{"id":"https://openalex.org/W7225337963","doi":"https://doi.org/10.3760/cma.j.cn501113-20250909-00374","title":"\u8840\u6e05\u5b66\u9634\u6027\u7684\u81ea\u8eab\u514d\u75ab\u6027\u809d\u708e\u8bca\u6cbb\u73b0\u72b6\uff1a\u6311\u6218\u4e0e\u8fdb\u5c55","display_name":"\u8840\u6e05\u5b66\u9634\u6027\u7684\u81ea\u8eab\u514d\u75ab\u6027\u809d\u708e\u8bca\u6cbb\u73b0\u72b6\uff1a\u6311\u6218\u4e0e\u8fdb\u5c55","publication_year":2026,"publication_date":"2026-10-20","ids":{"openalex":"https://openalex.org/W7225337963","doi":"https://doi.org/10.3760/cma.j.cn501113-20250909-00374","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13730783"},"language":"zh","primary_location":{"id":"pmh:oai:pubmedcentral.nih.gov:13730783","doi":"https://doi.org/10.3760/cma.j.cn501113-20250909-00374","is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13730783/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13730783/pdf/cjh-34-10-1043.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Zhonghua Gan Zang Bing Za Zhi","raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13730783/pdf/cjh-34-10-1043.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5160859749","display_name":"Ma Luyuan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I111381250","display_name":"Hebei Medical University","ror":"https://ror.org/04eymdx19","country_code":"CN","type":"education","lineage":["https://openalex.org/I111381250"]},{"id":"https://openalex.org/I4210088328","display_name":"Third Hospital of Hebei Medical University","ror":"https://ror.org/004eknx63","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210088328"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ma Luyuan","raw_affiliation_strings":["\u6cb3\u5317\u533b\u79d1\u5927\u5b66\u7b2c\u4e09\u533b\u9662\u611f\u67d3\u79d1\uff0c\u77f3\u5bb6\u5e84 050051, Department of Infectious Diseases, Hebei Medical University Third Hospital, Shijiazhuang 050051, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u6cb3\u5317\u533b\u79d1\u5927\u5b66\u7b2c\u4e09\u533b\u9662\u611f\u67d3\u79d1\uff0c\u77f3\u5bb6\u5e84 050051, Department of Infectious Diseases, Hebei Medical University Third Hospital, Shijiazhuang 050051, China","institution_ids":["https://openalex.org/I111381250","https://openalex.org/I4210088328"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013886414","display_name":"Zhao Qian","orcid":"https://orcid.org/0000-0002-1057-3780","observed_orcids":["https://orcid.org/0000-0002-1057-3780"]},"institutions":[{"id":"https://openalex.org/I111381250","display_name":"Hebei Medical University","ror":"https://ror.org/04eymdx19","country_code":"CN","type":"education","lineage":["https://openalex.org/I111381250"]},{"id":"https://openalex.org/I4210088328","display_name":"Third Hospital of Hebei Medical University","ror":"https://ror.org/004eknx63","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210088328"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhao Qian","raw_affiliation_strings":["\u6cb3\u5317\u533b\u79d1\u5927\u5b66\u7b2c\u4e09\u533b\u9662\u8d28\u91cf\u7ba1\u7406\u4e0e\u63a7\u5236\u5904\uff0c\u77f3\u5bb6\u5e84 050051, Quality-Control-Department, Hebei Medical University Third Hospital, Shijiazhuang 050051, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u6cb3\u5317\u533b\u79d1\u5927\u5b66\u7b2c\u4e09\u533b\u9662\u8d28\u91cf\u7ba1\u7406\u4e0e\u63a7\u5236\u5904\uff0c\u77f3\u5bb6\u5e84 050051, Quality-Control-Department, Hebei Medical University Third Hospital, Shijiazhuang 050051, China","institution_ids":["https://openalex.org/I111381250","https://openalex.org/I4210088328"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160801639","display_name":"Shen Chuan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I111381250","display_name":"Hebei Medical University","ror":"https://ror.org/04eymdx19","country_code":"CN","type":"education","lineage":["https://openalex.org/I111381250"]},{"id":"https://openalex.org/I4210088328","display_name":"Third