{"id":"https://openalex.org/W7225448922","doi":"https://doi.org/10.1093/ofid/ofag731","title":"Hepatitis B Reactivation and Infection in People with HIV on Tenofovir-Sparing Antiretroviral Therapy","display_name":"Hepatitis B Reactivation and Infection in People with HIV on Tenofovir-Sparing Antiretroviral Therapy","publication_year":2026,"publication_date":"2026-11-06","ids":{"openalex":"https://openalex.org/W7225448922","doi":"https://doi.org/10.1093/ofid/ofag731"},"language":"en","primary_location":{"id":"doi:10.1093/ofid/ofag731","doi":"https://doi.org/10.1093/ofid/ofag731","is_oa":true,"landing_page_url":"https://doi.org/10.1093/ofid/ofag731","pdf_url":"https://academic.oup.com/ofid/advance-article-pdf/doi/10.1093/ofid/ofag731/73272004/ofag731.pdf","source":{"id":"https://openalex.org/S2735126445","display_name":"Open Forum Infectious Diseases","issn_l":"2328-8957","issn":["2328-8957"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Open Forum Infectious Diseases","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/ofid/advance-article-pdf/doi/10.1093/ofid/ofag731/73272004/ofag731.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5018125259","display_name":"Grace C. Haser","orcid":"https://orcid.org/0000-0002-8227-2557","observed_orcids":["https://orcid.org/0000-0002-8227-2557"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"G C Haser","raw_affiliation_strings":["University of California , San Francisco; San Francisco, CA ,"],"raw_orcid":"https://orcid.org/0000-0002-8227-2557","affiliations":[{"raw_affiliation_string":"University of California , San Francisco; San Francisco, CA ,","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161148523","display_name":"N E Lisha","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"N E Lisha","raw_affiliation_strings":["University of California , San Francisco; San Francisco, CA ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California , San Francisco; San Francisco, CA ,","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042226870","display_name":"H. Nina Kim","orcid":"https://orcid.org/0000-0001-6710-9666","observed_orcids":["https://orcid.org/0000-0001-6710-9666"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"H N Kim","raw_affiliation_strings":["University of Washington; \u00a0 Seattle, WA ,"],"raw_orcid":"https://orcid.org/0000-0001-6710-9666","affiliations":[{"raw_affiliation_string":"University of Washington; \u00a0 Seattle, WA ,","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161143345","display_name":"G Burkholder","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"G Burkholder","raw_affiliation_strings":["University of Alabama at Birmingham; \u00a0 Birmingham, AL ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Alabama at Birmingham; \u00a0 Birmingham, AL ,","institution_ids":["https://openalex.org/I32389192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043737054","display_name":"E.R Cachay","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"E R Cachay","raw_affiliation_strings":["University of California , San Diego; San Diego, CA ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California , San Diego; San Diego, CA ,","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161204514","display_name":"H M Crane","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"H M Crane","raw_affiliation_strings":["University of Washington; \u00a0 Seattle, WA ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Washington; \u00a0 Seattle, WA ,","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161220172","display_name":"J A C Delaney","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J A C Delaney","raw_affiliation_strings":["University of Washington; \u00a0 Seattle, WA ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Washington; \u00a0 Seattle, WA ,","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010483983","display_name":"Oluwaseun O Falade-Nwulia","orcid":"https://orcid.org/0000-0003-2321-2295","observed_orcids":["https://orcid.org/0000-0003-2321-2295"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"O Falade-Nwulia","raw_affiliation_strings":["Johns