{"id":"https://openalex.org/W7225428838","doi":"https://doi.org/10.1186/s12917-026-06085-4","title":"Spatiotemporal analysis of caprine tuberculosis in Castilla y Le\u00f3n, Spain, 2011\u20132023: using molecular epidemiology to guide eradication efforts","display_name":"Spatiotemporal analysis of caprine tuberculosis in Castilla y Le\u00f3n, Spain, 2011\u20132023: using molecular epidemiology to guide eradication efforts","publication_year":2026,"publication_date":"2026-11-06","ids":{"openalex":"https://openalex.org/W7225428838","doi":"https://doi.org/10.1186/s12917-026-06085-4"},"language":"en","primary_location":{"id":"doi:10.1186/s12917-026-06085-4","doi":"https://doi.org/10.1186/s12917-026-06085-4","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12917-026-06085-4","pdf_url":null,"source":{"id":"https://openalex.org/S197820984","display_name":"BMC Veterinary Research","issn_l":"1746-6148","issn":["1746-6148"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Veterinary Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1186/s12917-026-06085-4","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113469561","display_name":"J. Dom\u00ednguez Ortega","orcid":"https://orcid.org/0000-0002-8317-5230","observed_orcids":["https://orcid.org/0000-0002-8317-5230"]},"institutions":[{"id":"https://openalex.org/I121748325","display_name":"Universidad Complutense de Madrid","ror":"https://ror.org/02p0gd045","country_code":"ES","type":"education","lineage":["https://openalex.org/I121748325"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Javier Ortega","raw_affiliation_strings":["VISAVET Health Surveillance Centre, Complutense University of Madrid, Madrid, 28040, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"VISAVET Health Surveillance Centre, Complutense University of Madrid, Madrid, 28040, Spain","institution_ids":["https://openalex.org/I121748325"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029253643","display_name":"\u00c1lvaro Roy","orcid":"https://orcid.org/0000-0002-1436-8012","observed_orcids":["https://orcid.org/0000-0002-1436-8012"]},"institutions":[{"id":"https://openalex.org/I121748325","display_name":"Universidad Complutense de Madrid","ror":"https://ror.org/02p0gd045","country_code":"ES","type":"education","lineage":["https://openalex.org/I121748325"]},{"id":"https://openalex.org/I2801357902","display_name":"Instituto de Salud Carlos III","ror":"https://ror.org/00ca2c886","country_code":"ES","type":"nonprofit","lineage":["https://openalex.org/I2801357902","https://openalex.org/I4387152914"]},{"id":"https://openalex.org/I4210104705","display_name":"Centro Nacional de Epidemiolog\u00eda","ror":"https://ror.org/01dd3fd62","country_code":"ES","type":"facility","lineage":["https://openalex.org/I2801357902","https://openalex.org/I4210104705","https://openalex.org/I4387152914"]},{"id":"https://openalex.org/I4210154894","display_name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Epidemiolog\u00eda y Salud P\u00fablica","ror":"https://ror.org/050q0kv47","country_code":"ES","type":"facility","lineage":["https://openalex.org/I2801357902","https://openalex.org/I4210115082","https://openalex.org/I4210154894","https://openalex.org/I4387152914"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"\u00c1lvaro Roy","raw_affiliation_strings":["National Centre for Epidemiology, Instituto de Salud Carlos III, Av. Monforte de Lemos 5, Madrid, 28029, Spain","Networked Biomedical Research Centre in Epidemiology and Public Health (CIBERESP), Madrid, Spain","VISAVET Health Surveillance Centre, Complutense University of Madrid, Madrid, 28040, Spain"],"raw_orcid":"https://orcid.org/0000-0002-1436-8012","affiliations":[{"raw_affiliation_string":"National Centre for Epidemiology, Instituto de Salud Carlos III, Av. Monforte de Lemos 5, Madrid, 28029, Spain","institution_ids":["https://openalex.org/I2801357902","https://openalex.org/I4210104705"]},{"raw_affiliation_string":"Networked