{"id":"https://openalex.org/W7225412101","doi":"https://doi.org/10.46989/001c.172499","title":"Dose-dependent biphasic effects of Eucommia ulmoides extract on growth performance and gut-microbiota-liver axis in largemouth bass ( Micropterus salmoides )","display_name":"Dose-dependent biphasic effects of Eucommia ulmoides extract on growth performance and gut-microbiota-liver axis in largemouth bass ( Micropterus salmoides )","publication_year":2026,"publication_date":"2026-11-06","ids":{"openalex":"https://openalex.org/W7225412101","doi":"https://doi.org/10.46989/001c.172499"},"language":"en","primary_location":{"id":"doi:10.46989/001c.172499","doi":"https://doi.org/10.46989/001c.172499","is_oa":true,"landing_page_url":"https://doi.org/10.46989/001c.172499","pdf_url":"https://ija.scholasticahq.com/article/172499.pdf","source":{"id":"https://openalex.org/S5407048835","display_name":"Israeli Journal of Aquaculture - Bamidgeh","issn_l":"3067-0152","issn":["3067-0152"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Israeli Journal of Aquaculture - Bamidgeh","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://ija.scholasticahq.com/article/172499.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5161026334","display_name":"Yuan Tian","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I38756568","display_name":"Xinyang Agriculture and Forestry University","ror":"https://ror.org/017t6fa07","country_code":"CN","type":"education","lineage":["https://openalex.org/I38756568"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuan Tian","raw_affiliation_strings":["Dingyuanchun Modern Agriculture Technology Co., Ltd. of Gushi County, Xinyang 464000, China","Fishery Biological Engineering Technology Research Center of Henan Province, Xinyang 464000, China","School of Fisheries, Xinyang Agriculture and Forestry University, Xinyang 464000, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dingyuanchun Modern Agriculture Technology Co., Ltd. of Gushi County, Xinyang 464000, China","institution_ids":[]},{"raw_affiliation_string":"Fishery Biological Engineering Technology Research Center of Henan Province, Xinyang 464000, China","institution_ids":[]},{"raw_affiliation_string":"School of Fisheries, Xinyang Agriculture and Forestry University, Xinyang 464000, China","institution_ids":["https://openalex.org/I38756568"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053159195","display_name":"Shufang Gao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I38756568","display_name":"Xinyang Agriculture and Forestry University","ror":"https://ror.org/017t6fa07","country_code":"CN","type":"education","lineage":["https://openalex.org/I38756568"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shufang Gao","raw_affiliation_strings":["Fishery Biological Engineering Technology Research Center of Henan Province, Xinyang 464000, China","School of Fisheries, Xinyang Agriculture and Forestry University, Xinyang 464000, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fishery Biological Engineering Technology Research Center of Henan Province, Xinyang 464000, China","institution_ids":[]},{"raw_affiliation_string":"School of Fisheries, Xinyang Agriculture and Forestry University, Xinyang 464000, China","institution_ids":["https://openalex.org/I38756568"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161064905","display_name":"Yang Zhou","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yang Zhou","raw_affiliation_strings":["Xinyang Nanwan Reservoir Fishery Development Co., Ltd., Xinyang 464000, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Xinyang Nanwan Reservoir Fishery Development Co., Ltd., Xinyang 464000, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160999623","display_name":"Yongmou Chen","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yongmou Chen","raw_affiliation_strings":["Changsheng Agricultural Professional Cooperative of Guangshan County, Xinyang 464000, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Changsheng Agricultural Professional Cooperative of Guangshan County, Xinyang 464000, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100339362","display_name":"Hong Li","orcid":"https://orcid.org/0000-0001-9984-3849","observed_orcids":["https://orcid.org/0000-0001-9984-3849"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Honghua Li","raw_affiliation_strings":["Luoshan County Yuyang Agricultural Development Co., Ltd., Xinyang 464000, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Luoshan