{"id":"https://openalex.org/W7225426982","doi":"https://doi.org/10.64898/2026.11.04.764143","title":"Genomic analysis of the Streptococcus anginosus group; taxonomic implications, evolutionary insights and clinical considerations","display_name":"Genomic analysis of the Streptococcus anginosus group; taxonomic implications, evolutionary insights and clinical considerations","publication_year":2026,"publication_date":"2026-11-06","ids":{"openalex":"https://openalex.org/W7225426982","doi":"https://doi.org/10.64898/2026.11.04.764143"},"language":"en","primary_location":{"id":"doi:10.64898/2026.11.04.764143","doi":"https://doi.org/10.64898/2026.11.04.764143","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.11.04.764143","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2026/11/06/2026.11.04.764143.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.biorxiv.org/content/biorxiv/early/2026/11/06/2026.11.04.764143.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102962031","display_name":"Andrea Coleman","orcid":"https://orcid.org/0000-0001-8101-1585","observed_orcids":["https://orcid.org/0000-0001-8101-1585"]},"institutions":[{"id":"https://openalex.org/I165143802","display_name":"The University of Queensland","ror":"https://ror.org/00rqy9422","country_code":"AU","type":"education","lineage":["https://openalex.org/I165143802"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Andrea Coleman","raw_affiliation_strings":["University of Queensland, The Frazer Institute, Herston, Queensland, Australia;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Queensland, The Frazer Institute, Herston, Queensland, Australia;","institution_ids":["https://openalex.org/I165143802"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161091802","display_name":"Joshua Liaw","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210167058","display_name":"Children's Health Queensland Hospital and Health Service","ror":"https://ror.org/02t3p7e85","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I1302211766","https://openalex.org/I2801244131","https://openalex.org/I4210167058"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Joshua Liaw","raw_affiliation_strings":["Queensland Children's Hospital, Brisbane, Queensland, Australia;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Queensland Children's Hospital, Brisbane, Queensland, Australia;","institution_ids":["https://openalex.org/I4210167058"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161047790","display_name":"Diana Maresco-Pennisi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165143802","display_name":"The University of Queensland","ror":"https://ror.org/00rqy9422","country_code":"AU","type":"education","lineage":["https://openalex.org/I165143802"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Diana Maresco-Pennisi","raw_affiliation_strings":["University of Queensland, The Frazer Institute, Herston, Queensland, Australia;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Queensland, The Frazer Institute, Herston, Queensland, Australia;","institution_ids":["https://openalex.org/I165143802"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5099852823","display_name":"Rylee Deehan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165143802","display_name":"The University of Queensland","ror":"https://ror.org/00rqy9422","country_code":"AU","type":"education","lineage":["https://openalex.org/I165143802"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Rylee Deehan","raw_affiliation_strings":["Australian Centre for Ecogenomics, University of Queensland, St Lucia, Queensland, Australia;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Australian Centre for Ecogenomics, University of Queensland, St Lucia, Queensland, Australia;","institution_ids":["https://openalex.org/I165143802"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053401736","display_name":"Patrick N. A. Harris","orcid":"https://orcid.org/0000-0002-2895-0345","observed_orcids":["https://orcid.org/0000-0002-2895-0345","https://orcid.org/0000-0002-4649-4013"]},"institutions":[{"id":"https://openalex.org/I165143802","display_name":"The University of Queensland","ror":"https://ror.org/00rqy9422","country_code":"AU","type":"education","lineage":["https://openalex.org/I165143802"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Patrick N.A. Harris","raw_affiliation_strings":["University of Queensland, The Frazer Institute, Herston, Queensland, Australia;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Queensland, The Frazer Institute, Herston, Queensland, Australia;","institution_ids":["https://openalex.org/I165143802"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045387538","display_name":"Anders