{"id":"https://openalex.org/W7225273063","doi":"https://doi.org/10.3389/fmed.2026.1869730","title":"Factors associated with graft rejection after penetrating keratoplasty in mechanical corneal injury","display_name":"Factors associated with graft rejection after penetrating keratoplasty in mechanical corneal injury","publication_year":2026,"publication_date":"2026-11-04","ids":{"openalex":"https://openalex.org/W7225273063","doi":"https://doi.org/10.3389/fmed.2026.1869730"},"language":"en","primary_location":{"id":"doi:10.3389/fmed.2026.1869730","doi":"https://doi.org/10.3389/fmed.2026.1869730","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fmed.2026.1869730","pdf_url":"https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2026.1869730/pdf","source":{"id":"https://openalex.org/S2597052008","display_name":"Frontiers in Medicine","issn_l":"2296-858X","issn":["2296-858X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2026.1869730/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5128327393","display_name":"Zhijian Zhang","orcid":"https://orcid.org/0009-0001-5441-532X","observed_orcids":["https://orcid.org/0009-0001-5441-532X"]},"institutions":[{"id":"https://openalex.org/I191996457","display_name":"Dalian Medical University","ror":"https://ror.org/04c8eg608","country_code":"CN","type":"education","lineage":["https://openalex.org/I191996457"]},{"id":"https://openalex.org/I4210108983","display_name":"The Third People's Hospital of Dalian City","ror":"https://ror.org/01kr9ze74","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210108983"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhijian Zhang","raw_affiliation_strings":["Dalian Medical University","Department of Ophthalmology, Third People\u2019s Hospital of Dalian"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dalian Medical University","institution_ids":["https://openalex.org/I191996457"]},{"raw_affiliation_string":"Department of Ophthalmology, Third People\u2019s Hospital of Dalian","institution_ids":["https://openalex.org/I4210108983"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047857548","display_name":"Chunxiao Yan","orcid":"https://orcid.org/0000-0002-8134-8169","observed_orcids":["https://orcid.org/0000-0002-8134-8169"]},"institutions":[{"id":"https://openalex.org/I4210108983","display_name":"The Third People's Hospital of Dalian City","ror":"https://ror.org/01kr9ze74","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210108983"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chunxiao Yan","raw_affiliation_strings":["Department of Ophthalmology, Third People\u2019s Hospital of Dalian"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, Third People\u2019s Hospital of Dalian","institution_ids":["https://openalex.org/I4210108983"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160630481","display_name":"Yao Xiang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I191996457","display_name":"Dalian Medical University","ror":"https://ror.org/04c8eg608","country_code":"CN","type":"education","lineage":["https://openalex.org/I191996457"]},{"id":"https://openalex.org/I4210108983","display_name":"The Third People's Hospital of Dalian City","ror":"https://ror.org/01kr9ze74","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210108983"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yao Xiang","raw_affiliation_strings":["Dalian Medical University","Department of Ophthalmology, Third People\u2019s Hospital of Dalian"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dalian Medical University","institution_ids":["https://openalex.org/I191996457"]},{"raw_affiliation_string":"Department of Ophthalmology, Third People\u2019s Hospital of Dalian","institution_ids":["https://openalex.org/I4210108983"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160644119","display_name":"Lin Jin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210108983","display_name":"The Third People's Hospital of Dalian City","ror":"https://ror.org/01kr9ze74","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210108983"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lin Jin","raw_affiliation_strings":["Department of Ophthalmology, Third People\u2019s Hospital of Dalian"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, Third People\u2019s Hospital of Dalian","institution_ids":["https://openalex.org/I4210108983"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5126473377","display_name":"He Dong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210108983","display_name":"The Third People's Hospital of Dalian City","ror":"https://ror.org/01kr9ze74","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210108983"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"He