{"id":"https://openalex.org/W7225410573","doi":"https://doi.org/10.1128/jvi.01155-26","title":"Clinically relevant RSV anti-F antibodies exhibit comparable inhibition of syncytium formation despite marked differences in neutralization potency","display_name":"Clinically relevant RSV anti-F antibodies exhibit comparable inhibition of syncytium formation despite marked differences in neutralization potency","publication_year":2026,"publication_date":"2026-11-06","ids":{"openalex":"https://openalex.org/W7225410573","doi":"https://doi.org/10.1128/jvi.01155-26","pmid":"https://pubmed.ncbi.nlm.nih.gov/42992841"},"language":"en","primary_location":{"id":"doi:10.1128/jvi.01155-26","doi":"https://doi.org/10.1128/jvi.01155-26","is_oa":true,"landing_page_url":"https://doi.org/10.1128/jvi.01155-26","pdf_url":null,"source":{"id":"https://openalex.org/S96615428","display_name":"Journal of Virology","issn_l":"0022-538X","issn":["0022-538X","1070-6321","1098-5514"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Virology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.1128/jvi.01155-26","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5114325727","display_name":"Lotte T. Azink","orcid":"https://orcid.org/0000-0002-0960-2097","observed_orcids":["https://orcid.org/0000-0002-0960-2097"]},"institutions":[{"id":"https://openalex.org/I3018483916","display_name":"University Medical Center Utrecht","ror":"https://ror.org/0575yy874","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I3018483916"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Lotte T. Azink","raw_affiliation_strings":["Department of Medical Microbiology, University Medical Center Utrecht"],"raw_orcid":"https://orcid.org/0000-0002-0960-2097","affiliations":[{"raw_affiliation_string":"Department of Medical Microbiology, University Medical Center Utrecht","institution_ids":["https://openalex.org/I3018483916"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161064807","display_name":"Thomas Boonstoppel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3018483916","display_name":"University Medical Center Utrecht","ror":"https://ror.org/0575yy874","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I3018483916"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Thomas Boonstoppel","raw_affiliation_strings":["Department of Medical Microbiology, University Medical Center Utrecht"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Microbiology, University Medical Center Utrecht","institution_ids":["https://openalex.org/I3018483916"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161103432","display_name":"Daniel Ram\u00edrez Alfaro","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3018483916","display_name":"University Medical Center Utrecht","ror":"https://ror.org/0575yy874","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I3018483916"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Daniel Ram\u00edrez Alfaro","raw_affiliation_strings":["Department of Medical Microbiology, University Medical Center Utrecht"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Microbiology, University Medical Center Utrecht","institution_ids":["https://openalex.org/I3018483916"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5161013836","display_name":"Claudia van Hal","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I3018483916","display_name":"University Medical Center Utrecht","ror":"https://ror.org/0575yy874","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I3018483916"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Claudia van Hal","raw_affiliation_strings":["Department of Medical Microbiology, University Medical Center Utrecht"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Microbiology, University Medical Center Utrecht","institution_ids":["https://openalex.org/I3018483916"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042316785","display_name":"Emmanuel J. H. J. Wiertz","orcid":"https://orcid.org/0000-0001-6080-7058","observed_orcids":["https://orcid.org/0000-0001-6080-7058"]},"institutions":[{"id":"https://openalex.org/I3018483916","display_name":"University Medical Center Utrecht","ror":"https://ror.org/0575yy874","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I3018483916"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Emmanuel J. H. J. Wiertz","raw_affiliation_strings":["Department of Medical Microbiology, University Medical Center Utrecht"],"raw_orcid":"https://orcid.org/0000-0001-6080-7058","affiliations":[{"raw_affiliation_string":"Department of Medical Microbiology, University Medical Center