Cervin","orcid":"https://orcid.org/0000-0002-3427-4312","observed_orcids":["https://orcid.org/0000-0002-3427-4312"]},"institutions":[{"id":"https://openalex.org/I165143802","display_name":"The University of Queensland","ror":"https://ror.org/00rqy9422","country_code":"AU","type":"education","lineage":["https://openalex.org/I165143802"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Anders Cervin","raw_affiliation_strings":["University of Queensland, The Frazer Institute, Herston, Queensland, Australia;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Queensland, The Frazer Institute, Herston, Queensland, Australia;","institution_ids":["https://openalex.org/I165143802"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109366971","display_name":"Oskar Edkins","orcid":"https://orcid.org/0009-0003-0724-530X","observed_orcids":["https://orcid.org/0009-0003-0724-530X"]},"institutions":[{"id":"https://openalex.org/I2800639112","display_name":"Townsville Hospital","ror":"https://ror.org/021zqhw10","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I1302211766","https://openalex.org/I2800639112","https://openalex.org/I2801244131"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Oskar Edkins","raw_affiliation_strings":["Townsville University Hospital, Townsville, Queensland, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Townsville University Hospital, Townsville, Queensland, Australia","institution_ids":["https://openalex.org/I2800639112"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029588486","display_name":"Julian Zaugg","orcid":"https://orcid.org/0000-0002-4919-1448","observed_orcids":["https://orcid.org/0000-0002-4919-1448"]},"institutions":[{"id":"https://openalex.org/I165143802","display_name":"The University of Queensland","ror":"https://ror.org/00rqy9422","country_code":"AU","type":"education","lineage":["https://openalex.org/I165143802"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Julian Zaugg","raw_affiliation_strings":["Australian Centre for Ecogenomics, University of Queensland, St Lucia, Queensland, Australia;"],"raw_orcid":"https://orcid.org/0000-0002-4919-1448","affiliations":[{"raw_affiliation_string":"Australian Centre for Ecogenomics, University of Queensland, St Lucia, Queensland, Australia;","institution_ids":["https://openalex.org/I165143802"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5012133125","display_name":"Seweryn Bialasiewicz","orcid":"https://orcid.org/0000-0001-9474-6943","observed_orcids":["https://orcid.org/0000-0001-9474-6943"]},"institutions":[{"id":"https://openalex.org/I165143802","display_name":"The University of Queensland","ror":"https://ror.org/00rqy9422","country_code":"AU","type":"education","lineage":["https://openalex.org/I165143802"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Seweryn Bialasiewicz","raw_affiliation_strings":["Australian Centre for Ecogenomics, University of Queensland, St Lucia, Queensland, Australia;"],"raw_orcid":"https://orcid.org/0000-0001-9474-6943","affiliations":[{"raw_affiliation_string":"Australian Centre for Ecogenomics, University of Queensland, St Lucia, Queensland, Australia;","institution_ids":["https://openalex.org/I165143802"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5012133125"],"corresponding_institution_ids":["https://openalex.org/I165143802"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11153","display_name":"Streptococcal Infections and Treatments","score":0.7670999765396118,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11153","display_name":"Streptococcal Infections and Treatments","score":0.7670999765396118,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.08640000224113464,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12167","display_name":"Bacterial Identification and Susceptibility Testing","score":0.052299998700618744,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/streptococcus-anginosus-group","display_name":"Streptococcus anginosus group","score":0.9959999918937683},{"id":"https://openalex.org/keywords/streptococcus-anginosus","display_name":"Streptococcus anginosus","score":0.9610000252723694},{"id":"https://openalex.org/keywords/streptococcus-intermedius","display_name":"Streptococcus intermedius","score":0.9900000095367432},{"id":"https://openalex.org/keywords/streptococcus-constellatus","display_name":"Streptococcus constellatus","score":1.0},{"id":"https://openalex.org/keywords/bacterial-taxonomy","display_name":"bacterial taxonomy","score":0.7080000042915344},{"id":"https://openalex.org/keywords/invasive-infections","display_name":"invasive infections","score":0.36800000071525574},{"id":"https://openalex.org/keywords/carbohydrate-utilization","display_name":"carbohydrate utilization","score":0.6809999942779541},{"id":"https://openalex.org/keywords/bacterial-evolution","display_name":"bacterial