Dong","raw_affiliation_strings":["Department of Ophthalmology, Third People\u2019s Hospital of Dalian"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, Third People\u2019s Hospital of Dalian","institution_ids":["https://openalex.org/I4210108983"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160624159","display_name":"Lei Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210145693","display_name":"Guangdong Academy of Medical Sciences","ror":"https://ror.org/0432p8t34","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210145693"]},{"id":"https://openalex.org/I4210153930","display_name":"Guangdong Provincial People's Hospital","ror":"https://ror.org/045kpgw45","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153930"]},{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Lei Liu","raw_affiliation_strings":["Department of Ophthalmology, Guangdong Eye Institute, Guangdong Provincial People\u2019s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, Guangdong Eye Institute, Guangdong Provincial People\u2019s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University","institution_ids":["https://openalex.org/I4210145693","https://openalex.org/I4210153930","https://openalex.org/I58200834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089995581","display_name":"Chuanfeng An","orcid":"https://orcid.org/0000-0002-5074-3094","observed_orcids":["https://orcid.org/0000-0002-5074-3094"]},"institutions":[{"id":"https://openalex.org/I27357992","display_name":"Dalian University of Technology","ror":"https://ror.org/023hj5876","country_code":"CN","type":"education","lineage":["https://openalex.org/I27357992"]},{"id":"https://openalex.org/I4210108983","display_name":"The Third People's Hospital of Dalian City","ror":"https://ror.org/01kr9ze74","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210108983"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Chuanfeng An","raw_affiliation_strings":["Department of Ophthalmology, Third People\u2019s Hospital of Dalian","Ophthalmology and Transformational Innovation Research Center, Faculty of Medicine of Dalian University of Technology&Dalian Third People\u2019s Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, Third People\u2019s Hospital of Dalian","institution_ids":["https://openalex.org/I4210108983"]},{"raw_affiliation_string":"Ophthalmology and Transformational Innovation Research Center, Faculty of Medicine of Dalian University of Technology&Dalian Third People\u2019s Hospital","institution_ids":["https://openalex.org/I27357992","https://openalex.org/I4210108983"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5160658257","display_name":"Lijun Zhang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I191996457","display_name":"Dalian Medical University","ror":"https://ror.org/04c8eg608","country_code":"CN","type":"education","lineage":["https://openalex.org/I191996457"]},{"id":"https://openalex.org/I27357992","display_name":"Dalian University of Technology","ror":"https://ror.org/023hj5876","country_code":"CN","type":"education","lineage":["https://openalex.org/I27357992"]},{"id":"https://openalex.org/I4210108983","display_name":"The Third People's Hospital of Dalian City","ror":"https://ror.org/01kr9ze74","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210108983"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Lijun Zhang","raw_affiliation_strings":["Dalian Medical University","Department of Ophthalmology, Third People\u2019s Hospital of Dalian","Ophthalmology and Transformational Innovation Research Center, Faculty of Medicine of Dalian University of Technology&Dalian Third People\u2019s Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dalian Medical University","institution_ids":["https://openalex.org/I191996457"]},{"raw_affiliation_string":"Department of Ophthalmology, Third People\u2019s Hospital of Dalian","institution_ids":["https://openalex.org/I4210108983"]},{"raw_affiliation_string":"Ophthalmology and Transformational Innovation Research Center, Faculty of Medicine of Dalian University of Technology&Dalian Third People\u2019s Hospital","institution_ids":["https://openalex.org/I27357992","https://openalex.org/I4210108983"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5089995581","https://openalex.org/A5160624159","https://openalex.org/A5160658257"],"corresponding_institution_ids":["https://openalex.org/I191996457","https://openalex.org/I27357992","https://openalex.org/I4210108983","https://openalex.org/I4210145693","https://openalex.org/I4210153930","https://openalex.org/I58200834"],"apc_list":{"value":3150,"currency":"CHF","value_usd":3801},"apc_paid":{"value":3150,"currency":"CHF","value_usd":3801},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.90424447,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":null,"biblio":{"volume":"13","issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10563","display_name":"Corneal