{"id":"https://openalex.org/W7225427703","doi":"https://doi.org/10.1021/acsami.6c15983","title":"Decellularized Amniotic Membrane\u2013Mesenchymal Stem Cell Composite Enhances Corneal Repair via Mitochondrial Bioenergetics Restoration","display_name":"Decellularized Amniotic Membrane\u2013Mesenchymal Stem Cell Composite Enhances Corneal Repair via Mitochondrial Bioenergetics Restoration","publication_year":2026,"publication_date":"2026-11-06","ids":{"openalex":"https://openalex.org/W7225427703","doi":"https://doi.org/10.1021/acsami.6c15983","pmid":"https://pubmed.ncbi.nlm.nih.gov/42993601"},"language":"en","primary_location":{"id":"doi:10.1021/acsami.6c15983","doi":"https://doi.org/10.1021/acsami.6c15983","is_oa":false,"landing_page_url":"https://doi.org/10.1021/acsami.6c15983","pdf_url":null,"source":{"id":"https://openalex.org/S164001016","display_name":"ACS Applied Materials & Interfaces","issn_l":"1944-8244","issn":["1944-8244","1944-8252"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ACS Applied Materials & Interfaces","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101849136","display_name":"Xinlin Yan","orcid":"https://orcid.org/0000-0001-8767-6721","observed_orcids":["https://orcid.org/0000-0001-8767-6721"]},"institutions":[{"id":"https://openalex.org/I205237279","display_name":"Nankai University","ror":"https://ror.org/01y1kjr75","country_code":"CN","type":"education","lineage":["https://openalex.org/I205237279"]},{"id":"https://openalex.org/I4210145773","display_name":"Tianjin Medical University Eye Hospital","ror":"https://ror.org/04j2cfe69","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210145773"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xinlin Yan","raw_affiliation_strings":["Nankai University Optometry and Vision Science Institute , ,","Tianjin Eye Institute, Tianjin Eye Hospital , , ,"],"raw_orcid":"https://orcid.org/0000-0001-8767-6721","affiliations":[{"raw_affiliation_string":"Nankai University Optometry and Vision Science Institute , ,","institution_ids":["https://openalex.org/I205237279"]},{"raw_affiliation_string":"Tianjin Eye Institute, Tianjin Eye Hospital , , ,","institution_ids":["https://openalex.org/I4210145773"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024698987","display_name":"Guozhen Chen","orcid":"https://orcid.org/0000-0003-0034-6186","observed_orcids":["https://orcid.org/0000-0003-0034-6186"]},"institutions":[{"id":"https://openalex.org/I4210145773","display_name":"Tianjin Medical University Eye Hospital","ror":"https://ror.org/04j2cfe69","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210145773"]},{"id":"https://openalex.org/I5740404","display_name":"Tianjin Medical University","ror":"https://ror.org/02mh8wx89","country_code":"CN","type":"education","lineage":["https://openalex.org/I5740404"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guozhen Chen","raw_affiliation_strings":["Clinical College of Ophthalmology, Tianjin Medical University , ,","Tianjin Eye Institute, Tianjin Eye Hospital , , ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical College of Ophthalmology, Tianjin Medical University , ,","institution_ids":["https://openalex.org/I5740404"]},{"raw_affiliation_string":"Tianjin Eye Institute, Tianjin Eye Hospital , , ,","institution_ids":["https://openalex.org/I4210145773"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161001200","display_name":"Yi Guan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210145773","display_name":"Tianjin Medical University Eye Hospital","ror":"https://ror.org/04j2cfe69","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210145773"]},{"id":"https://openalex.org/I5740404","display_name":"Tianjin Medical University","ror":"https://ror.org/02mh8wx89","country_code":"CN","type":"education","lineage":["https://openalex.org/I5740404"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yi Guan","raw_affiliation_strings":["Clinical College of Ophthalmology, Tianjin Medical University , ,","Tianjin Eye Institute, Tianjin Eye Hospital , , ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical College of Ophthalmology, Tianjin Medical University , ,","institution_ids":["https://openalex.org/I5740404"]},{"raw_affiliation_string":"Tianjin Eye Institute, Tianjin Eye Hospital , , ,","institution_ids":["https://openalex.org/I4210145773"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161040636","display_name":"Jing Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210145773","display_name":"Tianjin Medical University Eye Hospital","ror":"https://ror.org/04j2cfe69","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210145773"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jing