{"id":"https://openalex.org/W7225235231","doi":"https://doi.org/10.1186/s13244-026-02462-7","title":"Feasibility of one-stop multi-energy dynamic photon-counting perfusion CT for resectable HCC evaluation: lesion detection and histopathological correlations","display_name":"Feasibility of one-stop multi-energy dynamic photon-counting perfusion CT for resectable HCC evaluation: lesion detection and histopathological correlations","publication_year":2026,"publication_date":"2026-11-04","ids":{"openalex":"https://openalex.org/W7225235231","doi":"https://doi.org/10.1186/s13244-026-02462-7","pmid":"https://pubmed.ncbi.nlm.nih.gov/42980729"},"language":"en","primary_location":{"id":"doi:10.1186/s13244-026-02462-7","doi":"https://doi.org/10.1186/s13244-026-02462-7","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13244-026-02462-7","pdf_url":"https://link.springer.com/content/pdf/10.1186/s13244-026-02462-7.pdf","source":{"id":"https://openalex.org/S44632665","display_name":"Insights into Imaging","issn_l":"1869-4101","issn":["1869-4101"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Insights into Imaging","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://link.springer.com/content/pdf/10.1186/s13244-026-02462-7.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102361409","display_name":"Huimin Lin","orcid":"https://orcid.org/0009-0007-8181-5277","observed_orcids":["https://orcid.org/0009-0007-8181-5277"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2801556517","display_name":"Ruijin Hospital","ror":"https://ror.org/01hv94n30","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801556517"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Huimin Lin","raw_affiliation_strings":["Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. lhm12362@rjh.com.cn","Faculty of Medical Imaging Technology, College of Health Science and Technology, Shanghai Jiao Tong University School of Medicine, Shanghai, China. lhm12362@rjh.com.cn"],"raw_orcid":"https://orcid.org/0009-0007-8181-5277","affiliations":[{"raw_affiliation_string":"Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. lhm12362@rjh.com.cn","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2801556517"]},{"raw_affiliation_string":"Faculty of Medical Imaging Technology, College of Health Science and Technology, Shanghai Jiao Tong University School of Medicine, Shanghai, China. lhm12362@rjh.com.cn","institution_ids":["https://openalex.org/I183067930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000149090","display_name":"Jiahao Zhou","orcid":"https://orcid.org/0000-0003-0790-5729","observed_orcids":["https://orcid.org/0000-0003-0790-5729"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2801556517","display_name":"Ruijin Hospital","ror":"https://ror.org/01hv94n30","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801556517"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiahao Zhou","raw_affiliation_strings":["Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2801556517"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041146217","display_name":"Rong Deng","orcid":"https://orcid.org/0000-0003-3724-0326","observed_orcids":["https://orcid.org/0000-0003-3724-0326"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2801556517","display_name":"Ruijin Hospital","ror":"https://ror.org/01hv94n30","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801556517"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Rong Deng","raw_affiliation_strings":["Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2801556517"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100314345","display_name":"Zhihan Xu","orcid":"https://orcid.org/0009-0008-9920-8632","observed_orcids":["https://orcid.org/0009-0008-9920-8632","https://orcid.org/0009-0000-6974-7055"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zhihan Xu","raw_affiliation_strings":["CT Collaboration, Siemens Healthineers, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CT Collaboration, Siemens Healthineers, Shanghai, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5144383086","display_name":"Yuchen Yang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2801556517","display_name":"Ruijin Hospital","ror":"https://ror.org/01hv94n30","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801556517"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuchen Yang","raw_affiliation_strings":["Department of General Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of General Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2801556517"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5123826400","display_name":"Yongjun Chen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2801556517","display_name":"Ruijin Hospital","ror":"https://ror.org/01hv94n30","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801556517"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yongjun Chen","raw_affiliation_strings":["Department of General Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of General Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2801556517"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113117612","display_name":"Huanhuan Chong","orcid":"https://orcid.org/0000-0003-4347-7602","observed_orcids":["https://orcid.org/0000-0003-4347-7602"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2801556517","display_name":"Ruijin Hospital","ror":"https://ror.org/01hv94n30","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801556517"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Huanhuan Chong","raw_affiliation_strings":["Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China","Faculty of Medical Imaging Technology, College of Health Science and Technology, Shanghai Jiao Tong University School of Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2801556517"]},{"raw_affiliation_string":"Faculty of Medical Imaging Technology, College of Health Science and Technology, Shanghai Jiao Tong University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I183067930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070523830","display_name":"Miao Ruan","orcid":"https://orcid.org/0000-0001-9907-2482","observed_orcids":["https://orcid.org/0000-0001-9907-2482"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2801556517","display_name":"Ruijin Hospital","ror":"https://ror.org/01hv94n30","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801556517"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Miao Ruan","raw_affiliation_strings":["Department of Pathology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2801556517"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101513620","display_name":"Chunxue Yang","orcid":"https://orcid.org/0000-0002-2918-7505","observed_orcids":["https://orcid.org/0000-0002-2918-7505"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2801556517","display_name":"Ruijin Hospital","ror":"https://ror.org/01hv94n30","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801556517"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chunxue Yang","raw_affiliation_strings":["Department of Pathology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2801556517"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160703817","display_name":"Haipeng Dong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2801556517","display_name":"Ruijin Hospital","ror":"https://ror.org/01hv94n30","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801556517"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Haipeng Dong","raw_affiliation_strings":["Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2801556517"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5135135951","display_name":"Rui Chang","orcid":"https://orcid.org/0009-0006-6852-1007","observed_orcids":["https://orcid.org/0009-0006-6852-1007"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2801556517","display_name":"Ruijin Hospital","ror":"https://ror.org/01hv94n30","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801556517"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Rui Chang","raw_affiliation_strings":["Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2801556517"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160717857","display_name":"Ruokun Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2801556517","display_name":"Ruijin Hospital","ror":"https://ror.org/01hv94n30","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801556517"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ruokun Li","raw_affiliation_strings":["Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China","Faculty of Medical Imaging Technology, College of Health Science and Technology, Shanghai Jiao Tong University School of Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2801556517"]},{"raw_affiliation_string":"Faculty of Medical Imaging Technology, College of Health Science and Technology, Shanghai Jiao Tong