evolution","score":0.3330000042915344},{"id":"https://openalex.org/keywords/recombination","display_name":"recombination","score":0.4309999942779541},{"id":"https://openalex.org/keywords/mobilome","display_name":"mobilome","score":0.6169999837875366},{"id":"https://openalex.org/keywords/carbohydrate-active-enzymes","display_name":"carbohydrate-active enzymes","score":0.8169999718666077},{"id":"https://openalex.org/keywords/metabolic-profiling","display_name":"metabolite profiling","score":0.625}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8504999876022339},{"id":"https://openalex.org/C2910829522","wikidata":"https://www.wikidata.org/wiki/Q309538","display_name":"Streptococcus anginosus","level":4,"score":0.8151999711990356},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.6751000285148621},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.5526000261306763},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.5048999786376953},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.44690001010894775},{"id":"https://openalex.org/C15151743","wikidata":"https://www.wikidata.org/wiki/Q903778","display_name":"Metagenomics","level":3,"score":0.4207000136375427},{"id":"https://openalex.org/C90132467","wikidata":"https://www.wikidata.org/wiki/Q171184","display_name":"Phylogenetics","level":3,"score":0.4169999957084656},{"id":"https://openalex.org/C77434933","wikidata":"https://www.wikidata.org/wiki/Q4043440","display_name":"Multilocus sequence typing","level":4,"score":0.4117000102996826},{"id":"https://openalex.org/C24432333","wikidata":"https://www.wikidata.org/wiki/Q2068526","display_name":"Whole genome sequencing","level":4,"score":0.4034999907016754},{"id":"https://openalex.org/C84597430","wikidata":"https://www.wikidata.org/wiki/Q106227","display_name":"Locus (genetics)","level":3,"score":0.40070000290870667},{"id":"https://openalex.org/C193252679","wikidata":"https://www.wikidata.org/wiki/Q242125","display_name":"Phylogenetic tree","level":3,"score":0.3785000145435333},{"id":"https://openalex.org/C44465124","wikidata":"https://www.wikidata.org/wiki/Q713623","display_name":"Clade","level":4,"score":0.33559998869895935},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3296999931335449},{"id":"https://openalex.org/C2908643440","wikidata":"https://www.wikidata.org/wiki/Q132809","display_name":"Clostridiales","level":4,"score":0.328900009393692},{"id":"https://openalex.org/C51679486","wikidata":"https://www.wikidata.org/wiki/Q380546","display_name":"DNA sequencing","level":3,"score":0.3276999890804291},{"id":"https://openalex.org/C139275648","wikidata":"https://www.wikidata.org/wiki/Q17134011","display_name":"SNP","level":5,"score":0.3116999864578247},{"id":"https://openalex.org/C81977670","wikidata":"https://www.wikidata.org/wiki/Q585259","display_name":"Genetic diversity","level":3,"score":0.30820000171661377},{"id":"https://openalex.org/C61053724","wikidata":"https://www.wikidata.org/wiki/Q1154615","display_name":"Sequence analysis","level":3,"score":0.3050999939441681},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.3001999855041504},{"id":"https://openalex.org/C67905577","wikidata":"https://www.wikidata.org/wiki/Q215980","display_name":"Ribosomal RNA","level":3,"score":0.298799991607666},{"id":"https://openalex.org/C197754878","wikidata":"https://www.wikidata.org/wiki/Q80711","display_name":"Haplotype","level":4,"score":0.29789999127388},{"id":"https://openalex.org/C189206191","wikidata":"https://www.wikidata.org/wiki/Q222046","display_name":"Genomics","level":4,"score":0.2842000126838684}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.64898/2026.11.04.764143","doi":"https://doi.org/10.64898/2026.11.04.764143","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.11.04.764143","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2026/11/06/2026.11.04.764143.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.64898/2026.11.04.764143","doi":"https://doi.org/10.64898/2026.11.04.764143","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.11.04.764143","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2026/11/06/2026.11.04.764143.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G7003087799","display_name":"Harnessing the gut microbiome to improve stem cell transplant outcome.","funder_award_id":"2028610","funder_id":"https://openalex.org/F4320334705","funder_display_name":"National Health and Medical Research Council"}],"funders":[{"id":"https://openalex.org/F4320312688","display_name":"Children's Hospital Foundation","ror":"https://ror.org/03g60bf21"},{"id":"https://openalex.org/F4320334705","display_name":"National Health and Medical Research Council","ror":"https://ror.org/011kf5r70"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7225426982.pdf","grobid_xml":"https://content.openalex.org/works/W7225426982.