{"id":"https://openalex.org/W7225155157","doi":"https://doi.org/10.1002/epi.70565","title":"Late electroencephalographic seizure\u2010risk findings and restricted diffusion on magnetic resonance imaging as seizure\u2010burden markers associated with neurological deficits after status epilepticus in a remote or chronic cohort","display_name":"Late electroencephalographic seizure\u2010risk findings and restricted diffusion on magnetic resonance imaging as seizure\u2010burden markers associated with neurological deficits after status epilepticus in a remote or chronic cohort","publication_year":2026,"publication_date":"2026-11-03","ids":{"openalex":"https://openalex.org/W7225155157","doi":"https://doi.org/10.1002/epi.70565","pmid":"https://pubmed.ncbi.nlm.nih.gov/42975879"},"language":"en","primary_location":{"id":"doi:10.1002/epi.70565","doi":"https://doi.org/10.1002/epi.70565","is_oa":true,"landing_page_url":"https://doi.org/10.1002/epi.70565","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/epi.70565","source":{"id":"https://openalex.org/S203153751","display_name":"Epilepsia","issn_l":"0013-9580","issn":["0013-9580","1528-1157","1528-1167"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Epilepsia","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/epi.70565","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5025087538","display_name":"Narumi Ohno","orcid":"https://orcid.org/0009-0006-6218-0328","observed_orcids":["https://orcid.org/0009-0006-6218-0328"]},"institutions":[{"id":"https://openalex.org/I113306721","display_name":"Hiroshima University","ror":"https://ror.org/03t78wx29","country_code":"JP","type":"education","lineage":["https://openalex.org/I113306721"]},{"id":"https://openalex.org/I4210125056","display_name":"Hiroshima University Hospital","ror":"https://ror.org/038dg9e86","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210125056"]},{"id":"https://openalex.org/I4405283031","display_name":"Hiroshima City Hiroshima Citizens Hospital","ror":"https://ror.org/00wk7rn29","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405283031"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Narumi Ohno","raw_affiliation_strings":["Department of Clinical Neuroscience and Therapeutics Hiroshima University, Graduate School of Biomedical and Health Sciences  Hiroshima Japan","Department of Neurology Hiroshima City Hiroshima Citizens Hospital  Hiroshima Japan","Epilepsy Center Hiroshima University Hospital  Hiroshima Japan"],"raw_orcid":"https://orcid.org/0009-0006-6218-0328","affiliations":[{"raw_affiliation_string":"Department of Clinical Neuroscience and Therapeutics Hiroshima University, Graduate School of Biomedical and Health Sciences  Hiroshima Japan","institution_ids":["https://openalex.org/I113306721"]},{"raw_affiliation_string":"Department of Neurology Hiroshima City Hiroshima Citizens Hospital  Hiroshima Japan","institution_ids":["https://openalex.org/I4405283031"]},{"raw_affiliation_string":"Epilepsy Center Hiroshima University Hospital  Hiroshima Japan","institution_ids":["https://openalex.org/I4210125056"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021591308","display_name":"Shuichiro Neshige","orcid":"https://orcid.org/0000-0002-5879-155X","observed_orcids":["https://orcid.org/0000-0002-5879-155X"]},"institutions":[{"id":"https://openalex.org/I113306721","display_name":"Hiroshima University","ror":"https://ror.org/03t78wx29","country_code":"JP","type":"education","lineage":["https://openalex.org/I113306721"]},{"id":"https://openalex.org/I4210125056","display_name":"Hiroshima University Hospital","ror":"https://ror.org/038dg9e86","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210125056"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Shuichiro Neshige","raw_affiliation_strings":["Department of Clinical Neuroscience and Therapeutics Hiroshima University, Graduate School of Biomedical and Health Sciences  Hiroshima Japan","Epilepsy Center Hiroshima University Hospital  Hiroshima Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Neuroscience and Therapeutics Hiroshima University, Graduate School of Biomedical and Health Sciences  Hiroshima Japan","institution_ids":["https://openalex.org/I113306721"]},{"raw_affiliation_string":"Epilepsy Center Hiroshima University Hospital  Hiroshima