Biomedical Research Centre in Epidemiology and Public Health (CIBERESP), Madrid, Spain","institution_ids":["https://openalex.org/I4210154894"]},{"raw_affiliation_string":"VISAVET Health Surveillance Centre, Complutense University of Madrid, Madrid, 28040, Spain","institution_ids":["https://openalex.org/I121748325"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043026570","display_name":"V\u00edctor Lorente-Leal","orcid":"https://orcid.org/0000-0003-4096-0885","observed_orcids":["https://orcid.org/0000-0003-4096-0885"]},"institutions":[{"id":"https://openalex.org/I121748325","display_name":"Universidad Complutense de Madrid","ror":"https://ror.org/02p0gd045","country_code":"ES","type":"education","lineage":["https://openalex.org/I121748325"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"V\u00edctor Lorente-Leal","raw_affiliation_strings":["Departamento de Gen\u00e9tica, Fisiolog\u00eda y Microbiolog\u00eda, Facultad de Ciencias Biol\u00f3gicas, Universidad Complutense de Madrid, Madrid, 28040, Spain","VISAVET Health Surveillance Centre, Complutense University of Madrid, Madrid, 28040, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Gen\u00e9tica, Fisiolog\u00eda y Microbiolog\u00eda, Facultad de Ciencias Biol\u00f3gicas, Universidad Complutense de Madrid, Madrid, 28040, Spain","institution_ids":["https://openalex.org/I121748325"]},{"raw_affiliation_string":"VISAVET Health Surveillance Centre, Complutense University of Madrid, Madrid, 28040, Spain","institution_ids":["https://openalex.org/I121748325"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026215310","display_name":"Pilar Pozo","orcid":"https://orcid.org/0000-0002-2003-2873","observed_orcids":["https://orcid.org/0000-0002-2003-2873"]},"institutions":[{"id":"https://openalex.org/I121748325","display_name":"Universidad Complutense de Madrid","ror":"https://ror.org/02p0gd045","country_code":"ES","type":"education","lineage":["https://openalex.org/I121748325"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Pilar Pozo","raw_affiliation_strings":["VISAVET Health Surveillance Centre, Complutense University of Madrid, Madrid, 28040, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"VISAVET Health Surveillance Centre, Complutense University of Madrid, Madrid, 28040, Spain","institution_ids":["https://openalex.org/I121748325"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101497607","display_name":"Carlos Alberto Velasco","orcid":"https://orcid.org/0000-0003-0190-4581","observed_orcids":["https://orcid.org/0000-0003-0190-4581"]},"institutions":[{"id":"https://openalex.org/I121748325","display_name":"Universidad Complutense de Madrid","ror":"https://ror.org/02p0gd045","country_code":"ES","type":"education","lineage":["https://openalex.org/I121748325"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Carlos Velasco","raw_affiliation_strings":["Department of Animal Health, Faculty of Veterinary Medicine, Complutense University of Madrid, Madrid, 28040, Spain","VISAVET Health Surveillance Centre, Complutense University of Madrid, Madrid, 28040, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Animal Health, Faculty of Veterinary Medicine, Complutense University of Madrid, Madrid, 28040, Spain","institution_ids":["https://openalex.org/I121748325"]},{"raw_affiliation_string":"VISAVET Health Surveillance Centre, Complutense University of Madrid, Madrid, 28040, Spain","institution_ids":["https://openalex.org/I121748325"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005670000","display_name":"Anna Grau","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210123620","display_name":"Junta de Castilla y Le\u00f3n","ror":"https://ror.org/02s8dab97","country_code":"ES","type":"government","lineage":["https://openalex.org/I4210123620"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Anna Grau","raw_affiliation_strings":["Direcci\u00f3n General de Producci\u00f3n Agr\u00edcola y Ganadera, Consejer\u00eda