{"id":"https://openalex.org/W7225160798","doi":"https://doi.org/10.1093/rap/rkag113.075","title":"P045 Occult large vessel vasculitis in a patient with apparent rheumatoid arthritis","display_name":"P045 Occult large vessel vasculitis in a patient with apparent rheumatoid arthritis","publication_year":2026,"publication_date":"2026-11-01","ids":{"openalex":"https://openalex.org/W7225160798","doi":"https://doi.org/10.1093/rap/rkag113.075"},"language":"en","primary_location":{"id":"doi:10.1093/rap/rkag113.075","doi":"https://doi.org/10.1093/rap/rkag113.075","is_oa":true,"landing_page_url":"https://doi.org/10.1093/rap/rkag113.075","pdf_url":"https://academic.oup.com/rheumap/article-pdf/10/Supplement_1/rkag113.075/72371849/rkag113.075.pdf","source":{"id":"https://openalex.org/S2735938563","display_name":"Rheumatology Advances in Practice","issn_l":"2514-1775","issn":["2514-1775"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","oarl","poland-20","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Rheumatology Advances in Practice","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/rheumap/article-pdf/10/Supplement_1/rkag113.075/72371849/rkag113.075.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5160426818","display_name":"Hugh Larkin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210101239","display_name":"East Suffolk and North Essex NHS Foundation Trust","ror":"https://ror.org/019g08z42","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210101239"]},{"id":"https://openalex.org/I4210160269","display_name":"Ipswich Hospital","ror":"https://ror.org/05m3qrs33","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210101239","https://openalex.org/I4210160269"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Hugh Larkin","raw_affiliation_strings":["East Suffolk and North Essex NHS Foundation Trust , Ipswich,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"East Suffolk and North Essex NHS Foundation Trust , Ipswich,","institution_ids":["https://openalex.org/I4210101239","https://openalex.org/I4210160269"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160543407","display_name":"Suzanne Lane","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210101239","display_name":"East Suffolk and North Essex NHS Foundation Trust","ror":"https://ror.org/019g08z42","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210101239"]},{"id":"https://openalex.org/I4210160269","display_name":"Ipswich Hospital","ror":"https://ror.org/05m3qrs33","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210101239","https://openalex.org/I4210160269"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Suzanne Lane","raw_affiliation_strings":["East Suffolk and North Essex NHS Foundation Trust , Ipswich,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"East Suffolk and North Essex NHS Foundation Trust , Ipswich,","institution_ids":["https://openalex.org/I4210101239","https://openalex.org/I4210160269"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5160415918","display_name":"Haris Raouf","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Haris Raouf","raw_affiliation_strings":["University of Cambridge , Cambridge,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Cambridge , Cambridge,","institution_ids":["https://openalex.org/I241749"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":2255,"currency":"GBP","value_usd":2974},"apc_paid":{"value":2255,"currency":"GBP","value_usd":2974},"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"10","issue":"Supplement_1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10697","display_name":"Vasculitis and related conditions","score":0.9848999977111816,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10697","display_name":"Vasculitis and related