Li","raw_affiliation_strings":["Tianjin Eye Institute, Tianjin Eye Hospital , , ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tianjin Eye Institute, Tianjin Eye Hospital , , ,","institution_ids":["https://openalex.org/I4210145773"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027150383","display_name":"Yuchuan Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210145773","display_name":"Tianjin Medical University Eye Hospital","ror":"https://ror.org/04j2cfe69","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210145773"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuchuan Wang","raw_affiliation_strings":["Tianjin Eye Institute, Tianjin Eye Hospital , , ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tianjin Eye Institute, Tianjin Eye Hospital , , ,","institution_ids":["https://openalex.org/I4210145773"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161117946","display_name":"Shumei Yang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210145773","display_name":"Tianjin Medical University Eye Hospital","ror":"https://ror.org/04j2cfe69","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210145773"]},{"id":"https://openalex.org/I5740404","display_name":"Tianjin Medical University","ror":"https://ror.org/02mh8wx89","country_code":"CN","type":"education","lineage":["https://openalex.org/I5740404"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shumei Yang","raw_affiliation_strings":["Clinical College of Ophthalmology, Tianjin Medical University , ,","Tianjin Eye Institute, Tianjin Eye Hospital , , ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical College of Ophthalmology, Tianjin Medical University , ,","institution_ids":["https://openalex.org/I5740404"]},{"raw_affiliation_string":"Tianjin Eye Institute, Tianjin Eye Hospital , , ,","institution_ids":["https://openalex.org/I4210145773"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5161063972","display_name":"Xuan Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205237279","display_name":"Nankai University","ror":"https://ror.org/01y1kjr75","country_code":"CN","type":"education","lineage":["https://openalex.org/I205237279"]},{"id":"https://openalex.org/I4210145773","display_name":"Tianjin Medical University Eye Hospital","ror":"https://ror.org/04j2cfe69","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210145773"]},{"id":"https://openalex.org/I5740404","display_name":"Tianjin Medical University","ror":"https://ror.org/02mh8wx89","country_code":"CN","type":"education","lineage":["https://openalex.org/I5740404"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xuan Li","raw_affiliation_strings":["Clinical College of Ophthalmology, Tianjin Medical University , ,","Nankai University Optometry and Vision Science Institute , ,","Tianjin Eye Institute, Tianjin Eye Hospital , , ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical College of Ophthalmology, Tianjin Medical University , ,","institution_ids":["https://openalex.org/I5740404"]},{"raw_affiliation_string":"Nankai University Optometry and Vision Science Institute , ,","institution_ids":["https://openalex.org/I205237279"]},{"raw_affiliation_string":"Tianjin Eye Institute, Tianjin Eye Hospital , , ,","institution_ids":["https://openalex.org/I4210145773"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5161063972"],"corresponding_institution_ids":["https://openalex.org/I205237279","https://openalex.org/I4210145773","https://openalex.org/I5740404"],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11828","display_name":"Corneal Surgery and Treatments","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11828","display_name":"Corneal Surgery and Treatments","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.007799999788403511,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/corneal-alkali-burn","display_name":"corneal alkali burn","score":0.9070000052452087},{"id":"https://openalex.org/keywords/decellularized-amniotic-membrane","display_name":"decellularized amniotic membrane","score":0.9649999737739563},{"id":"https://openalex.org/keywords/bone-marrow-derived-mesenchymal-stem-cells","display_name":"bone marrow-derived mesenchymal stem cells","score":0.9620000123977661},{"id":"https://openalex.org/keywords/mitochondrial-bioenergetics","display_name":"mitochondrial bioenergetics","score":0.9240000247955322},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.8790000081062317},{"id":"https://openalex.org/keywords/oxidative-phosphorylation","display_name":"oxidative phosphorylation","score":0.7929999828338623},{"id":"https://openalex.org/keywords/corneal-neovascularization","display_name":"corneal neovascularization","score":0.9549999833106995},{"id":"https://openalex.org/keywords/corneal-fibrosis","display_name":"corneal