{"id":"https://openalex.org/W7225151328","doi":"https://doi.org/10.64898/2026.11.02.763697","title":"Mapping AMPA and NMDA receptors at mouse brain hippocampal synapses by cryo-ET","display_name":"Mapping AMPA and NMDA receptors at mouse brain hippocampal synapses by cryo-ET","publication_year":2026,"publication_date":"2026-11-03","ids":{"openalex":"https://openalex.org/W7225151328","doi":"https://doi.org/10.64898/2026.11.02.763697"},"language":"en","primary_location":{"id":"doi:10.64898/2026.11.02.763697","doi":"https://doi.org/10.64898/2026.11.02.763697","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.11.02.763697","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2026/11/03/2026.11.02.763697.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.biorxiv.org/content/biorxiv/early/2026/11/03/2026.11.02.763697.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034663376","display_name":"Cathy J. Spangler","orcid":"https://orcid.org/0000-0003-2334-3957","observed_orcids":["https://orcid.org/0000-0003-2334-3957"]},"institutions":[{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cathy J Spangler","raw_affiliation_strings":["Oregon Health & Science University;"],"raw_orcid":"https://orcid.org/0000-0003-2334-3957","affiliations":[{"raw_affiliation_string":"Oregon Health & Science University;","institution_ids":["https://openalex.org/I165690674"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103275328","display_name":"Aya Matsui","orcid":"https://orcid.org/0000-0003-4437-8278","observed_orcids":["https://orcid.org/0000-0003-4437-8278"]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]},{"id":"https://openalex.org/I2802707198","display_name":"Vollum Institute","ror":"https://ror.org/054hm6j14","country_code":"US","type":"facility","lineage":["https://openalex.org/I2802707198"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Aya Matsui","raw_affiliation_strings":[". Howard Hughes Medical Institute , Oregon Health & Science University , Portland , OR 97239 USA",". Vollum Institute , Oregon Health & Science University , Portland , OR 97239 , USA"],"raw_orcid":"https://orcid.org/0000-0003-4437-8278","affiliations":[{"raw_affiliation_string":". Howard Hughes Medical Institute , Oregon Health & Science University , Portland , OR 97239 USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I165690674"]},{"raw_affiliation_string":". Vollum Institute , Oregon Health & Science University , Portland , OR 97239 , USA","institution_ids":["https://openalex.org/I165690674","https://openalex.org/I2802707198"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100670373","display_name":"Hoyoung Kim","orcid":"https://orcid.org/0000-0002-1897-4319","observed_orcids":["https://orcid.org/0000-0002-1897-4319"]},"institutions":[{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hoyoung Kim","raw_affiliation_strings":["Oregon Health & Science University;"],"raw_orcid":"https://orcid.org/0000-0002-1897-4319","affiliations":[{"raw_affiliation_string":"Oregon Health & Science University;","institution_ids":["https://openalex.org/I165690674"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5152469613","display_name":"Elizaveta V Shiltseva","orcid":"https://orcid.org/0009-0002-9495-2784","observed_orcids":["https://orcid.org/0009-0002-9495-2784"]},"institutions":[{"id":"https://openalex.org/I166722992","display_name":"University of Massachusetts Chan Medical School","ror":"https://ror.org/0464eyp60","country_code":"US","type":"education","lineage":["https://openalex.org/I166722992"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elizaveta V Shiltseva","raw_affiliation_strings":["University of Massachusetts Chan Medical School;"],"raw_orcid":"https://orcid.org/0009-0002-9495-2784","affiliations":[{"raw_affiliation_string":"University of Massachusetts Chan Medical School;","institution_ids":["https://openalex.org/I166722992"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058704051","display_name":"Gunasekaran Dhandapani","orcid":"https://orcid.org/0000-0002-1402-3620","observed_orcids":["https://orcid.org/0000-0002-1402-3620"]},"institutions":[{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gunasekaran Dhandapani","raw_affiliation_strings":["Oregon Health & Science