{"id":"https://openalex.org/W7225457907","doi":"https://doi.org/10.55670/fpll.futech.5.4.28","title":"Assessment of somatic excitability and dendritic responses in a reduced conductance-based CA1 neuron model","display_name":"Assessment of somatic excitability and dendritic responses in a reduced conductance-based CA1 neuron model","publication_year":2026,"publication_date":"2026-11-08","ids":{"openalex":"https://openalex.org/W7225457907","doi":"https://doi.org/10.55670/fpll.futech.5.4.28"},"language":"en","primary_location":{"id":"doi:10.55670/fpll.futech.5.4.28","doi":"https://doi.org/10.55670/fpll.futech.5.4.28","is_oa":true,"landing_page_url":"https://doi.org/10.55670/fpll.futech.5.4.28","pdf_url":"https://fupubco.com/futech/article/download/1199/409/3032","source":{"id":"https://openalex.org/S4387279145","display_name":"Future Technology","issn_l":"2832-0379","issn":["2832-0379"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Future Technology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://fupubco.com/futech/article/download/1199/409/3032","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5161164967","display_name":"Youwang Yao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Youwang Yao","raw_affiliation_strings":["Department of Biomedical Engineering , Duke University , Durham , North Carolina , 27708 , USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering , Duke University , Durham , North Carolina , 27708 , USA","institution_ids":["https://openalex.org/I170897317"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5161164967"],"corresponding_institution_ids":["https://openalex.org/I170897317"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"5","issue":"4","first_page":"347","last_page":"360"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.7221999764442444,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.7221999764442444,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10502","display_name":"Advanced Memory and Neural Computing","score":0.17350000143051147,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10493","display_name":"Ion channel regulation and function","score":0.03660000115633011,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/spike-waveform","display_name":"spike waveform","score":0.5580000281333923},{"id":"https://openalex.org/keywords/interspike-intervals","display_name":"interspike intervals","score":0.6179999709129333},{"id":"https://openalex.org/keywords/a-current","display_name":"A-current","score":0.6209999918937683},{"id":"https://openalex.org/keywords/channel-kinetics","display_name":"channel kinetics","score":0.7070000171661377}],"concepts":[{"id":"https://openalex.org/C197424946","wikidata":"https://www.wikidata.org/wiki/Q1165717","display_name":"Waveform","level":3,"score":0.7081999778747559},{"id":"https://openalex.org/C180205008","wikidata":"https://www.wikidata.org/wiki/Q159190","display_name":"Amplitude","level":2,"score":0.6926000118255615},{"id":"https://openalex.org/C121932024","wikidata":"https://www.wikidata.org/wiki/Q5159376","display_name":"Conductance","level":2,"score":0.6079000234603882},{"id":"https://openalex.org/C2781390188","wikidata":"https://www.wikidata.org/wiki/Q25203449","display_name":"Spike (software development)","level":2,"score":0.5992000102996826},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5333999991416931},{"id":"https://openalex.org/C134305767","wikidata":"https://www.wikidata.org/wiki/Q725508","display_name":"Somatic cell","level":3,"score":0.4952000081539154},{"id":"https://openalex.org/C185263204","wikidata":"https://www.wikidata.org/wiki/Q1154774","display_name":"Electrophysiology","level":2,"score":0.492000013589859},{"id":"https://openalex.org/C2778468042","wikidata":"https://www.wikidata.org/wiki/Q273976","display_name":"Blockade","level":3,"score":0.414000004529953},{"id":"https://openalex.org/C50820595","wikidata":"https://www.wikidata.org/wiki/Q5256675","display_name":"Dendritic spike","level":4,"score":0.4097000062465668},{"id":"https://openalex.org/C47446073","wikidata":"https://www.wikidata.org/wiki/Q5165890","display_name":"Control theory (sociology)","level":3,"score":0.3935000002384186},{"id":"https://openalex.org/C195221683","wikidata":"https://www.wikidata.org/wiki/Q5000649","display_name":"Bursting","level":2,"score":0.3675000071525574},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.36649999022483826},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3564000129699707},{"id":"https://openalex.org/C127162648","wikidata":"https://www.wikidata.org/wiki/Q16858953","display_name":"Channel (broadcasting)","level":2,"score":0.3495999872684479},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.3483000099658966},{"id":"https://openalex.org/C186565885","wikidata":"https://www.wikidata.org/wiki/Q1651163","display_name":"Biological neuron model","level":3,"score":0.3375000059604645},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.3352000117301941},{"id":"https://openalex.org/C2778794669","wikidata":"https://www.wikidata.org/wiki/Q43054","display_name":"Neuron","level":2,"score":0.3336000144481659},{"id":"https://openalex.org/C2776401178","wikidata":"https://www.wikidata.org/wiki/Q12050496","display_name":"Feature (linguistics)","level":2,"score":0.31610000133514404},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3019999861717224},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.30160000920295715},{"id":"https://openalex.org/C147944092","wikidata":"https://www.wikidata.org/wiki/Q176366","display_name":"Patch clamp","level":3,"score":0.29660001397132874},{"id":"https://openalex.org/C2909946758","wikidata":"https://www.wikidata.org/wiki/Q194277","display_name":"Spike train","level":3,"score":0.2903999984264374},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2806999981403351},{"id":"https://openalex.org/C152478114","wikidata":"https://www.wikidata.org/wiki/Q660910","display_name":"Neurophysiology","level":2,"score":0.27970001101493835},{"id":"https://openalex.org/C207579572","wikidata":"https://www.wikidata.org/wiki/Q5141582","display_name":"Coincidence detection in neurobiology","level":4,"score":0.2623000144958496}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.55670/fpll.futech.5.4.28","doi":"https://doi.org/10.55670/fpll.futech.5.4.28","is_oa":true,"landing_page_url":"https://doi.org/10.55670/fpll.futech.5.4.28","pdf_url":"https://fupubco.com/futech/article/download/1199/409/3032","source":{"id":"https://openalex.org/S4387279145","display_name":"Future Technology","issn_l":"2832-0379","issn":["2832-0379"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Future Technology","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.55670/fpll.futech.5.4.28","doi":"https://doi.org/10.55670/fpll.futech.5.4.28","is_oa":true,"landing_page_url":"https://doi.org/10.55670/fpll.futech.5.4.28","pdf_url":"https://fupubco.com/futech/article/download/1199/409/3032","source":{"id":"https://openalex.org/S4387279145","display_name":"Future Technology","issn_l":"2832-0379","issn":["2832-0379"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Future Technology","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7225457907.pdf","grobid_xml":"https://content.openalex.org/works/W7225457907.grobid-xml"},"referenced_works_count":29,"referenced_works":["https://openalex.org/W1549050411","https://openalex.org/W1735445987","https://openalex.org/W1836848727","https://openalex.org/W1855000541","https://openalex.org/W1967324141","https://openalex.org/W1983945814","https://openalex.org/W1985940938","https://openalex.org/W2000509838","https://openalex.org/W2015062907","https://openalex.org/W2020104881","https://openalex.org/W2048528277","https://openalex.org/W2055568369","https://openalex.org/W2057426891","https://openalex.org/W2076524128","https://openalex.org/W2079671310","https://openalex.org/W2096916130","https://openalex.org/W2117120818","https://openalex.org/W2144925492","https://openalex.org/W2146831880","https://openalex.org/W2164649534","https://openalex.org/W2168779967","https://openalex.org/W3121299021","https://openalex.org/W3142183260","https://openalex.org/W4214775604","https://openalex.org/W4220897666","https://openalex.org/W4234546939","https://openalex.org/W4308592550","https://openalex.org/W4313892406","https://openalex.org/W4394875380"],"related_works":["https://openalex.org/W2091764801","https://openalex.org/W2276489613","https://openalex.org/W4210522601","https://openalex.org/W2106256974","https://openalex.org/W2057179329","https://openalex.org/W1968687601","https://openalex.org/W2079646310","https://openalex.org/W2009951703","https://openalex.org/W6889359288","https://openalex.org/W2042421964"],"abstract_inverted_index":{"A":[0],"reduced":[1,66,87],"conductance-based":[2],"model":[3],"was":[4],"assessed":[5],"through":[6],"somatic":[7],"excitability,":[8],"firing":[9,148],"dynamics,":[10],"and":[11,31,61,102,112,133,146],"dendritic":[12,63],"conductance":[13,65],"responses.":[14],"The":[15,131],"reported":[16,132],"baseline":[17],"spike":[18],"had":[19],"a":[20,25,32,76,123],"threshold":[21,96],"of":[22,28,34],"\u221236.5":[23],"mV,":[24,30,60],"baseline-to-peak":[26],"amplitude":[27,55,104],"115.1":[29],"half-width":[33],"0.93":[35],"ms.":[36],"At":[37],"8":[38],"\u00b5A/cm\u00b2,":[39],"ISIs":[40],"shortened":[41],"before":[42],"lengthening":[43],"by":[44,92],"17.8%":[45],"relative":[46],"to":[47,58,68,99,107,118],"the":[48,88,95,103,128,150],"minimum":[49],"interval.":[50],"Dendritic":[51],"A-current":[52],"blockade":[53],"increased":[54],"from":[56,97,105],"92.8":[57],"100.8":[59],"halving":[62],"Na\u207a":[64],"it":[67],"69.9":[69],"mV.":[70,109],"Two":[71],"new":[72],"numerical":[73],"experiments":[74],"used":[75],"complete":[77],"reference":[78,134],"implementation":[79],"with":[80],"published":[81],"channel":[82],"kinetics.":[83,140],"Joint":[84],"waveform":[85,144],"retuning":[86],"normalized":[89],"feature":[90],"error":[91],"84.7%,":[93],"shifting":[94],"-39.13":[98],"-49.36":[100],"mV":[101],"114.71":[106],"96.76":[108],"Matched":[110],"zero-M":[111],"increased-M":[113],"controls":[114],"linked":[115],"M-gate":[116],"availability":[117],"late":[119],"ISI":[120],"lengthening,":[121],"while":[122],"fixed":[124],"A-inactivation":[125],"gate":[126],"changed":[127],"early-interval":[129],"trajectory.":[130],"baselines":[135],"use":[136],"their":[137],"respective":[138],"specified":[139],"These":[141],"analyses":[142],"quantify":[143],"trade-offs":[145],"conductance-dependent":[147],"in":[149],"compact":[151],"representation.":[152]},"counts_by_year":[],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2026-11-08T00:00:00"}