{"id":"https://openalex.org/W7225419973","doi":"https://doi.org/10.1111/jjns.70088","title":"Pathophysiology Education Using a Pamphlet Among Early School\u2010Age Children With Food Allergies: An Exploratory Pilot Controlled Study","display_name":"Pathophysiology Education Using a Pamphlet Among Early School\u2010Age Children With Food Allergies: An Exploratory Pilot Controlled Study","publication_year":2026,"publication_date":"2026-11-06","ids":{"openalex":"https://openalex.org/W7225419973","doi":"https://doi.org/10.1111/jjns.70088","pmid":"https://pubmed.ncbi.nlm.nih.gov/42990068","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13741121"},"language":"en","primary_location":{"id":"doi:10.1111/jjns.70088","doi":"https://doi.org/10.1111/jjns.70088","is_oa":true,"landing_page_url":"https://doi.org/10.1111/jjns.70088","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jjns.70088","source":{"id":"https://openalex.org/S116400863","display_name":"Japan Journal of Nursing Science","issn_l":"1742-7924","issn":["1742-7924","1742-7932"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Japan Journal of Nursing Science","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jjns.70088","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108738680","display_name":"Yoshiko Matsumoto","orcid":"https://orcid.org/0009-0001-1096-4263","observed_orcids":["https://orcid.org/0009-0001-1096-4263"]},"institutions":[{"id":"https://openalex.org/I42766147","display_name":"University of Toyama","ror":"https://ror.org/0445phv87","country_code":"JP","type":"education","lineage":["https://openalex.org/I42766147"]},{"id":"https://openalex.org/I63216439","display_name":"Toyama Prefectural University","ror":"https://ror.org/03xgh2v50","country_code":"JP","type":"education","lineage":["https://openalex.org/I63216439"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Yoshiko Matsumoto","raw_affiliation_strings":["Department of Pediatric Nursing Faculty of Nursing Toyama Prefectural University  Toyama Japan"],"raw_orcid":"https://orcid.org/0009-0001-1096-4263","affiliations":[{"raw_affiliation_string":"Department of Pediatric Nursing Faculty of Nursing Toyama Prefectural University  Toyama Japan","institution_ids":["https://openalex.org/I42766147","https://openalex.org/I63216439"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108474520","display_name":"Tomomi Hasegawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I42766147","display_name":"University of Toyama","ror":"https://ror.org/0445phv87","country_code":"JP","type":"education","lineage":["https://openalex.org/I42766147"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tomomi Hasegawa","raw_affiliation_strings":["Department of Maternity Nursing, Faculty of Medicine University of Toyama  Toyama Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Maternity Nursing, Faculty of Medicine University of Toyama  Toyama Japan","institution_ids":["https://openalex.org/I42766147"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5108738680"],"corresponding_institution_ids":["https://openalex.org/I42766147","https://openalex.org/I63216439"],"apc_list":{"value":2890,"currency":"USD","value_usd":2890},"apc_paid":{"value":2890,"currency":"USD","value_usd":2890},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"24","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10634","display_name":"Food Allergy and Anaphylaxis Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10634","display_name":"Food Allergy and Anaphylaxis Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12538","display_name":"Eosinophilic Esophagitis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11117","display_name":"Drug-Induced Adverse Reactions","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/food-allergy","display_name":"food allergy","score":0.9729999899864197},{"id":"https://openalex.org/keywords/pathophysiology-education","display_name":"pathophysiology education","score":0.9459999799728394},{"id":"https://openalex.org/keywords/educational-leaflets","display_name":"educational pamphlets","score":0.6019999980926514},{"id":"https://openalex.org/keywords/individual-instruction","display_name":"individual instruction","score":0.8939999938011169},{"id":"https://openalex.org/keywords/younger-schoolchildren","display_name":"younger