{"id":"https://openalex.org/W7225118596","doi":"https://doi.org/10.34067/kid.0000001365","title":"Infertility and Quality of Life in Women with CKD","display_name":"Infertility and Quality of Life in Women with CKD","publication_year":2026,"publication_date":"2026-11-02","ids":{"openalex":"https://openalex.org/W7225118596","doi":"https://doi.org/10.34067/kid.0000001365","pmid":"https://pubmed.ncbi.nlm.nih.gov/42970352"},"language":"en","primary_location":{"id":"doi:10.34067/kid.0000001365","doi":"https://doi.org/10.34067/kid.0000001365","is_oa":true,"landing_page_url":"https://doi.org/10.34067/kid.0000001365","pdf_url":null,"source":{"id":"https://openalex.org/S4210217782","display_name":"Kidney360","issn_l":"2641-7650","issn":["2641-7650"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","medline","oarl","poland-20","russia-white-list-4","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Kidney360","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.34067/kid.0000001365","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5008828869","display_name":"Mahua Bhaduri","orcid":"https://orcid.org/0000-0003-4404-768X","observed_orcids":["https://orcid.org/0000-0003-4404-768X","https://orcid.org/0000-0002-9863-9405"]},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]},{"id":"https://openalex.org/I4210113507","display_name":"Fetal Medicine Foundation","ror":"https://ror.org/0261b7b91","country_code":"GB","type":"funder","lineage":["https://openalex.org/I4210113507"]},{"id":"https://openalex.org/I4402554167","display_name":"King's Fertility","ror":"https://ror.org/04xsrsp28","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210111135","https://openalex.org/I4210153400","https://openalex.org/I4402554167"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Mahua Bhaduri","raw_affiliation_strings":["King\u2019s College London, London, SE5 9RS","King\u2019s Fertility, Fetal Medicine Foundation, Denmark Hill, London, SE5 8BB"],"raw_orcid":"https://orcid.org/0000-0002-9863-9405","affiliations":[{"raw_affiliation_string":"King\u2019s College London, London, SE5 9RS","institution_ids":["https://openalex.org/I183935753"]},{"raw_affiliation_string":"King\u2019s Fertility, Fetal Medicine Foundation, Denmark Hill, London, SE5 8BB","institution_ids":["https://openalex.org/I4210113507","https://openalex.org/I4402554167"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032052468","display_name":"Ippokratis Sarris","orcid":"https://orcid.org/0000-0002-8912-5920","observed_orcids":["https://orcid.org/0000-0002-8912-5920"]},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]},{"id":"https://openalex.org/I4210113507","display_name":"Fetal Medicine Foundation","ror":"https://ror.org/0261b7b91","country_code":"GB","type":"funder","lineage":["https://openalex.org/I4210113507"]},{"id":"https://openalex.org/I4402554167","display_name":"King's Fertility","ror":"https://ror.org/04xsrsp28","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210111135","https://openalex.org/I4210153400","https://openalex.org/I4402554167"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ippokratis Sarris","raw_affiliation_strings":["King\u2019s College London, London, SE5 9RS","King\u2019s Fertility, Fetal Medicine Foundation, Denmark Hill, London, SE5 8BB"],"raw_orcid":"https://orcid.org/0000-0002-8912-5920","affiliations":[{"raw_affiliation_string":"King\u2019s College London, London, SE5 9RS","institution_ids":["https://openalex.org/I183935753"]},{"raw_affiliation_string":"King\u2019s Fertility, Fetal Medicine Foundation, Denmark Hill, London, SE5 8BB","institution_ids":["https://openalex.org/I4210113507","https://openalex.org/I4402554167"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107639307","display_name":"Kypros H. Nicolaides","orcid":"https://orcid.org/0000-0003-3515-7684","observed_orcids":["https://orcid.org/0000-0003-3515-7684"]},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]},{"id":"https://openalex.org/I4210113507","display_name":"Fetal Medicine Foundation","ror":"https://ror.org/0261b7b91","country_code":"GB","type":"funder","lineage":["https://openalex.org/I4210113507"]},{"id":"https://openalex.org/I4402554167","display_name":"King's Fertility","ror":"https://ror.org/04xsrsp28","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I4210111135","https://openalex.org/I4210153400","https://openalex.org/I4402554167"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Kypros Nicolaides","raw_affiliation_strings":["King\u2019s College London, London, SE5 9RS","King\u2019s Fertility, Fetal Medicine Foundation, Denmark Hill, London, SE5 