conditions","score":0.9848999977111816,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.00930000003427267,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11194","display_name":"Ocular Diseases and Beh\u00e7et\u2019s Syndrome","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/seronegative-rheumatoid-arthritis","display_name":"seronegative rheumatoid arthritis","score":0.8309999704360962},{"id":"https://openalex.org/keywords/seropositive-rheumatoid-arthritis","display_name":"seropositive rheumatoid arthritis","score":0.9769999980926514},{"id":"https://openalex.org/keywords/anti-ccp-antibodies","display_name":"anti-CCP antibodies","score":0.8650000095367432},{"id":"https://openalex.org/keywords/rheumatoid-factor","display_name":"rheumatoid factor","score":0.9789999723434448},{"id":"https://openalex.org/keywords/tocilizumab","display_name":"tocilizumab","score":0.7300000190734863},{"id":"https://openalex.org/keywords/etanercept","display_name":"etanercept","score":0.7609999775886536},{"id":"https://openalex.org/keywords/pet-ct","display_name":"PET/CT","score":0.5559999942779541},{"id":"https://openalex.org/keywords/carotid-artery-involvement","display_name":"carotid artery involvement","score":0.8790000081062317},{"id":"https://openalex.org/keywords/iliac-artery-involvement","display_name":"iliac artery involvement","score":0.8199999928474426},{"id":"https://openalex.org/keywords/aortic-involvement","display_name":"aortic involvement","score":0.6579999923706055},{"id":"https://openalex.org/keywords/differential-diagnosis","display_name":"differential diagnosis","score":0.42500001192092896},{"id":"https://openalex.org/keywords/microcytic-anemia","display_name":"microcytic anemia","score":0.5860000252723694}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9793999791145325},{"id":"https://openalex.org/C2776232647","wikidata":"https://www.wikidata.org/wiki/Q702883","display_name":"Rheumatoid factor","level":3,"score":0.7671999931335449},{"id":"https://openalex.org/C2779383735","wikidata":"https://www.wikidata.org/wiki/Q420035","display_name":"Sulfasalazine","level":4,"score":0.7537000179290771},{"id":"https://openalex.org/C2777575956","wikidata":"https://www.wikidata.org/wiki/Q187255","display_name":"Rheumatoid arthritis","level":2,"score":0.7228000164031982},{"id":"https://openalex.org/C2776260265","wikidata":"https://www.wikidata.org/wiki/Q511097","display_name":"Psoriatic arthritis","level":3,"score":0.5565999746322632},{"id":"https://openalex.org/C2777226972","wikidata":"https://www.wikidata.org/wiki/Q415343","display_name":"Etanercept","level":3,"score":0.5180000066757202},{"id":"https://openalex.org/C2776015282","wikidata":"https://www.wikidata.org/wiki/Q644318","display_name":"Vasculitis","level":3,"score":0.4900999963283539},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.46799999475479126},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.46560001373291016},{"id":"https://openalex.org/C520017518","wikidata":"https://www.wikidata.org/wiki/Q178934","display_name":"Occult","level":3,"score":0.45649999380111694},{"id":"https://openalex.org/C2777077863","wikidata":"https://www.wikidata.org/wiki/Q170990","display_name":"Arthritis","level":2,"score":0.4489000141620636},{"id":"https://openalex.org/C2776164576","wikidata":"https://www.wikidata.org/wiki/Q62736","display_name":"Osteoarthritis","level":3,"score":0.4375},{"id":"https://openalex.org/C2776237595","wikidata":"https://www.wikidata.org/wiki/Q683498","display_name":"Joint pain","level":2,"score":0.43630000948905945},{"id":"https://openalex.org/C2777365958","wikidata":"https://www.wikidata.org/wiki/Q1327700","display_name":"Reactive arthritis","level":3,"score":0.41179999709129333},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.3950999975204468},{"id":"https://openalex.org/C2776821229","wikidata":"https://www.wikidata.org/wiki/Q16965166","display_name":"Inflammatory