{"id":"https://openalex.org/W7225169907","doi":"https://doi.org/10.3390/jcto4040028","title":"Corneal Neovascularization: From Pathogenesis to Therapeutic Strategies","display_name":"Corneal Neovascularization: From Pathogenesis to Therapeutic Strategies","publication_year":2026,"publication_date":"2026-11-03","ids":{"openalex":"https://openalex.org/W7225169907","doi":"https://doi.org/10.3390/jcto4040028"},"language":"en","primary_location":{"id":"doi:10.3390/jcto4040028","doi":"https://doi.org/10.3390/jcto4040028","is_oa":true,"landing_page_url":"https://doi.org/10.3390/jcto4040028","pdf_url":null,"source":{"id":"https://openalex.org/S4387283673","display_name":"Journal of Clinical & Translational Ophthalmology","issn_l":"2813-1053","issn":["2813-1053"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical &amp; Translational Ophthalmology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.3390/jcto4040028","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084214714","display_name":"Basanta Bhujel","orcid":"https://orcid.org/0000-0002-0503-8900","observed_orcids":["https://orcid.org/0000-0002-0503-8900"]},"institutions":[{"id":"https://openalex.org/I2801680663","display_name":"Asan Medical Center","ror":"https://ror.org/03s5q0090","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I2801680663","https://openalex.org/I4210167194"]},{"id":"https://openalex.org/I40542001","display_name":"University of Ulsan","ror":"https://ror.org/02c2f8975","country_code":"KR","type":"education","lineage":["https://openalex.org/I40542001"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Basanta Bhujel","raw_affiliation_strings":["Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Republic of Korea"],"raw_orcid":"https://orcid.org/0000-0002-0503-8900","affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Republic of Korea","institution_ids":["https://openalex.org/I2801680663","https://openalex.org/I40542001"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057121502","display_name":"Kyu Sang Eah","orcid":"https://orcid.org/0000-0002-2598-9375","observed_orcids":["https://orcid.org/0000-0002-2598-9375"]},"institutions":[{"id":"https://openalex.org/I2801680663","display_name":"Asan Medical Center","ror":"https://ror.org/03s5q0090","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I2801680663","https://openalex.org/I4210167194"]},{"id":"https://openalex.org/I40542001","display_name":"University of Ulsan","ror":"https://ror.org/02c2f8975","country_code":"KR","type":"education","lineage":["https://openalex.org/I40542001"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Kyu Sang Eah","raw_affiliation_strings":["Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Republic of Korea"],"raw_orcid":"https://orcid.org/0000-0002-2598-9375","affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Republic of Korea","institution_ids":["https://openalex.org/I2801680663","https://openalex.org/I40542001"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100832476","display_name":"Soon Suk Kang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801680663","display_name":"Asan Medical Center","ror":"https://ror.org/03s5q0090","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I2801680663","https://openalex.org/I4210167194"]},{"id":"https://openalex.org/I40542001","display_name":"University of Ulsan","ror":"https://ror.org/02c2f8975","country_code":"KR","type":"education","lineage":["https://openalex.org/I40542001"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Soon Suk Kang","raw_affiliation_strings":["Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Republic of Korea","institution_ids":["https://openalex.org/I2801680663","https://openalex.org/I40542001"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017630073","display_name":"Hungwon Tchah","orcid":"https://orcid.org/0000-0002-0290-0120","observed_orcids":["https://orcid.org/0000-0002-0290-0120","https://orcid.org/0000-0002-8735-1684"]},"institutions":[{"id":"https://openalex.org/I2801680663","display_name":"Asan Medical Center","ror":"https://ror.org/03s5q0090","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I2801680663","https://openalex.org/I4210167194"]},{"id":"https://openalex.org/I40542001","display_name":"University of Ulsan","ror":"https://ror.org/02c2f8975","country_code":"KR","type":"education","lineage":["https://openalex.org/I40542001"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Ho