{"id":"https://openalex.org/W7225174451","doi":"https://doi.org/10.1002/anr3.70117","title":"Double\u2010lumen tube insertion and one\u2010lung ventilation in Coffin\u2013Siris syndrome: navigating airway challenges in severe scoliosis surgery*","display_name":"Double\u2010lumen tube insertion and one\u2010lung ventilation in Coffin\u2013Siris syndrome: navigating airway challenges in severe scoliosis surgery*","publication_year":2026,"publication_date":"2026-07-01","ids":{"openalex":"https://openalex.org/W7225174451","doi":"https://doi.org/10.1002/anr3.70117","pmid":"https://pubmed.ncbi.nlm.nih.gov/42979124","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13728542"},"language":"en","primary_location":{"id":"doi:10.1002/anr3.70117","doi":"https://doi.org/10.1002/anr3.70117","is_oa":true,"landing_page_url":"https://doi.org/10.1002/anr3.70117","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/anr3.70117","source":{"id":"https://openalex.org/S4210224924","display_name":"Anaesthesia Reports","issn_l":"2637-3726","issn":["2637-3726"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Anaesthesia Reports","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/anr3.70117","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5160475871","display_name":"Talia L. Y. Lim","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210146690","display_name":"National University Hospital","ror":"https://ror.org/04fp9fm22","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I165932596","https://openalex.org/I4210146690","https://openalex.org/I4210150261"]}],"countries":["SG"],"is_corresponding":true,"raw_author_name":"Talia L. Y. Lim","raw_affiliation_strings":["Department of Anaesthesia National University Hospital  Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anaesthesia National University Hospital  Singapore","institution_ids":["https://openalex.org/I4210146690"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5018673585","display_name":"Simone Misquita","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210146690","display_name":"National University Hospital","ror":"https://ror.org/04fp9fm22","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I165932596","https://openalex.org/I4210146690","https://openalex.org/I4210150261"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Simone Misquita","raw_affiliation_strings":["Department of Anaesthesia National University Hospital  Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Anaesthesia National University Hospital  Singapore","institution_ids":["https://openalex.org/I4210146690"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5160475871"],"corresponding_institution_ids":["https://openalex.org/I4210146690"],"apc_list":{"value":1300,"currency":"USD","value_usd":1300},"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.89347914,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"14","issue":"2","first_page":"e70117","last_page":"e70117"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10830","display_name":"Airway Management and Intubation Techniques","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10830","display_name":"Airway Management and Intubation Techniques","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10436","display_name":"Anesthesia and Sedative Agents","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2703","display_name":"Anesthesiology and Pain Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11260","display_name":"Tracheal and airway disorders","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/coffin-siris-syndrome","display_name":"Coffin-Siris syndrome","score":0.9990000128746033},{"id":"https://openalex.org/keywords/one-lung-ventilation","display_name":"one-lung ventilation","score":0.9990000128746033},{"id":"https://openalex.org/keywords/difficult-airway-management","display_name":"difficult airway management","score":0.8640000224113464},{"id":"https://openalex.org/keywords/airway-malacia","display_name":"airway malacia","score":0.7260000109672546},{"id":"https://openalex.org/keywords/bronchomalacia","display_name":"bronchomalacia","score":0.7900000214576721},{"id":"https://openalex.org/keywords/hypotonia","display_name":"hypotonia","score":0.871999979019165},{"id":"https://openalex.org/keywords/total-intravenous-anesthesia","display_name":"total