de Agricultura, Ganader\u00eda y Desarrollo Rural, de La Junta de Castilla y Le\u00f3n, Valladolid, 47014, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Direcci\u00f3n General de Producci\u00f3n Agr\u00edcola y Ganadera, Consejer\u00eda de Agricultura, Ganader\u00eda y Desarrollo Rural, de La Junta de Castilla y Le\u00f3n, Valladolid, 47014, Spain","institution_ids":["https://openalex.org/I4210123620"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070688187","display_name":"Jes\u00fas N\u00e1car","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210123620","display_name":"Junta de Castilla y Le\u00f3n","ror":"https://ror.org/02s8dab97","country_code":"ES","type":"government","lineage":["https://openalex.org/I4210123620"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Jes\u00fas N\u00e1car","raw_affiliation_strings":["Direcci\u00f3n General de Producci\u00f3n Agr\u00edcola y Ganadera, Consejer\u00eda de Agricultura, Ganader\u00eda y Desarrollo Rural, de La Junta de Castilla y Le\u00f3n, Valladolid, 47014, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Direcci\u00f3n General de Producci\u00f3n Agr\u00edcola y Ganadera, Consejer\u00eda de Agricultura, Ganader\u00eda y Desarrollo Rural, de La Junta de Castilla y Le\u00f3n, Valladolid, 47014, Spain","institution_ids":["https://openalex.org/I4210123620"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113616708","display_name":"Marisol L\u00f3pez","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Marisol L\u00f3pez","raw_affiliation_strings":["Servicio Territorial de Agricultura, Ganader\u00eda y Desarrollo Rural, \u00c1vila, 05001, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Servicio Territorial de Agricultura, Ganader\u00eda y Desarrollo Rural, \u00c1vila, 05001, Spain","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052189891","display_name":"Julio \u00c1lvarez","orcid":"https://orcid.org/0000-0002-8999-9417","observed_orcids":["https://orcid.org/0000-0002-8999-9417"]},"institutions":[{"id":"https://openalex.org/I121748325","display_name":"Universidad Complutense de Madrid","ror":"https://ror.org/02p0gd045","country_code":"ES","type":"education","lineage":["https://openalex.org/I121748325"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Julio \u00c1lvarez","raw_affiliation_strings":["Department of Animal Health, Faculty of Veterinary Medicine, Complutense University of Madrid, Madrid, 28040, Spain","VISAVET Health Surveillance Centre, Complutense University of Madrid, Madrid, 28040, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Animal Health, Faculty of Veterinary Medicine, Complutense University of Madrid, Madrid, 28040, Spain","institution_ids":["https://openalex.org/I121748325"]},{"raw_affiliation_string":"VISAVET Health Surveillance Centre, Complutense University of Madrid, Madrid, 28040, Spain","institution_ids":["https://openalex.org/I121748325"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018166200","display_name":"Beatriz Romero","orcid":"https://orcid.org/0000-0001-5263-1806","observed_orcids":["https://orcid.org/0000-0001-5263-1806","https://orcid.org/0009-0003-0432-247X"]},"institutions":[{"id":"https://openalex.org/I121748325","display_name":"Universidad Complutense de Madrid","ror":"https://ror.org/02p0gd045","country_code":"ES","type":"education","lineage":["https://openalex.org/I121748325"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Beatriz Romero","raw_affiliation_strings":["Department of Animal Health, Faculty of Veterinary Medicine, Complutense University of Madrid, Madrid, 28040, Spain","VISAVET Health Surveillance Centre, Complutense University of Madrid, Madrid, 28040, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Animal Health, Faculty of Veterinary Medicine, Complutense University of Madrid, Madrid, 28040, Spain","institution_ids":["https://openalex.org/I121748325"]},{"raw_affiliation_string":"VISAVET Health Surveillance Centre, Complutense