fibrosis","score":0.9779999852180481},{"id":"https://openalex.org/keywords/keratitis","display_name":"keratitis","score":0.8709999918937683},{"id":"https://openalex.org/keywords/corneal-stroma","display_name":"corneal stroma","score":0.6069999933242798},{"id":"https://openalex.org/keywords/biocomposites","display_name":"biocomposites","score":0.5630000233650208}],"concepts":[{"id":"https://openalex.org/C190672674","wikidata":"https://www.wikidata.org/wiki/Q3866591","display_name":"Decellularization","level":3,"score":0.8016999959945679},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.729200005531311},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.5383999943733215},{"id":"https://openalex.org/C198826908","wikidata":"https://www.wikidata.org/wiki/Q1922379","display_name":"Mesenchymal stem cell","level":2,"score":0.5205000042915344},{"id":"https://openalex.org/C2778401633","wikidata":"https://www.wikidata.org/wiki/Q418661","display_name":"Malondialdehyde","level":3,"score":0.5121999979019165},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4790000021457672},{"id":"https://openalex.org/C100206155","wikidata":"https://www.wikidata.org/wiki/Q570714","display_name":"Bioenergetics","level":3,"score":0.47530001401901245},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.42640000581741333},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4146000146865845},{"id":"https://openalex.org/C2776882836","wikidata":"https://www.wikidata.org/wiki/Q168291","display_name":"Cornea","level":2,"score":0.41339999437332153},{"id":"https://openalex.org/C2780686511","wikidata":"https://www.wikidata.org/wiki/Q579361","display_name":"Corneal transplantation","level":3,"score":0.40459999442100525},{"id":"https://openalex.org/C48349386","wikidata":"https://www.wikidata.org/wiki/Q424361","display_name":"Reactive oxygen species","level":2,"score":0.39980000257492065},{"id":"https://openalex.org/C57600042","wikidata":"https://www.wikidata.org/wiki/Q227564","display_name":"Oxidative phosphorylation","level":2,"score":0.38530001044273376},{"id":"https://openalex.org/C16930146","wikidata":"https://www.wikidata.org/wiki/Q4381253","display_name":"Stromal cell","level":2,"score":0.3684000074863434},{"id":"https://openalex.org/C2778784160","wikidata":"https://www.wikidata.org/wiki/Q419130","display_name":"Peroxynitrite","level":4,"score":0.3483000099658966},{"id":"https://openalex.org/C28859421","wikidata":"https://www.wikidata.org/wiki/Q39572","display_name":"Mitochondrion","level":2,"score":0.31869998574256897},{"id":"https://openalex.org/C171056886","wikidata":"https://www.wikidata.org/wiki/Q193119","display_name":"Regeneration (biology)","level":2,"score":0.31450000405311584},{"id":"https://openalex.org/C2779389132","wikidata":"https://www.wikidata.org/wiki/Q1533033","display_name":"Stem-cell therapy","level":3,"score":0.2874999940395355},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.2784999907016754},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.27410000562667847},{"id":"https://openalex.org/C503630168","wikidata":"https://www.wikidata.org/wiki/Q178069","display_name":"Necrosis","level":2,"score":0.2727999985218048},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.2720000147819519},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.2718999981880188},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.26460000872612},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.2517000138759613}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1021/acsami.6c15983","doi":"https://doi.org/10.1021/acsami.6c15983","is_oa":false,"landing_page_url":"https://doi.org/10.1021/acsami.6c15983","pdf_url":null,"source":{"id":"https://openalex.org/S164001016","display_name":"ACS Applied Materials & Interfaces","issn_l":"1944-8244","issn":["1944-8244","1944-8252"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","ki-jl-1","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ACS Applied Materials & Interfaces","raw_type":"journal-article"},{"id":"pmid:42993601","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42993601","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ACS applied materials & interfaces","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320323021","display_name":"Nankai University","ror":"https://ror.org/01y1kjr75"},{"id":"https://openalex.org/F4320326709","display_name":"Tianjin Municipal Education