{"id":"https://openalex.org/W7225152002","doi":"https://doi.org/10.1016/j.parkreldis.2026.108760","title":"Efficacy of inhaled levodopa by age-based subgroups in Parkinson disease: post hoc analysis of pooled phase III trial data","display_name":"Efficacy of inhaled levodopa by age-based subgroups in Parkinson disease: post hoc analysis of pooled phase III trial data","publication_year":2026,"publication_date":"2026-11-01","ids":{"openalex":"https://openalex.org/W7225152002","doi":"https://doi.org/10.1016/j.parkreldis.2026.108760"},"language":"en","primary_location":{"id":"doi:10.1016/j.parkreldis.2026.108760","doi":"https://doi.org/10.1016/j.parkreldis.2026.108760","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.parkreldis.2026.108760","pdf_url":null,"source":{"id":"https://openalex.org/S147691530","display_name":"Parkinsonism & Related Disorders","issn_l":"1353-8020","issn":["1353-8020","1873-5126"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Parkinsonism & Related Disorders","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5044107842","display_name":"Astrid Scheschonka","orcid":"https://orcid.org/0000-0003-4745-0853","observed_orcids":["https://orcid.org/0000-0003-4745-0853"]},"institutions":[{"id":"https://openalex.org/I4210113494","display_name":"Merz (Germany)","ror":"https://ror.org/025f1e779","country_code":"DE","type":"company","lineage":["https://openalex.org/I4210113494"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Astrid Scheschonka","raw_affiliation_strings":["Merz Therapeutics GmbH, Frankfurt, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Merz Therapeutics GmbH, Frankfurt, Germany","institution_ids":["https://openalex.org/I4210113494"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160522642","display_name":"Margaret Ngure","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210113494","display_name":"Merz (Germany)","ror":"https://ror.org/025f1e779","country_code":"DE","type":"company","lineage":["https://openalex.org/I4210113494"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Margaret Ngure","raw_affiliation_strings":["Merz Therapeutics GmbH, Frankfurt, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Merz Therapeutics GmbH, Frankfurt, Germany","institution_ids":["https://openalex.org/I4210113494"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5122165090","display_name":"Carmen Walter","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210113494","display_name":"Merz (Germany)","ror":"https://ror.org/025f1e779","country_code":"DE","type":"company","lineage":["https://openalex.org/I4210113494"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Carmen Walter","raw_affiliation_strings":["Merz Therapeutics GmbH, Frankfurt, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Merz Therapeutics GmbH, Frankfurt, Germany","institution_ids":["https://openalex.org/I4210113494"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042639662","display_name":"Selena Freisens","orcid":"https://orcid.org/0000-0001-9873-8078","observed_orcids":["https://orcid.org/0000-0001-9873-8078"]},"institutions":[{"id":"https://openalex.org/I4210113494","display_name":"Merz (Germany)","ror":"https://ror.org/025f1e779","country_code":"DE","type":"company","lineage":["https://openalex.org/I4210113494"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Selena Freisens","raw_affiliation_strings":["Merz Therapeutics GmbH, Frankfurt, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Merz Therapeutics GmbH, Frankfurt, Germany","institution_ids":["https://openalex.org/I4210113494"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5023168014","display_name":"Georg Comes","orcid":"https://orcid.org/0000-0002-4690-5425","observed_orcids":["https://orcid.org/0000-0002-4690-5425"]},"institutions":[{"id":"https://openalex.org/I4210113494","display_name":"Merz (Germany)","ror":"https://ror.org/025f1e779","country_code":"DE","type":"company","lineage":["https://openalex.org/I4210113494"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Georg Comes","raw_affiliation_strings":["Merz Therapeutics GmbH, Frankfurt, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Merz Therapeutics GmbH, Frankfurt, Germany","institution_ids":["https://openalex.org/I4210113494"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210113494"],"apc_list":{"value":3460,"currency":"USD","value_usd":3460},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"152","issue":null,"first_page":"108760","last_page":"108760"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10919","display_name":"Deep Brain Stimulation and Movement Disorders","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10863","display_name":"Voice and Speech Disorders","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3616","display_name":"Speech and Hearing"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/parkinson-s-disease","display_name":"Parkinson's disease","score":0.9520000219345093}],"concepts":[{"id":"https://openalex.org/C2780304432","wikidata":"https://www.wikidata.org/wiki/Q300989","display_name":"Levodopa","level":4,"score":0.8091999888420105},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.805400013923645},{"id":"https://openalex.org/C67761136","wikidata":"https://www.wikidata.org/wiki/Q2105849","display_name":"Post-hoc analysis","level":2,"score":0.7642999887466431},{"id":"https://openalex.org/C2992886853","wikidata":"https://www.wikidata.org/wiki/Q18381816","display_name":"Post hoc","level":2,"score":0.6291999816894531},{"id":"https://openalex.org/C2779734285","wikidata":"https://www.wikidata.org/wiki/Q11085","display_name":"Parkinson's disease","level":3,"score":0.6057999730110168},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5909000039100647},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.39329999685287476},{"id":"https://openalex.org/C3017906399","wikidata":"https://www.wikidata.org/wiki/Q48973845","display_name":"Pooled analysis","level":3,"score":0.37869998812675476},{"id":"https://openalex.org/C3018987647","wikidata":"https://www.wikidata.org/wiki/Q3221083","display_name":"Motor symptoms","level":4,"score":0.3718999922275543},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.36039999127388},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.3587000072002411},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.34779998660087585},{"id":"https://openalex.org/C31760486","wikidata":"https://www.wikidata.org/wiki/Q7180990","display_name":"Phases of clinical research","level":3,"score":0.32850000262260437},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.3066999912261963},{"id":"https://openalex.org/C44280652","wikidata":"https://www.wikidata.org/wiki/Q104837","display_name":"Phase (matter)","level":2,"score":0.2538999915122986}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.parkreldis.2026.108760","doi":"https://doi.org/10.1016/j.parkreldis.2026.108760","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.parkreldis.2026.108760","pdf_url":null,"source":{"id":"https://openalex.org/S147691530","display_name":"Parkinsonism & Related Disorders","issn_l":"1353-8020","issn":["1353-8020","1873-5126"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Parkinsonism & Related Disorders","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W7225185321","https://openalex.org/W7225176316","https://openalex.org/W2341405122","https://openalex.org/W2804412694","https://openalex.org/W4288748910","https://openalex.org/W2793888333","https://openalex.org/W7225188696","https://openalex.org/W2400405659","https://openalex.org/W4367302967","https://openalex.org/W4389376433"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2026-11-04T00:00:00"}