{"id":"https://openalex.org/W7225580713","doi":"https://doi.org/10.5281/zenodo.24055868","title":"FORMULATION AND EVALUATION OF HARD GELATIN CAPSULE OF POMALIDOMIDE","display_name":"FORMULATION AND EVALUATION OF HARD GELATIN CAPSULE OF POMALIDOMIDE","publication_year":2026,"publication_date":"2026-11-08","ids":{"openalex":"https://openalex.org/W7225580713","doi":"https://doi.org/10.5281/zenodo.24055868"},"language":"en","primary_location":{"id":"doi:10.5281/zenodo.24055868","doi":"https://doi.org/10.5281/zenodo.24055868","is_oa":true,"landing_page_url":"https://doi.org/10.5281/zenodo.24055868","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article-journal"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doi.org/10.5281/zenodo.24055868","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5161265887","display_name":"P. Jyosana Rani, I. Nagaraju, Dr. V.Anjaneyulum, G Vijaya Kumar","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"P. Jyosana Rani, I. Nagaraju, Dr. V.Anjaneyulum, G Vijaya Kumar","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5161265887"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10256","display_name":"Drug Solubulity and Delivery Systems","score":0.8788999915122986,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10256","display_name":"Drug Solubulity and Delivery Systems","score":0.8788999915122986,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.09730000048875809,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12547","display_name":"Pharmaceutical studies and practices","score":0.00430000014603138,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pomalidomide","display_name":"pomalidomide","score":0.9789999723434448},{"id":"https://openalex.org/keywords/hard-gelatin-capsules","display_name":"hard gelatin capsules","score":0.9380000233650208},{"id":"https://openalex.org/keywords/oral-drug-delivery","display_name":"oral drug delivery","score":0.9850000143051147},{"id":"https://openalex.org/keywords/capsule-formulation","display_name":"capsule formulation","score":0.8140000104904175},{"id":"https://openalex.org/keywords/in-vitro-drug-release","display_name":"in vitro drug release","score":0.9089999794960022},{"id":"https://openalex.org/keywords/dissolution","display_name":"dissolution","score":0.8159999847412109},{"id":"https://openalex.org/keywords/capsule-filling","display_name":"capsule filling","score":0.4009999930858612},{"id":"https://openalex.org/keywords/multiple-myeloma","display_name":"multiple myeloma","score":0.7549999952316284},{"id":"https://openalex.org/keywords/poorly-water-soluble-drugs","display_name":"poorly water-soluble drugs","score":0.824999988079071}],"concepts":[{"id":"https://openalex.org/C2778823387","wikidata":"https://www.wikidata.org/wiki/Q179254","display_name":"Gelatin","level":2,"score":0.9016000032424927},{"id":"https://openalex.org/C2778524551","wikidata":"https://www.wikidata.org/wiki/Q7227206","display_name":"Pomalidomide","level":4,"score":0.8276000022888184},{"id":"https://openalex.org/C2778778583","wikidata":"https://www.wikidata.org/wiki/Q147768","display_name":"Capsule","level":2,"score":0.6541000008583069},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.5156999826431274},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.49549999833106995},{"id":"https://openalex.org/C155574463","wikidata":"https://www.wikidata.org/wiki/Q170731","display_name":"Solubility","level":2,"score":0.4945000112056732},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.4733000099658966},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.46389999985694885},{"id":"https://openalex.org/C77281830","wikidata":"https://www.wikidata.org/wiki/Q718608","display_name":"Dosage form","level":2,"score":0.4503999948501587},{"id":"https://openalex.org/C2779820397","wikidata":"https://www.wikidata.org/wiki/Q1392806","display_name":"Drug delivery","level":2,"score":0.42149999737739563},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.375900000333786},{"id":"https://openalex.org/C45904493","wikidata":"https://www.wikidata.org/wiki/Q912807","display_name":"Active ingredient","level":2,"score":0.36039999127388},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.35089999437332153},{"id":"https://openalex.org/C88380143","wikidata":"https://www.wikidata.org/wiki/Q416674","display_name":"Dissolution","level":2,"score":0.31839999556541443},{"id":"https://openalex.org/C138651985","wikidata":"https://www.wikidata.org/wiki/Q186249","display_name":"Pharmaceutics","level":2,"score":0.3149999976158142},{"id":"https://openalex.org/C13245373","wikidata":"https://www.wikidata.org/wiki/Q3715494","display_name":"Drug