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2050698381","https://openalex.org/W2287207169","https://openalex.org/W4245315281","https://openalex.org/W1989006367","https://openalex.org/W4319294301","https://openalex.org/W4284881776","https://openalex.org/W2168165431","https://openalex.org/W2036122079","https://openalex.org/W2134831138","https://openalex.org/W1915775167"],"abstract_inverted_index":{"Background:":[0],"The":[1,181],"Streptococcus":[2],"anginosus":[3,143,184,321],"group":[4],"(SAG)":[5],"(S.":[6,148,240],"anginosus,":[7,149,201],"S.":[8,11,134,142,150,152,155,193,200,242,244,279,320],"intermedius,":[9,241],"and":[10,32,62,74,101,109,113,125,154,174,286],"constellatus)":[12],"causes":[13],"serious,":[14],"potentially":[15],"life-threatening,":[16],"invasive":[17,59,119,222,258,306],"infections,":[18,61],"often":[19],"in":[20,197,231,293],"otherwise":[21],"healthy":[22],"individuals.":[23],"However,":[24],"the":[25,35,232,294,318],"group's":[26],"diversity":[27],"is":[28,309],"still":[29],"poorly":[30],"understood,":[31],"with":[33,72,76,192,209,270,317],"it,":[34],"ability":[36],"to":[37,199,257,324,337],"identify":[38],"prognostic":[39],"markers":[40],"of":[41,189,206,235,330],"severe":[42],"disease.":[43,223,259],"Methods:":[44],"Long-read":[45],"sequencing":[46],"produced":[47],"closed":[48],"genomes":[49,84],"for":[50,58,118,221,289],"29":[51],"isolates":[52,64],"from":[53,65,345],"25":[54],"patients":[55],"hospitalised":[56],"primarily":[57],"SAG":[60,83,305,308],"21":[63],"20":[66],"non-hospitalised":[67],"controls.":[68],"Genomes":[69],"were":[70,92],"classified":[71],"GTDB-Tk":[73,124],"combined":[75],"211":[77],"reference":[78],"genomes.":[79],"After":[80],"dereplication,":[81],"207":[82],"(38":[85],"isolate,":[86],"169":[87],"reference)":[88],"representing":[89],"206":[90],"strains":[91],"analysed":[93],"using:":[94],"GTDB":[95],"classification,":[96],"average":[97],"nucleotide":[98],"identity,":[99],"multi-marker":[100],"core-genome":[102,266],"SNP":[103,267],"phylogenies,":[104],"recombination-aware":[105],"analyses,":[106],"mobilome,":[107],"CAZyme":[108],"gapseq":[110],"metabolic":[111],"profiling,":[112],"lineage-aware":[114],"genome-wide":[115],"association":[116],"testing":[117],"phenotype.":[120],"Results:":[121],"Agreement":[122],"between":[123],"MALDI-TOF":[126,139],"taxonomic":[127],"classifications":[128],"was":[129,215,219,229,268],"low":[130],"(42.8%),":[131],"including":[132],"two":[133],"massiliensis":[135],"cases":[136],"mis-identified":[137],"by":[138],"as":[140,218,304],"SAG.":[141],"resolved":[144,164],"into":[145,167,327],"four":[146,182,331],"taxa":[147,185,234],"hominis,":[151],"whileyi":[153],"vaginalis).":[156],"Phylogenies":[157],"based":[158],"on":[159],"core":[160],"genome":[161],"single-nucleotide":[162],"polymorphisms":[163],"these":[165],"species":[166,300,322],"distinct":[168,332],"clades,":[169],"whereas":[170],"16S":[171],"rRNA":[172],"gene":[173,264],"multilocus":[175],"sequence":[176,207],"analysis":[177,277],"phylogenies":[178],"did":[179],"not.":[180],"ex-S.":[183],"showed":[186],"a":[187,248,283,290,328],"gradient":[188],"genomic":[190],"cohesion,":[191],"vaginalis":[194,280],"being":[195],"near-clonal,":[196],"contrast":[198],"which":[202,246],"shared":[203],"high":[204],"levels":[205],"ancestry":[208],"other":[210],"neighbouring":[211],"taxa.":[212,333],"Carbohydrate":[213],"utilisation":[214,227],"strongly":[216],"lineage-associated,":[217],"propensity":[220,239],"A":[224],"~15Kbp":[225],"glycosaminoglycan":[226,251],"locus":[228],"found":[230],"three":[233],"highest":[236],"disease":[237],"severity":[238],"constellatus,":[243],"whileyi)":[245],"predicts":[247],"direct":[249],"host":[250],"feeding":[252],"mechanism":[253],"that":[254],"may":[255,301],"contribute":[256],"No":[260],"single":[261],"functional":[262],"feature,":[263],"or":[265],"associated":[269],"invasiveness":[271],"however":[272],"after":[273],"lineage-adjustment.":[274],"Combined":[275],"feature":[276],"suggests":[278],"has":[281,287],"undergone":[282],"niche":[284],"restriction":[285],"evolved":[288],"primary":[291],"existence":[292],"female":[295],"urogenital":[296],"tract.":[297],"Conclusions:":[298],"Under-reported":[299],"be":[302,325,338],"mis-diagnosed":[303],"infections.":[307],"more":[310],"diverse":[311],"than":[312,344],"its":[313],"current":[314],"three-species":[315],"definition,":[316],"conventional":[319],"proposed":[323],"classed":[326],"complex":[329],"Invasive":[334],"capacity":[335],"appears":[336],"an":[339],"emergent":[340],"system-level":[341],"property":[342],"rather":[343],"individual":[346],"features.":[347]},"counts_by_year":[],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2026-11-07T00:00:00"}