surgery and disorders","score":0.9672999978065491,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10563","display_name":"Corneal surgery and disorders","score":0.9672999978065491,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11828","display_name":"Corneal Surgery and Treatments","score":0.022299999371170998,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11867","display_name":"Traumatic Ocular and Foreign Body Injuries","score":0.006000000052154064,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/penetrating-keratoplasty","display_name":"penetrating keratoplasty","score":0.9049999713897705},{"id":"https://openalex.org/keywords/graft-rejection","display_name":"graft rejection","score":0.9620000123977661},{"id":"https://openalex.org/keywords/corneal-ulcer","display_name":"corneal ulcer","score":0.7990000247955322},{"id":"https://openalex.org/keywords/preoperative-treatment","display_name":"preoperative treatment","score":0.9459999799728394},{"id":"https://openalex.org/keywords/corneal-neovascularization","display_name":"corneal neovascularization","score":0.9739999771118164},{"id":"https://openalex.org/keywords/corneal-fibrosis","display_name":"corneal fibrosis","score":0.9879999756813049},{"id":"https://openalex.org/keywords/corneal-edema","display_name":"corneal edema","score":1.0},{"id":"https://openalex.org/keywords/risk-factors","display_name":"risk factors","score":0.9419999718666077},{"id":"https://openalex.org/keywords/risk-prediction-model","display_name":"risk prediction model","score":0.5989999771118164},{"id":"https://openalex.org/keywords/corneal-transplantation","display_name":"corneal transplantation","score":0.7480000257492065}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9538000226020813},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.5774999856948853},{"id":"https://openalex.org/C31174226","wikidata":"https://www.wikidata.org/wiki/Q64855140","display_name":"Perioperative","level":2,"score":0.553600013256073},{"id":"https://openalex.org/C2780686511","wikidata":"https://www.wikidata.org/wiki/Q579361","display_name":"Corneal transplantation","level":3,"score":0.4787999987602234},{"id":"https://openalex.org/C3017636755","wikidata":"https://www.wikidata.org/wiki/Q168291","display_name":"Corneal disease","level":3,"score":0.45339998602867126},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.43479999899864197},{"id":"https://openalex.org/C144301174","wikidata":"https://www.wikidata.org/wiki/Q7893852","display_name":"Univariate analysis","level":3,"score":0.4198000133037567},{"id":"https://openalex.org/C2909270721","wikidata":"https://www.wikidata.org/wiki/Q579361","display_name":"Corneal Transplant","level":4,"score":0.41269999742507935},{"id":"https://openalex.org/C207886595","wikidata":"https://www.wikidata.org/wiki/Q1456138","display_name":"Pathological","level":2,"score":0.4011000096797943},{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.3921999931335449},{"id":"https://openalex.org/C2910338442","wikidata":"https://www.wikidata.org/wiki/Q579361","display_name":"Corneal graft","level":3,"score":0.38749998807907104},{"id":"https://openalex.org/C2780886150","wikidata":"https://www.wikidata.org/wiki/Q152234","display_name":"Edema","level":2,"score":0.38499999046325684},{"id":"https://openalex.org/C58471807","wikidata":"https://www.wikidata.org/wiki/Q327120","display_name":"Receiver operating characteristic","level":2,"score":0.34299999475479126},{"id":"https://openalex.org/C2776882836","wikidata":"https://www.wikidata.org/wiki/Q168291","display_name":"Cornea","level":2,"score":0.3409999907016754},{"id":"https://openalex.org/C2777844972","wikidata":"https://www.wikidata.org/wiki/Q1266519","display_name":"Corneal neovascularization","level":4,"score":0.3192000091075897},{"id":"https://openalex.org/C2778271429","wikidata":"https://www.wikidata.org/wiki/Q1281049","display_name":"Neovascularization","level":3,"score":0.3154999911785126},{"id":"https://openalex.org/C2776148792","wikidata":"https://www.wikidata.org/wiki/Q3041498","display_name":"Eye disease","level":2,"score":0.30799999833106995},{"id":"https://openalex.org/C2780559512","wikidata":"https://www.wikidata.org/wiki/Q605709","display_name":"Fibrosis","level":2,"score":0.2946000099182129},{"id":"https://openalex.org/C3019230761","wikidata":"https://www.wikidata.org/wiki/Q1765748","display_name":"Graft rejection","level":3,"score":0.28760001063346863},{"id":"https://openalex.org/C50440223","wikidata":"https://www.wikidata.org/wiki/Q1475848","display_name":"Risk