{"id":"https://openalex.org/W7225259642","doi":"https://doi.org/10.5281/zenodo.23964259","title":"Carcinoma hepatocelular en pacientes con enfermedad hep\u00e1tica cr\u00f3nica de etiolog\u00eda etan\u00f3lica","display_name":"Carcinoma hepatocelular en pacientes con enfermedad hep\u00e1tica cr\u00f3nica de etiolog\u00eda etan\u00f3lica","publication_year":2019,"publication_date":"2019-03-01","ids":{"openalex":"https://openalex.org/W7225259642","doi":"https://doi.org/10.5281/zenodo.23964259"},"language":"es","primary_location":{"id":"doi:10.5281/zenodo.23964259","doi":"https://doi.org/10.5281/zenodo.23964259","is_oa":true,"landing_page_url":"https://doi.org/10.5281/zenodo.23964259","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"BookChapter"},"volume":null,"type":"book-chapter","is_traditional":true,"indexed_in":["datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doi.org/10.5281/zenodo.23964259","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5013407828","display_name":"Mykhailo Iashchuk","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405258974","display_name":"Hospital de Santa Luzia de Elvas","ror":"https://ror.org/01gejfk39","country_code":"PT","type":"healthcare","lineage":["https://openalex.org/I4405258974"]}],"countries":["PT"],"is_corresponding":true,"raw_author_name":"Iashchuk, Mykhailo","raw_affiliation_strings":["Hospital de Santa Luzia de Elvas"],"raw_orcid":"https://orcid.org/0000-0003-1463-6336","affiliations":[{"raw_affiliation_string":"Hospital de Santa Luzia de Elvas","institution_ids":["https://openalex.org/I4405258974"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5013407828"],"corresponding_institution_ids":["https://openalex.org/I4405258974"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10073","display_name":"Hepatocellular Carcinoma Treatment and Prognosis","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10073","display_name":"Hepatocellular Carcinoma Treatment and Prognosis","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11207","display_name":"Alcohol Consumption and Health Effects","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10966","display_name":"Liver physiology and pathology","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hepatocellular-carcinoma","display_name":"hepatocellular carcinoma","score":1.0},{"id":"https://openalex.org/keywords/alcoholic-liver-disease","display_name":"alcoholic liver disease","score":0.7710000276565552},{"id":"https://openalex.org/keywords/alcoholic-cirrhosis","display_name":"alcoholic cirrhosis","score":0.9100000262260437},{"id":"https://openalex.org/keywords/portal-hypertension","display_name":"portal hypertension","score":0.8730000257492065},{"id":"https://openalex.org/keywords/esophageal-varices","display_name":"esophageal varices","score":0.8840000033378601},{"id":"https://openalex.org/keywords/alpha-fetoprotein","display_name":"alpha-fetoprotein","score":0.9419999718666077},{"id":"https://openalex.org/keywords/portal-vein-thrombosis","display_name":"portal vein thrombosis","score":0.9290000200271606},{"id":"https://openalex.org/keywords/multifocal-liver-lesions","display_name":"multifocal liver lesions","score":0.6230000257492065},{"id":"https://openalex.org/keywords/contrast-enhanced-mri","display_name":"contrast-enhanced MRI","score":0.671999990940094},{"id":"https://openalex.org/keywords/liver-ultrasound","display_name":"liver ultrasound","score":0.6759999990463257},{"id":"https://openalex.org/keywords/liver-cancer-surveillance","display_name":"liver cancer surveillance","score":0.6359999775886536}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9509000182151794},{"id":"https://openalex.org/C2778019345","wikidata":"https://www.wikidata.org/wiki/Q1148337","display_name":"Hepatocellular carcinoma","level":2,"score":0.7286999821662903},{"id":"https://openalex.org/C2778800853","wikidata":"https://www.wikidata.org/wiki/Q1704044","display_name":"Portal vein thrombosis","level":3,"score":0.6028000116348267},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.5848000049591064},{"id":"https://openalex.org/C2779102576","wikidata":"https://www.wikidata.org/wiki/Q5113984","display_name":"Chronic liver disease","level":3,"score":0.5419999957084656},{"id":"https://openalex.org/C81182388","wikidata":"https://www.wikidata.org/wiki/Q353963","display_name":"Complication","level":2,"score":0.5223000049591064},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.5174000263214111},{"id":"https://openalex.org/C2777655228","wikidata":"https://www.wikidata.org/wiki/Q590460","display_name":"Abdominal ultrasonography","level":3,"score":0.4652000069618225},{"id":"https://openalex.org/C2777546739","wikidata":"https://www.wikidata.org/wiki/Q33525","display_name":"Carcinoma","level":2,"score":0.41350001096725464},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.4011000096797943},{"id":"https://openalex.org/C2778808290","wikidata":"https://www.wikidata.org/wiki/Q124604","display_name":"Portal