Japan","institution_ids":["https://openalex.org/I4210125056"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072536476","display_name":"\u5ca1\u7530 \u8389\u6b69","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I113306721","display_name":"Hiroshima University","ror":"https://ror.org/03t78wx29","country_code":"JP","type":"education","lineage":["https://openalex.org/I113306721"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Riho Okada","raw_affiliation_strings":["Department of Clinical Neuroscience and Therapeutics Hiroshima University, Graduate School of Biomedical and Health Sciences  Hiroshima Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Neuroscience and Therapeutics Hiroshima University, Graduate School of Biomedical and Health Sciences  Hiroshima Japan","institution_ids":["https://openalex.org/I113306721"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160471614","display_name":"Takafumi Abe","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I113306721","display_name":"Hiroshima University","ror":"https://ror.org/03t78wx29","country_code":"JP","type":"education","lineage":["https://openalex.org/I113306721"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takafumi Abe","raw_affiliation_strings":["Department of Clinical Neuroscience and Therapeutics Hiroshima University, Graduate School of Biomedical and Health Sciences  Hiroshima Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Neuroscience and Therapeutics Hiroshima University, Graduate School of Biomedical and Health Sciences  Hiroshima Japan","institution_ids":["https://openalex.org/I113306721"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160432940","display_name":"Keito Ishihara","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I113306721","display_name":"Hiroshima University","ror":"https://ror.org/03t78wx29","country_code":"JP","type":"education","lineage":["https://openalex.org/I113306721"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Keito Ishihara","raw_affiliation_strings":["Department of Clinical Neuroscience and Therapeutics Hiroshima University, Graduate School of Biomedical and Health Sciences  Hiroshima Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Neuroscience and Therapeutics Hiroshima University, Graduate School of Biomedical and Health Sciences  Hiroshima Japan","institution_ids":["https://openalex.org/I113306721"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076733785","display_name":"Megumi Nonaka","orcid":"https://orcid.org/0000-0002-2193-3083","observed_orcids":["https://orcid.org/0000-0002-2193-3083"]},"institutions":[{"id":"https://openalex.org/I113306721","display_name":"Hiroshima University","ror":"https://ror.org/03t78wx29","country_code":"JP","type":"education","lineage":["https://openalex.org/I113306721"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Megumi Nonaka","raw_affiliation_strings":["Department of Clinical Neuroscience and Therapeutics Hiroshima University, Graduate School of Biomedical and Health Sciences  Hiroshima Japan"],"raw_orcid":"https://orcid.org/0000-0002-2193-3083","affiliations":[{"raw_affiliation_string":"Department of Clinical Neuroscience and Therapeutics Hiroshima University, Graduate School of Biomedical and Health Sciences  Hiroshima Japan","institution_ids":["https://openalex.org/I113306721"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051140653","display_name":"Haruka Ishibashi","orcid":"https://orcid.org/0000-0002-5428-5350","observed_orcids":["https://orcid.org/0000-0002-5428-5350"]},"institutions":[{"id":"https://openalex.org/I113306721","display_name":"Hiroshima University","ror":"https://ror.org/03t78wx29","country_code":"JP","type":"education","lineage":["https://openalex.org/I113306721"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Haruka Ishibashi","raw_affiliation_strings":["Department of Clinical Neuroscience and Therapeutics Hiroshima University, Graduate School of Biomedical and Health Sciences  Hiroshima Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Neuroscience and Therapeutics Hiroshima University, Graduate School of Biomedical and Health Sciences  Hiroshima Japan","institution_ids":["https://openalex.org/I113306721"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047494394","display_name":"Megumi Toko","orcid":"https://orcid.org/0000-0001-9643-6041","observed_orcids":["https://orcid.org/0000-0001-9643-6041"]},"institutions":[{"id":"https://openalex.org/I113306721","display_name":"Hiroshima