University of Madrid, Madrid, 28040, Spain","institution_ids":["https://openalex.org/I121748325"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064412356","display_name":"Javier Bezos","orcid":"https://orcid.org/0000-0003-1913-0545","observed_orcids":["https://orcid.org/0000-0003-1913-0545"]},"institutions":[{"id":"https://openalex.org/I121748325","display_name":"Universidad Complutense de Madrid","ror":"https://ror.org/02p0gd045","country_code":"ES","type":"education","lineage":["https://openalex.org/I121748325"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Javier Bezos","raw_affiliation_strings":["Department of Animal Health, Faculty of Veterinary Medicine, Complutense University of Madrid, Madrid, 28040, Spain","VISAVET Health Surveillance Centre, Complutense University of Madrid, Madrid, 28040, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Animal Health, Faculty of Veterinary Medicine, Complutense University of Madrid, Madrid, 28040, Spain","institution_ids":["https://openalex.org/I121748325"]},{"raw_affiliation_string":"VISAVET Health Surveillance Centre, Complutense University of Madrid, Madrid, 28040, Spain","institution_ids":["https://openalex.org/I121748325"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5029253643"],"corresponding_institution_ids":["https://openalex.org/I121748325","https://openalex.org/I2801357902","https://openalex.org/I4210104705","https://openalex.org/I4210154894"],"apc_list":{"value":3190,"currency":"USD","value_usd":3190},"apc_paid":{"value":3190,"currency":"USD","value_usd":3190},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10038","display_name":"Tuberculosis Research and Epidemiology","score":0.9042999744415283,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10038","display_name":"Tuberculosis Research and Epidemiology","score":0.9042999744415283,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11560","display_name":"Animal Disease Management and Epidemiology","score":0.06260000169277191,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11316","display_name":"Mycobacterium research and diagnosis","score":0.01590000092983246,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/caprine-tuberculosis","display_name":"caprine tuberculosis","score":0.9990000128746033},{"id":"https://openalex.org/keywords/mycobacterium-caprae","display_name":"Mycobacterium caprae","score":0.8629999756813049},{"id":"https://openalex.org/keywords/mycobacterium-bovis","display_name":"Mycobacterium bovis","score":0.972000002861023},{"id":"https://openalex.org/keywords/goats","display_name":"goats","score":0.7250000238418579},{"id":"https://openalex.org/keywords/disease-hotspots","display_name":"disease hotspots","score":0.8550000190734863},{"id":"https://openalex.org/keywords/whole-genome-sequencing","display_name":"whole genome sequencing","score":0.7360000014305115},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphisms","display_name":"single nucleotide polymorphisms","score":0.8119999766349792},{"id":"https://openalex.org/keywords/genetic-clusters","display_name":"genetic groups","score":0.49399998784065247},{"id":"https://openalex.org/keywords/outbreak-source-tracking","display_name":"outbreak source tracking","score":0.5879999995231628},{"id":"https://openalex.org/keywords/herd-level-prevalence","display_name":"herd prevalence","score":0.7580000162124634},{"id":"https://openalex.org/keywords/castile-and-leon","display_name":"Castilla y Le\u00f3n","score":0.7929999828338623},{"id":"https://openalex.org/keywords/dairy-herds","display_name":"dairy herds","score":0.6159999966621399}],"concepts":[{"id":"https://openalex.org/C116675565","wikidata":"https://www.wikidata.org/wiki/Q3241045","display_name":"Outbreak","level":2,"score":0.7580999732017517},{"id":"https://openalex.org/C97669555","wikidata":"https://www.wikidata.org/wiki/Q4118435","display_name":"Molecular