Utrecht","institution_ids":["https://openalex.org/I3018483916"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5074465773","display_name":"Robert Jan Lebbink","orcid":"https://orcid.org/0000-0002-1981-0420","observed_orcids":["https://orcid.org/0000-0002-1981-0420"]},"institutions":[{"id":"https://openalex.org/I3018483916","display_name":"University Medical Center Utrecht","ror":"https://ror.org/0575yy874","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I3018483916"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Robert Jan Lebbink","raw_affiliation_strings":["Department of Medical Microbiology, University Medical Center Utrecht"],"raw_orcid":"https://orcid.org/0000-0002-1981-0420","affiliations":[{"raw_affiliation_string":"Department of Medical Microbiology, University Medical Center Utrecht","institution_ids":["https://openalex.org/I3018483916"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I3018483916"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"e0115526","last_page":"e0115526"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11243","display_name":"Respiratory viral infections research","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11243","display_name":"Respiratory viral infections research","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11135","display_name":"Virology and Viral Diseases","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/respiratory-syncytial-virus","display_name":"respiratory syncytial virus","score":0.9980000257492065},{"id":"https://openalex.org/keywords/syncytium-formation","display_name":"syncytium formation","score":0.9049999713897705},{"id":"https://openalex.org/keywords/rsv-fusion-protein","display_name":"RSV fusion protein","score":0.7229999899864197},{"id":"https://openalex.org/keywords/cell-to-cell-fusion","display_name":"cell-to-cell fusion","score":0.8420000076293945},{"id":"https://openalex.org/keywords/virus-neutralization","display_name":"virus neutralization","score":0.5889999866485596},{"id":"https://openalex.org/keywords/palivizumab","display_name":"palivizumab","score":0.9010000228881836},{"id":"https://openalex.org/keywords/nirsevimab","display_name":"nirsevimab","score":1.0},{"id":"https://openalex.org/keywords/clesrovimab","display_name":"clesrovimab","score":0.9950000047683716},{"id":"https://openalex.org/keywords/antibody-potency","display_name":"antibody potency","score":0.37400001287460327},{"id":"https://openalex.org/keywords/viral-pathogenesis","display_name":"viral pathogenesis","score":0.5080000162124634},{"id":"https://openalex.org/keywords/cell-to-cell-spread","display_name":"cell-to-cell transmission","score":0.6370000243186951},{"id":"https://openalex.org/keywords/hep-2-cells","display_name":"HEp-2 cells","score":0.7049999833106995},{"id":"https://openalex.org/keywords/a549-cells","display_name":"A549 cells","score":0.9990000128746033}],"concepts":[{"id":"https://openalex.org/C40479148","wikidata":"https://www.wikidata.org/wiki/Q844460","display_name":"Syncytium","level":3,"score":0.982200026512146},{"id":"https://openalex.org/C14086860","wikidata":"https://www.wikidata.org/wiki/Q337120","display_name":"Neutralization","level":3,"score":0.8719000220298767},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7892000079154968},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.6697999835014343},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.6685000061988831},{"id":"https://openalex.org/C542903549","wikidata":"https://www.wikidata.org/wiki/Q422248","display_name":"Monoclonal antibody","level":3,"score":0.6665999889373779},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.6647999882698059},{"id":"https://openalex.org/C92488253","wikidata":"https://www.wikidata.org/wiki/Q56592403","display_name":"Cell fusion","level":3,"score":0.5914000272750854},{"id":"https://openalex.org/C58475186","wikidata":"https://www.wikidata.org/wiki/Q4118894","display_name":"Viral entry","level":4,"score":0.5440999865531921},{"id":"https://openalex.org/C2780355102","wikidata":"https://www.wikidata.org/wiki/Q1753162","display_name":"Mononegavirales","level":5,"score":0.4392000138759613},{"id":"https://openalex.org/C2779261636","wikidata":"https://www.wikidata.org/wiki/Q7003054","display_name":"Neutralizing antibody","level":3,"score":0.430400013923645},{"id":"https://openalex.org/C2780813555","wikidata":"https://www.wikidata.org/wiki/Q911129","display_name":"Paramyxoviridae","level":4,"score":0.41040000319480896},{"id":"https://openalex.org/C103038307","wikidata":"https://www.wikidata.org/wiki/Q6556360","display_name":"Lipid bilayer