University","ror":"https://ror.org/03t78wx29","country_code":"JP","type":"education","lineage":["https://openalex.org/I113306721"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Megumi Toko","raw_affiliation_strings":["Department of Clinical Neuroscience and Therapeutics Hiroshima University, Graduate School of Biomedical and Health Sciences  Hiroshima Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Neuroscience and Therapeutics Hiroshima University, Graduate School of Biomedical and Health Sciences  Hiroshima Japan","institution_ids":["https://openalex.org/I113306721"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019463422","display_name":"Takeo Shishido","orcid":"https://orcid.org/0000-0002-3927-803X","observed_orcids":["https://orcid.org/0000-0002-3927-803X"]},"institutions":[{"id":"https://openalex.org/I113306721","display_name":"Hiroshima University","ror":"https://ror.org/03t78wx29","country_code":"JP","type":"education","lineage":["https://openalex.org/I113306721"]},{"id":"https://openalex.org/I4210104416","display_name":"Hiroshima City Asa Citizens Hospital","ror":"https://ror.org/01hkncq81","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210104416","https://openalex.org/I4405283728"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takeo Shishido","raw_affiliation_strings":["Department of Clinical Neuroscience and Therapeutics Hiroshima University, Graduate School of Biomedical and Health Sciences  Hiroshima Japan","Department of Neurology Hiroshima City North Medical Center Asa Citizens Hospital  Hiroshima Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Neuroscience and Therapeutics Hiroshima University, Graduate School of Biomedical and Health Sciences  Hiroshima Japan","institution_ids":["https://openalex.org/I113306721"]},{"raw_affiliation_string":"Department of Neurology Hiroshima City North Medical Center Asa Citizens Hospital  Hiroshima Japan","institution_ids":["https://openalex.org/I4210104416"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035281439","display_name":"Dai Agari","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405283031","display_name":"Hiroshima City Hiroshima Citizens Hospital","ror":"https://ror.org/00wk7rn29","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405283031"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Dai Agari","raw_affiliation_strings":["Department of Neurology Hiroshima City Hiroshima Citizens Hospital  Hiroshima Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology Hiroshima City Hiroshima Citizens Hospital  Hiroshima Japan","institution_ids":["https://openalex.org/I4405283031"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073764203","display_name":"Yu Yamazaki","orcid":"https://orcid.org/0000-0002-0806-4960","observed_orcids":["https://orcid.org/0000-0002-0806-4960"]},"institutions":[{"id":"https://openalex.org/I113306721","display_name":"Hiroshima University","ror":"https://ror.org/03t78wx29","country_code":"JP","type":"education","lineage":["https://openalex.org/I113306721"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yu Yamazaki","raw_affiliation_strings":["Department of Clinical Neuroscience and Therapeutics Hiroshima University, Graduate School of Biomedical and Health Sciences  Hiroshima Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Neuroscience and Therapeutics Hiroshima University, Graduate School of Biomedical and Health Sciences  Hiroshima Japan","institution_ids":["https://openalex.org/I113306721"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113977319","display_name":"Koji Iida","orcid":"https://orcid.org/0000-0002-6234-1236","observed_orcids":["https://orcid.org/0000-0002-6234-1236"]},"institutions":[{"id":"https://openalex.org/I4210125056","display_name":"Hiroshima University Hospital","ror":"https://ror.org/038dg9e86","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210125056"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Koji Iida","raw_affiliation_strings":["Epilepsy Center Hiroshima University Hospital  Hiroshima Japan"],"raw_orcid":"https://orcid.org/0000-0002-6234-1236","affiliations":[{"raw_affiliation_string":"Epilepsy Center Hiroshima University Hospital  Hiroshima Japan","institution_ids":["https://openalex.org/I4210125056"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5039655833","display_name":"Hirofumi