hypertension","level":3,"score":0.39239999651908875},{"id":"https://openalex.org/C2777075537","wikidata":"https://www.wikidata.org/wiki/Q929737","display_name":"Liver disease","level":2,"score":0.34619998931884766},{"id":"https://openalex.org/C529618451","wikidata":"https://www.wikidata.org/wiki/Q234904","display_name":"Ultrasonography","level":2,"score":0.34150001406669617},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3370000123977661},{"id":"https://openalex.org/C2776231280","wikidata":"https://www.wikidata.org/wiki/Q623031","display_name":"Liver cancer","level":3,"score":0.3149999976158142},{"id":"https://openalex.org/C2780639617","wikidata":"https://www.wikidata.org/wiki/Q6516972","display_name":"Quadrant (abdomen)","level":2,"score":0.2928999960422516},{"id":"https://openalex.org/C2779033008","wikidata":"https://www.wikidata.org/wiki/Q464543","display_name":"Portal vein","level":2,"score":0.2777999937534332},{"id":"https://openalex.org/C2777595160","wikidata":"https://www.wikidata.org/wiki/Q298278","display_name":"Esophageal varices","level":4,"score":0.25859999656677246},{"id":"https://openalex.org/C2780868729","wikidata":"https://www.wikidata.org/wiki/Q261327","display_name":"Thrombosis","level":2,"score":0.2583000063896179},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.25459998846054077},{"id":"https://openalex.org/C2777214474","wikidata":"https://www.wikidata.org/wiki/Q147778","display_name":"Cirrhosis","level":2,"score":0.25450000166893005}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.5281/zenodo.23964259","doi":"https://doi.org/10.5281/zenodo.23964259","is_oa":true,"landing_page_url":"https://doi.org/10.5281/zenodo.23964259","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"BookChapter"},{"id":"doi:10.5281/zenodo.23964260","doi":"https://doi.org/10.5281/zenodo.23964260","is_oa":true,"landing_page_url":"https://doi.org/10.5281/zenodo.23964260","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"BookChapter"}],"best_oa_location":{"id":"doi:10.5281/zenodo.23964259","doi":"https://doi.org/10.5281/zenodo.23964259","is_oa":true,"landing_page_url":"https://doi.org/10.5281/zenodo.23964259","pdf_url":null,"source":{"id":"https://openalex.org/S4306400562","display_name":"Zenodo (CERN European Organization for Nuclear Research)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I67311998","host_organization_name":"European Organization for Nuclear Research","host_organization_lineage":["https://openalex.org/I67311998"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"BookChapter"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4401811201","https://openalex.org/W2979018111","https://openalex.org/W2317552420","https://openalex.org/W4413468307","https://openalex.org/W7124285082","https://openalex.org/W2444565993","https://openalex.org/W2991895073","https://openalex.org/W3181592163","https://openalex.org/W2322293433","https://openalex.org/W4407459087"],"abstract_inverted_index":{"Background:":[0],"Hepatocellular":[1],"carcinoma":[2,121],"(HCC)":[3],"is":[4],"a":[5,28],"major":[6],"complication":[7],"of":[8,71,82,119,133,149,155],"chronic":[9,34,162],"liver":[10,35,64,127,163],"disease,":[11,36],"including":[12],"alcohol-related":[13,33,126],"cirrhosis.":[14],"Early":[15],"recognition":[16],"and":[17,41,56,67,80,102,129,136,151],"appropriate":[18],"imaging":[19,87,135],"are":[20],"essential":[21],"for":[22],"diagnosis.":[23],"Case":[24],"presentation:":[25],"We":[26],"describe":[27],"67-year-old":[29],"male":[30],"patient":[31],"with":[32,46,98,124,161],"portal":[37,83,103,110],"hypertension,":[38],"esophageal":[39],"varices,":[40],"hypertensive":[42],"gastropathy":[43],"who":[44],"presented":[45],"right":[47],"upper":[48],"quadrant":[49],"abdominal":[50,57],"pain,":[51],"jaundice,":[52],"weight":[53],"loss,":[54],"fatigue,":[55],"distension.":[58],"Laboratory":[59],"investigations":[60],"revealed":[61],"hyperbilirubinemia,":[62],"elevated":[63],"enzymes,":[65],"hypoalbuminemia,":[66],"an":[68],"alpha-fetoprotein":[69,137],"concentration":[70],"411":[72],"ng/mL.":[73],"Abdominal":[74],"ultrasonography":[75],"demonstrated":[76],"multiple":[77,91],"hepatic":[78,95,157],"nodules":[79],"features":[81],"hypertension.":[84],"Magnetic":[85],"resonance":[86],"confirmed":[88],"established":[89],"cirrhosis,":[90],"lesions":[92,158],"in":[93,122,139,159],"both":[94],"lobes":[96],"compatible":[97],"multifocal":[99],"hepatocellular":[100,120],"carcinoma,":[101],"vein":[104],"thrombosis":[105],"extending":[106],"into":[107],"the":[108,116,131,140,147],"main":[109],"trunk.":[111],"Discussion:":[112],"This":[113],"case":[114,145],"illustrates":[115],"diagnostic":[117,141,153],"challenges":[118],"patients":[123,160],"advanced":[125],"disease":[128],"highlights":[130],"role":[132],"contrast-enhanced":[134],"assessment":[138],"evaluation.":[142],"Conclusion:":[143],"The":[144],"emphasizes":[146],"importance":[148],"surveillance":[150],"timely":[152],"investigation":[154],"suspicious":[156],"disease.":[164]},"counts_by_year":[],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2026-11-05T00:00:00"}