{"id":"https://openalex.org/W7225237186","doi":"https://doi.org/10.1186/s12903-026-10293-7","title":"Surgically assisted versus nonsurgical skeletally anchored maxillary expansion: a retrospective comparative study of dentoalveolar effects using 3D digital models","display_name":"Surgically assisted versus nonsurgical skeletally anchored maxillary expansion: a retrospective comparative study of dentoalveolar effects using 3D digital models","publication_year":2026,"publication_date":"2026-11-04","ids":{"openalex":"https://openalex.org/W7225237186","doi":"https://doi.org/10.1186/s12903-026-10293-7"},"language":"en","primary_location":{"id":"doi:10.1186/s12903-026-10293-7","doi":"https://doi.org/10.1186/s12903-026-10293-7","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12903-026-10293-7","pdf_url":null,"source":{"id":"https://openalex.org/S60760007","display_name":"BMC Oral Health","issn_l":"1472-6831","issn":["1472-6831"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","medline","norway-2","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Oral Health","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1186/s12903-026-10293-7","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5160633902","display_name":"Krist\u00f3f Andr\u00e1s Vass","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I101202996","display_name":"Semmelweis University","ror":"https://ror.org/01g9ty582","country_code":"HU","type":"education","lineage":["https://openalex.org/I101202996"]}],"countries":["HU"],"is_corresponding":true,"raw_author_name":"Krist\u00f3f Andr\u00e1s Vass","raw_affiliation_strings":["Department of Paediatric Dentistry and Orthodontics, Semmelweis University, Budapest, Hungary","Faculty of Dentistry, Semmelweis University, Szentkir\u00e1lyi utca 47, Budapest, 1088, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Paediatric Dentistry and Orthodontics, Semmelweis University, Budapest, Hungary","institution_ids":["https://openalex.org/I101202996"]},{"raw_affiliation_string":"Faculty of Dentistry, Semmelweis University, Szentkir\u00e1lyi utca 47, Budapest, 1088, Hungary","institution_ids":["https://openalex.org/I101202996"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114323778","display_name":"Gergely L\u0151rincz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I101202996","display_name":"Semmelweis University","ror":"https://ror.org/01g9ty582","country_code":"HU","type":"education","lineage":["https://openalex.org/I101202996"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"Gergely L\u0151rincz","raw_affiliation_strings":["Department of Paediatric Dentistry and Orthodontics, Semmelweis University, Budapest, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Paediatric Dentistry and Orthodontics, Semmelweis University, Budapest, Hungary","institution_ids":["https://openalex.org/I101202996"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107263303","display_name":"Anna Tfirst","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I101202996","display_name":"Semmelweis University","ror":"https://ror.org/01g9ty582","country_code":"HU","type":"education","lineage":["https://openalex.org/I101202996"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"Anna Tfirst","raw_affiliation_strings":["Department of Paediatric Dentistry and Orthodontics, Semmelweis University, Budapest, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Paediatric Dentistry and Orthodontics, Semmelweis University, Budapest, Hungary","institution_ids":["https://openalex.org/I101202996"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084680119","display_name":"Patrik Kreuter","orcid":"https://orcid.org/0000-0002-4587-4284","observed_orcids":["https://orcid.org/0000-0002-4587-4284"]},"institutions":[{"id":"https://openalex.org/I101202996","display_name":"Semmelweis University","ror":"https://ror.org/01g9ty582","country_code":"HU","type":"education","lineage":["https://openalex.org/I101202996"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"Patrik Kreuter","raw_affiliation_strings":["Department of Paediatric Dentistry and Orthodontics, Semmelweis University, Budapest, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Paediatric Dentistry and Orthodontics, Semmelweis University, Budapest, Hungary","institution_ids":["https://openalex.org/I101202996"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160637819","display_name":"Domonkos M\u00e1t\u00e9 Vass","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I29770179","display_name":"Budapest University of Technology and Economics","ror":"https://ror.org/02w42ss30","country_code":"HU","type":"education","lineage":["https://openalex.org/I29770179"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"Domonkos