8BB"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"King\u2019s College London, London, SE5 9RS","institution_ids":["https://openalex.org/I183935753"]},{"raw_affiliation_string":"King\u2019s Fertility, Fetal Medicine Foundation, Denmark Hill, London, SE5 8BB","institution_ids":["https://openalex.org/I4210113507","https://openalex.org/I4402554167"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5006004010","display_name":"Kate Bramham","orcid":"https://orcid.org/0000-0002-6272-7921","observed_orcids":["https://orcid.org/0000-0002-6272-7921"]},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Kate Bramham","raw_affiliation_strings":["King\u2019s College London, London, SE5 9RS"],"raw_orcid":"https://orcid.org/0000-0002-6272-7921","affiliations":[{"raw_affiliation_string":"King\u2019s College London, London, SE5 9RS","institution_ids":["https://openalex.org/I183935753"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.87817493,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11156","display_name":"Reproductive Health and Technologies","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11156","display_name":"Reproductive Health and Technologies","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10364","display_name":"Reproductive Biology and Fertility","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10390","display_name":"Ovarian function and disorders","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chronic-kidney-disease","display_name":"chronic kidney disease","score":0.9850000143051147},{"id":"https://openalex.org/keywords/infertility","display_name":"infertility","score":0.7879999876022339},{"id":"https://openalex.org/keywords/fertility-related-quality-of-life","display_name":"fertility-related quality of life","score":0.9350000023841858},{"id":"https://openalex.org/keywords/women-s-reproductive-health","display_name":"women's reproductive health","score":0.7269999980926514},{"id":"https://openalex.org/keywords/fertility-counseling","display_name":"fertility counseling","score":0.7760000228881836},{"id":"https://openalex.org/keywords/adjustment-to-chronic-illness","display_name":"adaptation to chronic illness","score":0.8450000286102295},{"id":"https://openalex.org/keywords/socioemotional-well-being","display_name":"social and emotional wellbeing","score":0.4860000014305115}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7949000000953674},{"id":"https://openalex.org/C518429986","wikidata":"https://www.wikidata.org/wiki/Q964401","display_name":"Fertility","level":3,"score":0.7559999823570251},{"id":"https://openalex.org/C2777688143","wikidata":"https://www.wikidata.org/wiki/Q179399","display_name":"Infertility","level":3,"score":0.6413999795913696},{"id":"https://openalex.org/C2779951463","wikidata":"https://www.wikidata.org/wiki/Q7268788","display_name":"Quality of life (healthcare)","level":2,"score":0.5626000165939331},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.4677000045776367},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.3781999945640564},{"id":"https://openalex.org/C121752807","wikidata":"https://www.wikidata.org/wiki/Q1981388","display_name":"Reproductive health","level":3,"score":0.37459999322891235},{"id":"https://openalex.org/C2776210078","wikidata":"https://www.wikidata.org/wiki/Q351870","display_name":"Reproductive medicine","level":3,"score":0.35089999437332153},{"id":"https://openalex.org/C2778653478","wikidata":"https://www.wikidata.org/wiki/Q1054718","display_name":"Kidney disease","level":2,"score":0.3264000117778778},{"id":"https://openalex.org/C2779647306","wikidata":"https://www.wikidata.org/wiki/Q648065","display_name":"Female infertility","level":4,"score":0.3001999855041504},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.3001999855041504},{"id":"https://openalex.org/C147077947","wikidata":"https://www.wikidata.org/wiki/Q1515895","display_name":"Socioeconomic status","level":3,"score":0.2985000014305115},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.2935999929904938},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.2906999886035919},{"id":"https://openalex.org/C74909509","wikidata":"https://www.wikidata.org/wiki/Q10387","display_name":"Gerontology","level":1,"score":0.2867000102996826},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.2526000142097473},{"id":"https://openalex.org/C512399662","wikidata":"https://www.wikidata.org/wiki/Q3505712","display_name":"Family