{"id":"https://openalex.org/W7225313372","doi":"https://doi.org/10.1002/ccr3.73835","title":"Pathological Complete Response and Successful Conversion Hepatectomy in Initially Unresectable Giant Hepatocellular Carcinoma Following Triple Therapy With HAIC , Bevacizumab, and Tislelizumab: A Case Report","display_name":"Pathological Complete Response and Successful Conversion Hepatectomy in Initially Unresectable Giant Hepatocellular Carcinoma Following Triple Therapy With HAIC , Bevacizumab, and Tislelizumab: A Case Report","publication_year":2026,"publication_date":"2026-11-01","ids":{"openalex":"https://openalex.org/W7225313372","doi":"https://doi.org/10.1002/ccr3.73835","pmid":"https://pubmed.ncbi.nlm.nih.gov/42991565","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13736232"},"language":"en","primary_location":{"id":"doi:10.1002/ccr3.73835","doi":"https://doi.org/10.1002/ccr3.73835","is_oa":true,"landing_page_url":"https://doi.org/10.1002/ccr3.73835","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ccr3.73835","source":{"id":"https://openalex.org/S2737168579","display_name":"Clinical Case Reports","issn_l":"2050-0904","issn":["2050-0904"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Case Reports","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ccr3.73835","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5160831638","display_name":"Qing Ye","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I117532281","display_name":"Guangzhou University of Chinese Medicine","ror":"https://ror.org/03qb7bg95","country_code":"CN","type":"education","lineage":["https://openalex.org/I117532281"]},{"id":"https://openalex.org/I4210105984","display_name":"Guangdong Provincial Hospital of Chinese Medicine","ror":"https://ror.org/01gb3y148","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210105984"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qing Ye","raw_affiliation_strings":["Department of Hepatobiliary Surgery Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine  Guangzhou China","The Second Clinical College of Guangzhou University of Chinese Medicine  Guangzhou China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hepatobiliary Surgery Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine  Guangzhou China","institution_ids":["https://openalex.org/I4210105984"]},{"raw_affiliation_string":"The Second Clinical College of Guangzhou University of Chinese Medicine  Guangzhou China","institution_ids":["https://openalex.org/I117532281"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037149074","display_name":"Jiamin Wang","orcid":"https://orcid.org/0000-0002-7887-9970","observed_orcids":["https://orcid.org/0000-0002-7887-9970"]},"institutions":[{"id":"https://openalex.org/I117532281","display_name":"Guangzhou University of Chinese Medicine","ror":"https://ror.org/03qb7bg95","country_code":"CN","type":"education","lineage":["https://openalex.org/I117532281"]},{"id":"https://openalex.org/I4210105984","display_name":"Guangdong Provincial Hospital of Chinese Medicine","ror":"https://ror.org/01gb3y148","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210105984"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiamin Wang","raw_affiliation_strings":["Department of Hepatobiliary Surgery Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine  Guangzhou China","The Second Clinical College of Guangzhou University of Chinese Medicine  Guangzhou China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hepatobiliary Surgery Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine  Guangzhou China","institution_ids":["https://openalex.org/I4210105984"]},{"raw_affiliation_string":"The Second Clinical College of Guangzhou University of Chinese Medicine  Guangzhou China","institution_ids":["https://openalex.org/I117532281"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030527746","display_name":"\u4f55\u519b\u660e","orcid":"https://orcid.org/0000-0001-9180-2030","observed_orcids":["https://orcid.org/0000-0001-9180-2030"]},"institutions":[{"id":"https://openalex.org/I117532281","display_name":"Guangzhou University of Chinese Medicine","ror":"https://ror.org/03qb7bg95","country_code":"CN","type":"education","lineage":["https://openalex.org/I117532281"]},{"id":"https://openalex.org/I4210105984","display_name":"Guangdong Provincial Hospital of Chinese Medicine","ror":"https://ror.org/01gb3y148","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210105984"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Junming He","raw_affiliation_strings":["Department of Hepatobiliary Surgery Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine  Guangzhou China","The Second Clinical College of Guangzhou University of Chinese Medicine  Guangzhou China"],"raw_orcid":"https://orcid.org/0000-0001-9180-2030","affiliations":[{"raw_affiliation_string":"Department of Hepatobiliary