Hospital of Hebei Medical University","ror":"https://ror.org/004eknx63","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210088328"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shen Chuan","raw_affiliation_strings":["\u6cb3\u5317\u533b\u79d1\u5927\u5b66\u7b2c\u4e09\u533b\u9662\u611f\u67d3\u79d1\uff0c\u77f3\u5bb6\u5e84 050051, Department of Infectious Diseases, Hebei Medical University Third Hospital, Shijiazhuang 050051, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u6cb3\u5317\u533b\u79d1\u5927\u5b66\u7b2c\u4e09\u533b\u9662\u611f\u67d3\u79d1\uff0c\u77f3\u5bb6\u5e84 050051, Department of Infectious Diseases, Hebei Medical University Third Hospital, Shijiazhuang 050051, China","institution_ids":["https://openalex.org/I111381250","https://openalex.org/I4210088328"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5151744312","display_name":"Yuexia Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I111381250","display_name":"Hebei Medical University","ror":"https://ror.org/04eymdx19","country_code":"CN","type":"education","lineage":["https://openalex.org/I111381250"]},{"id":"https://openalex.org/I4210088328","display_name":"Third Hospital of Hebei Medical University","ror":"https://ror.org/004eknx63","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210088328"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Liu Yuexia","raw_affiliation_strings":["\u6cb3\u5317\u533b\u79d1\u5927\u5b66\u7b2c\u4e09\u533b\u9662\u611f\u67d3\u79d1\uff0c\u77f3\u5bb6\u5e84 050051, Department of Infectious Diseases, Hebei Medical University Third Hospital, Shijiazhuang 050051, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u6cb3\u5317\u533b\u79d1\u5927\u5b66\u7b2c\u4e09\u533b\u9662\u611f\u67d3\u79d1\uff0c\u77f3\u5bb6\u5e84 050051, Department of Infectious Diseases, Hebei Medical University Third Hospital, Shijiazhuang 050051, China","institution_ids":["https://openalex.org/I111381250","https://openalex.org/I4210088328"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109374841","display_name":"Liu Fang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I111381250","display_name":"Hebei Medical University","ror":"https://ror.org/04eymdx19","country_code":"CN","type":"education","lineage":["https://openalex.org/I111381250"]},{"id":"https://openalex.org/I4210088328","display_name":"Third Hospital of Hebei Medical University","ror":"https://ror.org/004eknx63","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210088328"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Liu Fang","raw_affiliation_strings":["\u6cb3\u5317\u533b\u79d1\u5927\u5b66\u7b2c\u4e09\u533b\u9662\u611f\u67d3\u79d1\uff0c\u77f3\u5bb6\u5e84 050051, Department of Infectious Diseases, Hebei Medical University Third Hospital, Shijiazhuang 050051, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u6cb3\u5317\u533b\u79d1\u5927\u5b66\u7b2c\u4e09\u533b\u9662\u611f\u67d3\u79d1\uff0c\u77f3\u5bb6\u5e84 050051, Department of Infectious Diseases, Hebei Medical University Third Hospital, Shijiazhuang 050051, China","institution_ids":["https://openalex.org/I111381250","https://openalex.org/I4210088328"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5160970336","display_name":"Zhao Caiyan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I111381250","display_name":"Hebei Medical University","ror":"https://ror.org/04eymdx19","country_code":"CN","type":"education","lineage":["https://openalex.org/I111381250"]},{"id":"https://openalex.org/I4210088328","display_name":"Third Hospital of Hebei Medical University","ror":"https://ror.org/004eknx63","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210088328"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhao Caiyan","raw_affiliation_strings":["\u6cb3\u5317\u533b\u79d1\u5927\u5b66\u7b2c\u4e09\u533b\u9662\u611f\u67d3\u79d1\uff0c\u77f3\u5bb6\u5e84 050051, Department of Infectious Diseases, Hebei Medical University Third