M\u00e1t\u00e9 Vass","raw_affiliation_strings":["Faculty of Transportation Engineering and Vehicle Engineering, Budapest University of Technology and Economics, Budapest, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Transportation Engineering and Vehicle Engineering, Budapest University of Technology and Economics, Budapest, Hungary","institution_ids":["https://openalex.org/I29770179"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065352247","display_name":"Kyoichi Haba","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I101202996","display_name":"Semmelweis University","ror":"https://ror.org/01g9ty582","country_code":"HU","type":"education","lineage":["https://openalex.org/I101202996"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"Kata S\u00e1ra Haba","raw_affiliation_strings":["Department of Prosthodontics, Semmelweis University, Budapest, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Prosthodontics, Semmelweis University, Budapest, Hungary","institution_ids":["https://openalex.org/I101202996"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037194168","display_name":"Tam\u00e1s Haba","orcid":"https://orcid.org/0000-0001-7183-6014","observed_orcids":["https://orcid.org/0000-0001-7183-6014"]},"institutions":[{"id":"https://openalex.org/I29770179","display_name":"Budapest University of Technology and Economics","ror":"https://ror.org/02w42ss30","country_code":"HU","type":"education","lineage":["https://openalex.org/I29770179"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"Tam\u00e1s Haba","raw_affiliation_strings":["Department of Mechatronics, Optics and Mechanical Engineering Informatics, Budapest University of Technology and Economics, Budapest, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Mechatronics, Optics and Mechanical Engineering Informatics, Budapest University of Technology and Economics, Budapest, Hungary","institution_ids":["https://openalex.org/I29770179"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107263302","display_name":"Zsuzsanna Stef\u00e1nia Rad\u00f3","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1850255","display_name":"University of Basel","ror":"https://ror.org/02s6k3f65","country_code":"CH","type":"education","lineage":["https://openalex.org/I1850255"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Zsuzsanna Stef\u00e1nia Rad\u00f3","raw_affiliation_strings":["Department of Paediatric Oral Health and Orthodontics, University Centre for Dental Medicine Basel, Mattenstrasse 40, Basel, 4058, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Paediatric Oral Health and Orthodontics, University Centre for Dental Medicine Basel, Mattenstrasse 40, Basel, 4058, Switzerland","institution_ids":["https://openalex.org/I1850255"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160686473","display_name":"P\u00e9ter Lillik","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I101202996","display_name":"Semmelweis University","ror":"https://ror.org/01g9ty582","country_code":"HU","type":"education","lineage":["https://openalex.org/I101202996"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"P\u00e9ter Lillik","raw_affiliation_strings":["Department of Oro-Maxillofacial Surgery and Stomatology, Semmelweis University, Budapest, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oro-Maxillofacial Surgery and Stomatology, Semmelweis University, Budapest, Hungary","institution_ids":["https://openalex.org/I101202996"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051777655","display_name":"Tam\u00e1s W\u00fcrsching","orcid":"https://orcid.org/0000-0003-1939-0216","observed_orcids":["https://orcid.org/0000-0003-1939-0216"]},"institutions":[{"id":"https://openalex.org/I101202996","display_name":"Semmelweis University","ror":"https://ror.org/01g9ty582","country_code":"HU","type":"education","lineage":["https://openalex.org/I101202996"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"Tam\u00e1s W\u00fcrsching","raw_affiliation_strings":["Department of Oro-Maxillofacial Surgery and Stomatology, Semmelweis University, Budapest, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oro-Maxillofacial Surgery and Stomatology, Semmelweis University, Budapest, Hungary","institution_ids":["https://openalex.org/I101202996"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003051055","display_name":"S\u00e1ndor Bogd\u00e1n","orcid":"https://orcid.org/0009-0008-9022-9824","observed_orcids":["https://orcid.org/0009-0008-9022-9824","https://orcid.org/0000-0003-2890-8486"]},"institutions":[{"id":"https://openalex.org/I101202996","display_name":"Semmelweis