{"id":"https://openalex.org/W7225247004","doi":"https://doi.org/10.1093/jscr/rjag991","title":"Diagnostic challenge in distinguishing intestinal endometriosis-associated carcinoma from primary colorectal adenocarcinoma: a case report","display_name":"Diagnostic challenge in distinguishing intestinal endometriosis-associated carcinoma from primary colorectal adenocarcinoma: a case report","publication_year":2026,"publication_date":"2026-11-01","ids":{"openalex":"https://openalex.org/W7225247004","doi":"https://doi.org/10.1093/jscr/rjag991","pmid":"https://pubmed.ncbi.nlm.nih.gov/42984604","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13731195"},"language":"en","primary_location":{"id":"doi:10.1093/jscr/rjag991","doi":"https://doi.org/10.1093/jscr/rjag991","is_oa":true,"landing_page_url":"https://doi.org/10.1093/jscr/rjag991","pdf_url":"https://academic.oup.com/jscr/article-pdf/2026/11/rjag991/72931852/rjag991.pdf","source":{"id":"https://openalex.org/S4210198593","display_name":"Journal of Surgical Case Reports","issn_l":"2042-8812","issn":["2042-8812"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Surgical Case Reports","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/jscr/article-pdf/2026/11/rjag991/72931852/rjag991.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5160697667","display_name":"Norie Tojo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I40677808","display_name":"Kyoto Prefectural University of Medicine","ror":"https://ror.org/028vxwa22","country_code":"JP","type":"education","lineage":["https://openalex.org/I40677808","https://openalex.org/I4405285717"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Norie Tojo","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine , 465 Kajiicho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566 ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine , 465 Kajiicho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566 ,","institution_ids":["https://openalex.org/I40677808"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108269785","display_name":"Hisashi Kataoka","orcid":"https://orcid.org/0000-0002-7397-4960","observed_orcids":["https://orcid.org/0000-0002-7397-4960"]},"institutions":[{"id":"https://openalex.org/I40677808","display_name":"Kyoto Prefectural University of Medicine","ror":"https://ror.org/028vxwa22","country_code":"JP","type":"education","lineage":["https://openalex.org/I40677808","https://openalex.org/I4405285717"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Hisashi Kataoka","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine , 465 Kajiicho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566 ,"],"raw_orcid":"https://orcid.org/0000-0002-7397-4960","affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine , 465 Kajiicho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566 ,","institution_ids":["https://openalex.org/I40677808"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040927185","display_name":"Yuko Izumi","orcid":"https://orcid.org/0000-0001-9595-9502","observed_orcids":["https://orcid.org/0000-0001-9595-9502"]},"institutions":[{"id":"https://openalex.org/I40677808","display_name":"Kyoto Prefectural University of Medicine","ror":"https://ror.org/028vxwa22","country_code":"JP","type":"education","lineage":["https://openalex.org/I40677808","https://openalex.org/I4405285717"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yuko Izumi","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine , 465 Kajiicho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566 ,"],"raw_orcid":"https://orcid.org/0000-0001-9595-9502","affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine , 465 Kajiicho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566 ,","institution_ids":["https://openalex.org/I40677808"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083891011","display_name":"Yosuke Tarumi","orcid":"https://orcid.org/0000-0002-6058-594X","observed_orcids":["https://orcid.org/0000-0002-6058-594X"]},"institutions":[{"id":"https://openalex.org/I40677808","display_name":"Kyoto Prefectural University of Medicine","ror":"https://ror.org/028vxwa22","country_code":"JP","type":"education","lineage":["https://openalex.org/I40677808","https://openalex.org/I4405285717"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yosuke Tarumi","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine , 465 Kajiicho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566 ,"],"raw_orcid":"https://orcid.org/0000-0002-6058-594X","affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine , 465 Kajiicho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566 ,","institution_ids":["https://openalex.org/I40677808"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5085834699","display_name":"Taisuke Mori","orcid":"https://orcid.org/0000-0002-9792-4132","observed_orcids":["https://orcid.org/0000-0002-9792-4132"]},"institutions":[{"id":"https://openalex.org/I40677808","display_name":"Kyoto Prefectural University of Medicine","ror":"https://ror.org/028vxwa22","country_code":"JP","type":"education","lineage":["https://openalex.org/I40677808","https://openalex.org/I4405285717"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Taisuke Mori","raw_affiliation_strings":["Department of