{"id":"https://openalex.org/W7225461986","doi":"https://doi.org/10.1016/j.indcrop.2026.124725","title":"Persimmon polysaccharide alleviates DSS-induced colitis in mice by restoring gut microbiota homeostasis and intestinal barrier function","display_name":"Persimmon polysaccharide alleviates DSS-induced colitis in mice by restoring gut microbiota homeostasis and intestinal barrier function","publication_year":2026,"publication_date":"2026-11-07","ids":{"openalex":"https://openalex.org/W7225461986","doi":"https://doi.org/10.1016/j.indcrop.2026.124725"},"language":"en","primary_location":{"id":"doi:10.1016/j.indcrop.2026.124725","doi":"https://doi.org/10.1016/j.indcrop.2026.124725","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.indcrop.2026.124725","pdf_url":null,"source":{"id":"https://openalex.org/S178362034","display_name":"Industrial Crops and Products","issn_l":"0926-6690","issn":["0926-6690","1872-633X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-2","ki-jl-1","norway-1","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Industrial Crops and Products","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1016/j.indcrop.2026.124725","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035693020","display_name":"Weijuan Han","orcid":"https://orcid.org/0000-0002-2032-3398","observed_orcids":["https://orcid.org/0000-0002-2032-3398"]},"institutions":[{"id":"https://openalex.org/I4210128615","display_name":"Chinese Academy of Forestry","ror":"https://ror.org/0360dkv71","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210128615","https://openalex.org/I4210134523"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Weijuan Han","raw_affiliation_strings":["Research Institute of Non-Timber Forestry, Chinese Academy of Forestry, Zhengzhou 450003, China"],"raw_orcid":"https://orcid.org/0000-0002-2032-3398","affiliations":[{"raw_affiliation_string":"Research Institute of Non-Timber Forestry, Chinese Academy of Forestry, Zhengzhou 450003, China","institution_ids":["https://openalex.org/I4210128615"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161194864","display_name":"Meng Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210128615","display_name":"Chinese Academy of Forestry","ror":"https://ror.org/0360dkv71","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210128615","https://openalex.org/I4210134523"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Meng Li","raw_affiliation_strings":["Research Institute of Non-Timber Forestry, Chinese Academy of Forestry, Zhengzhou 450003, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Institute of Non-Timber Forestry, Chinese Academy of Forestry, Zhengzhou 450003, China","institution_ids":["https://openalex.org/I4210128615"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161233776","display_name":"Yijun Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210128615","display_name":"Chinese Academy of Forestry","ror":"https://ror.org/0360dkv71","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210128615","https://openalex.org/I4210134523"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yijun Wang","raw_affiliation_strings":["Research Institute of Non-Timber Forestry, Chinese Academy of Forestry, Zhengzhou 450003, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Institute of Non-Timber Forestry, Chinese Academy of Forestry, Zhengzhou 450003, China","institution_ids":["https://openalex.org/I4210128615"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083268728","display_name":"Guo RongLin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210128615","display_name":"Chinese Academy of Forestry","ror":"https://ror.org/0360dkv71","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210128615","https://openalex.org/I4210134523"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ronglin Guo","raw_affiliation_strings":["Research Institute of Non-Timber Forestry, Chinese Academy of Forestry, Zhengzhou 450003, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Institute of Non-Timber Forestry, Chinese Academy of Forestry, Zhengzhou 450003, China","institution_ids":["https://openalex.org/I4210128615"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007036695","display_name":"Hua