{"id":"https://openalex.org/W7225163473","doi":"https://doi.org/10.1007/s12229-026-09342-1","title":"Dopamine in Plants and Animals: Biosynthesis, Physiological Roles, and Therapeutic Potential","display_name":"Dopamine in Plants and Animals: Biosynthesis, Physiological Roles, and Therapeutic Potential","publication_year":2026,"publication_date":"2026-11-03","ids":{"openalex":"https://openalex.org/W7225163473","doi":"https://doi.org/10.1007/s12229-026-09342-1"},"language":"en","primary_location":{"id":"doi:10.1007/s12229-026-09342-1","doi":"https://doi.org/10.1007/s12229-026-09342-1","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s12229-026-09342-1","pdf_url":"https://link.springer.com/content/pdf/10.1007/s12229-026-09342-1.pdf","source":{"id":"https://openalex.org/S285199","display_name":"The Botanical Review","issn_l":"0006-8101","issn":["0006-8101","1874-9372"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Botanical Review","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://link.springer.com/content/pdf/10.1007/s12229-026-09342-1.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5114660074","display_name":"Nour M. Elbana","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I21376657","display_name":"Tanta University","ror":"https://ror.org/016jp5b92","country_code":"EG","type":"education","lineage":["https://openalex.org/I21376657"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Nour M. Elbana","raw_affiliation_strings":["Botany Department, Faculty of Science, Tanta University, Tanta, 31527, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Botany Department, Faculty of Science, Tanta University, Tanta, 31527, Egypt","institution_ids":["https://openalex.org/I21376657"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160555556","display_name":"Samar Elmatarawy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I21376657","display_name":"Tanta University","ror":"https://ror.org/016jp5b92","country_code":"EG","type":"education","lineage":["https://openalex.org/I21376657"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Samar Elmatarawy","raw_affiliation_strings":["Botany Department, Faculty of Science, Tanta University, Tanta, 31527, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Botany Department, Faculty of Science, Tanta University, Tanta, 31527, Egypt","institution_ids":["https://openalex.org/I21376657"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017553722","display_name":"Khalil M. Saad\u2010Allah","orcid":"https://orcid.org/0000-0003-1679-5656","observed_orcids":["https://orcid.org/0000-0003-1679-5656"]},"institutions":[{"id":"https://openalex.org/I21376657","display_name":"Tanta University","ror":"https://ror.org/016jp5b92","country_code":"EG","type":"education","lineage":["https://openalex.org/I21376657"]}],"countries":["EG"],"is_corresponding":true,"raw_author_name":"Khalil M. Saad-Allah","raw_affiliation_strings":["Botany Department, Faculty of Science, Tanta University, Tanta, 31527, Egypt"],"raw_orcid":"https://orcid.org/0000-0003-1679-5656","affiliations":[{"raw_affiliation_string":"Botany Department, Faculty of Science, Tanta University, Tanta, 31527, Egypt","institution_ids":["https://openalex.org/I21376657"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5160476517","display_name":"Amira M. Hassan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I21376657","display_name":"Tanta University","ror":"https://ror.org/016jp5b92","country_code":"EG","type":"education","lineage":["https://openalex.org/I21376657"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Amira M. Hassan","raw_affiliation_strings":["Botany Department, Faculty of Science, Tanta University, Tanta, 31527, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Botany Department, Faculty of Science, Tanta University, Tanta, 31527, Egypt","institution_ids":["https://openalex.org/I21376657"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5017553722"],"corresponding_institution_ids":["https://openalex.org/I21376657"],"apc_list":{"value":3790,"currency":"USD","value_usd":3790},"apc_paid":{"value":3790,"currency":"USD","value_usd":3790},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.7508658,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11882","display_name":"Plant