Obstetrics and Gynecology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine , 465 Kajiicho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566 ,"],"raw_orcid":"https://orcid.org/0000-0002-9792-4132","affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine , 465 Kajiicho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566 ,","institution_ids":["https://openalex.org/I40677808"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5108269785"],"corresponding_institution_ids":["https://openalex.org/I40677808"],"apc_list":{"value":1000,"currency":"USD","value_usd":1000},"apc_paid":{"value":1000,"currency":"USD","value_usd":1000},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.84230473,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"2026","issue":"11","first_page":"rjag991","last_page":"rjag991"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10935","display_name":"Endometriosis Research and Treatment","score":0.9628999829292297,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10935","display_name":"Endometriosis Research and Treatment","score":0.9628999829292297,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12992","display_name":"Metastasis and carcinoma case studies","score":0.027400000020861626,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10668","display_name":"Endometrial and Cervical Cancer Treatments","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2729","display_name":"Obstetrics and Gynecology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/intestinal-endometriosis","display_name":"intestinal endometriosis","score":0.9120000004768372},{"id":"https://openalex.org/keywords/malignant-transformation","display_name":"malignant transformation","score":0.7839999794960022},{"id":"https://openalex.org/keywords/differential-diagnosis","display_name":"differential diagnosis","score":0.8230000138282776},{"id":"https://openalex.org/keywords/mullerian-origin","display_name":"M\u00fcllerian origin","score":0.6850000023841858},{"id":"https://openalex.org/keywords/immunohistochemistry","display_name":"immunohistochemistry","score":0.7390000224113464},{"id":"https://openalex.org/keywords/estrogen-receptor","display_name":"estrogen receptor","score":0.7720000147819519},{"id":"https://openalex.org/keywords/pax8","display_name":"PAX8","score":0.7900000214576721},{"id":"https://openalex.org/keywords/cytokeratin-7","display_name":"CK7","score":0.9160000085830688},{"id":"https://openalex.org/keywords/cytokeratin-20","display_name":"CK20","score":0.875},{"id":"https://openalex.org/keywords/cdx2","display_name":"CDX2","score":0.7409999966621399},{"id":"https://openalex.org/keywords/uterine-invasion","display_name":"uterine invasion","score":0.7599999904632568},{"id":"https://openalex.org/keywords/lymph-node-metastasis","display_name":"lymph node metastasis","score":0.8140000104904175},{"id":"https://openalex.org/keywords/rectosigmoid-tumors","display_name":"rectosigmoid tumors","score":0.7559999823570251},{"id":"https://openalex.org/keywords/endometrioma","display_name":"endometrioma","score":0.8889999985694885}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8930000066757202},{"id":"https://openalex.org/C2779522080","wikidata":"https://www.wikidata.org/wiki/Q205764","display_name":"Endometriosis","level":2,"score":0.7742999792098999},{"id":"https://openalex.org/C2779012181","wikidata":"https://www.wikidata.org/wiki/Q2750567","display_name":"Cytokeratin","level":3,"score":0.6840999722480774},{"id":"https://openalex.org/C2781182431","wikidata":"https://www.wikidata.org/wiki/Q356033","display_name":"Adenocarcinoma","level":3,"score":0.5471000075340271},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.5242000222206116},{"id":"https://openalex.org/C31033888","wikidata":"https://www.wikidata.org/wiki/Q752076","display_name":"Malignant transformation","level":2,"score":0.47999998927116394},{"id":"https://openalex.org/C2777546739","wikidata":"https://www.wikidata.org/wiki/Q33525","display_name":"Carcinoma","level":2,"score":0.44920000433921814},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.44609999656677246},{"id":"https://openalex.org/C2780283643","wikidata":"https://www.wikidata.org/wiki/Q2110267","display_name":"Primary tumor","level":4,"score":0.44449999928474426},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.44020000100135803},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.4287000000476837},{"id":"https://openalex.org/C2775934546","wikidata":"https://www.wikidata.org/wiki/Q179991","display_name":"Biopsy","level":2,"score":0.421099990606308},{"id":"https://openalex.org/C2780849966","wikidata":"https://www.wikidata.org/wiki/Q170758","display_name":"Lymph node","level":2,"score":0.40939998626708984},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.3569999933242798},{"id":"https://openalex.org/C2781074409","wikidata":"https://www.wikidata.org/wiki/Q158716","display_name":"Rectum","level":2,"score":0.3377000093460083},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.33739998936653137},{"id":"https://openalex.org/C2780140570","wikidata":"https://www.wikidata.org/wiki/Q3545481","display_name":"Surgical