Commission","ror":"https://ror.org/01z7y3r39"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":62,"referenced_works":["https://openalex.org/W389603040","https://openalex.org/W1964436457","https://openalex.org/W2034555062","https://openalex.org/W2053765200","https://openalex.org/W2059891246","https://openalex.org/W2062352025","https://openalex.org/W2075750165","https://openalex.org/W2089713875","https://openalex.org/W2592337799","https://openalex.org/W2754652285","https://openalex.org/W2755640463","https://openalex.org/W2758161665","https://openalex.org/W2807994952","https://openalex.org/W2890466350","https://openalex.org/W2904994313","https://openalex.org/W2957538743","https://openalex.org/W3015647166","https://openalex.org/W3036785650","https://openalex.org/W3094171306","https://openalex.org/W3107681025","https://openalex.org/W3113079980","https://openalex.org/W3135888539","https://openalex.org/W3161910723","https://openalex.org/W3165402533","https://openalex.org/W3190371810","https://openalex.org/W3199121869","https://openalex.org/W3215270815","https://openalex.org/W4200518011","https://openalex.org/W4206420021","https://openalex.org/W4223590994","https://openalex.org/W4224231278","https://openalex.org/W4225289741","https://openalex.org/W4289528160","https://openalex.org/W4296627096","https://openalex.org/W4306784334","https://openalex.org/W4310537601","https://openalex.org/W4310995357","https://openalex.org/W4313824271","https://openalex.org/W4315434761","https://openalex.org/W4321374287","https://openalex.org/W4365998097","https://openalex.org/W4376116437","https://openalex.org/W4381095281","https://openalex.org/W4386256201","https://openalex.org/W4386331643","https://openalex.org/W4386963799","https://openalex.org/W4387907285","https://openalex.org/W4399490232","https://openalex.org/W4400943388","https://openalex.org/W4401528175","https://openalex.org/W4402494962","https://openalex.org/W4402651752","https://openalex.org/W4403777928","https://openalex.org/W4404106076","https://openalex.org/W4410327604","https://openalex.org/W4410487999","https://openalex.org/W4410635236","https://openalex.org/W4412653208","https://openalex.org/W4414352319","https://openalex.org/W4414456830","https://openalex.org/W4415379171","https://openalex.org/W7124139387"],"related_works":["https://openalex.org/W4410635236","https://openalex.org/W1558661572","https://openalex.org/W2790734171","https://openalex.org/W2197419637","https://openalex.org/W3135888539","https://openalex.org/W389603040","https://openalex.org/W7104184233","https://openalex.org/W2352875609","https://openalex.org/W2890589849","https://openalex.org/W2094635846"],"abstract_inverted_index":{"Corneal":[0],"alkali":[1,62,153],"burn":[2],"causes":[3],"persistent":[4],"inflammation,":[5],"fibrosis,":[6],"neovascularization,":[7,82],"and":[8,16,51,81,86,89,92,108,111,155,162],"vision":[9],"impairment.":[10],"Although":[11],"amniotic":[12],"membrane":[13],"(AM)":[14],"transplantation":[15,67],"mesenchymal":[17],"stem":[18],"cell":[19],"(MSC)-based":[20],"therapies":[21],"have":[22],"shown":[23],"therapeutic":[24,54,149],"potential,":[25],"their":[26],"combined":[27],"application":[28],"as":[29,101,146],"a":[30,43,57,142,147],"tissue-engineered":[31],"construct":[32],"for":[33,151],"alkali-induced":[34],"corneal":[35,61,79,152],"injury":[36,154],"remains":[37],"insufficiently":[38],"explored.":[39],"Here,":[40],"we":[41],"developed":[42],"decellularized":[44,143],"AM-based":[45],"bone":[46],"marrow-derived":[47],"MSC":[48],"(BMSC)":[49],"composite":[50,75,124,145],"evaluated":[52],"its":[53,169],"effects":[55,132],"in":[56],"mouse":[58],"model":[59],"of":[60,159,164],"burn.":[63],"Compared":[64],"with":[65,129],"AM":[66],"or":[68],"subconjunctival":[69],"BMSC":[70],"injection":[71],"alone,":[72],"the":[73,123],"BMSC-AM":[74,96],"more":[76,130],"effectively":[77],"reduced":[78,104],"opacity":[80],"restored":[83,125],"epithelial":[84],"integrity":[85],"stromal":[87],"architecture,":[88],"suppressed":[90],"inflammatory":[91],"fibrotic":[93],"responses.":[94],"Moreover,":[95],"treatment":[97],"alleviated":[98],"oxidative":[99,127,165],"stress,":[100],"indicated":[102],"by":[103],"reactive":[105],"oxygen":[106],"species":[107],"malondialdehyde":[109],"accumulation":[110],"increased":[112],"total":[113],"antioxidant":[114],"capacity.":[115],"Seahorse":[116],"mitochondrial":[117,126,160],"stress":[118,166],"analysis":[119],"further":[120],"demonstrated":[121],"that":[122,157],"phosphorylation,":[128],"pronounced":[131],"at":[133],"14":[134],"days":[135],"after":[136],"injury.":[137],"Collectively,":[138],"this":[139],"study":[140],"establishes":[141],"AM-BMSC":[144],"biomaterial-assisted":[148],"platform":[150],"suggests":[156],"preservation":[158],"bioenergetics":[161],"attenuation":[163],"contribute":[167],"to":[168],"reparative":[170],"effects.":[171]},"counts_by_year":[],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2026-11-07T00:00:00"}