Li","orcid":"https://orcid.org/0000-0002-6798-6455","observed_orcids":["https://orcid.org/0000-0002-6798-6455"]},"institutions":[{"id":"https://openalex.org/I4210128615","display_name":"Chinese Academy of Forestry","ror":"https://ror.org/0360dkv71","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210128615","https://openalex.org/I4210134523"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Huawei Li","raw_affiliation_strings":["Research Institute of Non-Timber Forestry, Chinese Academy of Forestry, Zhengzhou 450003, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Institute of Non-Timber Forestry, Chinese Academy of Forestry, Zhengzhou 450003, China","institution_ids":["https://openalex.org/I4210128615"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102208932","display_name":"Man Gong","orcid":"https://orcid.org/0000-0002-9256-1213","observed_orcids":["https://orcid.org/0000-0002-9256-1213"]},"institutions":[{"id":"https://openalex.org/I160354188","display_name":"Henan University of Chinese Medicine","ror":"https://ror.org/01tsmvz08","country_code":"CN","type":"education","lineage":["https://openalex.org/I160354188"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Man Gong","raw_affiliation_strings":["Henan University of Chinese Medicine, 56 Jinshui East Road, Zhengzhou 450046, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Henan University of Chinese Medicine, 56 Jinshui East Road, Zhengzhou 450046, China","institution_ids":["https://openalex.org/I160354188"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161254286","display_name":"Yujing Suo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210128615","display_name":"Chinese Academy of Forestry","ror":"https://ror.org/0360dkv71","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210128615","https://openalex.org/I4210134523"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yujing Suo","raw_affiliation_strings":["Research Institute of Non-Timber Forestry, Chinese Academy of Forestry, Zhengzhou 450003, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Institute of Non-Timber Forestry, Chinese Academy of Forestry, Zhengzhou 450003, China","institution_ids":["https://openalex.org/I4210128615"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5124970205","display_name":"Peng Sun","orcid":"https://orcid.org/0000-0003-0355-2823","observed_orcids":["https://orcid.org/0000-0003-0355-2823"]},"institutions":[{"id":"https://openalex.org/I4210128615","display_name":"Chinese Academy of Forestry","ror":"https://ror.org/0360dkv71","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210128615","https://openalex.org/I4210134523"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Peng Sun","raw_affiliation_strings":["Research Institute of Non-Timber Forestry, Chinese Academy of Forestry, Zhengzhou 450003, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Institute of Non-Timber Forestry, Chinese Academy of Forestry, Zhengzhou 450003, China","institution_ids":["https://openalex.org/I4210128615"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5161230482","display_name":"Jianmin Fu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210128615","display_name":"Chinese Academy of Forestry","ror":"https://ror.org/0360dkv71","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210128615","https://openalex.org/I4210134523"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianmin Fu","raw_affiliation_strings":["Research Institute of Non-Timber Forestry, Chinese Academy of Forestry, Zhengzhou 450003, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Institute of Non-Timber Forestry, Chinese Academy of Forestry, Zhengzhou 450003, China","institution_ids":["https://openalex.org/I4210128615"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5007036695","https://openalex.org/A5102208932","https://openalex.org/A5161194864","https://openalex.org/A5161254286"],"corresponding_institution_ids":["https://openalex.org/I160354188","https://openalex.org/I4210128615"],"apc_list":{"value":3720,"currency":"USD","value_usd":3720},"apc_paid":{"value":3720,"currency":"USD","value_usd":3720},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"254","issue":null,"first_page":"124725","last_page":"124725"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10134","display_name":"Inflammatory Bowel