Hospital, Shijiazhuang 050051, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u6cb3\u5317\u533b\u79d1\u5927\u5b66\u7b2c\u4e09\u533b\u9662\u611f\u67d3\u79d1\uff0c\u77f3\u5bb6\u5e84 050051, Department of Infectious Diseases, Hebei Medical University Third Hospital, Shijiazhuang 050051, China","institution_ids":["https://openalex.org/I111381250","https://openalex.org/I4210088328"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11834","display_name":"Liver Diseases and Immunity","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11834","display_name":"Liver Diseases and Immunity","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11576","display_name":"IgG4-Related and Inflammatory Diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12460","display_name":"Pediatric Hepatobiliary Diseases and Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/seronegative-autoimmune-hepatitis","display_name":"seronegative autoimmune hepatitis","score":0.9990000128746033},{"id":"https://openalex.org/keywords/autoimmune-hepatitis","display_name":"autoimmune hepatitis","score":0.8130000233650208},{"id":"https://openalex.org/keywords/diagnostic-criteria","display_name":"diagnostic criteria","score":0.906000018119812},{"id":"https://openalex.org/keywords/biomarkers","display_name":"biomarkers","score":0.8700000047683716},{"id":"https://openalex.org/keywords/misdiagnosis","display_name":"misdiagnosis","score":0.7900000214576721},{"id":"https://openalex.org/keywords/liver-pathology","display_name":"liver pathology","score":0.6060000061988831},{"id":"https://openalex.org/keywords/pathophysiological-mechanisms","display_name":"pathophysiological mechanisms","score":0.6330000162124634},{"id":"https://openalex.org/keywords/treatment-strategy","display_name":"treatment options","score":0.9810000061988831}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8021000027656555},{"id":"https://openalex.org/C2777203481","wikidata":"https://www.wikidata.org/wiki/Q786844","display_name":"Autoimmune hepatitis","level":3,"score":0.6815999746322632},{"id":"https://openalex.org/C207886595","wikidata":"https://www.wikidata.org/wiki/Q1456138","display_name":"Pathological","level":2,"score":0.6463000178337097},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.506600022315979},{"id":"https://openalex.org/C45189115","wikidata":"https://www.wikidata.org/wiki/Q502159","display_name":"Serology","level":3,"score":0.43860000371932983},{"id":"https://openalex.org/C2776029263","wikidata":"https://www.wikidata.org/wiki/Q131742","display_name":"Hepatitis","level":2,"score":0.41449999809265137},{"id":"https://openalex.org/C82157600","wikidata":"https://www.wikidata.org/wiki/Q2671652","display_name":"Diagnostic test","level":2,"score":0.37689998745918274},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.36730000376701355},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.3463999927043915},{"id":"https://openalex.org/C192209626","wikidata":"https://www.wikidata.org/wiki/Q190909","display_name":"Focus (optics)","level":2,"score":0.3375000059604645},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3310000002384186},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.2842000126838684},{"id":"https://openalex.org/C2779075594","wikidata":"https://www.wikidata.org/wiki/Q8084905","display_name":"Autoimmune disease","level":3,"score":0.2818000018596649},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.26660001277923584}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:oai:pubmedcentral.nih.gov:13730783","doi":"https://doi.org/10.3760/cma.j.cn501113-20250909-00374","is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13730783/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13730783/pdf/cjh-34-10-1043.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Zhonghua Gan Zang Bing Za Zhi","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:13730783","doi":"https://doi.org/10.3760/cma.j.cn501113-20250909-00374","is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13730783/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13730783/pdf/cjh-34-10-1043.