{"id":"https://openalex.org/W7225218954","doi":null,"title":"Comparative HPLC Fingerprinting and Cytotoxic Evaluation of Ethanol and Acetone Extracts of Mother and Finger Rhizomes of Curcuma longa L.","display_name":"Comparative HPLC Fingerprinting and Cytotoxic Evaluation of Ethanol and Acetone Extracts of Mother and Finger Rhizomes of Curcuma longa L.","publication_year":2026,"publication_date":"2026-11-02","ids":{"openalex":"https://openalex.org/W7225218954"},"language":"en","primary_location":{"id":"pmh:oai:ojs2.jchr.org:article/17755","doi":null,"is_oa":true,"landing_page_url":"https://jchr.org/index.php/JCHR/article/view/17755","pdf_url":"https://jchr.org/index.php/JCHR/article/download/17755/9430","source":{"id":"https://openalex.org/S2764499610","display_name":"Journal of chemical health risks","issn_l":"2251-6719","issn":["2251-6719","2251-6727"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310319124","host_organization_name":"Azad University Cross Team","host_organization_lineage":["https://openalex.org/P4310319124"],"host_organization_lineage_names":["Azad University Cross Team"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2251-6719","raw_type":"info:eu-repo/semantics/article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://jchr.org/index.php/JCHR/article/download/17755/9430","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5160393937","display_name":"Chetan S. Dolas","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Chetan S. Dolas","raw_affiliation_strings":["Department of Biochemistry , Institute of Biosciences and Technology , MGM University , ChhatrapatiSambhajinagar , 431003 ; Maharashtra , India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry , Institute of Biosciences and Technology , MGM University , ChhatrapatiSambhajinagar , 431003 ; Maharashtra , India","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5160393937"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.82566112,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11319","display_name":"Curcumin's Biomedical Applications","score":0.8515999913215637,"subfield":{"id":"https://openalex.org/subfields/1313","display_name":"Molecular Medicine"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11319","display_name":"Curcumin's Biomedical Applications","score":0.8515999913215637,"subfield":{"id":"https://openalex.org/subfields/1313","display_name":"Molecular Medicine"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12347","display_name":"Ginger and Zingiberaceae research","score":0.10970000177621841,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.011800000444054604,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/turmeric","display_name":"turmeric","score":1.0},{"id":"https://openalex.org/keywords/turmeric-rhizome","display_name":"turmeric rhizome","score":0.8769999742507935},{"id":"https://openalex.org/keywords/extractants","display_name":"extraction solvents","score":0.5709999799728394},{"id":"https://openalex.org/keywords/ethanol-extract","display_name":"ethanol extract","score":0.843999981880188},{"id":"https://openalex.org/keywords/acetone-extract","display_name":"acetone extract","score":1.0},{"id":"https://openalex.org/keywords/hplc-fingerprint","display_name":"HPLC fingerprint","score":0.8610000014305115},{"id":"https://openalex.org/keywords/curcumin","display_name":"curcumin","score":0.7639999985694885},{"id":"https://openalex.org/keywords/phytochemical-profile","display_name":"phytochemical composition","score":0.8510000109672546},{"id":"https://openalex.org/keywords/cytotoxicity","display_name":"cytotoxicity","score":0.9919999837875366},{"id":"https://openalex.org/keywords/kb-cells","display_name":"KB cells","score":0.8289999961853027},{"id":"https://openalex.org/keywords/oral-cancer","display_name":"oral