County Yuyang Agricultural Development Co., Ltd., Xinyang 464000, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161020593","display_name":"Guilin Chi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Guilin Chi","raw_affiliation_strings":["Dingyuanchun Modern Agriculture Technology Co., Ltd. of Gushi County, Xinyang 464000, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dingyuanchun Modern Agriculture Technology Co., Ltd. of Gushi County, Xinyang 464000, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161127306","display_name":"Yongxu Cheng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I109935558","display_name":"Ningbo University","ror":"https://ror.org/03et85d35","country_code":"CN","type":"education","lineage":["https://openalex.org/I109935558"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yongxu Cheng","raw_affiliation_strings":["School of Marine Sciences, Ningbo University, Ningbo 315832, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Marine Sciences, Ningbo University, Ningbo 315832, China","institution_ids":["https://openalex.org/I109935558"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161039855","display_name":"Xusheng Guo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I38756568","display_name":"Xinyang Agriculture and Forestry University","ror":"https://ror.org/017t6fa07","country_code":"CN","type":"education","lineage":["https://openalex.org/I38756568"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xusheng Guo","raw_affiliation_strings":["Fishery Biological Engineering Technology Research Center of Henan Province, Xinyang 464000, China","School of Fisheries, Xinyang Agriculture and Forestry University, Xinyang 464000, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fishery Biological Engineering Technology Research Center of Henan Province, Xinyang 464000, China","institution_ids":[]},{"raw_affiliation_string":"School of Fisheries, Xinyang Agriculture and Forestry University, Xinyang 464000, China","institution_ids":["https://openalex.org/I38756568"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5123414229","display_name":"Jin Meng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I38756568","display_name":"Xinyang Agriculture and Forestry University","ror":"https://ror.org/017t6fa07","country_code":"CN","type":"education","lineage":["https://openalex.org/I38756568"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jin Meng","raw_affiliation_strings":["Fishery Biological Engineering Technology Research Center of Henan Province, Xinyang 464000, China","Luoshan County Yuyang Agricultural Development Co., Ltd., Xinyang 464000, China","School of Fisheries, Xinyang Agriculture and Forestry University, Xinyang 464000, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Fishery Biological Engineering Technology Research Center of Henan Province, Xinyang 464000, China","institution_ids":[]},{"raw_affiliation_string":"Luoshan County Yuyang Agricultural Development Co., Ltd., Xinyang 464000, China","institution_ids":[]},{"raw_affiliation_string":"School of Fisheries, Xinyang Agriculture and Forestry University, Xinyang 464000, China","institution_ids":["https://openalex.org/I38756568"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103820856","display_name":"Yongtao Tang","orcid":"https://orcid.org/0000-0001-9847-4527","observed_orcids":["https://orcid.org/0000-0001-9847-4527"]},"institutions":[{"id":"https://openalex.org/I38756568","display_name":"Xinyang Agriculture and Forestry University","ror":"https://ror.org/017t6fa07","country_code":"CN","type":"education","lineage":["https://openalex.org/I38756568"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yongtao Tang","raw_affiliation_strings":["Changsheng Agricultural Professional Cooperative of Guangshan County, Xinyang 464000, China","Fishery Biological Engineering Technology Research Center of Henan Province, Xinyang 464000, China","School of Fisheries, Xinyang Agriculture and Forestry University, Xinyang 464000, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Changsheng Agricultural Professional Cooperative of Guangshan County, Xinyang 464000, China","institution_ids":[]},{"raw_affiliation_string":"Fishery Biological Engineering Technology Research Center of Henan Province, Xinyang 464000, China","institution_ids":[]},{"raw_affiliation_string":"School of Fisheries, Xinyang Agriculture and Forestry University, Xinyang 