Seok Chung","raw_affiliation_strings":["Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Republic of Korea"],"raw_orcid":"https://orcid.org/0000-0002-8735-1684","affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Republic of Korea","institution_ids":["https://openalex.org/I2801680663","https://openalex.org/I40542001"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5102846872","display_name":"Jae Yong Kim","orcid":"https://orcid.org/0000-0001-8571-8350","observed_orcids":["https://orcid.org/0000-0001-8571-8350"]},"institutions":[{"id":"https://openalex.org/I2801680663","display_name":"Asan Medical Center","ror":"https://ror.org/03s5q0090","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I2801680663","https://openalex.org/I4210167194"]},{"id":"https://openalex.org/I40542001","display_name":"University of Ulsan","ror":"https://ror.org/02c2f8975","country_code":"KR","type":"education","lineage":["https://openalex.org/I40542001"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Jae-Yong Kim","raw_affiliation_strings":["Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Republic of Korea"],"raw_orcid":"https://orcid.org/0000-0001-8571-8350","affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Republic of Korea","institution_ids":["https://openalex.org/I2801680663","https://openalex.org/I40542001"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5102846872"],"corresponding_institution_ids":["https://openalex.org/I2801680663","https://openalex.org/I40542001"],"apc_list":{"value":1000,"currency":"CHF","value_usd":1207},"apc_paid":{"value":1000,"currency":"CHF","value_usd":1207},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.89961956,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"4","issue":"4","first_page":"28","last_page":"28"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11828","display_name":"Corneal Surgery and Treatments","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11828","display_name":"Corneal Surgery and Treatments","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10563","display_name":"Corneal surgery and disorders","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11826","display_name":"Ocular Infections and Treatments","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/corneal-neovascularization","display_name":"corneal neovascularization","score":1.0},{"id":"https://openalex.org/keywords/angiogenesis","display_name":"angiogenesis","score":0.8019999861717224},{"id":"https://openalex.org/keywords/keratitis","display_name":"keratitis","score":0.9559999704360962},{"id":"https://openalex.org/keywords/corneal-injury","display_name":"corneal injury","score":0.7599999904632568},{"id":"https://openalex.org/keywords/corneal-scarring","display_name":"corneal scarring","score":0.7889999747276306},{"id":"https://openalex.org/keywords/corneal-opacity","display_name":"corneal opacity","score":0.8489999771118164},{"id":"https://openalex.org/keywords/vascular-regression","display_name":"vascular regression","score":0.7570000290870667},{"id":"https://openalex.org/keywords/anti-angiogenic-therapy","display_name":"anti-angiogenic therapy","score":0.9089999794960022},{"id":"https://openalex.org/keywords/corneal-transparency","display_name":"corneal transparency","score":0.7699999809265137}],"concepts":[{"id":"https://openalex.org/C2777844972","wikidata":"https://www.wikidata.org/wiki/Q1266519","display_name":"Corneal neovascularization","level":4,"score":0.7289000153541565},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.714900016784668},{"id":"https://openalex.org/C2778271429","wikidata":"https://www.wikidata.org/wiki/Q1281049","display_name":"Neovascularization","level":3,"score":0.6553999781608582},{"id":"https://openalex.org/C207886595","wikidata":"https://www.wikidata.org/wiki/Q1456138","display_name":"Pathological","level":2,"score":0.49549999833106995},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.4399999976158142},{"id":"https://openalex.org/C2776882836","wikidata":"https://www.wikidata.org/wiki/Q168291","display_name":"Cornea","level":2,"score":0.43880000710487366},{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.4185999929904938},{"id":"https://openalex.org/C2780394083","wikidata":"https://www.wikidata.org/wiki/Q539568","display_name":"Angiogenesis","level":2,"score":0.41600000858306885},{"id":"https://openalex.org/C2909399601","wikidata":"https://www.wikidata.org/wiki/Q168291","display_name":"Corneal