carrier","level":3,"score":0.31470000743865967},{"id":"https://openalex.org/C2777239854","wikidata":"https://www.wikidata.org/wiki/Q902638","display_name":"Excipient","level":2,"score":0.3124000132083893},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3061000108718872},{"id":"https://openalex.org/C14029885","wikidata":"https://www.wikidata.org/wiki/Q5282807","display_name":"Dissolution testing","level":4,"score":0.2962999939918518},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.262800008058548}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.5281/zenodo.24055868","doi":"https://doi.org/10.5281/zenodo.24055868","is_oa":true,"landing_page_url":"https://doi.org/10.5281/zenodo.24055868","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article-journal"},{"id":"doi:10.5281/zenodo.24055869","doi":"https://doi.org/10.5281/zenodo.24055869","is_oa":true,"landing_page_url":"https://doi.org/10.5281/zenodo.24055869","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article-journal"}],"best_oa_location":{"id":"doi:10.5281/zenodo.24055868","doi":"https://doi.org/10.5281/zenodo.24055868","is_oa":true,"landing_page_url":"https://doi.org/10.5281/zenodo.24055868","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article-journal"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8371999859809875}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2741680656","https://openalex.org/W4415881359","https://openalex.org/W3010819870","https://openalex.org/W2410577884","https://openalex.org/W2433704805","https://openalex.org/W2790389656","https://openalex.org/W7159874831","https://openalex.org/W4323049373","https://openalex.org/W7128953497","https://openalex.org/W2137709143"],"abstract_inverted_index":{"The":[0,48,88,105,116,122,136,174],"present":[1],"study":[2,49,126],"was":[3],"undertaken":[4],"with":[5,134],"the":[6,28,154,157,203],"objective":[7],"of":[8,15,30,188],"formulating":[9],"and":[10,33,44,57,61,85,101,112,146,168,195,207],"evaluating":[11,58],"hard":[12,160],"gelatin":[13,67,161,212],"capsules":[14,68,117],"Pomalidomide":[16,21,70,159],"for":[17,93,185],"oral":[18,45,186],"drug":[19,132,141,215],"delivery.":[20],"is":[22],"an":[23],"immunomodulatory":[24],"agent":[25],"used":[26],"in":[27,62,102,123,131,170,196],"management":[29],"multiple":[31],"myeloma":[32],"possesses":[34],"challenging":[35],"aqueous":[36],"solubility":[37],"characteristics,":[38],"which":[39],"may":[40,177],"affect":[41],"its":[42,59],"dissolution":[43,125],"drug-release":[46,64,86,172],"behaviour.":[47],"focused":[50],"on":[51,153],"developing":[52],"a":[53,109,128,181],"suitable":[54,74],"capsule":[55,83,162],"formulation":[56,107,138,163,176],"physicochemical":[60],"vitro":[63,103,124,171],"characteristics.":[65,87,115,173],"Hard":[66,211],"containing":[69],"were":[71,91],"prepared":[72,89],"using":[73],"pharmaceutical":[75],"excipients":[76],"selected":[77],"to":[78,201],"provide":[79],"satisfactory":[80,113,119,165],"flow,":[81],"filling,":[82],"integrity,":[84],"formulations":[90],"evaluated":[92],"appearance,":[94],"weight":[95],"variation,":[96],"dimensions,":[97],"mechanical":[98,120],"strength,":[99],"friability,":[100],"dissolution.":[104],"optimized":[106,137,158],"showed":[108,139],"uniform":[110],"appearance":[111],"physical":[114,166],"exhibited":[118,164],"integrity.":[121],"demonstrated":[127],"progressive":[129],"increase":[130],"release":[133,142],"time.":[135],"84.16%":[140],"at":[143,149],"30":[144],"min":[145],"97.10":[147],"%":[148],"45":[150],"min.":[151],"Based":[152],"overall":[155],"evaluation,":[156],"properties":[167],"reproducible":[169],"developed":[175],"therefore":[178],"serve":[179],"as":[180],"promising":[182],"laboratory-scale":[183],"approach":[184],"delivery":[187],"Pomalidomide.":[189],"Further":[190],"studies":[191],"involving":[192],"stability,":[193],"scale-up,":[194],"vivo":[197],"evaluation":[198],"are":[199],"recommended":[200],"establish":[202],"formulation's":[204],"long-term":[205],"performance":[206],"suitability.":[208],"Keywords:":[209],"Pomalidomide;":[210],"capsule;":[213],"Oral":[214],"delivery;":[216],"Formulation":[217],"development;":[218],"Dissolution;":[219],"Drug":[220],"release;":[221],"Pharmaceutical":[222],"evaluation;":[223],"Weight":[224],"variation;":[225],"Mechanical":[226],"strength.":[227]},"counts_by_year":[],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2026-11-09T00:00:00"}