Hopkins University School of Medicine; \u00a0 Baltimore, MD ,"],"raw_orcid":"https://orcid.org/0000-0003-2321-2295","affiliations":[{"raw_affiliation_string":"Johns Hopkins University School of Medicine; \u00a0 Baltimore, MD ,","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161143621","display_name":"J Fleming","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I44580034","display_name":"Fenway Health","ror":"https://ror.org/04ztdzs79","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I44580034"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J Fleming","raw_affiliation_strings":["Fenway Health ; Boston, MA ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fenway Health ; Boston, MA ,","institution_ids":["https://openalex.org/I44580034"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077239845","display_name":"Mari M. Kitahata","orcid":"https://orcid.org/0000-0002-5410-7175","observed_orcids":["https://orcid.org/0000-0002-5410-7175"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M M Kitahata","raw_affiliation_strings":["University of Washington; \u00a0 Seattle, WA ,"],"raw_orcid":"https://orcid.org/0000-0002-5410-7175","affiliations":[{"raw_affiliation_string":"University of Washington; \u00a0 Seattle, WA ,","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161144529","display_name":"A C Pettit","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A C Pettit","raw_affiliation_strings":["Vanderbilt University Medical Center ; Nashville, TN ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vanderbilt University Medical Center ; Nashville, TN ,","institution_ids":["https://openalex.org/I901861585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023131290","display_name":"Sarah E. Rutstein","orcid":"https://orcid.org/0000-0002-1571-6576","observed_orcids":["https://orcid.org/0000-0002-1571-6576"]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S E Rutstein","raw_affiliation_strings":["University of North Carolina at Chapel Hill; \u00a0 Chapel Hill, NC ,"],"raw_orcid":"https://orcid.org/0000-0002-1571-6576","affiliations":[{"raw_affiliation_string":"University of North Carolina at Chapel Hill; \u00a0 Chapel Hill, NC ,","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161204603","display_name":"G Yendewa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"G Yendewa","raw_affiliation_strings":["Case Western Reserve University; \u00a0 Cleveland, OH ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Case Western Reserve University; \u00a0 Cleveland, OH ,","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111592285","display_name":"Annie F. Luetkemeyer","orcid":"https://orcid.org/0000-0003-0911-1578","observed_orcids":["https://orcid.org/0000-0003-0911-1578"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A F Luetkemeyer","raw_affiliation_strings":["University of California , San Francisco; San Francisco, CA ,"],"raw_orcid":"https://orcid.org/0000-0003-0911-1578","affiliations":[{"raw_affiliation_string":"University of California , San Francisco; San Francisco, CA ,","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5076401880","display_name":"K. A. Christopoulos","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"K A Christopoulos","raw_affiliation_strings":["University of California , San Francisco; San Francisco, CA ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California , San Francisco; San Francisco, CA ,","institution_ids":["https://openalex.org/I180670191"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5018125259"],"corresponding_institution_ids":["https://openalex.org/I180670191"],"apc_list":{"value":4053,"currency":"USD","value_usd":4053},"apc_paid":{"value":4053,"currency":"USD","value_usd":4053},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10340","display_name":"Hepatitis B Virus Studies","score":0.9800000190734863,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10340","display_name":"Hepatitis B Virus Studies","score":0.9800000190734863,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10151","display_name":"Hepatitis C virus