factor","level":2,"score":0.2660999894142151},{"id":"https://openalex.org/C81182388","wikidata":"https://www.wikidata.org/wiki/Q353963","display_name":"Complication","level":2,"score":0.2619999945163727},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.26159998774528503}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.3389/fmed.2026.1869730","doi":"https://doi.org/10.3389/fmed.2026.1869730","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fmed.2026.1869730","pdf_url":"https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2026.1869730/pdf","source":{"id":"https://openalex.org/S2597052008","display_name":"Frontiers in Medicine","issn_l":"2296-858X","issn":["2296-858X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Medicine","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.3389/fmed.2026.1869730","doi":"https://doi.org/10.3389/fmed.2026.1869730","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fmed.2026.1869730","pdf_url":"https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2026.1869730/pdf","source":{"id":"https://openalex.org/S2597052008","display_name":"Frontiers in Medicine","issn_l":"2296-858X","issn":["2296-858X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7225273063.pdf","grobid_xml":"https://content.openalex.org/works/W7225273063.grobid-xml"},"referenced_works_count":17,"referenced_works":["https://openalex.org/W1669660972","https://openalex.org/W2077031591","https://openalex.org/W2153960140","https://openalex.org/W2181511066","https://openalex.org/W2323420755","https://openalex.org/W2910491228","https://openalex.org/W2938167752","https://openalex.org/W2955238053","https://openalex.org/W3036721396","https://openalex.org/W3048354482","https://openalex.org/W3182242395","https://openalex.org/W4206833529","https://openalex.org/W4281985799","https://openalex.org/W4283274588","https://openalex.org/W4377043757","https://openalex.org/W4388982365","https://openalex.org/W4408922156"],"related_works":["https://openalex.org/W2370872182","https://openalex.org/W1986227272","https://openalex.org/W2348539815","https://openalex.org/W4400083968","https://openalex.org/W4403103755","https://openalex.org/W2090382503","https://openalex.org/W2065979897","https://openalex.org/W4280595255","https://openalex.org/W3029604109","https://openalex.org/W2073826009"],"abstract_inverted_index":{"Purpose":[0],"To":[1],"investigate":[2],"factors":[3,142],"associated":[4,82,95],"with":[5,13,29,83,96,149],"graft":[6,89,145],"rejection":[7,146],"after":[8],"penetrating":[9,35],"keratoplasty":[10,36],"in":[11,147],"patients":[12,28,148],"mechanical":[14,30,150],"corneal":[15,31,49,79,104,110,137,151,154],"injury":[16,32,152],"and":[17,39,48,55,65,77,106,135,165,187],"evaluate":[18],"their":[19],"predictive":[20],"value.":[21],"Methods":[22],"This":[23],"retrospective":[24],"study":[25],"included":[26],"50":[27],"who":[33],"underwent":[34],"between":[37],"2019":[38],"2025.":[40],"Clinical":[41],"variables,":[42],"including":[43],"onset":[44,75,102,133],"duration,":[45,103],"preoperative":[46,78,92,136,157,184],"treatment,":[47],"pathological":[50],"changes,":[51],"were":[52,71,81,119],"analyzed.":[53],"Univariate":[54],"multivariable":[56],"logistic":[57],"regression,":[58],"time-to-event":[59],"analysis,":[60,62,64],"stratified":[61],"mediation":[63],"receiver":[66],"operating":[67],"characteristic":[68],"curve":[69],"analysis":[70,114],"performed.":[72],"Results":[73],"Prolonged":[74,132],"duration":[76,134],"ulceration":[80,138],"an":[84],"increased":[85],"risk":[86,141,185],"of":[87,170],"postoperative":[88,144],"rejection,":[90],"whereas":[91,109,156],"treatment":[93,158],"was":[94],"a":[97,181],"reduced":[98],"risk.":[99],"With":[100],"increasing":[101],"neovascularization":[105],"fibrosis":[107],"increased,":[108],"edema":[111],"decreased.":[112],"Mediation":[113],"showed":[115],"that":[116],"these":[117],"associations":[118],"mainly":[120],"driven":[121],"by":[122],"direct":[123],"effects.":[124],"Prediction":[125],"models":[126],"demonstrated":[127],"good":[128],"discriminatory":[129],"performance.":[130],"Conclusions":[131],"may":[139,159,179],"be":[140,160],"for":[143,173,183],"undergoing":[153],"transplantation,":[155],"protective.":[161],"Therefore,":[162],"early":[163],"intervention":[164],"disease":[166],"course":[167],"control":[168],"are":[169],"great":[171],"importance":[172],"improving":[174],"transplant":[175],"prognosis.":[176],"These":[177],"findings":[178],"provide":[180],"reference":[182],"stratification":[186],"perioperative":[188],"management.":[189]},"counts_by_year":[],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2026-11-05T00:00:00"}