{"id":"https://openalex.org/W7225192567","doi":"https://doi.org/10.55885/jchp.v6i3.1207","title":"Literature Review of the Potential of Miana Leaf Extract as an Antibacterial Agent Against Escherichia coli in Urinary Tract Infections","display_name":"Literature Review of the Potential of Miana Leaf Extract as an Antibacterial Agent Against Escherichia coli in Urinary Tract Infections","publication_year":2026,"publication_date":"2026-11-03","ids":{"openalex":"https://openalex.org/W7225192567","doi":"https://doi.org/10.55885/jchp.v6i3.1207"},"language":"en","primary_location":{"id":"doi:10.55885/jchp.v6i3.1207","doi":"https://doi.org/10.55885/jchp.v6i3.1207","is_oa":true,"landing_page_url":"https://doi.org/10.55885/jchp.v6i3.1207","pdf_url":"https://psppjournals.org/index.php/jchp/article/download/1207/1167","source":{"id":"https://openalex.org/S4387279635","display_name":"Journal of Community Health Provision","issn_l":"2776-1150","issn":["2776-1150","2776-1169"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Community Health Provision","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://psppjournals.org/index.php/jchp/article/download/1207/1167","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5094207658","display_name":"Andini Marccela","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210116576","display_name":"Universitas Muslim Indonesia","ror":"https://ror.org/02c0s8023","country_code":"ID","type":"education","lineage":["https://openalex.org/I4210116576"]}],"countries":["ID"],"is_corresponding":false,"raw_author_name":"Andini Marccela","raw_affiliation_strings":["Universitas Muslim Indonesia, Makassar, Indonesia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universitas Muslim Indonesia, Makassar, Indonesia","institution_ids":["https://openalex.org/I4210116576"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036515695","display_name":"Yusriani Mangarengi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210116576","display_name":"Universitas Muslim Indonesia","ror":"https://ror.org/02c0s8023","country_code":"ID","type":"education","lineage":["https://openalex.org/I4210116576"]}],"countries":["ID"],"is_corresponding":false,"raw_author_name":"Yusriani Mangarengi","raw_affiliation_strings":["Universitas Muslim Indonesia, Makassar, Indonesia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universitas Muslim Indonesia, Makassar, Indonesia","institution_ids":["https://openalex.org/I4210116576"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5117211300","display_name":"Tiradewi Bustami","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210116576","display_name":"Universitas Muslim Indonesia","ror":"https://ror.org/02c0s8023","country_code":"ID","type":"education","lineage":["https://openalex.org/I4210116576"]}],"countries":["ID"],"is_corresponding":false,"raw_author_name":"Tiradewi Bustami","raw_affiliation_strings":["Universitas Muslim Indonesia, Makassar, Indonesia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universitas Muslim Indonesia, Makassar, Indonesia","institution_ids":["https://openalex.org/I4210116576"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210116576"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.8213879,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"6","issue":"3","first_page":"1138","last_page":"1148"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10225","display_name":"Essential Oils and Antimicrobial Activity","score":0.9721999764442444,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10225","display_name":"Essential Oils and Antimicrobial Activity","score":0.9721999764442444,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11232","display_name":"Urinary Tract Infections Management","score":0.020600000396370888,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.004900000058114529,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/coleus-scutellarioides","display_name":"Coleus scutellarioides","score":0.9980000257492065},{"id":"https://openalex.org/keywords/escherichia-coli","display_name":"Escherichia coli","score":0.9800000190734863},{"id":"https://openalex.org/keywords/urinary-tract-infection","display_name":"urinary tract infection","score":0.9940000176429749},{"id":"https://openalex.org/keywords/antibacterial-activity","display_name":"antibacterial activity","score":0.9860000014305115},{"id":"https://openalex.org/keywords/natural-antibacterial-agents","display_name":"natural antibacterial agents","score":0.9190000295639038},{"id":"https://openalex.org/keywords/bioactive-compounds","display_name":"bioactive