research","score":0.004800000227987766,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10082","display_name":"HIV/AIDS Research and Interventions","score":0.0035000001080334187,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hepatitis-b-reactivation","display_name":"HBV reactivation","score":0.8569999933242798},{"id":"https://openalex.org/keywords/hepatitis-b","display_name":"hepatitis B","score":0.7829999923706055},{"id":"https://openalex.org/keywords/hiv","display_name":"HIV","score":0.8809999823570251},{"id":"https://openalex.org/keywords/hepatitis-b-surface-antigen","display_name":"hepatitis B surface antigen","score":0.5809999704360962},{"id":"https://openalex.org/keywords/hepatitis-b-surface-antibody","display_name":"hepatitis B surface antibody","score":0.8259999752044678},{"id":"https://openalex.org/keywords/liver-injury","display_name":"liver injury","score":0.640999972820282},{"id":"https://openalex.org/keywords/alanine-aminotransferase","display_name":"alanine aminotransferase","score":0.9139999747276306},{"id":"https://openalex.org/keywords/hepatitis-b-vaccination","display_name":"hepatitis B vaccination","score":0.7139999866485596}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9369999766349792},{"id":"https://openalex.org/C2781413609","wikidata":"https://www.wikidata.org/wiki/Q7308373","display_name":"Regimen","level":2,"score":0.7249000072479248},{"id":"https://openalex.org/C2780593183","wikidata":"https://www.wikidata.org/wiki/Q6844","display_name":"Hepatitis B virus","level":3,"score":0.6467000246047974},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.6017000079154968},{"id":"https://openalex.org/C2993143319","wikidata":"https://www.wikidata.org/wiki/Q583050","display_name":"Antiretroviral therapy","level":4,"score":0.5602999925613403},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.5217000246047974},{"id":"https://openalex.org/C2777382497","wikidata":"https://www.wikidata.org/wiki/Q6853","display_name":"Hepatitis B","level":2,"score":0.5026000142097473},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.47350001335144043},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.45500001311302185},{"id":"https://openalex.org/C22070199","wikidata":"https://www.wikidata.org/wiki/Q192995","display_name":"Vaccination","level":2,"score":0.44040000438690186},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.41130000352859497},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.39640000462532043},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.36629998683929443},{"id":"https://openalex.org/C2993512173","wikidata":"https://www.wikidata.org/wiki/Q846227","display_name":"Antiviral therapy","level":4,"score":0.334199994802475},{"id":"https://openalex.org/C2776175608","wikidata":"https://www.wikidata.org/wiki/Q418586","display_name":"Entecavir","level":5,"score":0.32429999113082886},{"id":"https://openalex.org/C179755657","wikidata":"https://www.wikidata.org/wiki/Q58702","display_name":"Mortality rate","level":2,"score":0.32409998774528503},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.32280001044273376},{"id":"https://openalex.org/C2776029263","wikidata":"https://www.wikidata.org/wiki/Q131742","display_name":"Hepatitis","level":2,"score":0.3091999888420105},{"id":"https://openalex.org/C2777869810","wikidata":"https://www.wikidata.org/wiki/Q422631","display_name":"Lamivudine","level":4,"score":0.29910001158714294},{"id":"https://openalex.org/C142462285","wikidata":"https://www.wikidata.org/wiki/Q2528140","display_name":"Viral load","level":3,"score":0.2912999987602234},{"id":"https://openalex.org/C2780727368","wikidata":"https://www.wikidata.org/wiki/Q1928978","display_name":"Viral disease","level":3,"score":0.2892000079154968},{"id":"https://openalex.org/C3020491458","wikidata":"https://www.wikidata.org/wiki/Q131742","display_name":"Chronic hepatitis","level":3,"score":0.2872999906539917},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.28700000047683716},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.28040000796318054},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.27239999175071716},{"id":"https://openalex.org/C761482","wikidata":"https://www.wikidata.org/wiki/Q118093","display_name":"Transmission (telecommunications)","level":2,"score":0.26179999113082886},{"id":"https://openalex.org/C2777351918","wikidata":"https://www.wikidata.org/wiki/Q421559","display_name":"Reverse-transcriptase inhibitor","level":5,"score":0.2606000006198883},{"id":"https://openalex.org/C500440147","wikidata":"https://www.wikidata.org/wiki/Q701216","display_name":"Pharmacotherapy","level":2,"score":0.25999999046325684},{"id":"https://openalex.org/C205545832","wikidata":"https://www.wikidata.org/wiki/Q17156455","display_name":"Young adult","level":2,"score":0.2587999999523163},{"id":"https://openalex.org/C2992872382","wikidata":"https://www.wikidata.org/wiki/Q305481","display_name":"Alanine aminotransferase","level":2,"score":0.2572000026702881}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1093/ofid/ofag731","doi":"https://doi.org/10.1093/ofid/ofag731","is_oa":true,"landing_page_url":"https://doi.org/10.1093/ofid/ofag731","pdf_url":"https://academic.oup.com/ofid/advance-article-pdf/doi/10.1093/ofid/ofag731/73272004/ofag731.pdf","source":{"id":"https://openalex.org/S2735126445","display_name":"Open Forum Infectious Diseases","issn_l":"2328-8957","issn":["2328-8957"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Open Forum Infectious Diseases","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1093/ofid/ofag731","doi":"https://doi.org/10.1093/ofid/ofag731","is_oa":true,"landing_page_url":"https://doi.org/10.1093/ofid/ofag731","pdf_url":"https://academic.oup.com/ofid/advance-article-pdf/doi/10.1093/ofid/ofag731/73272004/ofag731.pdf","source":{"id":"https://openalex.org/S2735126445","display_name":"Open Forum Infectious Diseases","issn_l":"2328-8957","issn":["2328-8957"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Open Forum Infectious Diseases","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G2122320390","display_name":null,"funder_award_id":"AI036219","funder_id":"https://openalex.org/F4320310281","funder_display_name":"Case Western Reserve University"},{"id":"https://openalex.org/G2483435703","display_name":null,"funder_award_id":"P30 AI 094189","funder_id":"https://openalex.org/F4320310145","funder_display_name":"Johns Hopkins University"},{"id":"https://openalex.org/G3040019378","display_name":null,"funder_award_id":"U01 DA036935","funder_id":"https://openalex.org/F4320310145","funder_display_name":"Johns Hopkins University"},{"id":"https://openalex.org/G3138949240","display_name":null,"funder_award_id":"P30AI073961","funder_id":"https://openalex.org/F4320309249","funder_display_name":"University of Miami"},{"id":"https://openalex.org/G3181090803","display_name":null,"funder_award_id":"P30AI027763","funder_id":"https://openalex.org/F4320332622","funder_display_name":"University of California, San Francisco"},{"id":"https://openalex.org/G4575219416","display_name":null,"funder_award_id":"R24 AI067039","funder_id":"https://openalex.org/F4320310094","funder_display_name":"University of Washington"},{"id":"https://openalex.org/G4610217253","display_name":null,"funder_award_id":"P30 AI036219","funder_id":"https://openalex.org/F4320310281","funder_display_name":"Case Western Reserve University"},{"id":"https://openalex.org/G5641387088","display_name":null,"funder_award_id":"P30 AI036214","funder_id":"https://openalex.org/F4320308573","funder_display_name":"Gilead Sciences"},{"id":"https://openalex.org/G6625095162","display_name":null,"funder_award_id":"P30 AI027757","funder_id":"https://openalex.org/F4320310094","funder_display_name":"University of Washington"},{"id":"https://openalex.org/G7364671334","display_name":null,"funder_award_id":"P30 AI50410","funder_id":"https://openalex.org/F4320310145","funder_display_name":"Johns Hopkins University"},{"id":"https://openalex.org/G7791962275","display_name":null,"funder_award_id":"AI027757","funder_id":"https://openalex.org/F4320310094","funder_display_name":"University of Washington"},{"id":"https://openalex.org/G7871313406","display_name":null,"funder_award_id":"P30 AI50410","funder_id":"https://openalex.org/F4320308573","funder_display_name":"Gilead