University","ror":"https://ror.org/01g9ty582","country_code":"HU","type":"education","lineage":["https://openalex.org/I101202996"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"S\u00e1ndor Bogd\u00e1n","raw_affiliation_strings":["Department of Oro-Maxillofacial Surgery and Stomatology, Semmelweis University, Budapest, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oro-Maxillofacial Surgery and Stomatology, Semmelweis University, Budapest, Hungary","institution_ids":["https://openalex.org/I101202996"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003726052","display_name":"No\u00e9mi Katinka R\u00f3zsa","orcid":"https://orcid.org/0000-0002-8510-7047","observed_orcids":["https://orcid.org/0000-0002-8510-7047"]},"institutions":[{"id":"https://openalex.org/I101202996","display_name":"Semmelweis University","ror":"https://ror.org/01g9ty582","country_code":"HU","type":"education","lineage":["https://openalex.org/I101202996"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"No\u00e9mi Katinka R\u00f3zsa","raw_affiliation_strings":["Department of Paediatric Dentistry and Orthodontics, Semmelweis University, Budapest, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Paediatric Dentistry and Orthodontics, Semmelweis University, Budapest, Hungary","institution_ids":["https://openalex.org/I101202996"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5112693737","display_name":"B\u00e1lint Nemes","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I101202996","display_name":"Semmelweis University","ror":"https://ror.org/01g9ty582","country_code":"HU","type":"education","lineage":["https://openalex.org/I101202996"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"B\u00e1lint Nemes","raw_affiliation_strings":["Department of Paediatric Dentistry and Orthodontics, Semmelweis University, Budapest, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Paediatric Dentistry and Orthodontics, Semmelweis University, Budapest, Hungary","institution_ids":["https://openalex.org/I101202996"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5160633902"],"corresponding_institution_ids":["https://openalex.org/I101202996"],"apc_list":{"value":3190,"currency":"USD","value_usd":3190},"apc_paid":{"value":3190,"currency":"USD","value_usd":3190},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.8906747,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10356","display_name":"Orthodontics and Dentofacial Orthopedics","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/3505","display_name":"Orthodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10356","display_name":"Orthodontics and Dentofacial Orthopedics","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/3505","display_name":"Orthodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11679","display_name":"Craniofacial Disorders and Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11562","display_name":"Facial Trauma and Fracture Management","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/adult-orthodontics","display_name":"adult orthodontics","score":0.6359999775886536},{"id":"https://openalex.org/keywords/3d-digital-models","display_name":"3D digital models","score":0.7129999995231628}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9434999823570251},{"id":"https://openalex.org/C2778636310","wikidata":"https://www.wikidata.org/wiki/Q504033","display_name":"Oral and maxillofacial surgery","level":2,"score":0.6442999839782715},{"id":"https://openalex.org/C202271784","wikidata":"https://www.wikidata.org/wiki/Q189218","display_name":"Molar","level":2,"score":0.6172000169754028},{"id":"https://openalex.org/C2777982226","wikidata":"https://www.wikidata.org/wiki/Q143480","display_name":"Dental arch","level":2,"score":0.5990999937057495},{"id":"https://openalex.org/C2780641865","wikidata":"https://www.wikidata.org/wiki/Q839483","display_name":"Premolar","level":3,"score":0.5796999931335449},{"id":"https://openalex.org/C195735259","wikidata":"https://www.wikidata.org/wiki/Q16963239","display_name":"Buccal administration","level":2,"score":0.5702999830245972},{"id":"https://openalex.org/C199343813","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Dentistry","level":1,"score":0.5444999933242798},{"id":"https://openalex.org/C29694066","wikidata":"https://www.wikidata.org/wiki/Q118301","display_name":"Orthodontics","level":1,"score":0.5113999843597412},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.38920000195503235},{"id":"https://openalex.org/C122246415","wikidata":"https://www.wikidata.org/wiki/Q350956","display_name":"Maxilla","level":2,"score":0.3050000071525574},{"id":"https://openalex.org/C2777081826","wikidata":"https://www.wikidata.org/wiki/Q2418904","display_name":"Cephalometry","level":2,"score":0.2962000072002411},{"id":"https://openalex.org/C2780950006","wikidata":"https://www.wikidata.org/wiki/Q2562599","display_name":"Maxillary