Maruyama","orcid":"https://orcid.org/0000-0001-7613-8717","observed_orcids":["https://orcid.org/0000-0001-7613-8717"]},"institutions":[{"id":"https://openalex.org/I113306721","display_name":"Hiroshima University","ror":"https://ror.org/03t78wx29","country_code":"JP","type":"education","lineage":["https://openalex.org/I113306721"]},{"id":"https://openalex.org/I4210125056","display_name":"Hiroshima University Hospital","ror":"https://ror.org/038dg9e86","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210125056"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hirofumi Maruyama","raw_affiliation_strings":["Department of Clinical Neuroscience and Therapeutics Hiroshima University, Graduate School of Biomedical and Health Sciences  Hiroshima Japan","Epilepsy Center Hiroshima University Hospital  Hiroshima Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Neuroscience and Therapeutics Hiroshima University, Graduate School of Biomedical and Health Sciences  Hiroshima Japan","institution_ids":["https://openalex.org/I113306721"]},{"raw_affiliation_string":"Epilepsy Center Hiroshima University Hospital  Hiroshima Japan","institution_ids":["https://openalex.org/I4210125056"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5021591308"],"corresponding_institution_ids":["https://openalex.org/I113306721","https://openalex.org/I4210125056"],"apc_list":{"value":4360,"currency":"USD","value_usd":4360},"apc_paid":{"value":4360,"currency":"USD","value_usd":4360},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.8560818,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10094","display_name":"Epilepsy research and treatment","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10094","display_name":"Epilepsy research and treatment","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13966","display_name":"Neurological and metabolic disorders","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13201","display_name":"Infectious Encephalopathies and Encephalitis","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/status-epilepticus","display_name":"status epilepticus","score":0.9990000128746033},{"id":"https://openalex.org/keywords/restricted-diffusion","display_name":"restricted diffusion","score":0.9340000152587891},{"id":"https://openalex.org/keywords/apparent-diffusion-coefficient","display_name":"apparent diffusion coefficient","score":0.8830000162124634},{"id":"https://openalex.org/keywords/focal-neurological-deficits","display_name":"focal neurological deficits","score":0.8069999814033508},{"id":"https://openalex.org/keywords/neurological-deterioration","display_name":"neurological deterioration","score":0.8069999814033508},{"id":"https://openalex.org/keywords/seizure-burden","display_name":"seizure burden","score":0.6140000224113464},{"id":"https://openalex.org/keywords/focal-brain-injury","display_name":"focal brain injury","score":0.6470000147819519},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.7519999742507935},{"id":"https://openalex.org/keywords/seizure-duration","display_name":"seizure duration","score":0.6029999852180481},{"id":"https://openalex.org/keywords/population-aged-65-and-over","display_name":"age over 65","score":0.5559999942779541},{"id":"https://openalex.org/keywords/stupor","display_name":"stupor","score":0.8090000152587891}],"concepts":[{"id":"https://openalex.org/C2777341932","wikidata":"https://www.wikidata.org/wiki/Q980709","display_name":"Status epilepticus","level":3,"score":0.7731000185012817},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7311999797821045},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.5960000157356262},{"id":"https://openalex.org/C146638467","wikidata":"https://www.wikidata.org/wiki/Q10529587","display_name":"Hyperintensity","level":3,"score":0.5841000080108643},{"id":"https://openalex.org/C2778186239","wikidata":"https://www.wikidata.org/wiki/Q41571","display_name":"Epilepsy","level":2,"score":0.5550000071525574},{"id":"https://openalex.org/C522805319","wikidata":"https://www.wikidata.org/wiki/Q179965","display_name":"Electroencephalography","level":2,"score":0.5378000140190125},{"id":"https://openalex.org/C156957248","wikidata":"https://www.wikidata.org/wiki/Q1862216","display_name":"Odds