biochemistry and biosynthesis","score":0.7728999853134155,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11882","display_name":"Plant biochemistry and biosynthesis","score":0.7728999853134155,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11237","display_name":"Plant Gene Expression Analysis","score":0.08330000191926956,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10184","display_name":"Plant Molecular Biology Research","score":0.060600001364946365,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dopamine","display_name":"dopamine","score":0.9319999814033508},{"id":"https://openalex.org/keywords/dopamine-synthesis","display_name":"dopamine synthesis","score":0.765999972820282},{"id":"https://openalex.org/keywords/l-dopa","display_name":"L-DOPA","score":0.9390000104904175},{"id":"https://openalex.org/keywords/tyrosine-metabolism","display_name":"tyrosine metabolism","score":0.718999981880188},{"id":"https://openalex.org/keywords/plant-secondary-metabolites","display_name":"plant secondary metabolites","score":0.9089999794960022},{"id":"https://openalex.org/keywords/plant-stress-adaptation","display_name":"plant stress adaptation","score":0.6710000038146973},{"id":"https://openalex.org/keywords/abiotic-stress-tolerance","display_name":"abiotic stress tolerance","score":0.8040000200271606},{"id":"https://openalex.org/keywords/parkinson-s-disease","display_name":"Parkinson's disease","score":0.7749999761581421},{"id":"https://openalex.org/keywords/schizophrenia","display_name":"schizophrenia","score":0.8009999990463257},{"id":"https://openalex.org/keywords/neurodegenerative-diseases","display_name":"neurodegenerative diseases","score":0.8629999756813049},{"id":"https://openalex.org/keywords/metabolic-engineering","display_name":"metabolic engineering","score":0.8820000290870667},{"id":"https://openalex.org/keywords/genetically-modified-plants","display_name":"transgenic plants","score":0.9649999737739563},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.7710000276565552},{"id":"https://openalex.org/keywords/genetic-engineering-ethics","display_name":"ethics of genetic engineering","score":0.5649999976158142}],"concepts":[{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.864799976348877},{"id":"https://openalex.org/C2776219046","wikidata":"https://www.wikidata.org/wiki/Q162657","display_name":"Neurotransmitter","level":3,"score":0.6305999755859375},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6036999821662903},{"id":"https://openalex.org/C25876315","wikidata":"https://www.wikidata.org/wiki/Q15197465","display_name":"Neurochemical","level":2,"score":0.5259000062942505},{"id":"https://openalex.org/C2910715078","wikidata":"https://www.wikidata.org/wiki/Q162657","display_name":"Neurotransmitter Agents","level":4,"score":0.4681999981403351},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.46209999918937683},{"id":"https://openalex.org/C159167319","wikidata":"https://www.wikidata.org/wiki/Q420766","display_name":"Tyrosine hydroxylase","level":3,"score":0.3944999873638153},{"id":"https://openalex.org/C2775894120","wikidata":"https://www.wikidata.org/wiki/Q271663","display_name":"Catecholamine","level":2,"score":0.35440000891685486},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3449999988079071},{"id":"https://openalex.org/C2776412080","wikidata":"https://www.wikidata.org/wiki/Q7431605","display_name":"Schizophrenia (object-oriented programming)","level":2,"score":0.3303000032901764},{"id":"https://openalex.org/C177606310","wikidata":"https://www.wikidata.org/wiki/Q5674297","display_name":"Adaptability","level":2,"score":0.3255999982357025},{"id":"https://openalex.org/C137183658","wikidata":"https://www.wikidata.org/wiki/Q461076","display_name":"Dopaminergic","level":3,"score":0.31869998574256897},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.30410000681877136},{"id":"https://openalex.org/C89611455","wikidata":"https://www.wikidata.org/wiki/Q6804646","display_name":"Mechanism (biology)","level":2,"score":0.2890999913215637},{"id":"https://openalex.org/C42251903","wikidata":"https://www.wikidata.org/wiki/Q18391002","display_name":"Monoaminergic","level":4,"score":0.28290000557899475},{"id":"https://openalex.org/C102230213","wikidata":"https://www.wikidata.org/wiki/Q430117","display_name":"Transgene","level":3,"score":0.272599995136261},{"id":"https://openalex.org/C2777477808","wikidata":"https://www.wikidata.org/wiki/Q407595","display_name":"Metabolite","level":2,"score":0.25870001316070557},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.2549999952316284}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/s12229-026-09342-1","doi":"https://doi.org/10.1007/s12229-026-09342-1","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s12229-026-09342-1","pdf_url":"https://link.springer.com/content/pdf/10.1007/s12229-026-09342-1.pdf","source":{"id":"https://openalex.org/S285199","display_name":"The Botanical Review","issn_l":"0006-8101","issn":["0006-8101","1874-9372"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Botanical Review","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1007/s12229-026-09342-1","doi":"https://doi.org/10.1007/s12229-026-09342-1","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s12229-026-09342-1","pdf_url":"https://link.springer.com/content/pdf/10.1007/s12229-026-09342-1.pdf","source":{"id":"https://openalex.org/S285199","display_name":"The Botanical Review","issn_l":"0006-8101","issn":["0006-8101","1874-9372"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Botanical Review","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321655","display_name":"Science and Technology Development Fund","ror":"https://ror.org/044vr6g03"},{"id":"https://openalex.org/F4320324798","display_name":"Tanta University","ror":"https://ror.org/016jp5b92"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7225163473.pdf","grobid_xml":"https://content.openalex.org/works/W7225163473.grobid-xml"},"referenced_works_count":205,"referenced_works":["https://openalex.org/W796671511","https://openalex.org/W1545080494","https://openalex.org/W1568778782","https://openalex.org/W1786514222","https://openalex.org/W1963596681","https://openalex.org/W1963861426","https://openalex.org/W1966949437","https://openalex.org/W1966949519","https://openalex.org/W1973717649","https://openalex.org/W1974983455","https://openalex.org/W1981990054","https://openalex.org/W1982045825","https://openalex.org/W1983789042","https://openalex.org/W1984782794","https://openalex.org/W1992324215","https://openalex.org/W1996133279","https://openalex.org/W1997655814","https://openalex.org/W2010505262","https://openalex.org/W2014085028","https://openalex.org/W2015494229","https://openalex.org/W2016908587","https://openalex.org/W2020916930","https://openalex.org/W2021277228","https://openalex.org/W2023921283","https://openalex.org/W2031150004","https://openalex.org/W2034185835","https://openalex.org/W2037679147","https://openalex.org/W2039316426","https://openalex.org/W2043944253","https://openalex.org/W2048982528","https://openalex.org/W2058418706","https://openalex.org/W2060430148","https://openalex.org/W2062065032","https://openalex.org/W2062850767","https://openalex.org/W2067733252","https://openalex.org/W2068175602","https://openalex.org/W2072196622","https://openalex.org/W2076642948","https://openalex.org/W2078842287","https://openalex.org/W2084829207","https://openalex.org/W2099579303","https://openalex.org/W2117045235","https://openalex.org/W2124925125","https://openalex.org/W2127543426","https://openalex.org/W2127627541","https://openalex.org/W2156635671","https://openalex.org/W2160747235","https://openalex.org/W2161511344","https://openalex.org/W2166229011","https://openalex.org/W2170263652","https://openalex.org/W2233625034","https://openalex.org/W2242554444","https://openalex.org/W2273841829","https://openalex.org/W2329648715","https://openalex.org/W2335240697","https://openalex.org/W2409829222","https://openalex.org/W2417327835","https://openalex.org