canine","level":2,"score":0.2849000096321106},{"id":"https://openalex.org/C3018023364","wikidata":"https://www.wikidata.org/wiki/Q425265","display_name":"Significant difference","level":2,"score":0.2824999988079071},{"id":"https://openalex.org/C11312509","wikidata":"https://www.wikidata.org/wiki/Q12277","display_name":"Arch","level":2,"score":0.2766000032424927},{"id":"https://openalex.org/C2780109367","wikidata":"https://www.wikidata.org/wiki/Q1320428","display_name":"Malocclusion","level":2,"score":0.27469998598098755}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1186/s12903-026-10293-7","doi":"https://doi.org/10.1186/s12903-026-10293-7","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12903-026-10293-7","pdf_url":null,"source":{"id":"https://openalex.org/S60760007","display_name":"BMC Oral Health","issn_l":"1472-6831","issn":["1472-6831"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","medline","norway-2","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Oral Health","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1186/s12903-026-10293-7","doi":"https://doi.org/10.1186/s12903-026-10293-7","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s12903-026-10293-7","pdf_url":null,"source":{"id":"https://openalex.org/S60760007","display_name":"BMC Oral Health","issn_l":"1472-6831","issn":["1472-6831"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","medline","norway-2","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Oral Health","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9391000270843506,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W6939839901","https://openalex.org/W3165677081","https://openalex.org/W4412689148","https://openalex.org/W6957855167","https://openalex.org/W1975896215","https://openalex.org/W3005566870","https://openalex.org/W2259036268","https://openalex.org/W7118093171","https://openalex.org/W4414561964","https://openalex.org/W4381186515"],"abstract_inverted_index":{"Abstract":[0],"Background":[1],"Skeletally":[2],"anchored":[3,59,67],"maxillary":[4,42,60,68],"expansion":[5,28,43,61,157,168,176],"may":[6],"be":[7],"performed":[8],"with":[9,55,64,114,159],"or":[10,142,178],"without":[11],"surgical":[12,20],"assistance":[13,21],"in":[14,86,125,174,183],"adults.":[15],"However,":[16],"the":[17,23,45,82,87,90,97,105],"effect":[18],"of":[19,26,96],"on":[22,206],"geometric":[24],"pattern":[25,158],"arch":[27,84,175],"and":[29,40,62,71,100,110,166,191],"dentoalveolar":[30],"side":[31,181],"effects":[32,182],"remains":[33],"uncertain.":[34],"This":[35],"study":[36],"compared":[37],"surgically":[38,56],"assisted":[39,57,165],"nonsurgical":[41,65,167],"using":[44],"MICRO-4":[46],"appliance.":[47],"Methods":[48],"90":[49],"patients":[50],"were":[51,75,123],"included,":[52],"45":[53,63],"treated":[54],"skeletally":[58,66],"expansion.":[69],"Pre-":[70],"post-treatment":[72],"intraoral":[73],"scans":[74],"digitally":[76],"analysed.":[77],"The":[78],"primary":[79],"outcome":[80,92],"was":[81,93],"V-shaped":[83],"opening":[85],"horizontal":[88],"plane;":[89],"secondary":[91],"buccal":[94,134,144,161],"rolling":[95,135,145],"upper":[98],"premolars":[99],"molars.":[101],"Statistical":[102],"analyses":[103],"included":[104],"Shapiro\u2013Wilk":[106],"test,":[107,113],"Welch\u2019s":[108],"t-test,":[109],"Mann\u2013Whitney":[111],"U":[112,137,147],"$$\\:\\alpha\\:=0.05$$":[115],".":[116],"Results":[117],"No":[118],"statistically":[119,171],"significant":[120,172],"between-group":[121],"differences":[122],"observed":[124],"V-value":[126],"(Welch\u2019s":[127],"t":[128],"-test,":[129,138,148],"p":[130,139,149],"=":[131,140,150],"0.785),":[132],"premolar":[133],"(Mann\u2013Whitney":[136,146],"0.815),":[141],"molar":[143],"0.145).":[151],"Both":[152],"groups":[153],"showed":[154,169],"a":[155],"fan-shaped":[156],"minimal":[160],"rolling.":[162],"Conclusions":[163],"Surgically":[164],"no":[170],"difference":[173],"geometry":[177],"measured":[179],"dental":[180],"this":[184],"population.":[185],"Further":[186],"investigations":[187],"including":[188],"post-expansion":[189],"treatment":[190],"long-term":[192],"follow-up":[193],"are":[194],"needed":[195],"to":[196],"validate":[197],"these":[198],"findings.":[199],"Trial":[200],"registration":[201],"clinicaltrials.gov,":[202],"NCT07383376,":[203],"Retrospectively":[204],"registered":[205],"26":[207],"January":[208],"2026.":[209]},"counts_by_year":[],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2026-11-05T00:00:00"}