Surgery Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine  Guangzhou China","institution_ids":["https://openalex.org/I4210105984"]},{"raw_affiliation_string":"The Second Clinical College of Guangzhou University of Chinese Medicine  Guangzhou China","institution_ids":["https://openalex.org/I117532281"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160898220","display_name":"Jianxin Peng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I117532281","display_name":"Guangzhou University of Chinese Medicine","ror":"https://ror.org/03qb7bg95","country_code":"CN","type":"education","lineage":["https://openalex.org/I117532281"]},{"id":"https://openalex.org/I4210105984","display_name":"Guangdong Provincial Hospital of Chinese Medicine","ror":"https://ror.org/01gb3y148","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210105984"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianxin Peng","raw_affiliation_strings":["Department of Hepatobiliary Surgery Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine  Guangzhou China","The Second Clinical College of Guangzhou University of Chinese Medicine  Guangzhou China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hepatobiliary Surgery Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine  Guangzhou China","institution_ids":["https://openalex.org/I4210105984"]},{"raw_affiliation_string":"The Second Clinical College of Guangzhou University of Chinese Medicine  Guangzhou China","institution_ids":["https://openalex.org/I117532281"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008624944","display_name":"Huilan Zeng","orcid":"https://orcid.org/0000-0003-1701-3660","observed_orcids":["https://orcid.org/0000-0003-1701-3660","https://orcid.org/0009-0001-3274-4296"]},"institutions":[{"id":"https://openalex.org/I117532281","display_name":"Guangzhou University of Chinese Medicine","ror":"https://ror.org/03qb7bg95","country_code":"CN","type":"education","lineage":["https://openalex.org/I117532281"]},{"id":"https://openalex.org/I4210105984","display_name":"Guangdong Provincial Hospital of Chinese Medicine","ror":"https://ror.org/01gb3y148","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210105984"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Huilan Zeng","raw_affiliation_strings":["Department of Hepatobiliary Surgery Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine  Guangzhou China","The Second Clinical College of Guangzhou University of Chinese Medicine  Guangzhou China"],"raw_orcid":"https://orcid.org/0009-0001-3274-4296","affiliations":[{"raw_affiliation_string":"Department of Hepatobiliary Surgery Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine  Guangzhou China","institution_ids":["https://openalex.org/I4210105984"]},{"raw_affiliation_string":"The Second Clinical College of Guangzhou University of Chinese Medicine  Guangzhou China","institution_ids":["https://openalex.org/I117532281"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5058346366","display_name":"Jiaqiang Mo","orcid":"https://orcid.org/0009-0007-5524-5899","observed_orcids":["https://orcid.org/0009-0007-5524-5899"]},"institutions":[{"id":"https://openalex.org/I117532281","display_name":"Guangzhou University of Chinese Medicine","ror":"https://ror.org/03qb7bg95","country_code":"CN","type":"education","lineage":["https://openalex.org/I117532281"]},{"id":"https://openalex.org/I4210105984","display_name":"Guangdong Provincial Hospital of Chinese Medicine","ror":"https://ror.org/01gb3y148","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210105984"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jiaqiang Mo","raw_affiliation_strings":["Department of Hepatobiliary Surgery Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine  Guangzhou China","The Second Clinical College of Guangzhou University of Chinese Medicine  Guangzhou China"],"raw_orcid":"https://orcid.org/0009-0007-5524-5899","affiliations":[{"raw_affiliation_string":"Department of Hepatobiliary Surgery Guangdong Provincial Hospital of Chinese Medicine, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine  Guangzhou China","institution_ids":["https://openalex.org/I4210105984"]},{"raw_affiliation_string":"The Second Clinical College of Guangzhou University of Chinese Medicine  Guangzhou China","institution_ids":["https://openalex.org/I117532281"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5008624944","https://openalex.org/A5058346366"],"corresponding_institution_ids":["https://openalex.org/I117532281","https://openalex.org/I4210105984"],"apc_list":{"value":1820,"currency":"USD","value_usd":1820},"apc_paid":{"value":1820,"currency":"USD","value_usd":1820},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.82235393,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"14","issue":"11","first_page":"e73835","last_page":"e73835"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10073","display_name":"Hepatocellular