University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I183067930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5150828049","display_name":"Weixia Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2801556517","display_name":"Ruijin Hospital","ror":"https://ror.org/01hv94n30","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801556517"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Weixia Li","raw_affiliation_strings":["Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. lwx11721@rjh.com.cn"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. lwx11721@rjh.com.cn","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2801556517"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101402484","display_name":"Fuhua Yan","orcid":"https://orcid.org/0000-0002-8969-703X","observed_orcids":["https://orcid.org/0000-0002-8969-703X","https://orcid.org/0000-0002-5910-1506"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2801556517","display_name":"Ruijin Hospital","ror":"https://ror.org/01hv94n30","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801556517"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Fuhua Yan","raw_affiliation_strings":["Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. yfh11655@rjh.com.cn","Faculty of Medical Imaging Technology, College of Health Science and Technology, Shanghai Jiao Tong University School of Medicine, Shanghai, China. yfh11655@rjh.com.cn"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. yfh11655@rjh.com.cn","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2801556517"]},{"raw_affiliation_string":"Faculty of Medical Imaging Technology, College of Health Science and Technology, Shanghai Jiao Tong University School of Medicine, Shanghai, China. yfh11655@rjh.com.cn","institution_ids":["https://openalex.org/I183067930"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5101402484","https://openalex.org/A5102361409","https://openalex.org/A5150828049"],"corresponding_institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2801556517"],"apc_list":{"value":3290,"currency":"USD","value_usd":3290},"apc_paid":{"value":3290,"currency":"USD","value_usd":3290},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.73699478,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"17","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12386","display_name":"Advanced X-ray and CT Imaging","score":0.9634000062942505,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12386","display_name":"Advanced X-ray and CT Imaging","score":0.9634000062942505,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10073","display_name":"Hepatocellular Carcinoma Treatment and Prognosis","score":0.017100000753998756,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.014299999922513962,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hepatocellular-carcinoma","display_name":"hepatocellular carcinoma","score":0.9769999980926514},{"id":"https://openalex.org/keywords/photon-counting-ct","display_name":"photon-counting CT","score":0.8640000224113464},{"id":"https://openalex.org/keywords/multi-energy-ct","display_name":"multi-energy CT","score":0.8370000123977661},{"id":"https://openalex.org/keywords/energy-integrating-detector-ct","display_name":"energy-integrating detector CT","score":0.8180000185966492},{"id":"https://openalex.org/keywords/microvascular-invasion","display_name":"microvascular invasion","score":0.753000020980835},{"id":"https://openalex.org/keywords/histological-grade","display_name":"histological grade","score":0.8410000205039978},{"id":"https://openalex.org/keywords/hepatic-perfusion-index","display_name":"hepatic perfusion index","score":0.8090000152587891},{"id":"https://openalex.org/keywords/low-dose-computed-tomography","display_name":"low-dose CT","score":0.5540000200271606},{"id":"https://openalex.org/keywords/lesion-detection","display_name":"lesion detection","score":0.652999997138977},{"id":"https://openalex.org/keywords/histopathological-correlation","display_name":"histopathological correlation","score":0.7760000228881836},{"id":"https://openalex.org/keywords/radiation-dose","display_name":"radiation dose","score":0.5429999828338623}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9077000021934509},{"id":"https://openalex.org/C2778019345","wikidata":"https://www.wikidata.org/wiki/Q1148337","display_name":"Hepatocellular