Sciences"},{"id":"https://openalex.org/G9000868588","display_name":"Training in HIV Translational Research","funder_award_id":"T32AI060530","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320308573","display_name":"Gilead Sciences","ror":"https://ror.org/056546b03"},{"id":"https://openalex.org/F4320309151","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34"},{"id":"https://openalex.org/F4320309249","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92"},{"id":"https://openalex.org/F4320310094","display_name":"University of Washington","ror":"https://ror.org/00cvxb145"},{"id":"https://openalex.org/F4320310145","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95"},{"id":"https://openalex.org/F4320310281","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332622","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7225448922.pdf","grobid_xml":"https://content.openalex.org/works/W7225448922.grobid-xml"},"referenced_works_count":4,"referenced_works":["https://openalex.org/W7124429628","https://openalex.org/W7139082539","https://openalex.org/W7140285254","https://openalex.org/W7148254373"],"related_works":["https://openalex.org/W7162484119","https://openalex.org/W7162197803","https://openalex.org/W7140285254","https://openalex.org/W7217211456","https://openalex.org/W7172326230","https://openalex.org/W7203832850","https://openalex.org/W4414348053","https://openalex.org/W4416411823","https://openalex.org/W7006803201","https://openalex.org/W2943915871"],"abstract_inverted_index":{"Abstract":[0],"Background":[1],"As":[2],"more":[3],"people":[4],"with":[5,56,127,149,188],"HIV":[6],"(PWH)":[7],"transition":[8],"to":[9],"tenofovir":[10],"(TXF)-sparing":[11],"antiretroviral":[12],"therapy":[13],"(ART),":[14],"the":[15,41],"risk":[16,130],"of":[17,37,47,67,83,99,106,111,120],"hepatitis":[18],"B":[19],"virus":[20],"(HBV)":[21],"reactivation":[22],"(HBVr)":[23],"and":[24,64,118,143,216],"new":[25,71],"infection":[26,55],"(HBVi)":[27],"is":[28],"a":[29,34,102],"concern.":[30],"Methods":[31],"We":[32,80,95],"conducted":[33],"retrospective":[35],"study":[36],"5,776":[38],"PWH":[39],"in":[40,168,180,186],"Centers":[42],"for":[43,131,218],"AIDS":[44],"Research":[45],"Network":[46],"Integrated":[48],"Clinical":[49],"Systems":[50],"cohort":[51,141],"without":[52],"active":[53],"HBV":[54,72,78,135,207],"\u22651":[57],"TXF-sparing":[58,89,176,201],"ART":[59,90,148,177],"regimen":[60],"prescribed":[61],"after":[62],"5/1/2014":[63],"examined":[65],"episodes":[66],"HBVi/r":[68,84,100,174,184],"defined":[69,155],"as":[70,156,214],"surface":[73,136],"antigen":[74],"(HBsAg)":[75],"positivity":[76],"or":[77,211],"viremia.":[79],"calculated":[81],"rate":[82,110,119],"over":[85,101],"total":[86],"time":[87],"on":[88,147,175],"per":[91,115,124],"10,000":[92,116,125],"person-years.":[93],"Results":[94],"identified":[96],"17":[97],"cases":[98],"median":[103],"5.3":[104],"years":[105],"follow":[107],"up.":[108],"The":[109],"HBVi":[112,171],"was":[113,122,178],"3.9":[114],"person-years,":[117,126],"HBVr":[121],"6.0":[123],"possible":[128],"higher":[129],"those":[132,145],"who":[133],"were":[134,196],"antibody":[137],"(HBsAb)":[138],"negative":[139],"at":[140],"entry":[142],"among":[144],"not":[146,197],"no":[150],"anti-HBV":[151],"activity.":[152],"Liver":[153],"injury,":[154],"alanine":[157],"aminotransferase":[158],"lab":[159],"value":[160],"\u2265":[161],"100":[162],"U/L,":[163],"occurred":[164,185],"within":[165],"3":[166],"months":[167],"only":[169],"one":[170],"case.":[172],"Conclusions":[173],"rare":[179],"this":[181],"U.S.":[182],"cohort.":[183],"some":[187],"prior":[189],"HBsAb":[190],"positivity,":[191],"but":[192],"significant":[193],"hepatic":[194],"flares":[195],"observed.":[198],"When":[199],"starting":[200],"ART,":[202],"providers":[203],"should":[204],"check":[205],"complete":[206],"serologies,":[208],"offer":[209],"initial":[210],"additional":[212],"vaccination":[213],"needed,":[215],"monitor":[217],"potential":[219],"HBVi/r.":[220]},"counts_by_year":[],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2026-11-08T00:00:00"}