Carcinoma Treatment and Prognosis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10073","display_name":"Hepatocellular Carcinoma Treatment and Prognosis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11067","display_name":"Colorectal Cancer Treatments and Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10449","display_name":"Renal cell carcinoma treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/giant-hepatocellular-carcinoma","display_name":"giant hepatocellular carcinoma","score":0.9129999876022339},{"id":"https://openalex.org/keywords/unresectable-liver-cancer","display_name":"unresectable liver cancer","score":0.8199999928474426},{"id":"https://openalex.org/keywords/pathological-complete-response","display_name":"pathological complete response","score":0.8830000162124634},{"id":"https://openalex.org/keywords/bevacizumab","display_name":"bevacizumab","score":0.9879999756813049},{"id":"https://openalex.org/keywords/tislelizumab","display_name":"tislelizumab","score":0.9980000257492065},{"id":"https://openalex.org/keywords/triple-therapy","display_name":"triple therapy","score":0.6299999952316284},{"id":"https://openalex.org/keywords/future-liver-remnant","display_name":"future liver remnant","score":0.8019999861717224},{"id":"https://openalex.org/keywords/alpha-fetoprotein","display_name":"alpha-fetoprotein","score":0.7739999890327454},{"id":"https://openalex.org/keywords/immunotherapy","display_name":"immunotherapy","score":0.45500001311302185}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9398000240325928},{"id":"https://openalex.org/C21613296","wikidata":"https://www.wikidata.org/wiki/Q4925405","display_name":"Coagulative necrosis","level":2,"score":0.7882000207901001},{"id":"https://openalex.org/C2778019345","wikidata":"https://www.wikidata.org/wiki/Q1148337","display_name":"Hepatocellular carcinoma","level":2,"score":0.7045999765396118},{"id":"https://openalex.org/C3019096185","wikidata":"https://www.wikidata.org/wiki/Q1340863","display_name":"Complete response","level":3,"score":0.6607000231742859},{"id":"https://openalex.org/C2779984678","wikidata":"https://www.wikidata.org/wiki/Q2145898","display_name":"Response Evaluation Criteria in Solid Tumors","level":4,"score":0.6398000121116638},{"id":"https://openalex.org/C207886595","wikidata":"https://www.wikidata.org/wiki/Q1456138","display_name":"Pathological","level":2,"score":0.6396999955177307},{"id":"https://openalex.org/C544855455","wikidata":"https://www.wikidata.org/wiki/Q1070952","display_name":"Histopathology","level":2,"score":0.6069999933242798},{"id":"https://openalex.org/C2776909242","wikidata":"https://www.wikidata.org/wiki/Q1514021","display_name":"Hepatectomy","level":3,"score":0.5963000059127808},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.5242999792098999},{"id":"https://openalex.org/C2779033008","wikidata":"https://www.wikidata.org/wiki/Q464543","display_name":"Portal vein","level":2,"score":0.4171999990940094},{"id":"https://openalex.org/C159110652","wikidata":"https://www.wikidata.org/wiki/Q17078201","display_name":"Resection","level":2,"score":0.39730000495910645},{"id":"https://openalex.org/C2777546739","wikidata":"https://www.wikidata.org/wiki/Q33525","display_name":"Carcinoma","level":2,"score":0.3158999979496002},{"id":"https://openalex.org/C3020562746","wikidata":"https://www.wikidata.org/wiki/Q7446275","display_name":"Surgical resection","level":2,"score":0.3109999895095825},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.30809998512268066},{"id":"https://openalex.org/C2777202286","wikidata":"https://www.wikidata.org/wiki/Q9609","display_name":"Vein","level":2,"score":0.305400013923645},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2858999967575073},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.2824999988079071},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.28040000796318054},{"id":"https://openalex.org/C2778292576","wikidata":"https://www.wikidata.org/wiki/Q6991934","display_name":"Neoadjuvant therapy","level":4,"score":0.27250000834465027},{"id":"https://openalex.org/C2776964913","wikidata":"https://www.wikidata.org/wiki/Q1671502","display_name":"Liver tumor","level":3,"score":0.25699999928474426},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.2526000142097473},{"id":"https://openalex.org/C544519230","wikidata":"https://www.wikidata.org/wiki/Q32566","display_name":"Computed tomography","level":2,"score":0.2524999976158142}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1002/ccr3.73835","doi":"https://doi.org/10.1002/ccr3.73835","is_oa":true,"landing_page_url":"https://doi.org/10.1002/ccr3.73835","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ccr3.73835","source":{"id":"https://openalex.org/S2737168579","display_name":"Clinical Case Reports","issn_l":"2050-0904","issn":["2050-0904"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Case