arthritis","level":3,"score":0.3801000118255615},{"id":"https://openalex.org/C2778143017","wikidata":"https://www.wikidata.org/wiki/Q111208","display_name":"Erythrocyte sedimentation rate","level":2,"score":0.3734999895095825},{"id":"https://openalex.org/C2776715498","wikidata":"https://www.wikidata.org/wiki/Q11426176","display_name":"Prednisolone","level":2,"score":0.36980000138282776},{"id":"https://openalex.org/C2780564577","wikidata":"https://www.wikidata.org/wiki/Q179945","display_name":"Psoriasis","level":2,"score":0.3675999939441681},{"id":"https://openalex.org/C2776661782","wikidata":"https://www.wikidata.org/wiki/Q52848","display_name":"Spondyloarthropathy","level":3,"score":0.3538999855518341},{"id":"https://openalex.org/C45189115","wikidata":"https://www.wikidata.org/wiki/Q502159","display_name":"Serology","level":3,"score":0.3465999960899353},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.337799996137619},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3264000117778778},{"id":"https://openalex.org/C2777482430","wikidata":"https://www.wikidata.org/wiki/Q7168709","display_name":"Peripheral edema","level":3,"score":0.32589998841285706},{"id":"https://openalex.org/C2779721657","wikidata":"https://www.wikidata.org/wiki/Q49970","display_name":"Hyperuricemia","level":3,"score":0.31929999589920044},{"id":"https://openalex.org/C163764329","wikidata":"https://www.wikidata.org/wiki/Q785022","display_name":"Autoantibody","level":3,"score":0.31790000200271606},{"id":"https://openalex.org/C2781195455","wikidata":"https://www.wikidata.org/wiki/Q422766","display_name":"C-reactive protein","level":3,"score":0.31619998812675476},{"id":"https://openalex.org/C2779146052","wikidata":"https://www.wikidata.org/wiki/Q708176","display_name":"Arthropathy","level":4,"score":0.31130000948905945},{"id":"https://openalex.org/C2777840918","wikidata":"https://www.wikidata.org/wiki/Q1753520","display_name":"Rheumatoid nodule","level":3,"score":0.30059999227523804},{"id":"https://openalex.org/C2779036427","wikidata":"https://www.wikidata.org/wiki/Q381899","display_name":"Fibrinogen","level":2,"score":0.2874000072479248},{"id":"https://openalex.org/C198451711","wikidata":"https://www.wikidata.org/wiki/Q327657","display_name":"Rheumatology","level":2,"score":0.2831000089645386},{"id":"https://openalex.org/C544821477","wikidata":"https://www.wikidata.org/wiki/Q718113","display_name":"Weight loss","level":3,"score":0.28189998865127563},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.28119999170303345},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.2687999904155731},{"id":"https://openalex.org/C2779244835","wikidata":"https://www.wikidata.org/wiki/Q538432","display_name":"Synovitis","level":3,"score":0.2644999921321869},{"id":"https://openalex.org/C2909196033","wikidata":"https://www.wikidata.org/wiki/Q559210","display_name":"Morning stiffness","level":4,"score":0.25769999623298645},{"id":"https://openalex.org/C2776804153","wikidata":"https://www.wikidata.org/wiki/Q210420","display_name":"Corticosteroid","level":2,"score":0.25119999051094055}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1093/rap/rkag113.075","doi":"https://doi.org/10.1093/rap/rkag113.075","is_oa":true,"landing_page_url":"https://doi.org/10.1093/rap/rkag113.075","pdf_url":"https://academic.oup.com/rheumap/article-pdf/10/Supplement_1/rkag113.075/72371849/rkag113.075.pdf","source":{"id":"https://openalex.org/S2735938563","display_name":"Rheumatology Advances in Practice","issn_l":"2514-1775","issn":["2514-1775"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","oarl","poland-20","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Rheumatology Advances in