/W2462493218","https://openalex.org/W2496845339","https://openalex.org/W2502088148","https://openalex.org/W2520075163","https://openalex.org/W2530320089","https://openalex.org/W2530533726","https://openalex.org/W2558645692","https://openalex.org/W2573141815","https://openalex.org/W2574013687","https://openalex.org/W2581389709","https://openalex.org/W2588017577","https://openalex.org/W2597492027","https://openalex.org/W2620846900","https://openalex.org/W2673137008","https://openalex.org/W2755633091","https://openalex.org/W2761406608","https://openalex.org/W2772111819","https://openalex.org/W2774729319","https://openalex.org/W2775432281","https://openalex.org/W2784000390","https://openalex.org/W2789369625","https://openalex.org/W2789528636","https://openalex.org/W2792279253","https://openalex.org/W2795241110","https://openalex.org/W2796883330","https://openalex.org/W2797292066","https://openalex.org/W2801363769","https://openalex.org/W2804425318","https://openalex.org/W2806579358","https://openalex.org/W2807135302","https://openalex.org/W2807548455","https://openalex.org/W2807772034","https://openalex.org/W2808102650","https://openalex.org/W2884188211","https://openalex.org/W2885679840","https://openalex.org/W2886036843","https://openalex.org/W2888007380","https://openalex.org/W2890847097","https://openalex.org/W2890970077","https://openalex.org/W2901208536","https://openalex.org/W2901295434","https://openalex.org/W2901489210","https://openalex.org/W2901730600","https://openalex.org/W2905539641","https://openalex.org/W2909672246","https://openalex.org/W2913997818","https://openalex.org/W2921065293","https://openalex.org/W2921722494","https://openalex.org/W2942600280","https://openalex.org/W2945719433","https://openalex.org/W2956221564","https://openalex.org/W2958411204","https://openalex.org/W2972112144","https://openalex.org/W2980466839","https://openalex.org/W2983460331","https://openalex.org/W2985999938","https://openalex.org/W2997108244","https://openalex.org/W2999262081","https://openalex.org/W3000010615","https://openalex.org/W3000398354","https://openalex.org/W3002363560","https://openalex.org/W3021846117","https://openalex.org/W3023223035","https://openalex.org/W3031431980","https://openalex.org/W3031591295","https://openalex.org/W3036821100","https://openalex.org/W3045328797","https://openalex.org/W3092475611","https://openalex.org/W3107584250","https://openalex.org/W3107693414","https://openalex.org/W3118575387","https://openalex.org/W3119006924","https://openalex.org/W3120541480","https://openalex.org/W3127282149","https://openalex.org/W3128158370","https://openalex.org/W3149842496","https://openalex.org/W3154432492","https://openalex.org/W3158099003","https://openalex.org/W3173153861","https://openalex.org/W3197586497","https://openalex.org/W3202379646","https://openalex.org/W3212170262","https://openalex.org/W3214649305","https://openalex.org/W4205222949","https://openalex.org/W4205586680","https://openalex.org/W4210423068","https://openalex.org/W4212954410","https://openalex.org/W4214768268","https://openalex.org/W4280579743","https://openalex.org/W4281721514","https://openalex.org/W4284964353","https://openalex.org/W4285191421","https://openalex.org/W4285222191","https://openalex.org/W4293765847","https://openalex.org/W4293773674","https://openalex.org/W4294617918","https://openalex.org/W4296125444","https://openalex.org/W4296178592","https://openalex.org/W4297521011","https://openalex.org/W4301181037","https://openalex.org/W4307162071","https://openalex.org/W4308323136","https://openalex.org/W4308326606","https://openalex.org/W4308871348","https://openalex.org/W4311825394","https://openalex.org/W4312194938","https://openalex.org/W4318052090","https://openalex.org/W4319880939","https://openalex.org/W4322773012","https://openalex.org/W4323056141","https://openalex.org/W4323318739","https://openalex.org/W4366827339","https://openalex.org/W4378086947","https://openalex.org/W4382653235","https://openalex.org/W4386029183","https://openalex.org/W4390056779","https://openalex.org/W4390327111","https://openalex.org/W4390401685","