ratio","level":2,"score":0.5306000113487244},{"id":"https://openalex.org/C149550507","wikidata":"https://www.wikidata.org/wiki/Q899360","display_name":"Diffusion MRI","level":3,"score":0.5216000080108643},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.510200023651123},{"id":"https://openalex.org/C100136789","wikidata":"https://www.wikidata.org/wiki/Q1772448","display_name":"Coma (optics)","level":2,"score":0.48590001463890076},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.4332999885082245},{"id":"https://openalex.org/C2780168130","wikidata":"https://www.wikidata.org/wiki/Q2916167","display_name":"Neurological examination","level":2,"score":0.4169999957084656},{"id":"https://openalex.org/C17624336","wikidata":"https://www.wikidata.org/wiki/Q461644","display_name":"Glasgow Coma Scale","level":2,"score":0.40849998593330383},{"id":"https://openalex.org/C17755696","wikidata":"https://www.wikidata.org/wiki/Q16564780","display_name":"Ictal","level":3,"score":0.3889000117778778},{"id":"https://openalex.org/C70816921","wikidata":"https://www.wikidata.org/wiki/Q258852","display_name":"Effective diffusion coefficient","level":3,"score":0.3840000033378601},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.35440000891685486},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.34310001134872437},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.33340001106262207},{"id":"https://openalex.org/C58693492","wikidata":"https://www.wikidata.org/wiki/Q551875","display_name":"Neuroimaging","level":2,"score":0.32989999651908875},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.32519999146461487},{"id":"https://openalex.org/C2780317758","wikidata":"https://www.wikidata.org/wiki/Q3339235","display_name":"Neurological disorder","level":3,"score":0.3107999861240387},{"id":"https://openalex.org/C2781192897","wikidata":"https://www.wikidata.org/wiki/Q822050","display_name":"White matter","level":3,"score":0.304500013589859},{"id":"https://openalex.org/C2780939311","wikidata":"https://www.wikidata.org/wiki/Q268594","display_name":"Stupor","level":3,"score":0.29660001397132874},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.28929999470710754},{"id":"https://openalex.org/C16568411","wikidata":"https://www.wikidata.org/wiki/Q83042","display_name":"Neurology","level":2,"score":0.2745000123977661},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.27309998869895935},{"id":"https://openalex.org/C2779281540","wikidata":"https://www.wikidata.org/wiki/Q5062122","display_name":"Central nervous system disease","level":2,"score":0.27129998803138733},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.260699987411499},{"id":"https://openalex.org/C2779889316","wikidata":"https://www.wikidata.org/wiki/Q642836","display_name":"Neuroradiology","level":3,"score":0.25290000438690186}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1002/epi.70565","doi":"https://doi.org/10.1002/epi.70565","is_oa":true,"landing_page_url":"https://doi.org/10.1002/epi.70565","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/epi.70565","source":{"id":"https://openalex.org/S203153751","display_name":"Epilepsia","issn_l":"0013-9580","issn":["0013-9580","1528-1157","1528-1167"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Epilepsia","raw_type":"journal-article"},{"id":"pmid:42975879","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42975879","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Epilepsia","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1002/epi.70565","doi":"https://doi.org/10.1002/epi.70565","is_oa":true,"landing_page_url":"https://doi.org/10.1002/epi.70565","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/epi.70565","source":{"id":"https://openalex.org/S203153751","display_name":"Epilepsia","issn_l":"0013-9580","issn":["0013-9580","1528-1157","1528-1167"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Epilepsia","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7225155157.pdf","grobid_xml":"https://content.openalex.org/works/W7225155157.grobid-xml"},"referenced_works_count":27,"referenced_works":["https://openalex.org/W1856414226","https://openalex.org/W1985820615","https://openalex.org/W2007035168","https://openalex.org/W2131888662","https://openalex.org/W2137129417","https://openalex.org/W2150163312","https://openalex.org/W2396282155","https://openalex.org/W2559782532","https://openalex.org/