464000, China","institution_ids":["https://openalex.org/I38756568"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"78","issue":"4","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10450","display_name":"Aquaculture Nutrition and Growth","score":0.8544999957084656,"subfield":{"id":"https://openalex.org/subfields/1104","display_name":"Aquatic Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10450","display_name":"Aquaculture Nutrition and Growth","score":0.8544999957084656,"subfield":{"id":"https://openalex.org/subfields/1104","display_name":"Aquatic Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10506","display_name":"Aquaculture disease management and microbiota","score":0.14339999854564667,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10152","display_name":"Animal Nutrition and Physiology","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/largemouth-bass","display_name":"largemouth bass","score":0.9980000257492065},{"id":"https://openalex.org/keywords/herbal-feed-additives","display_name":"herbal feed additives","score":0.8769999742507935},{"id":"https://openalex.org/keywords/antibiotic-alternatives","display_name":"antibiotic alternatives","score":0.7609999775886536},{"id":"https://openalex.org/keywords/dose-response-relationship","display_name":"dose-response relationship","score":0.6349999904632568},{"id":"https://openalex.org/keywords/hormesis","display_name":"hormesis","score":0.8320000171661377},{"id":"https://openalex.org/keywords/growth-performance","display_name":"growth performance","score":0.8349999785423279},{"id":"https://openalex.org/keywords/intestinal-morphology","display_name":"intestinal morphology","score":0.7279999852180481},{"id":"https://openalex.org/keywords/hepatic-antioxidant-capacity","display_name":"hepatic antioxidant capacity","score":0.6909999847412109},{"id":"https://openalex.org/keywords/blood-chemistry","display_name":"serum biochemistry","score":0.9430000185966492},{"id":"https://openalex.org/keywords/clostridium-sensu-stricto","display_name":"Clostridium sensu stricto","score":0.8379999995231628},{"id":"https://openalex.org/keywords/microbial-diversity","display_name":"microbial diversity","score":0.6930000185966492},{"id":"https://openalex.org/keywords/fish-feed-supplementation","display_name":"fish feed supplementation","score":0.49399998784065247},{"id":"https://openalex.org/keywords/aquafeed","display_name":"aquaculture feed","score":0.5910000205039978}],"concepts":[{"id":"https://openalex.org/C2780716849","wikidata":"https://www.wikidata.org/wiki/Q654061","display_name":"Micropterus","level":3,"score":0.5882999897003174},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.5602999925613403},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.49559998512268066},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.47279998660087585},{"id":"https://openalex.org/C2779399885","wikidata":"https://www.wikidata.org/wiki/Q413288","display_name":"Bile acid","level":2,"score":0.47099998593330383},{"id":"https://openalex.org/C2777182073","wikidata":"https://www.wikidata.org/wiki/Q1224135","display_name":"Bass (fish)","level":2,"score":0.46549999713897705},{"id":"https://openalex.org/C2779843069","wikidata":"https://www.wikidata.org/wiki/Q193213","display_name":"Butyric acid","level":2,"score":0.45489999651908875},{"id":"https://openalex.org/C2780409773","wikidata":"https://www.wikidata.org/wiki/Q131528","display_name":"Eucommia ulmoides","level":4,"score":0.44999998807907104},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.44110000133514404},{"id":"https://openalex.org/C140793950","wikidata":"https://www.wikidata.org/wiki/Q168091","display_name":"Animal science","level":1,"score":0.39089998602867126},{"id":"https://openalex.org/C543025807","wikidata":"https://www.wikidata.org/wiki/Q61476","display_name":"Fatty acid","level":2,"score":0.36570000648498535},{"id":"https://openalex.org/C2781092032","wikidata":"https://www.wikidata.org/wiki/Q327663","display_name":"Clostridium","level":3,"score":0.3343999981880188},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.32850000262260437},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.3212999999523163},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.31200000643730164},{"id":"https://openalex.org/C2780710107","wikidata":"https://www.wikidata.org/wiki/Q384912","display_name":"Hepatopancreas","level":2,"score":0.30970001220703125},{"id":"https://openalex.org/C2775941134","wikidata":"https://www.wikidata.org/wiki/Q813622","display_name":"Goblet