compounds","score":0.5809999704360962},{"id":"https://openalex.org/keywords/flavonoids","display_name":"flavonoids","score":0.8169999718666077},{"id":"https://openalex.org/keywords/tannins","display_name":"tannins","score":0.8759999871253967},{"id":"https://openalex.org/keywords/saponins","display_name":"saponins","score":0.9539999961853027},{"id":"https://openalex.org/keywords/alkaloids","display_name":"alkaloids","score":0.7480000257492065},{"id":"https://openalex.org/keywords/essential-oils","display_name":"essential oils","score":0.9660000205039978},{"id":"https://openalex.org/keywords/bacterial-membrane-disruption","display_name":"bacterial membrane disruption","score":0.6930000185966492},{"id":"https://openalex.org/keywords/antibiotic-resistance","display_name":"antibiotic resistance","score":0.75},{"id":"https://openalex.org/keywords/biofilm","display_name":"biofilm","score":0.7160000205039978}],"concepts":[{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.8123000264167786},{"id":"https://openalex.org/C2780104969","wikidata":"https://www.wikidata.org/wiki/Q4774530","display_name":"Antibacterial activity","level":3,"score":0.7128999829292297},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.6545000076293945},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.6162999868392944},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5455999970436096},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.531000018119812},{"id":"https://openalex.org/C4937899","wikidata":"https://www.wikidata.org/wiki/Q68541106","display_name":"Antimicrobial","level":2,"score":0.4925000071525574},{"id":"https://openalex.org/C3019249092","wikidata":"https://www.wikidata.org/wiki/Q274493","display_name":"Antibacterial agent","level":3,"score":0.48910000920295715},{"id":"https://openalex.org/C58123911","wikidata":"https://www.wikidata.org/wiki/Q467410","display_name":"Biofilm","level":3,"score":0.44119998812675476},{"id":"https://openalex.org/C94665300","wikidata":"https://www.wikidata.org/wiki/Q63391344","display_name":"Antibiotic resistance","level":3,"score":0.4375},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.40959998965263367},{"id":"https://openalex.org/C77411442","wikidata":"https://www.wikidata.org/wiki/Q181100","display_name":"Urinary system","level":2,"score":0.40700000524520874},{"id":"https://openalex.org/C2778910516","wikidata":"https://www.wikidata.org/wiki/Q380136","display_name":"Enterobacteriaceae","level":4,"score":0.39070001244544983},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.3790000081062317},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.3425999879837036},{"id":"https://openalex.org/C115574571","wikidata":"https://www.wikidata.org/wiki/Q183119","display_name":"Bacteriocin","level":3,"score":0.31859999895095825},{"id":"https://openalex.org/C114851261","wikidata":"https://www.wikidata.org/wiki/Q12147416","display_name":"Drug resistance","level":2,"score":0.3165000081062317},{"id":"https://openalex.org/C2776985332","wikidata":"https://www.wikidata.org/wiki/Q311055","display_name":"Escherichia","level":4,"score":0.3124000132083893},{"id":"https://openalex.org/C176947019","wikidata":"https://www.wikidata.org/wiki/Q597889","display_name":"Minimum inhibitory concentration","level":3,"score":0.30399999022483826},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.29490000009536743},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.25929999351501465}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.55885/jchp.v6i3.1207","doi":"https://doi.org/10.55885/jchp.v6i3.1207","is_oa":true,"landing_page_url":"https://doi.org/10.55885/jchp.v6i3.1207","pdf_url":"https://psppjournals.org/index.php/jchp/article/download/1207/1167","source":{"id":"https://openalex.org/S4387279635","display_name":"Journal of Community Health Provision","issn_l":"2776-1150","issn":["2776-1150","2776-1169"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Community Health Provision","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.55885/jchp.v6i3.1207","doi":"https://doi.org/10.55885/jchp.v6i3.1207","is_oa":true,"landing_page_url":"https://doi.org/10.55885/jchp.v6i3.1207","pdf_url":"https://psppjournals.org/index.php/jchp/article/download/1207/1167","source":{"id":"https://openalex.org/S4387279635","display_name":"Journal of Community Health Provision","issn_l":"2776-1150","issn":["2776-1150","2776-1169"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Community Health