000051021576},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.4171999990940094},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.37529999017715454},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.32670000195503235},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.32330000400543213},{"id":"https://openalex.org/C37557685","wikidata":"https://www.wikidata.org/wiki/Q1896673","display_name":"Blood volume","level":2,"score":0.3021000027656555},{"id":"https://openalex.org/C43044207","wikidata":"https://www.wikidata.org/wiki/Q618363","display_name":"Venous blood","level":2,"score":0.29750001430511475},{"id":"https://openalex.org/C85004164","wikidata":"https://www.wikidata.org/wiki/Q1089964","display_name":"Injury Severity Score","level":4,"score":0.29100000858306885},{"id":"https://openalex.org/C2993758460","wikidata":"https://www.wikidata.org/wiki/Q65067531","display_name":"Hematology analyzer","level":2,"score":0.2906999886035919},{"id":"https://openalex.org/C46699223","wikidata":"https://www.wikidata.org/wiki/Q11078","display_name":"Endocrine system","level":3,"score":0.28839999437332153},{"id":"https://openalex.org/C109159458","wikidata":"https://www.wikidata.org/wiki/Q919283","display_name":"Haematopoiesis","level":3,"score":0.28450000286102295},{"id":"https://openalex.org/C110121322","wikidata":"https://www.wikidata.org/wiki/Q865811","display_name":"Distribution (mathematics)","level":2,"score":0.2689000070095062},{"id":"https://openalex.org/C2908742493","wikidata":"https://www.wikidata.org/wiki/Q101026","display_name":"Blood Platelet Disorders","level":4,"score":0.2669000029563904},{"id":"https://openalex.org/C2780076729","wikidata":"https://www.wikidata.org/wiki/Q1752571","display_name":"Myelofibrosis","level":3,"score":0.2587999999523163},{"id":"https://openalex.org/C3018697912","wikidata":"https://www.wikidata.org/wiki/Q179217","display_name":"Platelet activation","level":3,"score":0.25760000944137573},{"id":"https://openalex.org/C2777914111","wikidata":"https://www.wikidata.org/wiki/Q1064904","display_name":"Major trauma","level":2,"score":0.2558000087738037}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.17816/brmma707530","doi":"https://doi.org/10.17816/brmma707530","is_oa":true,"landing_page_url":"https://doi.org/10.17816/brmma707530","pdf_url":"https://xn--2023-43damrhab1ba4ccoagg5bs7j0i.xn--p1ai/wp-content/uploads/2023/03/nkr_politravma.pdf","source":{"id":"https://openalex.org/S4210173503","display_name":"Bulletin of the Russian Military Medical Academy","issn_l":"1682-7392","issn":["1682-7392","2687-1424"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["russia-white-list-1"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bulletin of the Russian Military Medical Academy","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.17816/brmma707530","doi":"https://doi.org/10.17816/brmma707530","is_oa":true,"landing_page_url":"https://doi.org/10.17816/brmma707530","pdf_url":"https://xn--2023-43damrhab1ba4ccoagg5bs7j0i.xn--p1ai/wp-content/uploads/2023/03/nkr_politravma.pdf","source":{"id":"https://openalex.org/S4210173503","display_name":"Bulletin of the Russian Military Medical Academy","issn_l":"1682-7392","issn":["1682-7392","2687-1424"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["russia-white-list-1"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bulletin of the Russian Military Medical Academy","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7225597909.pdf","grobid_xml":"https://content.openalex.org/works/W7225597909.grobid-xml"},"referenced_works_count":16,"referenced_works":["https://openalex.org/W1549169589","https://openalex.org/W2040965140","https://openalex.org/W2761617805","https://openalex.org/W3016854158","https://openalex.org/W3138626431","https://openalex.org/W3216817587","https://openalex.org/W4280583789","https://openalex.org/W4289518223","https://openalex.org/W4313303840","https://openalex.org/W4390976719","https://openalex.org/W4391174365","https://openalex.org/W4391759429","https://openalex.org/W4410461523","https://openalex.org/W4413818360","https://openalex.org/W6964094603","https://openalex.org/W7137931824"],"related_works":["https