medicine","level":1,"score":0.25040000677108765}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.34067/kid.0000001365","doi":"https://doi.org/10.34067/kid.0000001365","is_oa":true,"landing_page_url":"https://doi.org/10.34067/kid.0000001365","pdf_url":null,"source":{"id":"https://openalex.org/S4210217782","display_name":"Kidney360","issn_l":"2641-7650","issn":["2641-7650"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","medline","oarl","poland-20","russia-white-list-4","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Kidney360","raw_type":"journal-article"},{"id":"pmid:42970352","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42970352","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Kidney360","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.34067/kid.0000001365","doi":"https://doi.org/10.34067/kid.0000001365","is_oa":true,"landing_page_url":"https://doi.org/10.34067/kid.0000001365","pdf_url":null,"source":{"id":"https://openalex.org/S4210217782","display_name":"Kidney360","issn_l":"2641-7650","issn":["2641-7650"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","medline","oarl","poland-20","russia-white-list-4","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Kidney360","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4415426993","https://openalex.org/W4411744110","https://openalex.org/W7217512666","https://openalex.org/W4306839734","https://openalex.org/W4401401993","https://openalex.org/W7033542977","https://openalex.org/W3090770909","https://openalex.org/W3127156290","https://openalex.org/W4249701420","https://openalex.org/W3178057700"],"abstract_inverted_index":{"BACKGROUND:":[0],"Parenthood":[1],"and":[2,18,80,94,115,135,142,150,191,289],"pregnancy":[3],"are":[4,26],"important":[5],"life":[6,24,263],"goals":[7],"for":[8,277,284],"many":[9],"individuals,":[10],"including":[11,75],"those":[12,110,202],"with":[13,31,59,78,101,106,121,129,140,165,181,197,254,279],"CKD.":[14,252],"However,":[15,194],"fertility":[16,108,199,287],"concerns":[17],"their":[19],"impact":[20],"on":[21],"quality":[22,261],"of":[23,66,127,152,229,262],"(QoL)":[25],"often":[27],"overlooked":[28],"in":[29,57,146,163,188,238,251],"people":[30],"complex":[32],"medical":[33],"needs.":[34],"The":[35,216],"Fertility":[36,272],"QoL":[37,47,250],"(FertiQoL)":[38],"questionnaire":[39],"is":[40,243],"a":[41,72,90,274],"validated":[42],"tool":[43],"that":[44],"assesses":[45],"fertility-related":[46,207,249,260],"across":[48],"six":[49],"domains.":[50,193],"This":[51,242],"study":[52,74,91,246],"aimed":[53],"to":[54,62,113,131,205,226,247,269,291],"assess":[55,248],"FertiQoL":[56,87,158],"women":[58,65,77,105,128,164,196,278],"CKD":[60,79,130,141,166,182,214,255],"compared":[61,98],"healthy":[63,82,168],"control":[64],"reproductive":[67,239,292],"age.":[68],"METHODS:":[69],"We":[70],"conducted":[71],"case-control":[73],"102":[76],"84":[81],"controls.":[83],"Participants":[84],"completed":[85],"the":[86,227,244,282],"survey":[88],"during":[89],"visit.":[92],"Domain":[93],"total":[95,156],"scores":[96,187],"were":[97,119,144,223],"between":[99],"groups,":[100],"subgroup":[102],"analyses":[103],"among":[104,195],"prior":[107,198],"treatment,":[109],"actively":[111,203],"trying":[112,204],"conceive,":[114,206],"nulliparous":[116],"women.":[117],"Findings":[118],"reviewed":[120],"an":[122,224],"independent":[123],"expert":[124,217],"patient":[125,218],"group":[126,219],"evaluate":[132],"result":[133],"interpretation":[134],"co-develop":[136],"recommendations.":[137],"RESULTS:":[138],"Women":[139,180,253],"controls":[143,169],"similar":[145],"age,":[147],"BMI,":[148],"parity":[149],"history":[151],"conception":[153],"attempts.":[154],"Median":[155],"scaled":[157],"score":[159],"was":[160],"significantly":[161,185,212],"higher":[162,186],"than":[167,234,264],"(66.2":[170],"[IQR":[171,175],"54.8-77.8]":[172],"vs.":[173],"56.6":[174],"50.5-64.1];":[176],"p":[177],"<":[178],"0.001).":[179],"also":[183],"had":[184],"emotional,":[189],"mind-body":[190],"social":[192],"treatment":[200],"or":[201,258],"QOL":[208],"did":[209],"not":[210],"differ":[211],"by":[213],"status.":[215],"suggested":[220],"these":[221],"findings":[222],"adaptation":[225,268],"demands":[228],"long-term":[230],"ill":[231],"health":[232],"rather":[233],"any":[235],"underlying":[236],"differences":[237],"aspirations.":[240],"CONCLUSIONS:":[241],"first":[245],"reported":[256],"comparable":[257],"better":[259],"controls,":[265],"likely":[266],"reflecting":[267],"chronic":[270],"illness.":[271],"remains":[273],"key":[275],"priority":[276],"CKD,":[280],"highlighting":[281],"need":[283],"proactive,":[285],"multidisciplinary":[286],"counselling":[288],"access":[290],"care.":[293]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-11-03T00:00:00"}