fusion","level":3,"score":0.3853999972343445},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.38339999318122864},{"id":"https://openalex.org/C57992300","wikidata":"https://www.wikidata.org/wiki/Q2066956","display_name":"Potency","level":3,"score":0.37310001254081726},{"id":"https://openalex.org/C28406088","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Extracellular","level":2,"score":0.31859999895095825},{"id":"https://openalex.org/C534529494","wikidata":"https://www.wikidata.org/wiki/Q7891","display_name":"Respiratory system","level":2,"score":0.31189998984336853},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.3050000071525574},{"id":"https://openalex.org/C89138240","wikidata":"https://www.wikidata.org/wiki/Q3066564","display_name":"Vero cell","level":3,"score":0.30250000953674316},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.26820001006126404},{"id":"https://openalex.org/C2777648638","wikidata":"https://www.wikidata.org/wiki/Q57751738","display_name":"Coronavirus","level":5,"score":0.26649999618530273},{"id":"https://openalex.org/C163864487","wikidata":"https://www.wikidata.org/wiki/Q6901461","display_name":"Monoclonal","level":4,"score":0.25119999051094055}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1128/jvi.01155-26","doi":"https://doi.org/10.1128/jvi.01155-26","is_oa":true,"landing_page_url":"https://doi.org/10.1128/jvi.01155-26","pdf_url":null,"source":{"id":"https://openalex.org/S96615428","display_name":"Journal of Virology","issn_l":"0022-538X","issn":["0022-538X","1070-6321","1098-5514"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Virology","raw_type":"journal-article"},{"id":"pmid:42992841","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42992841","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of virology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1128/jvi.01155-26","doi":"https://doi.org/10.1128/jvi.01155-26","is_oa":true,"landing_page_url":"https://doi.org/10.1128/jvi.01155-26","pdf_url":null,"source":{"id":"https://openalex.org/S96615428","display_name":"Journal of Virology","issn_l":"0022-538X","issn":["0022-538X","1070-6321","1098-5514"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Virology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.979200005531311,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":75,"referenced_works":["https://openalex.org/W156352715","https://openalex.org/W935156426","https://openalex.org/W1490759475","https://openalex.org/W1597676159","https://openalex.org/W1886359527","https://openalex.org/W1967087334","https://openalex.org/W1970842087","https://openalex.org/W1977544423","https://openalex.org/W1988459634","https://openalex.org/W1991730258","https://openalex.org/W1999032534","https://openalex.org/W2004293344","https://openalex.org/W2043056303","https://openalex.org/W2055901026","https://openalex.org/W2071513218","https://openalex.org/W2073045612","https://openalex.org/W2075446313","https://openalex.org/W2083264351","https://openalex.org/W2087730240","https://openalex.org/W2102146833","https://openalex.org/W2109958803","https://openalex.org/W2117608592","https://openalex.org/W2131493422","https://openalex.org/W2131955135","https://openalex.org/W2139907403","https://openalex.org/W2140228548","https://openalex.org/W2142544822","https://openalex.org/W2152604492","https://openalex.org/W2164480843","https://openalex.org/W2167279371","https://openalex.org/W2168298679","https://openalex.org/W2270869679","https://openalex.org/W2344643027","https://openalex.org/W2611361909","https://openalex.org/W2617417082","https://openalex.org/W2765110787","https://openalex.org/W2790815850","https://openalex.org/W2888589836","https://openalex.org/W2911720173","https://openalex.org/W2947446118","https://openalex.org/W2951114697","https://openalex.org/W2972594574","https://openalex.org/W2984679135","https://openalex.org/W3112083445","https://openalex.org/W3157749513","https://openalex.org/W3181258927","https://openalex.org/W3198233589","https://openalex.org/W4205246021","https://openalex.org/W4206142017","https://openalex.org/W4220780642","https://openalex.org/W4281385327","https://openalex.org/W4292315834","https://openalex.org/W4308486212","https://openalex.org/W4309836253","https://openalex.org/W4366351379","https://openalex.org/W4384069186","https://openalex.org/W4388934269","https://openalex.org/W4390607257","https://openalex.org/W4395050400","https://openalex.org/W4404593642","https://openalex.org/W4405185563","https://openalex.org/W4405267351","https://openalex.org/W4409411651","https://openalex.org/W4410469282","https://openalex.org/W4410791952","https://openalex.org/W4412091857","https://openalex.org/W4415701415","https://openalex.org/W4415756845","https://