epidemiology","level":4,"score":0.6708999872207642},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.657800018787384},{"id":"https://openalex.org/C761482","wikidata":"https://www.wikidata.org/wiki/Q118093","display_name":"Transmission (telecommunications)","level":2,"score":0.5709999799728394},{"id":"https://openalex.org/C194775826","wikidata":"https://www.wikidata.org/wiki/Q209542","display_name":"Herd","level":2,"score":0.5522000193595886},{"id":"https://openalex.org/C2778497218","wikidata":"https://www.wikidata.org/wiki/Q133447","display_name":"Mycobacterium bovis","level":4,"score":0.5511000156402588},{"id":"https://openalex.org/C2781069245","wikidata":"https://www.wikidata.org/wiki/Q12204","display_name":"Tuberculosis","level":2,"score":0.5462999939918518},{"id":"https://openalex.org/C42972112","wikidata":"https://www.wikidata.org/wiki/Q170201","display_name":"Veterinary medicine","level":1,"score":0.5430999994277954},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.5153999924659729},{"id":"https://openalex.org/C164866538","wikidata":"https://www.wikidata.org/wiki/Q367351","display_name":"Cluster (spacecraft)","level":2,"score":0.48510000109672546},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.42739999294281006},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.392300009727478},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.38989999890327454},{"id":"https://openalex.org/C2780664029","wikidata":"https://www.wikidata.org/wiki/Q5282120","display_name":"Disease burden","level":3,"score":0.34380000829696655},{"id":"https://openalex.org/C2776353676","wikidata":"https://www.wikidata.org/wiki/Q182672","display_name":"Zoonosis","level":2,"score":0.3400999903678894},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.33340001106262207},{"id":"https://openalex.org/C139275648","wikidata":"https://www.wikidata.org/wiki/Q17134011","display_name":"SNP","level":5,"score":0.32519999146461487},{"id":"https://openalex.org/C138816342","wikidata":"https://www.wikidata.org/wiki/Q189603","display_name":"Public health","level":2,"score":0.3206000030040741},{"id":"https://openalex.org/C205649164","wikidata":"https://www.wikidata.org/wiki/Q1071","display_name":"Geography","level":0,"score":0.30630001425743103},{"id":"https://openalex.org/C134215735","wikidata":"https://www.wikidata.org/wiki/Q120997","display_name":"Flock","level":2,"score":0.30390000343322754},{"id":"https://openalex.org/C52991690","wikidata":"https://www.wikidata.org/wiki/Q1740042","display_name":"Culling","level":3,"score":0.27950000762939453},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.27090001106262207},{"id":"https://openalex.org/C2777975735","wikidata":"https://www.wikidata.org/wiki/Q130971","display_name":"Mycobacterium tuberculosis","level":3,"score":0.2632000148296356},{"id":"https://openalex.org/C81977670","wikidata":"https://www.wikidata.org/wiki/Q585259","display_name":"Genetic diversity","level":3,"score":0.26260000467300415},{"id":"https://openalex.org/C3018264790","wikidata":"https://www.wikidata.org/wiki/Q133447","display_name":"Bovine tuberculosis","level":5,"score":0.2556999921798706},{"id":"https://openalex.org/C186079640","wikidata":"https://www.wikidata.org/wiki/Q719602","display_name":"Prevalence","level":3,"score":0.2551000118255615},{"id":"https://openalex.org/C110121322","wikidata":"https://www.wikidata.org/wiki/Q865811","display_name":"Distribution (mathematics)","level":2,"score":0.25060001015663147}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1186/s12917-026-06085-4","doi":"https://doi.org/10.1186/s12917-026-06085-4","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12917-026-06085-4","pdf_url":null,"source":{"id":"https://openalex.org/S197820984","display_name":"BMC Veterinary Research","issn_l":"1746-6148","issn":["1746-6148"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Veterinary