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Zhonghua Gan Zang Bing Za Zhi","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9908000230789185,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7225337963.pdf","grobid_xml":"https://content.openalex.org/works/W7225337963.grobid-xml"},"referenced_works_count":55,"referenced_works":["https://openalex.org/W1540195845","https://openalex.org/W1972663159","https://openalex.org/W1973130325","https://openalex.org/W2025240311","https://openalex.org/W2039823932","https://openalex.org/W2080662234","https://openalex.org/W2404410683","https://openalex.org/W2592783804","https://openalex.org/W2783874580","https://openalex.org/W2789956993","https://openalex.org/W2791415378","https://openalex.org/W2794410396","https://openalex.org/W2795027374","https://openalex.org/W2933038242","https://openalex.org/W3019465453","https://openalex.org/W3029347017","https://openalex.org/W3041707911","https://openalex.org/W3111795541","https://openalex.org/W3115971468","https://openalex.org/W3186102907","https://openalex.org/W3205600709","https://openalex.org/W4200029854","https://openalex.org/W4210694245","https://openalex.org/W4214482952","https://openalex.org/W4226098937","https://openalex.org/W4283321982","https://openalex.org/W4285585504","https://openalex.org/W4306654076","https://openalex.org/W4310044597","https://openalex.org/W4312130618","https://openalex.org/W4361007212","https://openalex.org/W4362676592","https://openalex.org/W4379662308","https://openalex.org/W4380450207","https://openalex.org/W4386592498","https://openalex.org/W4387358583","https://openalex.org/W4387822250","https://openalex.org/W4389285889","https://openalex.org/W4391503236","https://openalex.org/W4391723450","https://openalex.org/W4393262072","https://openalex.org/W4394961964","https://openalex.org/W4396972847","https://openalex.org/W4401267891","https://openalex.org/W4401729317","https://openalex.org/W4401960913","https://openalex.org/W4402451705","https://openalex.org/W4406138968","https://openalex.org/W4406873199","https://openalex.org/W4406939471","https://openalex.org/W4409035380","https://openalex.org/W4410329537","https://openalex.org/W4413641065","https://openalex.org/W4413921794","https://openalex.org/W4417297847"],"related_works":["https://openalex.org/W4297143766","https://openalex.org/W7217569002","https://openalex.org/W7159801741","https://openalex.org/W2731271177","https://openalex.org/W7125521321","https://openalex.org/W4403720787","https://openalex.org/W4413628511","https://openalex.org/W7214304382","https://openalex.org/W39846034","https://openalex.org/W4399812123"],"abstract_inverted_index":{"Seronegative":[0],"autoimmune":[1,14],"hepatitis":[2,15],"(snAIH)":[3],"is":[4,25],"a":[5,60,73],"liver":[6],"disease":[7],"that":[8],"meets":[9],"the":[10,32,55,64],"diagnostic":[11,33,67],"criteria":[12,34],"for":[13,27,35,75],"in":[16],"terms":[17],"of":[18,83],"clinical":[19],"manifestations":[20],"and":[21,40,49,69,78,81],"pathological":[22,65],"features":[23],"but":[24],"negative":[26],"traditional":[28],"serological":[29],"markers.":[30],"Currently,":[31],"snAIH":[36],"are":[37],"not":[38],"standardized":[39],"lack":[41],"specific":[42],"biomarkers,":[43],"thus":[44],"easily":[45],"leading":[46],"to":[47],"misdiagnosis":[48],"missed":[50],"diagnosis.":[51],"This":[52],"review":[53],"summarizes":[54],"latest":[56],"research":[57],"progress,":[58],"with":[59],"focus":[61],"on":[62],"clarifying":[63],"mechanisms,":[66],"challenges,":[68],"treatment":[70,82],"strategies,":[71],"providing":[72],"basis":[74],"timely":[76],"identification":[77],"effective":[79],"diagnosis":[80],"snAIH.":[84]},"counts_by_year":[],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2026-11-06T00:00:00"}