University;"],"raw_orcid":"https://orcid.org/0000-0002-1402-3620","affiliations":[{"raw_affiliation_string":"Oregon Health & Science University;","institution_ids":["https://openalex.org/I165690674"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022453964","display_name":"Dennis J. Weingarten","orcid":"https://orcid.org/0000-0003-1435-0215","observed_orcids":["https://orcid.org/0000-0003-1435-0215"]},"institutions":[{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dennis J Weingarten","raw_affiliation_strings":["Oregon Health & Science University;"],"raw_orcid":"https://orcid.org/0000-0003-1435-0215","affiliations":[{"raw_affiliation_string":"Oregon Health & Science University;","institution_ids":["https://openalex.org/I165690674"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102923236","display_name":"Rachel A. Arnold","orcid":"https://orcid.org/0009-0005-8744-5946","observed_orcids":["https://orcid.org/0009-0005-8744-5946"]},"institutions":[{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rachel Arnold","raw_affiliation_strings":["Oregon Health & Science University;"],"raw_orcid":"https://orcid.org/0009-0005-8744-5946","affiliations":[{"raw_affiliation_string":"Oregon Health & Science University;","institution_ids":["https://openalex.org/I165690674"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022486326","display_name":"Yui Sugiyama","orcid":"https://orcid.org/0009-0003-8944-0781","observed_orcids":["https://orcid.org/0009-0003-8944-0781"]},"institutions":[{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yui Sugiyama","raw_affiliation_strings":["Oregon Health & Science University;"],"raw_orcid":"https://orcid.org/0009-0003-8944-0781","affiliations":[{"raw_affiliation_string":"Oregon Health & Science University;","institution_ids":["https://openalex.org/I165690674"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053376812","display_name":"Skyler L. Jackman","orcid":"https://orcid.org/0000-0002-6500-3937","observed_orcids":["https://orcid.org/0000-0002-6500-3937"]},"institutions":[{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Skyler Jackman","raw_affiliation_strings":["Oregon Health & Science University;"],"raw_orcid":"https://orcid.org/0000-0002-6500-3937","affiliations":[{"raw_affiliation_string":"Oregon Health & Science University;","institution_ids":["https://openalex.org/I165690674"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037294253","display_name":"Johannes Elferich","orcid":"https://orcid.org/0000-0002-9911-706X","observed_orcids":["https://orcid.org/0000-0002-9911-706X"]},"institutions":[{"id":"https://openalex.org/I166722992","display_name":"University of Massachusetts Chan Medical School","ror":"https://ror.org/0464eyp60","country_code":"US","type":"education","lineage":["https://openalex.org/I166722992"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Johannes Elferich","raw_affiliation_strings":["University of Massachusetts Chan Medical School;"],"raw_orcid":"https://orcid.org/0000-0002-9911-706X","affiliations":[{"raw_affiliation_string":"University of Massachusetts Chan Medical School;","institution_ids":["https://openalex.org/I166722992"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5088125571","display_name":"Eric Gouaux","orcid":"https://orcid.org/0000-0002-8549-2360","observed_orcids":["https://orcid.org/0000-0002-8549-2360"]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]},{"id":"https://openalex.org/I2802707198","display_name":"Vollum Institute","ror":"https://ror.org/054hm6j14","country_code":"US","type":"facility","lineage":["https://openalex.org/I2802707198"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Eric Gouaux","raw_affiliation_strings":[". Howard Hughes Medical Institute , Oregon Health & Science University , Portland , OR 97239 USA",". Vollum Institute , Oregon Health & Science University , Portland , OR 97239 , USA"],"raw_orcid":"https://orcid.org/0000-0002-8549-2360","affiliations":[{"raw_affiliation_string":". Howard Hughes Medical Institute , Oregon Health & Science University , Portland , OR 97239 USA","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I165690674"]},{"raw_affiliation_string":". Vollum Institute , Oregon Health & Science University , Portland , OR 97239 , USA","institution_ids":["https://openalex.org/I165690674","https://openalex.org/I2802707198"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5088125571"],"corresponding_institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I165690674","https://openalex.org/I2802707198"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10857","display_name":"Advanced Electron Microscopy Techniques and Applications","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/1315","display_name":"Structural Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ampa-receptors","display_name":"AMPA receptors","score":0.9950000047683716},{"id":"https://openalex.org/keywords/nmda-receptor","display_name":"NMDA receptor","score":1.0},{"id":"https://openalex.org/keywords/hippocampal-synapses","display_name":"hippocampal synapses","score":0.9810000061988831},{"id":"https://openalex.org/keywords/glutamate-receptors","display_name":"glutamate receptors","score":0.7620000243186951},{"id":"https://openalex.org/keywords/receptor-clustering","display_name":"receptor clustering","score":0.46799999475479126},{"id":"https://openalex.org/keywords/extrasynaptic-receptors","display_name":"extrasynaptic receptors","score":0.8859999775886536},{"id":"https://openalex.org/keywords/synaptic-transmission","display_name":"synaptic transmission","score":0.6600000262260437},{"id":"https://openalex.org/keywords/synaptic-plasticity","display_name":"synaptic plasticity","score":0.824999988079071},{"id":"https://openalex.org/keywords/cryo-electron-tomography","display_name":"cryo-electron tomography","score":0.8100000023841858},{"id":"https://openalex.org/keywords/gold-nanoparticle-labeling","display_name":"gold nanoparticle labeling","score":0.7630000114440918},{"id":"https://openalex.org/keywords/antibody-fragments","display_name":"antibody fragments","score":0.5550000071525574}],"concepts":[{"id":"https://openalex.org/C160268369","wikidata":"https://www.wikidata.org/wiki/Q295251","display_name":"AMPA receptor","level":4,"score":0.8877999782562256},{"id":"https://openalex.org/C154559735","wikidata":"https://www.wikidata.org/wiki/Q7514768","display_name":"Silent synapse","level":5,"score":0.8411999940872192},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6969000101089478},{"id":"https://openalex.org/C73009533","wikidata":"https://www.wikidata.org/wiki/Q1517140","display_name":"Long-term depression","level":5,"score":0.6948999762535095},{"id":"https://openalex.org/C88272193","wikidata":"https://www.wikidata.org/wiki/Q418536","display_name":"Ion channel linked receptors","level":5,"score":0.6834999918937683},{"id":"https://openalex.org/C67018056","wikidata":"https://www.wikidata.org/wiki/Q414896","display_name":"NMDA receptor","level":3,"score":0.6611999869346619},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5141000151634216},{"id":"https://openalex.org/C61174792","wikidata":"https://www.wikidata.org/wiki/Q420510","display_name":"Glutamate receptor","level":3,"score":0.478300005197525},{"id":"https://openalex.org/C200170125","wikidata":"https://www.wikidata.org/wiki/Q969316","display_name":"Neurotransmission","level":3,"score":0.4779999852180481},{"id":"https://openalex.org/C189184402","wikidata":"https://www.wikidata.org/wiki/Q3454536","display_name":"Kainate receptor","level":5,"score":0.4675999879837036},{"id":"https://openalex.org/C148762608","wikidata":"https://www.wikidata.org/wiki/Q3748185","display_name":"Hippocampal formation","level":2,"score":0.44769999384880066},{"id":"https://openalex.org/C197341189","wikidata":"https://www.wikidata.org/wiki/Q863533","display_name":"Postsynaptic potential","level":3,"score":0.4377000033855438},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.4205999970436096},{"id":"https://openalex.org/C187541742","wikidata":"https://www.wikidata.org/wiki/Q4374336","display_name":"Postsynaptic density","level":4,"score":0.3700999915599823},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.35199999809265137},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3418999910354614},{"id":"https://openalex.org/C98229152","wikidata":"https://www.wikidata.org/wiki/Q1551556","display_name":"Synaptic plasticity","level":3,"score":0.31869998574256897},{"id":"https://openalex.org/C2781161787","wikidata":"https://www.wikidata.org/wiki/Q48360","display_name":"Hippocampus","level":2,"score":0.28610000014305115},{"id":"https://openalex.org/C127445978","wikidata":"https://www.wikidata.org/wiki/Q187181","display_name":"Synapse","level":2,"score":0.2502000033855438}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.64898/2026.11.02.763697","doi":"https://doi.org/10.64898/2026.11.02.763697","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.11.02.763697","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2026/11/03/2026.11.02.763697.