intravenous anesthesia","score":0.7590000033378601},{"id":"https://openalex.org/keywords/dexmedetomidine","display_name":"dexmedetomidine","score":0.8529999852180481},{"id":"https://openalex.org/keywords/video-laryngoscopy","display_name":"video laryngoscopy","score":0.8809999823570251},{"id":"https://openalex.org/keywords/pediatric-anesthesia","display_name":"pediatric anesthesia","score":0.7080000042915344},{"id":"https://openalex.org/keywords/atelectasis","display_name":"atelectasis","score":0.49900001287460327}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8960999846458435},{"id":"https://openalex.org/C2778112660","wikidata":"https://www.wikidata.org/wiki/Q1340889","display_name":"Tracheal tube","level":3,"score":0.7430999875068665},{"id":"https://openalex.org/C105922876","wikidata":"https://www.wikidata.org/wiki/Q1423981","display_name":"Airway","level":2,"score":0.6448000073432922},{"id":"https://openalex.org/C2781101014","wikidata":"https://www.wikidata.org/wiki/Q754031","display_name":"Atelectasis","level":3,"score":0.644599974155426},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.6367999911308289},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.5565999746322632},{"id":"https://openalex.org/C200457457","wikidata":"https://www.wikidata.org/wiki/Q584049","display_name":"Ventilation (architecture)","level":2,"score":0.48669999837875366},{"id":"https://openalex.org/C2780955175","wikidata":"https://www.wikidata.org/wiki/Q174857","display_name":"Scoliosis","level":2,"score":0.46860000491142273},{"id":"https://openalex.org/C2778974821","wikidata":"https://www.wikidata.org/wiki/Q910455","display_name":"Tracheomalacia","level":3,"score":0.4602000117301941},{"id":"https://openalex.org/C2780978852","wikidata":"https://www.wikidata.org/wiki/Q286949","display_name":"Airway management","level":3,"score":0.45419999957084656},{"id":"https://openalex.org/C2778029997","wikidata":"https://www.wikidata.org/wiki/Q750195","display_name":"Tracheal intubation","level":3,"score":0.451200008392334},{"id":"https://openalex.org/C163100246","wikidata":"https://www.wikidata.org/wiki/Q1064483","display_name":"Prone position","level":2,"score":0.4066999852657318},{"id":"https://openalex.org/C2778716859","wikidata":"https://www.wikidata.org/wiki/Q939018","display_name":"Intubation","level":2,"score":0.39969998598098755},{"id":"https://openalex.org/C2777080012","wikidata":"https://www.wikidata.org/wiki/Q3766250","display_name":"Mechanical ventilation","level":2,"score":0.3528999984264374},{"id":"https://openalex.org/C2908550248","wikidata":"https://www.wikidata.org/wiki/Q4116448","display_name":"Tracheal Stenosis","level":3,"score":0.31850001215934753},{"id":"https://openalex.org/C2777551473","wikidata":"https://www.wikidata.org/wiki/Q2093072","display_name":"Tube (container)","level":2,"score":0.3172000050544739},{"id":"https://openalex.org/C2778551211","wikidata":"https://www.wikidata.org/wiki/Q324921","display_name":"Tracheotomy","level":2,"score":0.28110000491142273},{"id":"https://openalex.org/C2778333281","wikidata":"https://www.wikidata.org/wiki/Q4330029","display_name":"Airway obstruction","level":3,"score":0.2770000100135803},{"id":"https://openalex.org/C2781245598","wikidata":"https://www.wikidata.org/wiki/Q5182134","display_name":"Craniofacial","level":2,"score":0.2700999975204468},{"id":"https://openalex.org/C2778996910","wikidata":"https://www.wikidata.org/wiki/Q237232","display_name":"Bronchoscopy","level":2,"score":0.25920000672340393}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1002/anr3.70117","doi":"https://doi.org/10.1002/anr3.70117","is_oa":true,"landing_page_url":"https://doi.org/10.1002/anr3.70117","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/anr3.70117","source":{"id":"https://openalex.org/S4210224924","display_name":"Anaesthesia Reports","issn_l":"2637-3726","issn":["2637-3726"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Anaesthesia Reports","raw_type":"journal-article"},{"id":"pmid:42979124","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42979124","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Anaesthesia