oncology","level":2,"score":0.32710000872612},{"id":"https://openalex.org/C2777424391","wikidata":"https://www.wikidata.org/wiki/Q1163908","display_name":"Melena","level":2,"score":0.29840001463890076},{"id":"https://openalex.org/C146357865","wikidata":"https://www.wikidata.org/wiki/Q1123245","display_name":"Stage (stratigraphy)","level":2,"score":0.2912999987602234},{"id":"https://openalex.org/C2779720271","wikidata":"https://www.wikidata.org/wiki/Q179422","display_name":"Lymph","level":2,"score":0.27149999141693115},{"id":"https://openalex.org/C2781156865","wikidata":"https://www.wikidata.org/wiki/Q827023","display_name":"Lesion","level":2,"score":0.26930001378059387},{"id":"https://openalex.org/C189689871","wikidata":"https://www.wikidata.org/wiki/Q14864152","display_name":"Keratin 7","level":4,"score":0.2639999985694885},{"id":"https://openalex.org/C2776606343","wikidata":"https://www.wikidata.org/wiki/Q5376361","display_name":"Endometrial biopsy","level":3,"score":0.2630999982357025},{"id":"https://openalex.org/C2777164284","wikidata":"https://www.wikidata.org/wiki/Q277954","display_name":"Estrogen","level":2,"score":0.257999986410141},{"id":"https://openalex.org/C2909234372","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal adenocarcinoma","level":4,"score":0.25519999861717224},{"id":"https://openalex.org/C2779066055","wikidata":"https://www.wikidata.org/wiki/Q9612","display_name":"Uterus","level":2,"score":0.2533000111579895}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1093/jscr/rjag991","doi":"https://doi.org/10.1093/jscr/rjag991","is_oa":true,"landing_page_url":"https://doi.org/10.1093/jscr/rjag991","pdf_url":"https://academic.oup.com/jscr/article-pdf/2026/11/rjag991/72931852/rjag991.pdf","source":{"id":"https://openalex.org/S4210198593","display_name":"Journal of Surgical Case Reports","issn_l":"2042-8812","issn":["2042-8812"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Surgical Case Reports","raw_type":"journal-article"},{"id":"pmid:42984604","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42984604","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of surgical case reports","raw_type":"Case Reports"},{"id":"pmh:oai:pubmedcentral.nih.gov:13731195","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13731195/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Surg Case Rep","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/jscr/rjag991","doi":"https://doi.org/10.1093/jscr/rjag991","is_oa":true,"landing_page_url":"https://doi.org/10.1093/jscr/rjag991","pdf_url":"https://academic.oup.com/jscr/article-pdf/2026/11/rjag991/72931852/rjag991.pdf","source":{"id":"https://openalex.org/S4210198593","display_name":"Journal of Surgical Case Reports","issn_l":"2042-8812","issn":["2042-8812"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Surgical Case Reports","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9789000153541565}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7225247004.pdf","grobid_xml":"https://content.openalex.org/works/W7225247004.grobid-xml"},"referenced_works_count":4,"referenced_works":["https://openalex.org/W1578820787","https://openalex.org/W2772449900","https://openalex.org/W2773417330","https://openalex.org/W7134984123"],"related_works":["https://openalex.org/W185529935","https://openalex.org/W4387904143","https://openalex.org/W2319429911","https://openalex.org/W1995548422","https://openalex.org/W2035203837","https://openalex.org/W4284976926","https://openalex.org/W2039090171","https://openalex.org/W948743858","https://openalex.org/W7168090809","https://openalex.org/W4402077602"],"abstract_inverted_index":{"Malignant":[0],"transformation":[1,117],"of":[2,20,61,69,103,118,126,139],"intestinal":[3,45,119],"endometriosis":[4,22,46,53],"is":[5],"rare":[6],"and":[7,26,33,54,86,89,94,115,134],"may":[8],"closely":[9],"mimic":[10],"primary":[11,62],"colorectal":[12,63],"adenocarcinoma.":[13,64],"A":[14],"43-year-old":[15],"woman":[16],"with":[17,24,30,44],"a":[18,27,70,108,112],"history":[19],"ovarian":[21],"presented":[23],"melena":[25],"rectosigmoid":[28],"tumor":[29,106,128],"uterine":[31],"invasion":[32],"multiple":[34],"lymph":[35],"node":[36],"metastases.":[37],"Histopathological":[38],"examination":[39],"revealed":[40],"moderately":[41],"differentiated":[42],"adenocarcinoma":[43,77],"but":[47],"no":[48],"definitive":[49],"transition":[50],"between":[51],"the":[52,55,104,124,136],"carcinoma,":[56],"supporting":[57,111],"an":[58,76],"initial":[59],"diagnosis":[60],"Five":[65],"years":[66],"later,":[67],"biopsy":[68],"recurrent":[71],"vaginal":[72],"stump":[73],"lesion":[74],"showed":[75],"positive":[78],"for":[79,91],"estrogen":[80],"receptor,":[81],"paired":[82],"box":[83],"gene":[84],"8,":[85],"cytokeratin":[87,92],"7":[88],"negative":[90],"20":[93],"caudal-type":[95],"homeobox":[96],"transcription":[97],"factor":[98],"2.":[99],"Retrospective":[100],"immunohistochemical":[101],"evaluation":[102],"original":[105],"demonstrated":[107],"similar":[109],"phenotype,":[110],"M\u00fcllerian":[113],"origin":[114,129],"malignant":[116],"endometriosis.":[120],"This":[121],"case":[122],"illustrates":[123],"difficulty":[125],"determining":[127],"based":[130],"on":[131],"morphology":[132],"alone":[133],"highlights":[135],"diagnostic":[137],"value":[138],"immunohistochemistry.":[140]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2026-11-05T00:00:00"}