cancer","score":0.7670000195503235},{"id":"https://openalex.org/keywords/anticancer-activity","display_name":"anticancer activity","score":0.4909999966621399}],"concepts":[{"id":"https://openalex.org/C134550120","wikidata":"https://www.wikidata.org/wiki/Q184208","display_name":"Rhizome","level":2,"score":0.9093999862670898},{"id":"https://openalex.org/C195475562","wikidata":"https://www.wikidata.org/wiki/Q1639139","display_name":"Phytochemical","level":2,"score":0.86080002784729},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8163999915122986},{"id":"https://openalex.org/C2777230291","wikidata":"https://www.wikidata.org/wiki/Q33551","display_name":"Curcuma","level":2,"score":0.7603999972343445},{"id":"https://openalex.org/C2781213060","wikidata":"https://www.wikidata.org/wiki/Q49546","display_name":"Acetone","level":2,"score":0.7451000213623047},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.7141000032424927},{"id":"https://openalex.org/C4725764","wikidata":"https://www.wikidata.org/wiki/Q844704","display_name":"Extraction (chemistry)","level":2,"score":0.6722999811172485},{"id":"https://openalex.org/C179998833","wikidata":"https://www.wikidata.org/wiki/Q381233","display_name":"High-performance liquid chromatography","level":2,"score":0.5967000126838684},{"id":"https://openalex.org/C2776789170","wikidata":"https://www.wikidata.org/wiki/Q37021","display_name":"Zingiberaceae","level":3,"score":0.5849999785423279},{"id":"https://openalex.org/C2780161600","wikidata":"https://www.wikidata.org/wiki/Q153","display_name":"Ethanol","level":2,"score":0.5339000225067139},{"id":"https://openalex.org/C2780471494","wikidata":"https://www.wikidata.org/wiki/Q146505","display_name":"Solvent","level":2,"score":0.527899980545044},{"id":"https://openalex.org/C109316439","wikidata":"https://www.wikidata.org/wiki/Q246181","display_name":"Cytotoxicity","level":3,"score":0.45570001006126404},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.39259999990463257},{"id":"https://openalex.org/C2780783641","wikidata":"https://www.wikidata.org/wiki/Q738686","display_name":"MTT assay","level":3,"score":0.3246000111103058},{"id":"https://openalex.org/C2778564307","wikidata":"https://www.wikidata.org/wiki/Q207653","display_name":"Saponin","level":3,"score":0.2874999940395355},{"id":"https://openalex.org/C160492267","wikidata":"https://www.wikidata.org/wiki/Q319616","display_name":"Pharmacognosy","level":4,"score":0.27549999952316284}],"mesh":[],"locations_count":1,"locations":[{"id":"pmh:oai:ojs2.jchr.org:article/17755","doi":null,"is_oa":true,"landing_page_url":"https://jchr.org/index.php/JCHR/article/view/17755","pdf_url":"https://jchr.org/index.php/JCHR/article/download/17755/9430","source":{"id":"https://openalex.org/S2764499610","display_name":"Journal of chemical health risks","issn_l":"2251-6719","issn":["2251-6719","2251-6727"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310319124","host_organization_name":"Azad University Cross Team","host_organization_lineage":["https://openalex.org/P4310319124"],"host_organization_lineage_names":["Azad University Cross Team"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2251-6719","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:ojs2.jchr.org:article/17755","doi":null,"is_oa":true,"landing_page_url":"https://jchr.org/index.php/JCHR/article/view/17755","pdf_url":"https://jchr.org/index.php/JCHR/article/download/17755/9430","source":{"id":"https://openalex.org/S2764499610","display_name":"Journal of chemical health risks","issn_l":"2251-6719","issn":["2251-6719","2251-6727"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310319124","host_organization_name":"Azad University Cross Team","host_organization_lineage":["https://openalex.org/P4310319124"],"host_organization_lineage_names":["Azad University Cross Team"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2251-6719","raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[{"score":0.428600013256073,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7225218954.pdf","grobid_xml":"https://content.openalex.org/works/W7225218954.