Diseases","level":3,"score":0.4129999876022339},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.3425000011920929},{"id":"https://openalex.org/C2778384578","wikidata":"https://www.wikidata.org/wiki/Q16930687","display_name":"Therapeutic approach","level":3,"score":0.34119999408721924},{"id":"https://openalex.org/C2777863537","wikidata":"https://www.wikidata.org/wiki/Q357896","display_name":"Adjuvant","level":2,"score":0.3321000039577484},{"id":"https://openalex.org/C89611455","wikidata":"https://www.wikidata.org/wiki/Q6804646","display_name":"Mechanism (biology)","level":2,"score":0.3280999958515167},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3269999921321869},{"id":"https://openalex.org/C2909898526","wikidata":"https://www.wikidata.org/wiki/Q757838","display_name":"Corneal inflammation","level":3,"score":0.3167000114917755},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.30630001425743103},{"id":"https://openalex.org/C2777663904","wikidata":"https://www.wikidata.org/wiki/Q988343","display_name":"Blood vessel","level":2,"score":0.27880001068115234},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.2712000012397766},{"id":"https://openalex.org/C2779829184","wikidata":"https://www.wikidata.org/wiki/Q631361","display_name":"Diabetic retinopathy","level":3,"score":0.2621000111103058},{"id":"https://openalex.org/C2776992346","wikidata":"https://www.wikidata.org/wiki/Q111140","display_name":"Endothelium","level":2,"score":0.2563000023365021},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.2549999952316284}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.3390/jcto4040028","doi":"https://doi.org/10.3390/jcto4040028","is_oa":true,"landing_page_url":"https://doi.org/10.3390/jcto4040028","pdf_url":null,"source":{"id":"https://openalex.org/S4387283673","display_name":"Journal of Clinical & Translational Ophthalmology","issn_l":"2813-1053","issn":["2813-1053"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical &amp; Translational Ophthalmology","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.3390/jcto4040028","doi":"https://doi.org/10.3390/jcto4040028","is_oa":true,"landing_page_url":"https://doi.org/10.3390/jcto4040028","pdf_url":null,"source":{"id":"https://openalex.org/S4387283673","display_name":"Journal of Clinical & Translational Ophthalmology","issn_l":"2813-1053","issn":["2813-1053"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical &amp; Translational Ophthalmology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9476000070571899,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320322120","display_name":"National Research Foundation of Korea","ror":"https://ror.org/013aysd81"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":213,"referenced_works":["https://openalex.org/W334953415","https://openalex.org/W608522650","https://openalex.org/W1520090639","https://openalex.org/W1535159641","https://openalex.org/W1763323893","https://openalex.org/W1926771771","https://openalex.org/W1964569584","https://openalex.org/W1967881196","https://openalex.org/W1975672660","https://openalex.org/W1976918086","https://openalex.org/W1981246733","https://openalex.org/W1982229884","https://openalex.org/W1985833639","https://openalex.org/W1985834402","https://openalex.org/W1987369876","https://openalex.org/W1989786854","https://openalex.org/W1990397991","https://openalex.org/W1991311930","https://openalex.org/W1991681380","https://openalex.org/W1999635640","https://openalex.org/W2000688138","https://openalex.org/W2000801284","https://openalex.org/W2003797682","https://openalex.org/W2005567038","https://openalex.org/W2008850587","https://openalex.org/W2009053064","https://openalex.org/W2012852444","https://openalex.org/W2016933731","https://openalex.org/W2026530941","https://openalex.org/W2027533649","https://openalex.org/W2028256742","https://openalex.org/W2029126306","https://openalex.org/W2031046396","https://openalex.org/W2038451782","https://openalex.org/W2051168991","https://openalex.org/W2053675463","https://openalex.org/W2054122587","https://openalex.org/W2055503132","https://openalex.org/W2061445580","https://openalex.org/W2065691617","https://openalex.org/W2065957571","https://openalex.org/W2067