Reports","raw_type":"journal-article"},{"id":"pmid:42991565","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42991565","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical case reports","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13736232","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13736232/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clin Case Rep","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:d7aa7bbee2f346df982512a2c82ea6ee","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/d7aa7bbee2f346df982512a2c82ea6ee","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Clinical Case Reports, Vol 14, Iss 11, Pp n/a-n/a (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1002/ccr3.73835","doi":"https://doi.org/10.1002/ccr3.73835","is_oa":true,"landing_page_url":"https://doi.org/10.1002/ccr3.73835","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ccr3.73835","source":{"id":"https://openalex.org/S2737168579","display_name":"Clinical Case Reports","issn_l":"2050-0904","issn":["2050-0904"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Case Reports","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7225313372.pdf","grobid_xml":"https://content.openalex.org/works/W7225313372.grobid-xml"},"referenced_works_count":13,"referenced_works":["https://openalex.org/W2078479400","https://openalex.org/W2157676683","https://openalex.org/W2373606074","https://openalex.org/W2997466314","https://openalex.org/W3000125713","https://openalex.org/W3025022288","https://openalex.org/W4405436927","https://openalex.org/W4405816356","https://openalex.org/W4408509785","https://openalex.org/W4409725650","https://openalex.org/W4410536169","https://openalex.org/W7151446370","https://openalex.org/W7152572017"],"related_works":["https://openalex.org/W7219739013","https://openalex.org/W7151446370","https://openalex.org/W7204115608","https://openalex.org/W4388139285","https://openalex.org/W3048539348","https://openalex.org/W4200211413","https://openalex.org/W7224087582","https://openalex.org/W7161484666","https://openalex.org/W2339710761","https://openalex.org/W4322489315"],"abstract_inverted_index":{"Severe":[0],"future":[1],"liver":[2,42],"remnant":[3],"(FLR)":[4],"deficiency":[5],"frequently":[6],"renders":[7],"giant":[8,22],"hepatocellular":[9],"carcinoma":[10],"(HCC)":[11],"unresectable.":[12],"We":[13],"report":[14],"a":[15,77,95,139,153,203],"48-year-old":[16],"man":[17],"with":[18,39,150],"an":[19,35,40,105,116],"unresectable":[20],"23.5-cm":[21],"HCC":[23],"(Couinaud":[24],"segments":[25],"4/5/8;":[26],"baseline":[27],"serum":[28,162],"alpha-fetoprotein":[29],"(AFP),":[30],"1036.65":[31],"\u03bcg/L).":[32],"Initially":[33],"requiring":[34],"extended":[36],"right":[37,132,142,198],"trisectionectomy":[38],"FLR/standard":[41],"volume":[43,109,191],"(SLV)":[44],"ratio":[45],"of":[46,54],"only":[47],"36.58%":[48],"(450":[49],"mL).":[50],"Following":[51],"three":[52],"cycles":[53],"mFOLFOX-HAIC,":[55],"bevacizumab,":[56],"and":[57,94,115,128,168,192],"tislelizumab,":[58],"restaging":[59],"computed":[60],"tomography":[61],"(CT)":[62],"showed":[63],"tumor":[64,123,180],"regression":[65,181],"to":[66,76,82,100,110,119,138,165],"9.0":[67],"cm":[68],"in":[69,87,107],"maximum":[70],"diameter":[71],"(a":[72],"61.7%":[73],"reduction),":[74],"corresponding":[75],"partial":[78],"response":[79,97,156],"(PR)":[80],"according":[81,99],"the":[83,101,131,169,197],"Response":[84],"Evaluation":[85],"Criteria":[86],"Solid":[88],"Tumors,":[89],"version":[90],"1.1":[91],"(RECIST":[92],"1.1),":[93],"complete":[96,155],"(CR)":[98],"modified":[102],"RECIST":[103],"(mRECIST),":[104],"increase":[106],"FLR":[108,190],"733":[111],"mL":[112],"(FLR/SLV:":[113],"59.58%),":[114],"AFP":[117,163],"decline":[118],"115.00":[120],"\u03bcg/L.":[121],"Crucially,":[122],"clearance":[124],"from":[125,130,196],"segment":[126],"4":[127],"separation":[129,195],"portal":[133,199,208],"pedicle":[134],"enabled":[135],"surgical":[136],"downstaging":[137],"parenchymal-sparing":[140],"anatomical":[141,194],"anterior":[143],"sectionectomy":[144],"(S5/8).":[145],"R0":[146],"resection":[147,206],"was":[148],"achieved,":[149],"histopathology":[151],"confirming":[152],"pathological":[154],"(pCR;":[157],"100%":[158],"coagulative":[159],"necrosis).":[160],"Postoperatively,":[161],"normalized":[164],"5.60":[166],"\u03bcg/L,":[167],"patient":[170],"remains":[171],"recurrence-free":[172],"at":[173],"22":[174],"months.":[175],"This":[176],"case":[177],"illustrates":[178],"that":[179],"during":[182],"triple":[183],"therapy":[184],"may":[185],"be":[186],"accompanied":[187],"by":[188],"increased":[189],"improved":[193],"pedicle,":[200],"potentially":[201],"enabling":[202],"more":[204],"limited":[205],"without":[207],"vein":[209],"embolization.":[210]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2026-11-06T00:00:00"}