Disease","score":0.9585000276565552,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10134","display_name":"Inflammatory Bowel Disease","score":0.9585000276565552,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.0272000003606081,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12489","display_name":"Microbial Metabolites in Food Biotechnology","score":0.0015999999595806003,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ulcerative-colitis","display_name":"ulcerative colitis","score":0.9760000109672546},{"id":"https://openalex.org/keywords/dss-induced-colitis","display_name":"DSS-induced colitis","score":0.9789999723434448},{"id":"https://openalex.org/keywords/gut-microbiota","display_name":"gut microbiota","score":0.9570000171661377},{"id":"https://openalex.org/keywords/intestinal-barrier-function","display_name":"intestinal barrier function","score":0.9760000109672546},{"id":"https://openalex.org/keywords/nlrp3-inflammasome","display_name":"NLRP3 inflammasome","score":0.9860000014305115},{"id":"https://openalex.org/keywords/pro-inflammatory-cytokines","display_name":"inflammatory cytokines","score":0.8830000162124634},{"id":"https://openalex.org/keywords/tight-junction-proteins","display_name":"tight junction proteins","score":0.9900000095367432},{"id":"https://openalex.org/keywords/goblet-cells","display_name":"goblet cells","score":0.8820000290870667},{"id":"https://openalex.org/keywords/fecal-microbiota-transplantation","display_name":"fecal microbiota transplantation","score":0.9369999766349792},{"id":"https://openalex.org/keywords/prebiotics","display_name":"prebiotics","score":0.921999990940094}],"concepts":[{"id":"https://openalex.org/C100817775","wikidata":"https://www.wikidata.org/wiki/Q134219","display_name":"Polysaccharide","level":2,"score":0.6539999842643738},{"id":"https://openalex.org/C2775862500","wikidata":"https://www.wikidata.org/wiki/Q2453464","display_name":"Colitis","level":2,"score":0.6498000025749207},{"id":"https://openalex.org/C51911345","wikidata":"https://www.wikidata.org/wiki/Q4863604","display_name":"Barrier function","level":2,"score":0.6373999714851379},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5745999813079834},{"id":"https://openalex.org/C539455810","wikidata":"https://www.wikidata.org/wiki/Q739734","display_name":"Gut flora","level":2,"score":0.5565000176429749},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.5490000247955322},{"id":"https://openalex.org/C63645605","wikidata":"https://www.wikidata.org/wiki/Q103191","display_name":"Homeostasis","level":2,"score":0.5029000043869019},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.3828999996185303},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.366100013256073},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.36399999260902405},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.322299987077713},{"id":"https://openalex.org/C3019368612","wikidata":"https://www.wikidata.org/wiki/Q17154506","display_name":"Intestinal mucosa","level":2,"score":0.3172999918460846},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3147999942302704},{"id":"https://openalex.org/C2778260677","wikidata":"https://www.wikidata.org/wiki/Q917447","display_name":"Inflammatory bowel disease","level":3,"score":0.3043999969959259},{"id":"https://openalex.org/C2780479503","wikidata":"https://www.wikidata.org/wiki/Q1477","display_name":"Ulcerative colitis","level":3,"score":0.2754000127315521},{"id":"https://openalex.org/C3018667095","wikidata":"https://www.wikidata.org/wiki/Q3455903","display_name":"Glucose homeostasis","level":4,"score":0.2648000121116638},{"id":"https://openalex.org/C2909812603","wikidata":"https://www.wikidata.org/wiki/Q739734","display_name":"Gut microflora","level":3,"score":0.25209999084472656}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.indcrop.2026.124725","doi":"https://doi.org/10.1016/j.indcrop.2026.124725","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.indcrop.2026.124725","pdf_url":null,"source":{"id":"https://openalex.org/S178362034","display_name":"Industrial Crops and Products","issn_l":"0926-6690","issn":["0926-6690","1872-633X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-2","ki-jl-1","norway-1","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Industrial Crops