schoolchildren","score":0.8159999847412109},{"id":"https://openalex.org/keywords/oral-food-challenge","display_name":"oral food challenge","score":0.8700000047683716},{"id":"https://openalex.org/keywords/mast-cells","display_name":"mast cells","score":0.777999997138977},{"id":"https://openalex.org/keywords/patient-education","display_name":"patient education","score":0.5569999814033508},{"id":"https://openalex.org/keywords/health-literacy","display_name":"health literacy","score":0.48899999260902405},{"id":"https://openalex.org/keywords/quality-of-life","display_name":"quality of life","score":0.7310000061988831}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7276999950408936},{"id":"https://openalex.org/C27415008","wikidata":"https://www.wikidata.org/wiki/Q7256382","display_name":"Psychological intervention","level":2,"score":0.6534000039100647},{"id":"https://openalex.org/C2776027960","wikidata":"https://www.wikidata.org/wiki/Q769815","display_name":"Food allergy","level":3,"score":0.5584999918937683},{"id":"https://openalex.org/C85973986","wikidata":"https://www.wikidata.org/wiki/Q1091731","display_name":"Exploratory research","level":2,"score":0.5034000277519226},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.4388999938964844},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.4000000059604645},{"id":"https://openalex.org/C3018260909","wikidata":"https://www.wikidata.org/wiki/Q1322871","display_name":"Exploratory analysis","level":2,"score":0.36970001459121704},{"id":"https://openalex.org/C100480397","wikidata":"https://www.wikidata.org/wiki/Q7836899","display_name":"Treatment and control groups","level":2,"score":0.35760000348091125},{"id":"https://openalex.org/C207480886","wikidata":"https://www.wikidata.org/wiki/Q42982","display_name":"Allergy","level":2,"score":0.3508000075817108},{"id":"https://openalex.org/C512399662","wikidata":"https://www.wikidata.org/wiki/Q3505712","display_name":"Family medicine","level":1,"score":0.32190001010894775},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.3010999858379364},{"id":"https://openalex.org/C89611455","wikidata":"https://www.wikidata.org/wiki/Q6804646","display_name":"Mechanism (biology)","level":2,"score":0.3005000054836273},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.2955999970436096},{"id":"https://openalex.org/C2780665704","wikidata":"https://www.wikidata.org/wiki/Q959298","display_name":"Intervention (counseling)","level":2,"score":0.28220000863075256},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.257999986410141}],"mesh":[{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005512","descriptor_name":"Food Hypersensitivity","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010865","descriptor_name":"Pilot Projects","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1111/jjns.70088","doi":"https://doi.org/10.1111/jjns.70088","is_oa":true,"landing_page_url":"https://doi.org/10.1111/jjns.70088","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jjns.70088","source":{"id":"https://openalex.org/S116400863","display_name":"Japan Journal of Nursing Science","issn_l":"1742-7924","issn":["1742-7924","1742-7932"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Japan Journal of Nursing Science","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13741121","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13741121/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13741121/pdf/JJNS-24-e70088.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Jpn J Nurs Sci","raw_type":"Text"},{"id":"pmid:42990068","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42990068","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Japan journal of nursing science : JJNS","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1111/jjns.70088","doi":"https://doi.org/10.1111/jjns.70088","is_oa":true,"landing_page_url":"https://doi.org/10.1111/jjns.70088","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jjns.70088","source":{"id":"https://openalex.org/S116400863","display_name":"Japan Journal of Nursing Science","issn_l":"1742-7924","issn":["1742-7924","1742-7932"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Japan Journal of Nursing Science","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9763000011444092},{"display_name":"Quality