reports","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13728542","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13728542/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Anaesth Rep","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1002/anr3.70117","doi":"https://doi.org/10.1002/anr3.70117","is_oa":true,"landing_page_url":"https://doi.org/10.1002/anr3.70117","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/anr3.70117","source":{"id":"https://openalex.org/S4210224924","display_name":"Anaesthesia Reports","issn_l":"2637-3726","issn":["2637-3726"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","poland-20","russia-white-list-4"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Anaesthesia Reports","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.979200005531311,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7225174451.pdf","grobid_xml":"https://content.openalex.org/works/W7225174451.grobid-xml"},"referenced_works_count":5,"referenced_works":["https://openalex.org/W2519213757","https://openalex.org/W2725350711","https://openalex.org/W2966441447","https://openalex.org/W4327886454","https://openalex.org/W4394571604"],"related_works":["https://openalex.org/W2418973032","https://openalex.org/W2519213757","https://openalex.org/W2406083570","https://openalex.org/W2725350711","https://openalex.org/W2091587120","https://openalex.org/W2069566835","https://openalex.org/W1811234","https://openalex.org/W2906053523","https://openalex.org/W2419594921","https://openalex.org/W2468232780"],"abstract_inverted_index":{"Coffin-Siris":[0,36,179],"syndrome":[1,37],"is":[2,203],"a":[3,32,45,70,152,176,187],"rare":[4,197],"genetic":[5],"condition":[6],"associated":[7],"with":[8,35,74,79,134,178,196],"craniofacial":[9],"and":[10,16,25,49,62,108,117,141,146,172],"skeletal":[11],"anomalies,":[12],"hypotonia,":[13,113],"airway":[14,23,110,131],"malacia":[15],"intellectual":[17],"disability,":[18],"posing":[19],"significant":[20],"challenges":[21],"for":[22,155],"management":[24],"ventilation.":[26,51],"We":[27,157],"report":[28],"the":[29,93,147,162,184,200],"case":[30,165,182],"of":[31,44,166,186],"13-year-old":[33],"patient":[34,148,177],"undergoing":[38],"anterior":[39],"scoliosis":[40],"surgery":[41],"requiring":[42],"insertion":[43],"double-lumen":[46,87,168],"tracheal":[47,88,101,169],"tube":[48,89,102,170],"one-lung":[50,126,173],"Pre-operative":[52,66],"assessment":[53],"identified":[54],"near-complete":[55],"C2-3":[56],"fusion,":[57],"severe":[58],"kyphoscoliosis,":[59],"pulmonary":[60],"atelectasis":[61,118],"difficult":[63],"intravenous":[64,81],"access.":[65],"intranasal":[67],"dexmedetomidine":[68],"enabled":[69],"smooth":[71],"inhalational":[72],"induction":[73],"sevoflurane.":[75],"Anaesthesia":[76],"was":[77,90,104,124,144,149],"maintained":[78],"total":[80],"anaesthesia.":[82],"A":[83],"28":[84],"Fr":[85],"left-sided":[86],"inserted":[91],"on":[92],"first":[94,163],"attempt":[95],"using":[96],"videolaryngoscopy.":[97],"However,":[98],"confirming":[99],"correct":[100,122],"position":[103],"challenging.":[105],"Thick":[106],"secretions":[107],"dynamic":[109],"collapse":[111],"from":[112],"bronchomalacia,":[114],"scoliosis-related":[115],"distortion":[116],"limited":[119],"visualisation.":[120],"Once":[121],"positioning":[123],"confirmed,":[125],"ventilation":[127,174],"commenced.":[128],"Initial":[129],"high":[130],"pressures":[132],"improved":[133],"ventilatory":[135],"adjustments,":[136],"achieving":[137],"adequate":[138],"tidal":[139],"volumes":[140],"oxygenation.":[142],"Surgery":[143],"uneventful":[145],"transferred":[150],"to":[151,160,191],"high-dependency":[153],"unit":[154],"observation.":[156],"believe":[158],"this":[159],"be":[161],"reported":[164],"successful":[167],"use":[171],"in":[175,194],"syndrome.":[180],"The":[181],"highlights":[183],"importance":[185],"structured":[188],"peri-operative":[189],"approach":[190],"optimise":[192],"safety":[193],"patients":[195],"syndromes":[198],"where":[199],"evidence":[201],"base":[202],"limited.":[204]},"counts_by_year":[],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2026-11-04T00:00:00"}