Practice","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13728612","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13728612/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Rheumatol Adv Pract","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/rap/rkag113.075","doi":"https://doi.org/10.1093/rap/rkag113.075","is_oa":true,"landing_page_url":"https://doi.org/10.1093/rap/rkag113.075","pdf_url":"https://academic.oup.com/rheumap/article-pdf/10/Supplement_1/rkag113.075/72371849/rkag113.075.pdf","source":{"id":"https://openalex.org/S2735938563","display_name":"Rheumatology Advances in Practice","issn_l":"2514-1775","issn":["2514-1775"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","oarl","poland-20","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Rheumatology Advances in Practice","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9940000176429749}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7225160798.pdf","grobid_xml":"https://content.openalex.org/works/W7225160798.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W7225196654","https://openalex.org/W85134822","https://openalex.org/W2935317088","https://openalex.org/W7160446557","https://openalex.org/W2802116893","https://openalex.org/W1849025721","https://openalex.org/W39883634","https://openalex.org/W4411995523","https://openalex.org/W2975278486","https://openalex.org/W2339729058"],"abstract_inverted_index":{"Abstract":[0],"Introduction":[1],"We":[2],"present":[3],"the":[4,74,106,242,288,318,407,415,488,514],"case":[5,381],"of":[6,160,205,355],"a":[7,124,313,353,442,457,529],"66-year-old":[8],"female":[9],"whose":[10],"clinical":[11,187,495],"picture":[12],"evolved":[13,323],"over":[14,324,366],"two":[15],"decades.":[16],"She":[17,50,87,140,201,271],"initially":[18,142],"presented":[19,99],"with":[20,56,83,102,113,128,138,144,162,212,237,389,426,444,523,559],"asymmetric":[21],"peripheral":[22],"inflammatory":[23,59,103,130,145,155,170,207,280,331,337,378,446,524],"arthritis":[24,208,306,332,428,447,477,484,525],"and":[25,40,43,65,77,92,109,116,135,147,194,217,231,253,265,277,293,307,321,346,391,409,417,474,487,506,537],"was":[26,44,141,173,180,298,312,333,370],"treated":[27,45],"as":[28,46,210,317,360,399,439,456,493,528],"seronegative":[29,169,330],"arthritis.":[30,49,171,178,240,342,358,379,562],"Ten":[31],"years":[32,512],"later,":[33],"she":[34,245],"developed":[35,246,273],"markedly":[36],"elevated":[37,279],"rheumatoid":[38,48,227,239,305,357,427,476,504,561],"factor":[39,228,505],"anti-CCP":[41,133,232,347,507],"antibodies":[42,134,233],"seropositive":[47,238,356],"subsequently":[51,272],"reported":[52],"significant":[53],"weight":[54,255],"loss":[55],"persistently":[57,278],"raised":[58],"markers":[60],"but":[61,339,431],"no":[62],"synovitis.":[63],"Endoscopy":[64],"CT":[66,260],"excluded":[67,269],"malignancy.":[68,270],"PET-CT":[69,282],"demonstrated":[70,283],"increased":[71],"uptake":[72],"in":[73,100,182,424,521,554],"right":[75],"carotid":[76,289],"left":[78],"internal":[79],"iliac":[80,295],"arteries,":[81,290],"consistent":[82,137,236],"large":[84,284,538,556],"vessel":[85,285,422,539,557],"vasculitis.":[86,309],"responded":[88,148],"well":[89],"to":[90,149,158,175,300,302,335,352,364,372,396,405,470,503,531,546],"corticosteroid":[91],"tocilizumab.":[93],"Case":[94],"description":[95],"This":[96,172,311],"patient":[97,443],"first":[98],"2010":[101],"pain":[104],"affecting":[105],"MCP,":[107],"PIP":[108],"DIP":[110],"joints,":[111],"associated":[112],"minimal":[114],"swelling":[115],"morning":[117],"stiffness.":[118],"Investigations":[119],"at":[120],"that":[121,383,392],"time":[122,390],"revealed":[123],"weakly":[125],"positive":[126,225],"ANA,":[127],"normal":[129],"markers,":[131],"negative":[132],"imaging":[136],"osteoarthritis.":[139],"diagnosed":[143],"osteoarthritis":[146],"hydroxychloroquine.":[150],"Over":[151],"subsequent":[152],"years,":[153],"persistent":[154],"symptoms":[156,276,362,400,520],"led":[157,351],"escalation":[159],"therapy":[161],"methotrexate,":[163],"followed":[164],"by":[165],"sulfasalazine":[166],"for":[167,189,226,534],"evolving":[168],"thought":[174],"represent":[176,336],"psoriatic":[177,341],"Etanercept":[179,297],"commenced":[181],"2017,":[183],"producing":[184],"an":[185,328],"excellent":[186],"response":[188],"several":[190],"years.":[191,326],"Between":[192],"2023":[193],"2025,":[195],"her":[196],"disease":[197],"course":[198],"changed":[199],"significantly.":[200],"experienced":[202],"recurrent":[203],"episodes":[204],"acute":[206],"labelled":[209],"gout,":[211],"serum":[213],"urate":[214],"488":[215],"\u00b5mol/L":[216],"CRP":[218],">100":[219],"mg/L.":[220],"Repeat":[221],"serology":[222,322],"became":[223],"strongly":[224],"(403":[229],"IU/mL)":[230],"(317":[234],"U/mL),":[235],"During":[241],"same":[243],"period,":[244],"microcytic":[247],"anaemia,":[248],"pancytopenia,":[249],"declining":[250],"renal":[251],"function":[252],"unintentional":[254],"loss.":[256],"Extensive":[257],"investigations,":[258],"including":[259],"imaging,":[261],"colorectal,":[262],"respiratory,":[263],"haematological":[264],"ENT":[266],"assessment,":[267],"eventually":[268],"polymyalgia":[274],"rheumatica-like":[275],"markers.":[281],"vasculitis":[286,403,423,452,473,558],"involving":[287,414],"thoracic":[291],"aorta":[292,416],"common":[294],"arteries.":[296],"switched":[299],"tocilizumab":[301,466],"treat":[303,471],"both":[304],"large-vessel":[308,472],"Discussion":[310],"sequential":[314],"diagnostic":[315],"challenge":[316],"patient\u2019s":[319,461],"presentation":[320],"fifteen":[325],"Initially,":[327],"undifferentiated":[329],"considered":[334,455],"osteoarthritis,":[338],"later":[340],"The":[343,460],"changing":[344],"RF":[345],"antibody":[348],"status":[349],"then":[350],"diagnosis":[354,489],"However,":[359],"constitutional":[361],"began":[363],"dominate":[365],"improving":[367],"arthralgia,":[368],"it":[369,393],"important":[371,395],"consider":[373],"other":[374],"aetiologies":[375],"beyond":[376],"active":[377,547],"Our":[380],"highlights":[382],"patients\u2019":[384],"diagnoses":[385],"can":[386,467,509,551],"indeed":[387],"change":[388],"is":[394,429,432],"remain":[397],"vigilant":[398],"evolve.":[401],"Rheumatoid":[402],"tends":[404],"favour":[406],"medium":[408],"small":[410],"vessels":[411],"rather":[412,541],"than":[413,542],"its":[418],"major":[419],"branches.":[420],"Large":[421],"patients":[425,522],"described":[430],"not":[433],"frequently":[434],"encountered.":[435],"In":[436],"cases":[437],"such":[438],"this,":[440],"where":[441],"pre-existing":[445],"develops":[448],"prominent":[449],"systemic":[450],"symptoms,":[451],"should":[453,490,526],"be":[454,468,491,552],"potential":[458],"cause.":[459],"outcome":[462],"also":[463],"demonstrates":[464],"how":[465],"used":[469],"concurrent":[475,560],"effectively.":[478],"Key":[479],"learning":[480],"points":[481],"1.":[482],"Inflammatory":[483],"may":[485],"change,":[486],"reconsidered":[492],"new":[494],"features":[496],"or":[497],"investigation":[498],"abnormalities":[499],"emerge.":[500],"2.":[501],"Seroconversion":[502],"positivity":[508],"develop":[510],"many":[511],"after":[513],"original":[515],"symptom":[516],"onset.":[517],"3.":[518],"Constitutional":[519],"act":[527],"stimulus":[530],"investigate":[532],"thoroughly":[533],"infection,":[535],"malignancy":[536],"vasculitis,":[540],"simply":[543],"being":[544],"attributed":[545],"disease.":[548],"4.":[549],"Tocilizumab":[550],"effective":[553],"treating":[555]},"counts_by_year":[],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2026-11-04T00:00:00"}