and Products","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/j.indcrop.2026.124725","doi":"https://doi.org/10.1016/j.indcrop.2026.124725","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.indcrop.2026.124725","pdf_url":null,"source":{"id":"https://openalex.org/S178362034","display_name":"Industrial Crops and Products","issn_l":"0926-6690","issn":["0926-6690","1872-633X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-2","ki-jl-1","norway-1","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Industrial Crops and Products","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":36,"referenced_works":["https://openalex.org/W2903362674","https://openalex.org/W4293424019","https://openalex.org/W4381620517","https://openalex.org/W4386954539","https://openalex.org/W4392213445","https://openalex.org/W4402450051","https://openalex.org/W4405983032","https://openalex.org/W4406314865","https://openalex.org/W4406605073","https://openalex.org/W4407080542","https://openalex.org/W4407386544","https://openalex.org/W4408530884","https://openalex.org/W4408991906","https://openalex.org/W4410023033","https://openalex.org/W4410933540","https://openalex.org/W4411000528","https://openalex.org/W4411025997","https://openalex.org/W4413086479","https://openalex.org/W4415671905","https://openalex.org/W4415929506","https://openalex.org/W4416419111","https://openalex.org/W4417349879","https://openalex.org/W4417501748","https://openalex.org/W7119485038","https://openalex.org/W7121558902","https://openalex.org/W7123350249","https://openalex.org/W7125410312","https://openalex.org/W7126072248","https://openalex.org/W7127367285","https://openalex.org/W7128783287","https://openalex.org/W7129739376","https://openalex.org/W7134055831","https://openalex.org/W7140108491","https://openalex.org/W7151221764","https://openalex.org/W7154988681","https://openalex.org/W7163740576"],"related_works":["https://openalex.org/W4407437502","https://openalex.org/W6998809842","https://openalex.org/W4387993805","https://openalex.org/W7212369994","https://openalex.org/W4392404246","https://openalex.org/W4225642159","https://openalex.org/W7140076681","https://openalex.org/W7134201559","https://openalex.org/W4379801148","https://openalex.org/W3196656695"],"abstract_inverted_index":{"Ulcerative":[0],"colitis":[1,54,90],"(UC)":[2],"is":[3,10,23],"a":[4,24,51],"chronic":[5],"inflammatory":[6],"bowel":[7],"condition,":[8],"which":[9],"linked":[11],"to":[12],"gut":[13],"microbiota":[14,111],"(GM)":[15],"imbalance":[16],"and":[17,26,48,59,70,86,88,99,105,141],"intestinal":[18],"barrier":[19,143],"(IB)":[20],"dysfunction.":[21],"Persimmon":[22],"medicinal":[25],"edible":[27],"fruit,":[28],"but":[29],"the":[30,107,115,121,126],"effects":[31,128],"of":[32,68,117],"persimmon":[33],"polysaccharides":[34],"(PPs)":[35],"on":[36],"UC":[37,134],"remain":[38],"unclear.":[39],"PPs":[40,57,79,93,132],"were":[41],"extracted":[42],"from":[43],"Zhongshi":[44],"No.":[45],"7,":[46],"characterized,":[47],"tested":[49],"in":[50],"DSS-induced":[52],"acute":[53],"mouse":[55],"model.":[56],"(150":[58],"300":[60],"mg/kg)":[61],"markedly":[62],"mitigated":[63],"body":[64],"weight":[65],"reduction,":[66],"elevation":[67],"DAI,":[69],"colon":[71],"length":[72],"reduction.":[73],"By":[74],"inhibiting":[75,138],"NLRP3":[76,139],"inflammasome":[77],"activation,":[78,140],"reduced":[80],"colonic":[81],"pro-inflammatory":[82],"cytokines":[83],"(TNF-\u03b1,":[84],"IL-6,":[85],"IL-1\u03b2)":[87],"relieved":[89],"symptoms.":[91],"Moreover,":[92],"upregulated":[94],"tight":[95],"junction":[96],"proteins":[97],"(Occludin":[98],"ZO-1),":[100],"increased":[101],"goblet":[102],"cell":[103],"numbers,":[104],"repaired":[106],"IB":[108],"function.":[109],"Fecal":[110],"transplantation":[112],"verified":[113],"that":[114,125],"transfer":[116],"PPs-modulated":[118],"GM":[119],"recapitulated":[120],"anti-colitis":[122],"effects,":[123],"demonstrating":[124],"protective":[127],"are":[129],"microbiota-dependent.":[130],"Overall,":[131],"alleviated":[133],"by":[135],"regulating":[136],"GM,":[137],"restoring":[142],"function,":[144],"supporting":[145],"its":[146],"exploitation":[147],"as":[148],"prebiotics.":[149]},"counts_by_year":[],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2026-11-08T00:00:00"}