W2762002773","https://openalex.org/W2805063641","https://openalex.org/W2970419350","https://openalex.org/W2998876539","https://openalex.org/W3121468319","https://openalex.org/W3128479886","https://openalex.org/W3197311149","https://openalex.org/W4223564315","https://openalex.org/W4284666479","https://openalex.org/W4294147598","https://openalex.org/W4310124524","https://openalex.org/W4367550787","https://openalex.org/W4391650802","https://openalex.org/W4401476829","https://openalex.org/W4403828474","https://openalex.org/W4409504289","https://openalex.org/W4411362198","https://openalex.org/W4416449847","https://openalex.org/W4416575003"],"related_works":["https://openalex.org/W2970419350","https://openalex.org/W2528960286","https://openalex.org/W2888027905","https://openalex.org/W3193022013","https://openalex.org/W4391141575","https://openalex.org/W7168282971","https://openalex.org/W4388922635","https://openalex.org/W4294147598","https://openalex.org/W4416575003","https://openalex.org/W2141690234"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"evaluate":[2],"whether":[3],"time-dependent":[4],"electroencephalographic":[5],"(EEG)":[6],"seizure":[7,28,48,136,177,219,286,314,319],"risk":[8],"findings":[9,209,301],"and":[10,71,92,105,118,166,302,321],"restricted":[11,73,221,303],"diffusion":[12,74,84,222,304],"on":[13,58,75,196,210,261],"magnetic":[14],"resonance":[15],"imaging":[16,79],"(MRI)":[17],"are":[18],"associated":[19,183,200,225,266,294,306],"with":[20,81,109,125,133,143,184,201,226,234,267,295,307],"neurological":[21,90,95,159,169,236,269,308],"outcomes":[22,186,203,228],"after":[23,68],"status":[24],"epilepticus":[25],"(SE),":[26],"beyond":[27],"duration.":[29],"METHODS:":[30],"This":[31],"two-center":[32],"observational":[33],"study":[34],"included":[35,101],"consecutive":[36],"SE":[37,69,146],"patients":[38,124,164],"from":[39],"2017":[40],"to":[41],"2025.":[42],"We":[43],"examined":[44],"three":[45,103],"seizure-related":[46],"markers:":[47],"duration":[49,178,287,315],"\u2265":[50,56,179,194,259,288],"30":[51,180,289],"min,":[52],"a":[53,59],"2HELPS2B":[54,192,257],"score":[55,193,258],"2":[57,195,260],"late":[60,197,262],"EEG":[61,198,212,263],"(performed":[62],"the":[63,102,139,153,188,239,272],"following":[64],"day":[65],"or":[66,114,147,155,241,274],"later":[67],"onset),":[70],"SE-related":[72],"MRI":[76],"(peri-ictal":[77],"diffusion-weighted":[78],"hyperintensity":[80],"reduced":[82],"apparent":[83],"coefficient":[85],"values).":[86],"Outcomes":[87],"were":[88,213,305],"overall":[89,140,189],"worsening":[91,160],"SE-attributable":[93,167],"focal":[94,150,168,235,268,322],"deficits":[96,170,237,270],"at":[97,116],"discharge.":[98],"Multivariable":[99],"models":[100,217],"markers":[104,311],"age>":[106],"65":[107],"years,":[108],"further":[110],"adjustment":[111],"for":[112],"stupor":[113],"coma":[115],"admission":[117],"third-line":[119],"therapy.":[120],"RESULTS:":[121],"Of":[122],"440":[123],"suspected":[126],"SE,":[127],"297":[128],"had":[129],"confirmed":[130],"SE;":[131],"221":[132],"an":[134],"identified":[135],"focus":[137],"formed":[138,152],"cohort;":[141],"127":[142],"remote":[144,154,240,273],"symptomatic":[145],"preexisting":[148],"chronic":[149,156,242,275],"epilepsy":[151],"cohort.":[157,190],"Overall":[158],"occurred":[161],"in":[162,171,187,204,229,238,271,316],"96":[163],"(43.4%)":[165],"68":[172],"(30.8%).":[173],"In":[174,215],"univariable":[175],"analyses,":[176],"min":[181,290],"was":[182,199,223,264,291],"both":[185,202,205,227,230],"A":[191,256],"cohorts,":[206,231],"whereas":[207,285],"high-risk":[208],"early":[211],"not.":[214],"multivariable":[216],"including":[218],"duration,":[220],"independently":[224,265,293],"most":[232],"strongly":[233],"cohort":[243,276],"(adjusted":[244,277],"odds":[245],"ratio":[246],"[OR]":[247],"=":[248,254,279,283],"28.59,":[249],"95%":[250,281],"confidence":[251],"interval":[252],"[CI]":[253],"7.23-154.99).":[255],"OR":[278],"4.26,":[280],"CI":[282],"1.35-14.24),":[284],"not":[292],"either":[296],"outcome.":[297],"SIGNIFICANCE:":[298],"High-risk":[299],"late-EEG":[300],"deficits.":[309],"These":[310],"may":[312],"complement":[313],"estimating":[317],"cumulative":[318],"burden":[320],"brain":[323],"injury.":[324]},"counts_by_year":[],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2026-11-04T00:00:00"}