openalex.org/W4415898203","https://openalex.org/W4416385684","https://openalex.org/W7119491135","https://openalex.org/W7124418380","https://openalex.org/W7129028142","https://openalex.org/W7133488208","https://openalex.org/W7135411520"],"related_works":["https://openalex.org/W2139907403","https://openalex.org/W2075446313","https://openalex.org/W3093472344","https://openalex.org/W2995377219","https://openalex.org/W1988459634","https://openalex.org/W2159725619","https://openalex.org/W2899088252","https://openalex.org/W4389950345","https://openalex.org/W2142544822","https://openalex.org/W2141501895"],"abstract_inverted_index":{"Respiratory":[0],"syncytial":[1,244],"virus":[2,96,153,186,245],"(RSV)":[3,246],"is":[4,25,41,209,247,266,369],"a":[5,123,169,201,220,248,336,361],"major":[6],"cause":[7,250],"of":[8,22,28,196,205,231,251,263,365,380],"lower":[9],"respiratory":[10,252],"tract":[11],"infections":[12],"in":[13,148,156,168,176,254],"infants,":[14,255],"immunocompromised":[15,259],"individuals,":[16],"and":[17,35,79,90,144,151,158,163,181,227,240,258,275,289,346,389],"older":[18,256],"adults.":[19],"A":[20,261],"hallmark":[21,262],"RSV":[23,45,88,239,264,305,388],"infection":[24,265],"the":[26,44,229,378],"formation":[27,66,105,132,167,291,322,345],"multinucleated":[29],"syncytia":[30],"through":[31],"fusion":[32,46,199,306],"between":[33],"infected":[34,52],"adjacent":[36],"uninfected":[37],"cells.":[38,81,160],"This":[39],"process":[40],"mediated":[42],"by":[43,213,349,373],"protein":[47],"(RSV":[48],"F)":[49],"expressed":[50],"on":[51,58],"cells,":[53],"which":[54],"interacts":[55],"with":[56,172,286],"receptors":[57],"neighboring":[59],"cells":[60],"to":[61,75,102,128,223,272,300,319,341],"drive":[62],"membrane":[63],"fusion.":[64,119],"Syncytium":[65],"may":[67,292],"facilitate":[68],"cell-to-cell":[69,118,198,294],"spread":[70,274,295],"while":[71,296],"reducing":[72],"virion":[73,298],"exposure":[74,299],"extracellular":[76,301],"neutralizing":[77,302],"antibodies":[78,85,207,237,309,367,386],"immune":[80],"Clinically":[82],"used":[83,313],"monoclonal":[84,308],"(mAbs)":[86,310],"target":[87],"F":[89],"are":[91,311],"routinely":[92],"evaluated":[93,139],"using":[94],"conventional":[95,152,214,326,374],"neutralization":[97,154,187,215,327,375],"assays.":[98,216],"However,":[99],"their":[100,146,317],"ability":[101,318],"inhibit":[103,320],"syncytium":[104,131,149,166,225,267,290,321,344,358],"remains":[106,278,323],"poorly":[107],"characterized":[108],"because":[109],"these":[110],"assays":[111,155,328],"primarily":[112,329],"measure":[113,129,330,342],"virus-to-cell":[114,331],"entry":[115],"rather":[116],"than":[117,189],"Here,":[120,333],"we":[121,138,334],"present":[122],"quantitative":[124,221,337],"flow":[125,338],"cytometry-based":[126,339],"assay":[127,218,340],"RSV-induced":[130,197,343],"during":[133],"infection.":[134],"Using":[135],"this":[136],"assay,":[137],"clinically":[140,350],"relevant":[141,351],"anti-F":[142,206,352,366],"mAbs":[143],"compared":[145],"potency":[147,188],"inhibition":[150,195,226,348,359],"HEp-2":[157],"A549":[159],"Palivizumab,":[161],"nirsevimab,":[162],"clesrovimab":[164,182],"inhibited":[165],"dose-dependent":[170],"manner,":[171],"only":[173],"modest":[174],"differences":[175],"potency.":[177],"In":[178],"contrast,":[179],"nirsevimab":[180],"exhibited":[183],"substantially":[184],"greater":[185],"palivizumab.":[190],"These":[191],"findings":[192],"indicate":[193,356],"that":[194,208,357,368],"represents":[200,360],"distinct":[202,362],"functional":[203,233,363,382],"property":[204,364],"not":[210,370],"fully":[211,371],"captured":[212,372],"Our":[217,354],"provides":[219],"approach":[222],"assess":[224],"highlights":[228],"value":[230,379],"complementary":[232,381],"readouts":[234,383],"for":[235,314,384],"evaluating":[236,385],"targeting":[238,387],"other":[241,390],"syncytium-forming":[242,391],"viruses.IMPORTANCERespiratory":[243],"leading":[249],"disease":[253,276,287,315],"adults,":[257],"individuals.":[260],"formation,":[268],"although":[269],"its":[270],"contribution":[271],"viral":[273],"pathogenesis":[277],"incompletely":[279],"understood.":[280],"Increased":[281],"fusogenicity":[282],"has":[283],"been":[284],"associated":[285],"severity,":[288],"promote":[293],"limiting":[297],"antibodies.":[303],"Although":[304],"(F)-specific":[307],"increasingly":[312],"prevention,":[316],"unexplored,":[324],"as":[325],"entry.":[332],"describe":[335],"evaluate":[347],"mAbs.":[353],"results":[355],"assays,":[376],"highlighting":[377],"viruses.":[392]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2026-11-07T00:00:00"}