https://openalex.org/W4391994727","https://openalex.org/W4392003052","https://openalex.org/W4392631447","https://openalex.org/W4392900759","https://openalex.org/W4393387685","https://openalex.org/W4396223249","https://openalex.org/W4397033292","https://openalex.org/W4398762609","https://openalex.org/W4399181083","https://openalex.org/W4401710215","https://openalex.org/W4401727783","https://openalex.org/W4401931124","https://openalex.org/W4402082526","https://openalex.org/W4402554769","https://openalex.org/W4402776909","https://openalex.org/W4402958044","https://openalex.org/W4403004953","https://openalex.org/W4404141385","https://openalex.org/W4405852438","https://openalex.org/W4406264372","https://openalex.org/W4411003058","https://openalex.org/W4413001305","https://openalex.org/W4413117838","https://openalex.org/W4413928755","https://openalex.org/W4414748054","https://openalex.org/W4415351411","https://openalex.org/W4416400579","https://openalex.org/W4417066297","https://openalex.org/W7127883738","https://openalex.org/W7163070815"],"related_works":["https://openalex.org/W4417302854","https://openalex.org/W3118575387","https://openalex.org/W3092475611","https://openalex.org/W3118305282","https://openalex.org/W4413928755","https://openalex.org/W3120541480","https://openalex.org/W7153150849","https://openalex.org/W3107584250","https://openalex.org/W4404493692","https://openalex.org/W1827192400"],"abstract_inverted_index":{"Abstract":[0],"Dopamine":[1,73,102],"is":[2,9,22,74,84,103,116],"a":[3,24,211],"well-known":[4],"neurotransmitter":[5,115],"in":[6,28,31,52,139,157],"animals":[7,53],"that":[8,20,63],"critical":[10,104],"for":[11,76,87,135],"reward,":[12],"motivation,":[13],"and":[14,39,54,79,99,111,123,162,206,216],"movement":[15],"control.":[16],"Recent":[17],"investigations":[18],"demonstrated":[19],"dopamine":[21,48,70,201],"also":[23,85,147],"pivotal":[25],"secondary":[26],"metabolite":[27],"plants,":[29,55,158],"aiding":[30],"the":[32,46,59,65,88,106,129,140,166,174,197],"regulation":[33],"of":[34,67,90,109,113,131,142,168,200],"growth,":[35],"adaptability":[36],"to":[37,58,69,92,105,118,153,209],"stressors,":[38],"defense":[40],"capabilities.":[41],"The":[42,126,145],"review":[43,127,146,175,195],"delves":[44],"into":[45],"various":[47],"biosynthetic":[49],"routes":[50],"identified":[51],"paying":[56],"attention":[57],"key":[60],"enzyme":[61],"systems":[62],"enable":[64],"transformation":[66],"tyrosine":[68],"via":[71],"L-DOPA.":[72],"essential":[75,86],"plant":[77],"development":[78],"nutrient":[80],"uptake,":[81],"but":[82],"it":[83],"adaptation":[89],"plants":[91],"abiotic":[93],"conditions":[94],"such":[95,120,178],"as":[96,121,179],"drought,":[97],"salinity,":[98],"heavy":[100],"metals.":[101],"nervous":[107],"system":[108],"animals,":[110],"dysregulation":[112],"this":[114],"linked":[117],"disorders":[119],"schizophrenia":[122],"Parkinson\u2019s":[124],"disease.":[125],"explores":[128],"potential":[130],"utilizing":[132],"plant-derived":[133],"L-DOPA":[134,155,170,185],"therapeutic":[136],"purposes,":[137],"especially":[138],"treatment":[141],"neurodegenerative":[143],"diseases.":[144],"discusses":[148],"metabolic":[149],"engineering":[150],"approaches":[151],"designed":[152],"boost":[154],"production":[156],"encompassing":[159],"both":[160],"transgenic":[161],"non-transgenic":[163],"methods.":[164],"While":[165],"prospect":[167],"enhanced":[169],"yield":[171],"appears":[172],"promising,":[173],"highlights":[176],"obstacles":[177],"oxidative":[180],"stress":[181],"induced":[182],"by":[183],"elevated":[184],"levels,":[186],"alongside":[187],"ethical":[188],"considerations":[189],"concerning":[190],"genetic":[191],"manipulation.":[192],"This":[193],"thorough":[194],"underscores":[196],"multifaceted":[198],"role":[199],"across":[202],"diverse":[203],"biological":[204],"domains":[205],"its":[207],"capacity":[208],"establish":[210],"connection":[212],"between":[213],"botanical":[214],"research":[215],"human":[217],"health.":[218]},"counts_by_year":[],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2026-11-04T00:00:00"}