879254","https://openalex.org/W2077021699","https://openalex.org/W2077022482","https://openalex.org/W2090248679","https://openalex.org/W2090433815","https://openalex.org/W2092838342","https://openalex.org/W2093044616","https://openalex.org/W2103057881","https://openalex.org/W2116112249","https://openalex.org/W2121438737","https://openalex.org/W2136581844","https://openalex.org/W2136843236","https://openalex.org/W2137452831","https://openalex.org/W2142038719","https://openalex.org/W2142045682","https://openalex.org/W2142266250","https://openalex.org/W2146980524","https://openalex.org/W2163141054","https://openalex.org/W2178299430","https://openalex.org/W2285549493","https://openalex.org/W2315089995","https://openalex.org/W2319259593","https://openalex.org/W2322225671","https://openalex.org/W2329828722","https://openalex.org/W2347071148","https://openalex.org/W2402323814","https://openalex.org/W2410262947","https://openalex.org/W2428433795","https://openalex.org/W2508916237","https://openalex.org/W2516928746","https://openalex.org/W2527224781","https://openalex.org/W2550936658","https://openalex.org/W2562849785","https://openalex.org/W2569450584","https://openalex.org/W2569623852","https://openalex.org/W2569920477","https://openalex.org/W2595421009","https://openalex.org/W2622491133","https://openalex.org/W2736973656","https://openalex.org/W2740964983","https://openalex.org/W2770869285","https://openalex.org/W2772906964","https://openalex.org/W2775455323","https://openalex.org/W2780942576","https://openalex.org/W2782295751","https://openalex.org/W2783366986","https://openalex.org/W2791164316","https://openalex.org/W2792358353","https://openalex.org/W2793157158","https://openalex.org/W2794088833","https://openalex.org/W2800900405","https://openalex.org/W2802868810","https://openalex.org/W2807717941","https://openalex.org/W2883748212","https://openalex.org/W2889131405","https://openalex.org/W2889508500","https://openalex.org/W2891253681","https://openalex.org/W2895385641","https://openalex.org/W2900390128","https://openalex.org/W2906646077","https://openalex.org/W2937163586","https://openalex.org/W2940517733","https://openalex.org/W2946667430","https://openalex.org/W2954863679","https://openalex.org/W2966366643","https://openalex.org/W2968517935","https://openalex.org/W2993727937","https://openalex.org/W2994865070","https://openalex.org/W3008399531","https://openalex.org/W3010918112","https://openalex.org/W3016478327","https://openalex.org/W3020647381","https://openalex.org/W3028808556","https://openalex.org/W3041016292","https://openalex.org/W3041260214","https://openalex.org/W3099132326","https://openalex.org/W3100373471","https://openalex.org/W3124025351","https://openalex.org/W3124974022","https://openalex.org/W3129923343","https://openalex.org/W3138451466","https://openalex.org/W3153933474","https://openalex.org/W3159744440","https://openalex.org/W3163880634","https://openalex.org/W3176185496","https://openalex.org/W3197510986","https://openalex.org/W3201063264","https://openalex.org/W3202892257","https://openalex.org/W3206038366","https://openalex.org/W3206754780","https://openalex.org/W3208845228","https://openalex.org/W3209891406","https://openalex.org/W4200229384","https://openalex.org/W4205379188","https://openalex.org/W4206206836","https://openalex.org/W4206267626","https://openalex.org/W4210573980","https://openalex.org/W4220910753","https://openalex.org/W4220969281","https://openalex.org/W4224291539","https://openalex.org/W4224443350","https://openalex.org/W4232505429","https://openalex.org/W4254918621","https://openalex.org/W4281553645","https://openalex.org/W4283758505","https://openalex.org/W4284961646","https://openalex.org/W4285005738","https://openalex.org/W4285007720","https://openalex.org/W4289833734","https://openalex.org/W4293858134","https://openalex.org/W4297403177","https://openalex.org/W4306367182","https://openalex.org/W4308937668","https://openalex.org/W4310537601","https://openalex.org/W4310599879","https://openalex.org/W4362474899","https://openalex.org/W4366393494","https://openalex.org/W4377141716","https://openalex.org/W4380370395","https://openalex.org/W4381252070","https://openalex.org/W4382753026","https://openalex.org/W4383954967","https://openalex.org/W4385157068","https://openalex.org/W4385577698","https://openalex.org/W4385994951","https://openalex.org/W4387830