Provision","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8999999761581421,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7225192567.pdf","grobid_xml":"https://content.openalex.org/works/W7225192567.grobid-xml"},"referenced_works_count":29,"referenced_works":["https://openalex.org/W2778059707","https://openalex.org/W2895424644","https://openalex.org/W3159428160","https://openalex.org/W3199070946","https://openalex.org/W3215294119","https://openalex.org/W4229021155","https://openalex.org/W4281639938","https://openalex.org/W4286285581","https://openalex.org/W4295346553","https://openalex.org/W4310714836","https://openalex.org/W4317616796","https://openalex.org/W4327739805","https://openalex.org/W4366691493","https://openalex.org/W4368341233","https://openalex.org/W4382181711","https://openalex.org/W4382459791","https://openalex.org/W4385420343","https://openalex.org/W4390085117","https://openalex.org/W4390455945","https://openalex.org/W4401200895","https://openalex.org/W4401465860","https://openalex.org/W4403714105","https://openalex.org/W4404327993","https://openalex.org/W4411291407","https://openalex.org/W4411612456","https://openalex.org/W7142766533","https://openalex.org/W7166447203","https://openalex.org/W7168369384","https://openalex.org/W7212111063"],"related_works":["https://openalex.org/W7128468190","https://openalex.org/W4410103406","https://openalex.org/W2185306312","https://openalex.org/W2976268096","https://openalex.org/W4210851565","https://openalex.org/W4399383501","https://openalex.org/W4416911674","https://openalex.org/W7218132567","https://openalex.org/W2182888553","https://openalex.org/W4410470147"],"abstract_inverted_index":{"Urinary":[0],"tract":[1],"infections":[2],"(UTIs)":[3],"are":[4,243],"among":[5],"the":[6,16,34,67,134,141],"most":[7],"common":[8],"infectious":[9],"diseases,":[10],"with":[11,81,175,188],"Escherichia":[12],"coli":[13,24,79],"recognized":[14],"as":[15,73,218],"predominant":[17],"causative":[18],"pathogen.":[19],"The":[20,143],"ability":[21],"of":[22,36,69,122],"E.":[23,78,125,154,224],"to":[25,65,113,161,245],"form":[26],"biofilms":[27],"and":[28,54,94,100,106,120,137,168,190,193,240,250],"increasing":[29],"antibiotic":[30],"resistance":[31],"have":[32],"encouraged":[33],"exploration":[35],"natural":[37,220],"antibacterial":[38,60,75,117,151,221],"agents.":[39],"Miana":[40],"leaves":[41],"(Coleus":[42],"scutellarioides":[43],"(L.)":[44],"Benth.)":[45],"contain":[46],"bioactive":[47],"compounds,":[48],"including":[49],"flavonoids,":[50],"tannins,":[51],"saponins,":[52],"alkaloids,":[53],"essential":[55],"oils,":[56],"which":[57],"may":[58,179],"exhibit":[59],"properties.":[61],"This":[62,171],"study":[63],"aimed":[64],"evaluate":[66],"potential":[68,217,255],"miana":[70,114,147,213],"leaf":[71,115,148,214],"extract":[72,149,162,199,215],"an":[74],"agent":[76,222],"against":[77,124,153,223],"associated":[80,174],"UTIs.":[82],"A":[83],"narrative":[84],"literature":[85],"review":[86],"was":[87],"conducted":[88],"using":[89],"secondary":[90,176],"data":[91],"from":[92],"national":[93],"international":[95],"scientific":[96],"journals,":[97],"ClinicalKey,":[98],"textbooks,":[99],"conference":[101],"proceedings":[102],"published":[103],"between":[104],"2020":[105],"2026.":[107],"Literature":[108],"selection":[109],"focused":[110],"on":[111,232],"relevance":[112],"extract,":[116],"activity,":[118,192],"effectiveness,":[119,248],"mechanisms":[121],"action":[123],"coli.":[126,225],"Of":[127],"531":[128],"initially":[129],"identified":[130],"articles,":[131],"10":[132],"met":[133],"eligibility":[135],"criteria":[136],"were":[138],"included":[139],"in":[140,233,237,257],"review.":[142],"findings":[144],"indicate":[145],"that":[146,178],"exhibits":[150],"activity":[152,172],"coli,":[155],"although":[156,206],"its":[157,247,254],"effectiveness":[158],"varies":[159],"according":[160],"concentration,":[163],"extraction":[164],"method,":[165],"solvent":[166],"type,":[167],"experimental":[169],"conditions.":[170],"is":[173,229],"metabolites":[177],"disrupt":[180],"bacterial":[181,195],"cell":[182],"membranes,":[183],"alter":[184],"membrane":[185],"permeability,":[186],"interfere":[187],"protein":[189],"enzymatic":[191],"impair":[194],"metabolic":[196],"processes.":[197],"Higher":[198],"concentrations":[200],"generally":[201],"demonstrate":[202],"greater":[203],"inhibitory":[204],"effects,":[205],"results":[207],"vary":[208],"across":[209],"studies.":[210,235],"In":[211],"conclusion,":[212],"has":[216],"a":[219],"However,":[226],"existing":[227],"evidence":[228],"predominantly":[230],"based":[231],"vitro":[234],"Further":[236],"vivo":[238],"research":[239],"clinical":[241],"trials":[242],"necessary":[244],"establish":[246],"safety,":[249],"optimal":[251],"concentration":[252],"before":[253],"application":[256],"UTI":[258],"treatment.":[259]},"counts_by_year":[],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2026-11-04T00:00:00"}