://openalex.org/W2366515263","https://openalex.org/W4389670169","https://openalex.org/W2260723225","https://openalex.org/W2320003659","https://openalex.org/W7137931824","https://openalex.org/W3183985155","https://openalex.org/W240229088","https://openalex.org/W4405339366","https://openalex.org/W7223260101","https://openalex.org/W2061363260"],"abstract_inverted_index":{"BACKGROUND:":[0],"Polytrauma":[1,158],"as":[2,76,78,135,137,290,292],"a":[3,178,184,208,246,263,271,341,375],"manifestation":[4],"of":[5,11,15,26,30,35,58,69,88,100,118,145,190,231,237,243,253,256,262,277,314,336,369,381,387],"combat":[6],"surgical":[7],"trauma":[8,140],"is":[9,47,329,364],"one":[10],"the":[12,20,24,27,33,53,67,98,106,123,138,154,187,201,204,213,218,229,234,241,249,254,274,312,355,367,370,378],"pressing":[13],"problems":[14],"modern":[16],"military":[17],"medicine.":[18],"Given":[19],"new":[21],"data":[22],"on":[23],"role":[25],"platelet":[28,70,92,94,169,215,219,257,297,304],"component":[29],"hematopoiesis":[31],"in":[32,38,43,61,72,168,211,266,273,295,325,344,360,377],"development":[34],"hemorrhagic":[36],"syndrome,":[37],"predicting":[39],"outcomes":[40],"and":[41,55,81,97,128,217,224,233,251,279,287,311,347,374],"complications":[42,150],"various":[44],"diseases,":[45],"there":[46],"an":[48,293,332],"urgent":[49],"need":[50],"to":[51,161,281,299,307,317,351],"analyze":[52],"quantitative":[54],"functional":[56,235,348,379],"parameters":[57,71,258],"circulating":[59,238,337,382],"platelets":[60,102,191,278,316,383],"traumatic":[62,388],"disease.":[63,389],"AIM:":[64],"To":[65],"assess":[66],"dynamics":[68,255],"wounded":[73,182,244,267],"with":[74,164,183,207,245,268,327,362,366],"polytrauma,":[75],"well":[77,136,291],"its":[79],"diagnostic":[80],"prognostic":[82,175],"significance.":[83],"METHODS:":[84],"The":[85,116,143],"total":[86,188,275],"number":[87,189,276,346],"platelets,":[89,338],"plateletcrit,":[90,212],"mean":[91,214,296],"volume,":[93],"distribution":[95,220,305],"width,":[96],"percentage":[99,313],"large":[101,315],"were":[103,259],"recorded":[104],"using":[105,122,153],"Medonic":[107],"630":[108],"Thor":[109],"hematology":[110],"analyzer":[111],"(Boule":[112],"Medical":[113],"AB,":[114],"Sweden).":[115],"severity":[117,141,250],"injuries":[119],"was":[120,151,159],"assessed":[121,152],"\u201cmilitary":[124,129],"field":[125,130],"surgery\u2014admission":[126],"status\u201d":[127],"surgery\u2014injury":[131],"(gunshot":[132],"wound)\u201d":[133],"scales,":[134],"Baker":[139],"score.":[142,156],"risk":[144],"developing":[146],"secondary":[147],"venous":[148],"thromboembolic":[149],"Caprini":[155],"RESULTS:":[157],"found":[160],"be":[162,173],"associated":[163,365],"consistent":[165],"dynamic":[166],"changes":[167],"parameters,":[170],"which":[171,227],"can":[172],"considered":[174],"factors":[176],"for":[177],"fatal":[179,247,264],"outcome.":[180],"In":[181,240],"favorable":[185,323],"prognosis,":[186],"increased":[192],"by":[193,197,331,340],"more":[194,300,308,318],"than":[195,283,301,309,319],"fourfold":[196],"day":[198,352],"20":[199,353],"after":[200,354],"injury.":[202,356],"At":[203],"same":[205],"time,":[206],"2-fold":[209],"increase":[210,294,343],"volume":[216,298],"width":[221,306],"decreased":[222],"1.3-fold":[223],"1.2-fold,":[225],"respectively,":[226,289],"reflects":[228],"reactivity":[230],"thrombopoiesis":[232],"activity":[236,349,380],"platelets.":[239],"group":[242],"outcome,":[248],"nature":[252],"reversed.":[260],"Predictors":[261],"outcome":[265],"polytrauma":[269,328,363],"included":[270],"decrease":[272,376],"plateletcrit":[280],"less":[282],"225.1":[284],"\u00d7":[285],"10\u00b3/\u03bcL":[286],"0.2%,":[288],"8.3":[302],"fL,":[303],"17.1%,":[310],"38.1%.":[320],"CONCLUSION:":[321],"A":[322],"prognosis":[324,359],"patients":[326,361],"determined":[330],"initially":[333,371],"normal":[334],"level":[335],"followed":[339],"significant":[342],"their":[345],"up":[350],"An":[357],"unfavorable":[358],"worsening":[368],"present":[372],"thrombocytopenia":[373],"throughout":[384],"all":[385],"stages":[386]},"counts_by_year":[],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2026-11-09T00:00:00"}