carcinoma","level":2,"score":0.7427999973297119},{"id":"https://openalex.org/C146957229","wikidata":"https://www.wikidata.org/wiki/Q1266915","display_name":"Perfusion","level":2,"score":0.730400025844574},{"id":"https://openalex.org/C2779889316","wikidata":"https://www.wikidata.org/wiki/Q642836","display_name":"Neuroradiology","level":3,"score":0.6517000198364258},{"id":"https://openalex.org/C2781156865","wikidata":"https://www.wikidata.org/wiki/Q827023","display_name":"Lesion","level":2,"score":0.6284999847412109},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.588699996471405},{"id":"https://openalex.org/C158846371","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Blood flow","level":2,"score":0.5605999827384949},{"id":"https://openalex.org/C135691158","wikidata":"https://www.wikidata.org/wiki/Q7168308","display_name":"Perfusion scanning","level":3,"score":0.4742000102996826},{"id":"https://openalex.org/C513090587","wikidata":"https://www.wikidata.org/wiki/Q426449","display_name":"Interventional radiology","level":2,"score":0.446399986743927},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.438400000333786},{"id":"https://openalex.org/C178853913","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Hemodynamics","level":2,"score":0.38679999113082886},{"id":"https://openalex.org/C2777546739","wikidata":"https://www.wikidata.org/wiki/Q33525","display_name":"Carcinoma","level":2,"score":0.3377000093460083},{"id":"https://openalex.org/C2779314089","wikidata":"https://www.wikidata.org/wiki/Q18026830","display_name":"HCCS","level":3,"score":0.3093999922275543},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3091000020503998},{"id":"https://openalex.org/C2779399171","wikidata":"https://www.wikidata.org/wiki/Q1483951","display_name":"Malignancy","level":2,"score":0.30090001225471497},{"id":"https://openalex.org/C37557685","wikidata":"https://www.wikidata.org/wiki/Q1896673","display_name":"Blood volume","level":2,"score":0.29429998993873596},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.29100000858306885},{"id":"https://openalex.org/C2775934546","wikidata":"https://www.wikidata.org/wiki/Q179991","display_name":"Biopsy","level":2,"score":0.28220000863075256},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.2793999910354614},{"id":"https://openalex.org/C55020928","wikidata":"https://www.wikidata.org/wiki/Q3813865","display_name":"Image quality","level":3,"score":0.25200000405311584}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1186/s13244-026-02462-7","doi":"https://doi.org/10.1186/s13244-026-02462-7","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13244-026-02462-7","pdf_url":"https://link.springer.com/content/pdf/10.1186/s13244-026-02462-7.pdf","source":{"id":"https://openalex.org/S44632665","display_name":"Insights into Imaging","issn_l":"1869-4101","issn":["1869-4101"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Insights into Imaging","raw_type":"journal-article"},{"id":"pmid:42980729","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42980729","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Insights into imaging","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1186/s13244-026-02462-7","doi":"https://doi.org/10.1186/s13244-026-02462-7","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13244-026-02462-7","pdf_url":"https://link.springer.com/content/pdf/10.1186/s13244-026-02462-7.pdf","source":{"id":"https://openalex.org/S44632665","display_name":"Insights into Imaging","issn_l":"1869-4101","issn":["1869-4101"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Insights into Imaging","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7225235231.pdf","grobid_xml":"https://content.openalex.org/works/W7225235231.grobid-xml"},"referenced_works_count":30,"referenced_works":["https://openalex.org/W1597042664","https://openalex.org/W1963656682","https://openalex.org/W1964829819","https://openalex.org/W1966218436","https://openalex.org/W2046827133","https://openalex.org/W2075808231","https://openalex.org/W2110510461","https://openalex.org/W2127503402","https://openalex.org/W2130557824","https://openalex.org/W2249091407","https://openalex.org/W2313003784","https://openalex.org/W2345469503","https://openalex.org/W2522251985","https://openalex.org/W2598959067","https://openalex.org/W2889741596","https://openalex.org/W2901343067","https://openalex.org/W2920811896","https://openalex.org/W3010646759","https://openalex.org/W3125871892","https://openalex.org/W3136423632","https://openalex.org/W4210490892","https://openalex.org/W4210774372","https://openalex.org/W4224300385","https://openalex.org/W4242769447","https://openalex.org/W4297785682","https://openalex.org/W4362640431","https://openalex.org/W4