Research","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1186/s12917-026-06085-4","doi":"https://doi.org/10.1186/s12917-026-06085-4","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12917-026-06085-4","pdf_url":null,"source":{"id":"https://openalex.org/S197820984","display_name":"BMC Veterinary Research","issn_l":"1746-6148","issn":["1746-6148"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Veterinary Research","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9391000270843506,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320334923","display_name":"Instituto de Salud Carlos III","ror":"https://ror.org/00ca2c886"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3083171131","https://openalex.org/W2171041690","https://openalex.org/W7131334236","https://openalex.org/W3170292057","https://openalex.org/W4394603898","https://openalex.org/W4409187184","https://openalex.org/W2989578495","https://openalex.org/W4296393199","https://openalex.org/W2774900527","https://openalex.org/W2588830863"],"abstract_inverted_index":{"Caprine":[0],"tuberculosis":[1],"(cTB)":[2],"is":[3],"a":[4,32,47,120,196,252],"chronic":[5],"zoonotic":[6],"disease":[7],"primarily":[8],"caused":[9],"by":[10],"Mycobacterium":[11],"caprae":[12],"and":[13,49,70,118,132,144,180,230],"M.":[14,150],"bovis":[15,151],"affecting":[16],"mainly":[17,44],"goats,":[18,37],"but":[19,38],"also":[20],"other":[21],"mammalian":[22],"species,":[23],"including":[24],"humans.":[25],"Despite":[26],"its":[27],"epidemiological":[28,162],"significance,":[29],"Spain":[30],"lacks":[31],"national":[33],"eradication":[34,198,244],"programme":[35,81],"in":[36,62,82,94,98,168,172,189,192,219,233,246],"regional":[39],"efforts":[40],"have":[41],"been":[42],"implemented,":[43],"based":[45],"on":[46],"test":[48],"cull":[50],"strategy.":[51,254],"This":[52,184],"13-year":[53],"longitudinal":[54],"study":[55,138,185],"(2011\u20132023)":[56],"aimed":[57],"to":[58,65,71,96,101,195,241],"analyze":[59],"spatiotemporal":[60,227],"trends":[61],"cTB":[63,80,197],"distribution":[64],"assess":[66],"the":[67,77,88,102,112,115,137,148,173,178,181,187,216,224,235],"programme's":[68],"effectiveness":[69],"identify":[72],"persistent":[73,201],"'hot":[74],"spots'":[75],"of":[76,104,128,147,158,226,237],"disease.":[78],"The":[79],"Castilla":[83],"y":[84],"Le\u00f3n":[85],"has":[86],"reduced":[87],"apparent":[89],"herd":[90],"prevalence":[91,117,191],"from":[92],"5.5%":[93],"2011":[95],"1.1%":[97],"2023,":[99],"leading":[100],"declaration":[103],"several":[105],"provinces":[106],"(7/9)":[107],"as":[108],"cTB-free.":[109],"\u00c1vila":[110],"was":[111,176],"province":[113],"with":[114,160,204],"highest":[116],"contained":[119],"significant":[121],"(":[122],"p":[123],"<":[124],"0.001)":[125],"spatial":[126],"cluster":[127,179],"positive":[129],"dairy":[130],"herds":[131],"most":[133],"outbreaks":[134,206,240],"detected":[135],"during":[136],"period.":[139],"Whole":[140],"Genome":[141],"Sequencing":[142],"(WGS)":[143],"SNP":[145,231],"analysis":[146,232],"dominant":[149],"SB0121":[152],"genotype":[153],"identified":[154],"six":[155],"genetic":[156],"clusters":[157],"isolates":[159],"putative":[161],"relations":[163],"(\u2264":[164],"12":[165],"SNPs)":[166],"circulating":[167],"17":[169],"flocks":[170],"located":[171],"municipality":[174],"where":[175],"present":[177],"neighboring":[182],"municipality.":[183],"highlights":[186],"reduction":[188],"TB":[190,239],"goats":[193],"due":[194],"programme.":[199],"However,":[200],"high-risk":[202,248],"areas":[203,249],"recurrent":[205,238],"were":[207],"still":[208],"identified,":[209],"suggesting":[210],"that":[211],"local":[212],"transmission":[213],"continues":[214],"despite":[215],"overall":[217],"decline":[218],"prevalence.":[220],"For":[221],"this":[222],"reason,":[223],"integration":[225],"analysis,":[228],"WGS":[229],"tracking":[234],"sources":[236],"guide":[242],"targeted":[243],"measures":[245],"these":[247],"could":[250],"be":[251],"valuable":[253]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2026-11-07T00:00:00"}