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4200178634","https://openalex.org/W4382646340","https://openalex.org/W2161048359","https://openalex.org/W2090724449","https://openalex.org/W4390637286","https://openalex.org/W2948268233","https://openalex.org/W4295206771","https://openalex.org/W2465774066","https://openalex.org/W2945341635","https://openalex.org/W4313365189"],"abstract_inverted_index":{"Aim:":[0],"The":[1,40,64,91,124,142,157],"aim":[2],"of":[3,15,29,46,57,70,73,84,122,160,206,240],"this":[4],"study":[5,66],"was":[6,151,163,195,252],"to":[7,25,270],"document":[8],"the":[9,27,36,55,60,68,71,79,129,154,168,172,207,215,234,247,253,272],"phytochemical":[10,41,107],"composition":[11,42],"and":[12,24,32,43,59,75,82,89,93,101,109,138,176,184,204,225,230,237,251,265,275],"biological":[13,44,278],"activities":[14],"curcuma":[16,47],"longa":[17,48,242],"L.":[18,49],"rhizomes":[19,50,95],"prepared":[20],"using":[21,117,128,153],"different":[22],"solvents":[23,31],"identify":[26,271],"impact":[28],"these":[30],"extraction":[33,61,76,231],"methods":[34],"on":[35,54,78,145],"compounds":[37],"present.":[38],"Background:":[39],"activity":[45,144,250],"may":[51],"vary":[52],"depending":[53],"type":[56,72,229],"rhizome":[58,74],"solvent":[62,77,232],"used.":[63],"present":[65],"compared":[67,127],"effect":[69],"chromatographic":[80,235],"profile":[81],"cytotoxicity":[83,217],"extracts":[85,178],"from":[86],"C.":[87,241],"longa.Materials":[88],"Methods:":[90],"mother":[92],"finger":[94],"were":[96,114,126],"extracted":[97],"separately":[98],"with":[99],"acetone":[100,190],"ethanol":[102],"by":[103,220],"Soxhlet":[104],"extraction.":[105],"A":[106],"screening":[108],"reversed":[110],"phase":[111],"HPLC":[112],"analysis":[113],"carried":[115],"out":[116],"an":[118],"authentic":[119],"reference":[120],"standard":[121,162],"curcumin.":[123],"chromatograms":[125],"following":[130],"comparisons:":[131],"retention":[132,158],"time,":[133],"peak":[134,136,140,194,209],"area,":[135,210],"height":[137],"relative":[139,208],"abundance.":[141],"cytotoxic":[143,238,249],"KB":[146],"(human":[147],"oral":[148],"cancer)":[149],"cells":[150],"measured":[152],"MTT":[155],"assay.Results:":[156],"time":[159],"curcumin":[161],"about":[164],"3.02":[165],"min,":[166,186,199],"while":[167],"major":[169],"peaks":[170],"in":[171],"finger\u2013ethanol,":[173],"mother\u2013ethanol,":[174],"finger\u2013acetone":[175],"mother\u2013acetone":[177,221],"occurred":[179],"at":[180,197],"4.87,":[181],"3.93,":[182],"3.87":[183],"3.85":[185],"respectively.":[187,211],"In":[188],"both":[189],"extracts,":[191],"a":[192],"second":[193],"observed":[196],"3.19":[198],"which":[200],"made":[201],"up":[202],"2.62%":[203],"7.59%":[205],"Finger\u2013acetone":[212,244],"extract":[213,245],"exhibited":[214],"highest":[216],"(86.96%)":[218],"followed":[219],"(80.36%),":[222],"finger\u2013ethanol":[223],"(61.31%)":[224],"mother\u2013ethanol":[226],"(51.11%).Conclusion:":[227],"Rhizome":[228],"influenced":[233],"characteristics":[236],"response":[239],"extracts.":[243],"demonstrated":[246],"strongest":[248],"most":[254],"promising":[255],"preparation.":[256],"Further":[257],"validated":[258],"HPLC/PDA":[259],"or":[260],"LC\u2013MS/MS":[261],"studies,":[262],"dose\u2013response":[263],"evaluation,":[264],"mechanistic":[266],"investigations":[267],"are":[268],"warranted":[269],"active":[273],"constituents":[274],"clarify":[276],"their":[277],"effects.":[279]},"counts_by_year":[],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2026-11-04T00:00:00"}