education","id":"https://metadata.un.org/sdg/4","score":0.6164000034332275}],"study_designs":[{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7225419973.pdf","grobid_xml":"https://content.openalex.org/works/W7225419973.grobid-xml"},"referenced_works_count":17,"referenced_works":["https://openalex.org/W2007706875","https://openalex.org/W2047316668","https://openalex.org/W2068551904","https://openalex.org/W2084342166","https://openalex.org/W2108061745","https://openalex.org/W2112011443","https://openalex.org/W2548862769","https://openalex.org/W2626146763","https://openalex.org/W2891581756","https://openalex.org/W3021408699","https://openalex.org/W4285394033","https://openalex.org/W4378714220","https://openalex.org/W4380872085","https://openalex.org/W4389057996","https://openalex.org/W4400655804","https://openalex.org/W4402991945","https://openalex.org/W4412573359"],"related_works":["https://openalex.org/W1981468223","https://openalex.org/W3119264530","https://openalex.org/W2911869546","https://openalex.org/W2260639672","https://openalex.org/W3126243312","https://openalex.org/W2001075180","https://openalex.org/W4210612919","https://openalex.org/W4386253848","https://openalex.org/W4322757231","https://openalex.org/W1605506595"],"abstract_inverted_index":{"AIM:":[0],"To":[1],"evaluate":[2],"whether":[3],"individual":[4,86,131,167,198],"instruction":[5,87,132,168,199],"using":[6,228],"a":[7],"pamphlet,":[8],"compared":[9,212],"with":[10,46,197,213],"pamphlet":[11,84,129,165,195,214],"distribution":[12,215],"alone,":[13],"improves":[14],"the":[15,73,76,83,128,148,156,160,164,173,180],"understanding":[16,104],"of":[17,75,105,220],"food":[18,47,53,78,209],"allergy":[19,210],"pathophysiology":[20],"among":[21],"early":[22,43],"school-age":[23,44],"children":[24,45],"in":[25],"grades":[26],"1-3":[27],"(typically":[28],"aged":[29],"6-9":[30],"years).":[31],"METHODS:":[32],"A":[33,194],"non-randomized":[34],"exploratory":[35],"pilot":[36],"controlled":[37],"study":[38],"was":[39,110],"conducted":[40],"involving":[41],"46":[42],"allergies":[48],"who":[49],"were":[50,68,188],"undergoing":[51],"oral":[52,77],"challenges":[54],"(mean":[55],"age":[56],"=":[57,90,95,101],"7.11":[58],"\u00b1":[59],"0.79":[60],"years;":[61],"30":[62],"girls":[63],"and":[64,97,108,120,139,150,179],"16":[65],"boys).":[66],"Participants":[67],"assigned":[69],"sequentially":[70],"according":[71],"to":[72,80,233],"order":[74],"challenge":[79],"three":[81],"groups:":[82],"+":[85,130,166],"group":[88,93,99,169,175],"(n":[89,94,100],"15),":[91],"pamphlet-only":[92,174],"14),":[96],"control":[98],"17).":[102],"Self-reported":[103],"selected":[106,208],"terms":[107],"mechanisms":[109],"assessed":[111],"thrice:":[112],"once":[113],"before":[114],"(T1),":[115],"follow-ups":[116],"each":[117],"immediately":[118,146],"(T2),":[119],"1":[121],"month":[122],"(T3)":[123],"after":[124,147],"post-intervention.":[125],"RESULTS:":[126],"In":[127],"group,":[133],"scores":[134],"for":[135,176,190,207],"mast":[136,177,181],"cell,":[137],"immunity,":[138],"both":[140,221],"mechanism":[141,183],"items":[142],"improved":[143],"from":[144],"baseline":[145],"intervention,":[149],"these":[151],"improvements":[152],"remained":[153],"significant":[154,186],"at":[155],"one-month":[157,218],"follow-up.":[158],"At":[159],"immediate":[161,204],"post-intervention":[162],"assessment,":[163],"scored":[170],"higher":[171],"than":[172],"cell":[178],"cell-related":[182],"item.":[184,225],"No":[185],"effects":[187,219],"observed":[189],"quality-of-life":[191],"scores.":[192],"CONCLUSIONS:":[193],"combined":[196],"may":[200],"provide":[201],"an":[202],"additional":[203],"educational":[205],"benefit":[206],"concepts":[211],"alone.":[216],"The":[217],"interventions":[222],"varied":[223],"by":[224],"Larger":[226],"studies":[227],"validated":[229],"measures":[230],"are":[231],"needed":[232],"confirm":[234],"efficacy.":[235],"TRIAL":[236],"REGISTRATION:":[237],"Network":[238],"Clinical":[239],"Trials":[240],"Registry":[241],"(UMIN-CTR).":[242],"REGISTRATION":[243],"ID:":[244],"UMIN000050888.":[245],"URL:":[246],"https://center6.umin.ac.jp/cgi-open-bin/ctr_e/ctr_view.cgi?recptno=R000057998.":[247]},"counts_by_year":[],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2026-11-07T00:00:00"}