558","https://openalex.org/W4389348718","https://openalex.org/W4390394959","https://openalex.org/W4390588307","https://openalex.org/W4390858530","https://openalex.org/W4391005195","https://openalex.org/W4392517373","https://openalex.org/W4393375366","https://openalex.org/W4393391718","https://openalex.org/W4394008613","https://openalex.org/W4394979740","https://openalex.org/W4396607055","https://openalex.org/W4397007748","https://openalex.org/W4399051432","https://openalex.org/W4399180673","https://openalex.org/W4400479094","https://openalex.org/W4401439395","https://openalex.org/W4401510987","https://openalex.org/W4401834803","https://openalex.org/W4402356334","https://openalex.org/W4402731112","https://openalex.org/W4405331098","https://openalex.org/W4406080664","https://openalex.org/W4408098184","https://openalex.org/W4408288560","https://openalex.org/W4408732986","https://openalex.org/W4409497833","https://openalex.org/W4410071155","https://openalex.org/W4410788790","https://openalex.org/W4413688895","https://openalex.org/W4414352319","https://openalex.org/W4415168989","https://openalex.org/W4415255075","https://openalex.org/W4415379171","https://openalex.org/W4415943940","https://openalex.org/W4416456476","https://openalex.org/W4416572981","https://openalex.org/W7123439427","https://openalex.org/W7125374197","https://openalex.org/W7128176742","https://openalex.org/W7130650527","https://openalex.org/W7148571684","https://openalex.org/W7155042868","https://openalex.org/W7160180856","https://openalex.org/W7161715317","https://openalex.org/W7164409778","https://openalex.org/W7215131509"],"related_works":["https://openalex.org/W7224073304","https://openalex.org/W4409241845","https://openalex.org/W4211006688","https://openalex.org/W2064770374","https://openalex.org/W4394979740","https://openalex.org/W2582948118","https://openalex.org/W4293858134","https://openalex.org/W2098986957","https://openalex.org/W2038451782","https://openalex.org/W7123439427"],"abstract_inverted_index":{"Corneal":[0],"neovascularization":[1,79,106],"is":[2,37,49,122],"a":[3,40],"pathological":[4,161],"response":[5],"to":[6,181],"corneal":[7,26,78,105,162,183],"injury":[8],"and":[9,31,45,48,57,66,76,101,107,118,130,136,151,178,185],"inflammation":[10],"characterized":[11],"by":[12,39],"the":[13,20,67,99,131,146,157,172],"abnormal":[14],"growth":[15],"of":[16,69,74,98,133,167,174],"blood":[17],"vessels":[18],"into":[19],"normally":[21],"avascular":[22],"cornea,":[23],"resulting":[24],"in":[25,62],"opacity,":[27],"scarring,":[28],"lipid":[29],"deposition,":[30],"impaired":[32],"visual":[33,186],"function.":[34],"Its":[35],"development":[36,173],"driven":[38],"complex":[41],"imbalance":[42],"between":[43],"pro-":[44],"anti-angiogenic":[46],"factors":[47],"closely":[50],"associated":[51],"with":[52],"inflammatory":[53],"responses,":[54],"immune":[55],"activation,":[56],"tissue":[58],"remodelling.":[59],"Despite":[60],"advances":[61],"understanding":[63,166],"these":[64,168],"mechanisms":[65,103,159,169],"availability":[68],"various":[70],"treatments,":[71],"effective":[72,135,176],"management":[73],"persistent":[75],"established":[77,110],"remains":[80],"challenging,":[81],"particularly":[82],"because":[83],"existing":[84],"therapies":[85],"may":[86,170],"provide":[87],"incomplete":[88],"or":[89],"temporary":[90],"vascular":[91,138],"regression.":[92,139],"This":[93],"review":[94],"provides":[95],"an":[96],"overview":[97],"molecular":[100,117],"cellular":[102],"underlying":[104,160],"critically":[108],"evaluates":[109],"therapeutic":[111,126,153],"approaches,":[112],"as":[113,115],"well":[114],"emerging":[116],"adjuvant":[119],"therapies.":[120],"Emphasis":[121],"placed":[123],"on":[124],"their":[125],"potential,":[127],"current":[128],"limitations,":[129],"challenges":[132],"achieving":[134],"sustained":[137],"Finally,":[140],"future":[141],"perspectives":[142],"are":[143],"discussed,":[144],"highlighting":[145],"need":[147],"for":[148],"more":[149,175],"targeted":[150],"durable":[152],"approaches":[154],"that":[155],"address":[156],"multifaceted":[158],"neovascularization.":[163],"A":[164],"deeper":[165],"facilitate":[171],"treatments":[177],"ultimately":[179],"contribute":[180],"improved":[182],"transparency":[184],"outcomes.":[187]},"counts_by_year":[],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2026-11-04T00:00:00"}