398171978","https://openalex.org/W4406367058","https://openalex.org/W4408332597","https://openalex.org/W4411729219"],"related_works":["https://openalex.org/W3134196331","https://openalex.org/W2017804627","https://openalex.org/W7023705630","https://openalex.org/W2075808231","https://openalex.org/W2324866510","https://openalex.org/W4223906049","https://openalex.org/W3153836955","https://openalex.org/W2118356620","https://openalex.org/W4404671958","https://openalex.org/W2362982438"],"abstract_inverted_index":{"Abstract":[0],"Objectives":[1],"To":[2],"assess":[3],"the":[4,122,130,343],"feasibility":[5],"of":[6,64,190,271,297,345],"one-stop":[7],"multi-energy":[8,317],"dynamic":[9,272,289,318],"volume":[10,273],"perfusion":[11,75,163,182,246,274,291,304,320],"photon-counting":[12,290,319],"CT":[13,57,275,292,321],"(VP-PCCT)":[14],"for":[15,62,142,215,276],"hepatocellular":[16],"carcinoma":[17],"(HCC)":[18],"evaluation,":[19],"including":[20],"lesion":[21,68],"detection":[22,150],"and":[23,28,46,67,92,96,125,144,168,186,206,225,245,263,311,325,348],"correlations":[24],"with":[25,38,49,79,116,127,134,146,232,253,260,303,337],"histopathology.":[26],"Materials":[27],"methods":[29],"From":[30],"July":[31],"2024":[32],"to":[33,101],"June":[34],"2025,":[35],"407":[36],"participants":[37,107],"suspected":[39],"malignant":[40],"liver":[41,181],"lesions":[42],"prospectively":[43],"underwent":[44],"VP-PCCT,":[45],"177":[47],"patients":[48],"pathology-confirmed":[50,117],"HCC":[51,118,143,279,298,310,335],"who":[52],"received":[53],"three-phase":[54],"energy-integrating":[55],"detector":[56],"(EID-CT)":[58],"were":[59,77,83,119,211,230],"retrospectively":[60],"enrolled":[61],"comparisons":[63],"image":[65,140],"quality":[66,141],"detectability.":[69],"Single-phase":[70],"images":[71],"reconstructed":[72],"from":[73],"VP-PCCT":[74,123,137,241],"datasets":[76],"compared":[78],"EID-CT.":[80],"Perfusion":[81],"parameters":[82,305],"analyzed":[84],"between":[85],"groups":[86],"stratified":[87],"separately":[88],"by":[89],"histological":[90,261,346],"grade":[91,262,347],"microvascular":[93],"invasion":[94],"(MVI),":[95],"logistic":[97],"regression":[98],"was":[99],"employed":[100],"identify":[102],"independent":[103,212],"indicators.":[104],"Results":[105],"Ninety-two":[106],"[median":[108],"age,":[109],"62":[110],"years":[111],"(IQR,":[112],"53\u201369);":[113],"76":[114],"males]":[115],"included":[120],"in":[121,129,248,328],"group":[124],"matched":[126],"92":[128],"EID-CT":[131],"group.":[132],"Compared":[133],"EID-CT,":[135],"40-keV":[136],"provided":[138,293],"comparable":[139],"vessels":[145],"a":[147,153,249,300,329],"similar":[148],"tumor":[149,161,166,179,184,201,222],"rate":[151],"but":[152],"lower":[154,178],"radiation":[155],"dose.":[156],"Poorly-differentiated":[157],"HCCs":[158,176],"showed":[159],"higher":[160],"hepatic":[162],"index":[164],"(HPI":[165],")":[167,185,195],"peritumoral":[169,191],"blood":[170,188],"flow":[171,189],"(BF":[172,193],"peritumor":[173,208],");":[174],"MVI-positive":[175],"exhibited":[177],"arterial":[180],"(ALP":[183],"normalized":[187],"region":[192],"norm_peritumor":[194,227],"(all":[196,235],"p":[197,236],"<":[198,237],"0.05).":[199,238],"HPI":[200],"[odds":[202],"ratio":[203],"(OR):":[204],"1.06]":[205],"BF":[207,226],"(OR:":[209,223,228],"1.04)":[210],"risk":[213],"factors":[214],"poorly":[216,308],"differentiated":[217,309],"HCC,":[218],"whereas":[219],"decreased":[220],"ALP":[221],"0.97)":[224],"0.25)":[229],"associated":[231,259],"MVI":[233,264],"positivity":[234],"Conclusions":[239],"One-stop":[240,316],"delivers":[242],"high-quality":[243,294,323],"morphologic":[244,295,324],"evaluation":[247,336],"single":[250,330],"low-dose":[251,331],"scan,":[252,332],"hemodynamic":[254,338],"profiles":[255],"that":[256,340],"may":[257,341],"be":[258],"status.":[265],"Key":[266],"Points":[267],"Question":[268],"Clinical":[269],"use":[270],"comprehensively":[277],"evaluating":[278],"without":[280],"additional":[281],"multiphase":[282],"contrast-enhanced":[283],"imaging":[284,296],"remains":[285],"limited.":[286],"Findings":[287],"Multi-energy":[288],"at":[299],"low":[301],"dose,":[302],"independently":[306],"indicating":[307],"MVI.":[312,349],"Critical":[313],"relevance":[314],"statement":[315],"enables":[322],"functional":[326],"assessment":[327,344],"providing":[333],"comprehensive":[334],"profiling":[339],"support":[342]},"counts_by_year":[],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2026-11-05T00:00:00"}