cell","level":3,"score":0.30799999833106995},{"id":"https://openalex.org/C8243546","wikidata":"https://www.wikidata.org/wiki/Q419074","display_name":"Very low-density lipoprotein","level":4,"score":0.30160000920295715},{"id":"https://openalex.org/C71572567","wikidata":"https://www.wikidata.org/wiki/Q864231","display_name":"Bioaccumulation","level":2,"score":0.29440000653266907},{"id":"https://openalex.org/C86909935","wikidata":"https://www.wikidata.org/wiki/Q188989","display_name":"Aquaculture","level":3,"score":0.2883000075817108},{"id":"https://openalex.org/C2778918659","wikidata":"https://www.wikidata.org/wiki/Q186915","display_name":"Phospholipid","level":3,"score":0.2838999927043915},{"id":"https://openalex.org/C5426402","wikidata":"https://www.wikidata.org/wiki/Q2462753","display_name":"Brush border","level":4,"score":0.275299996137619},{"id":"https://openalex.org/C2991897288","wikidata":"https://www.wikidata.org/wiki/Q970537","display_name":"Saturated fatty acid","level":3,"score":0.27390000224113464},{"id":"https://openalex.org/C22830521","wikidata":"https://www.wikidata.org/wiki/Q649967","display_name":"Feed conversion ratio","level":3,"score":0.2671000063419342},{"id":"https://openalex.org/C115961737","wikidata":"https://www.wikidata.org/wiki/Q1516282","display_name":"Juvenile","level":2,"score":0.26460000872612},{"id":"https://openalex.org/C158278297","wikidata":"https://www.wikidata.org/wiki/Q1756633","display_name":"Aquatic animal","level":3,"score":0.26420000195503235},{"id":"https://openalex.org/C170835558","wikidata":"https://www.wikidata.org/wiki/Q17153","display_name":"Amylase","level":3,"score":0.26269999146461487},{"id":"https://openalex.org/C539455810","wikidata":"https://www.wikidata.org/wiki/Q739734","display_name":"Gut flora","level":2,"score":0.25839999318122864},{"id":"https://openalex.org/C27881333","wikidata":"https://www.wikidata.org/wiki/Q864895","display_name":"Biotransformation","level":3,"score":0.2574999928474426},{"id":"https://openalex.org/C2991684624","wikidata":"https://www.wikidata.org/wiki/Q193583","display_name":"Abdominal fat","level":3,"score":0.2547000050544739},{"id":"https://openalex.org/C2779946292","wikidata":"https://www.wikidata.org/wiki/Q1786125","display_name":"Fish oil","level":3,"score":0.25440001487731934}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.46989/001c.172499","doi":"https://doi.org/10.46989/001c.172499","is_oa":true,"landing_page_url":"https://doi.org/10.46989/001c.172499","pdf_url":"https://ija.scholasticahq.com/article/172499.pdf","source":{"id":"https://openalex.org/S5407048835","display_name":"Israeli Journal of Aquaculture - Bamidgeh","issn_l":"3067-0152","issn":["3067-0152"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Israeli Journal of Aquaculture - Bamidgeh","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.46989/001c.172499","doi":"https://doi.org/10.46989/001c.172499","is_oa":true,"landing_page_url":"https://doi.org/10.46989/001c.172499","pdf_url":"https://ija.scholasticahq.com/article/172499.pdf","source":{"id":"https://openalex.org/S5407048835","display_name":"Israeli Journal of Aquaculture - Bamidgeh","issn_l":"3067-0152","issn":["3067-0152"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Israeli Journal of Aquaculture - Bamidgeh","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.4000000059604645,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7225412101.pdf","grobid_xml":"https://content.openalex.org/works/W7225412101.grobid-xml"},"referenced_works_count":39,"referenced_works":["https://openalex.org/W1871987727","https://openalex.org/W1964729092","https://openalex.org/W1976950210","https://openalex.org/W2010525365","https://openalex.org/W2013155237","https://openalex.org/W2027612310","https://openalex.org/W2033898136","https://openalex.org/W2198819611","https://openalex.org/W2546861868","https://openalex.org/W2582655426","https://openalex.org/W2891573404","https://openalex.org/W2920964512","https://openalex.org/W2940060404","https://openalex.org/W2946331888","https://openalex.org/W2948828293","https://openalex.org/W2982644611","https://openalex.org/W2992738957","https://openalex.org/W3022673979","https://openalex.org/W3047193490","https://openalex.org/W3072246308","https://openalex.org/W3095735333","https://openalex.org/W3107103643","https://openalex.org/W3113946399","https://openalex.org/W3135837552","https://openalex.org/W3213397262","https://openalex.org/W4206035504","https://openalex.org/W4295813915","https://openalex.org/W4304811973","https://openalex.org/W4319034744","https://openalex.org/W4323051066","https://openalex.org/W4366816283","https://openalex.org/W4378710467","https://openalex.org/W4380681064","https://openalex.org/W4391461026","https://openalex.org/W4406590905","https://openalex.org/W4409108340","https://openalex.org/W4412578663","https://openalex.org/W4415421360","https://openalex.org/W7122495662"],"related_works":["https://openalex.org/W4413385182","https://openalex.org/W7201873920","https://openalex.org/W4410990307","https://openalex.org/W4406236264","https://openalex.org/W4221122877","https://openalex.org/W4416851267","https://openalex.org/W7171502009","https://openalex.org/W4394629932","https://openalex.org/W7204141120","https://openalex.org/W4401907876"],"abstract_inverted_index":{"The":[0,81],"intensification":[1],"of":[2,158],"largemouth":[3,42],"bass":[4,43],"aquaculture":[5,275],"necessitates":[6],"safe,":[7],"efficacious":[8],"feed":[9],"additives":[10],"to":[11,46],"replace":[12],"antibiotics.":[13],"Eucommia":[14],"ulmoides":[15],"extract":[16],"(EUE)":[17],"exhibits":[18],"phytogenic":[19],"potential,":[20],"yet":[21,260],"its":[22],"dose-response":[23],"efficacy":[24],"and":[25,75,97,132,162,173,192,226,237,255],"gut-microbiota-mediated":[26],"mechanisms":[27],"remain":[28],"unresolved":[29],"in":[30,183,223,233,273],"this":[31,261],"species.":[32],"A":[33],"120-day":[34],"feeding":[35],"trial":[36],"was":[37],"conducted":[38],"with":[39,57,103,120,187],"990":[40],"juvenile":[41],"randomly":[44],"allocated":[45],"six":[47],"dietary":[48],"treatments:":[49],"basal":[50,54],"diet":[51,55],"(control)":[52],"or":[53,64],"supplemented":[56],"EUE":[58,87,112,209],"at":[59,152,258],"0.3\u2030,":[60,259],"0.6\u2030,":[61],"0.9\u2030,":[62,153],"1.2\u2030,":[63],"1.5\u2030.":[65],"Growth":[66],"performance,":[67],"hepatic":[68,117],"antioxidant":[69],"capacity,":[70],"serum":[71],"biochemistry,":[72],"intestinal":[73,133],"morphology,":[74],"gut":[76],"microbiota":[77],"were":[78],"systematically":[79],"evaluated.":[80],"results":[82],"showed":[83],"that":[84,207],"the":[85,104,114,184,193,224,247,251,269],"0.9\u2030":[86,111,185,208],"group":[88],"achieved":[89],"optimal":[90],"outcomes:":[91],"weight":[92],"gain":[93],"increased":[94],"by":[95,100,155],"15.7%":[96],"FCR":[98],"decreased":[99],"14.3%":[101],"compared":[102],"control":[105,225],"(":[106,164,200],"P":[107,165,201],"<":[108,166,202],"0.05).":[109,203],"Histologically,":[110],"preserved":[113],"most":[115],"compact":[116],"lobular":[118],"architecture":[119,182],"minimal":[121],"lipid":[122],"vacuolization,":[123],"whereas":[124],"concentrations":[125,157],"\u2265":[126],"1.2\u2030":[127],"induced":[128],"dose-dependent":[129],"hepatocyte":[130],"vacuolation":[131],"goblet":[134],"cell":[135],"hyperplasia,":[136],"revealing":[137],"a":[138,146,179,229,243],"biphasic,":[139],"hormesis-like":[140],"dose-response.":[141],"Serum":[142],"biochemical":[143],"profiling":[144],"identified":[145],"distinctive":[147],"\u201chigh-flux,":[148],"high-clearance\u201d":[149],"metabolic":[150],"phenotype":[151],"characterized":[154],"peak":[156],"HDL,":[159],"total":[160],"protein,":[161],"cholesterol":[163,171],"0.05),":[167],"indicating":[168],"enhanced":[169],"reverse":[170],"transport":[172],"protein":[174],"anabolism.":[175],"Intestinal":[176],"morphometry":[177],"demonstrated":[178],"\u201ctall-and-dense\u201d":[180],"absorptive":[181],"group,":[186],"significantly":[188],"elevated":[189],"villus":[190,195],"height":[191],"highest":[194,252],"density":[196],"among":[197],"all":[198],"treatments":[199],"Microbiota":[204],"analysis":[205],"revealed":[206],"selectively":[210],"enriched":[211],"Clostridium":[212],"\u2060":[213,214,216,217],"sensu":[215],"stricto":[218],"_1":[219],"(13.61%":[220],"vs.":[221],"<0.1%":[222],"high-dose":[227],"groups),":[228],"keystone":[230],"genus":[231],"implicated":[232],"bile":[234],"acid":[235,240],"biotransformation":[236],"short-chain":[238],"fatty":[239],"metabolism,":[241],"suggesting":[242],"gut-microbiota-liver":[244],"axis":[245],"as":[246],"mechanistic":[248],"driver.":[249],"Paradoxically,":[250],"microbial":[253],"diversity":[254],"richness":[256],"occurred":[257],"did":[262],"not":[263],"translate":[264],"into":[265],"improved":[266],"growth,":[267],"challenging":[268],"prevailing":[270],"\u201cdiversity-equals-health\u201d":[271],"paradigm":[272],"intensive":[274],"systems.":[276]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2026-11-07T00:00:00"}