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.64898/2026.11.02.763697","doi":"https://doi.org/10.64898/2026.11.02.763697","is_oa":true,"landing_page_url":"https://doi.org/10.64898/2026.11.02.763697","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2026/11/03/2026.11.02.763697.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320315474","display_name":"Chan Zuckerberg Initiative","ror":"https://ror.org/02qenvm24"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7225151328.pdf","grobid_xml":"https://content.openalex.org/works/W7225151328.grobid-xml"},"referenced_works_count":13,"referenced_works":["https://openalex.org/W3033005911","https://openalex.org/W3127722007","https://openalex.org/W3208145967","https://openalex.org/W4390782971","https://openalex.org/W4401653410","https://openalex.org/W4402679043","https://openalex.org/W4403579617","https://openalex.org/W6930991061","https://openalex.org/W6969215068","https://openalex.org/W7125980596","https://openalex.org/W7127895053","https://openalex.org/W7132853615","https://openalex.org/W7214000529"],"related_works":["https://openalex.org/W4403579617","https://openalex.org/W4407492327","https://openalex.org/W4407494774","https://openalex.org/W2075695345","https://openalex.org/W2146973655","https://openalex.org/W1933925126","https://openalex.org/W2069124425","https://openalex.org/W2117242960","https://openalex.org/W2160113442","https://openalex.org/W2498957357"],"abstract_inverted_index":{"AMPA":[0,81,93,126,165],"and":[1,31,44,49,55,64,82,107,127,135,138,166,169,180],"NMDA":[2,83,105,109,128,167],"receptors":[3,84,94,106,129,151],"are":[4,95,152],"fundamental":[5],"to":[6,21,74],"synaptic":[7,42,52],"transmission":[8],"through":[9],"the":[10,28,76,123,131,178],"detection":[11],"of":[12,27,33,80,115,125,143,182],"released":[13],"neurotransmitter.":[14],"These":[15],"ion":[16],"channels":[17],"open":[18],"in":[19,25,41,46,88,98],"response":[20],"glutamate":[22,170],"binding,":[23],"resulting":[24],"depolarization":[26],"postsynaptic":[29],"membrane":[30],"influx":[32],"calcium.":[34],"Receptor":[35],"localization":[36,114],"plays":[37],"a":[38],"key":[39],"role":[40],"strength,":[43],"changes":[45],"receptor":[47,60,110],"number":[48],"location":[50],"underpin":[51],"plasticity,":[53],"learning":[54],"memory.":[56],"Here":[57],"we":[58,118,173],"apply":[59],"subunit-specific":[61],"antibody":[62],"fragments":[63],"multiplexed":[65],"gold":[66],"nanoparticle":[67],"conjugates,":[68],"together":[69],"with":[70,103],"cryo-electron":[71],"tomography":[72],"(cryo-ET),":[73],"elucidate":[75],"in-situ":[77],"molecular":[78],"organization":[79],"at":[85,133],"hippocampal":[86,184],"synapses":[87],"adult":[89],"mouse":[90],"brain":[91,183],"tissue.":[92],"predominantly":[96],"found":[97],"densely":[99],"packed":[100],"liquid-like":[101],"clusters,":[102],"interspersed":[104],"adjacent":[108,158],"clusters.":[111],"By":[112,163],"direct":[113],"individual":[116],"receptors,":[117,168],"provide":[119,174],"molecular-resolution":[120],"insight":[121,176],"into":[122,177],"distribution":[124],"across":[130],"synapse,":[132],"peri":[134],"extrasynaptic":[136],"sites,":[137,172],"within":[139],"endocytosed":[140],"vesicles.":[141],"Visualization":[142],"multiple":[144],"presynaptic":[145],"vesicle":[146],"fusion":[147],"events":[148],"suggests":[149],"that":[150],"near,":[153],"but":[154],"not":[155],"always":[156],"directly":[157],"to,":[159],"transmitter":[160],"release":[161,171],"sites.":[162],"mapping":[164],"receptor-resolution":[175],"structure":[179],"function":[181],"synapses.":[185]},"counts_by_year":[],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2026-11-04T00:00:00"}