{"id":"https://openalex.org/W7225115014","doi":"https://doi.org/10.3389/fbrio.2026.1947610","title":"The contribution of population genetics to the epidemiological tracing of pathogenic bacteria: the predominant clonal evolution model","display_name":"The contribution of population genetics to the epidemiological tracing of pathogenic bacteria: the predominant clonal evolution model","publication_year":2026,"publication_date":"2026-11-02","ids":{"openalex":"https://openalex.org/W7225115014","doi":"https://doi.org/10.3389/fbrio.2026.1947610"},"language":"en","primary_location":{"id":"doi:10.3389/fbrio.2026.1947610","doi":"https://doi.org/10.3389/fbrio.2026.1947610","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fbrio.2026.1947610","pdf_url":"https://www.frontiersin.org/journals/bacteriology/articles/10.3389/fbrio.2026.1947610/pdf","source":{"id":"https://openalex.org/S4387287361","display_name":"Frontiers in Bacteriology","issn_l":"2813-6144","issn":["2813-6144"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Bacteriology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/journals/bacteriology/articles/10.3389/fbrio.2026.1947610/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5025854394","display_name":"Michel Tibayrenc","orcid":"https://orcid.org/0000-0001-5915-9647","observed_orcids":["https://orcid.org/0000-0001-5915-9647"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I19894307","display_name":"Universit\u00e9 de Montpellier","ror":"https://ror.org/051escj72","country_code":"FR","type":"education","lineage":["https://openalex.org/I19894307"]},{"id":"https://openalex.org/I4210087127","display_name":"Maladies Infectieuses et Vecteurs: \u00c9cologie, G\u00e9n\u00e9tique, \u00c9volution et Contr\u00f4le","ror":"https://ror.org/00357kh21","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I19894307","https://openalex.org/I2802818602","https://openalex.org/I4210087127","https://openalex.org/I4210088668","https://openalex.org/I4210090127","https://openalex.org/I4210107625","https://openalex.org/I4210131494","https://openalex.org/I4210166444"]},{"id":"https://openalex.org/I4210166444","display_name":"Institut de Recherche pour le D\u00e9veloppement","ror":"https://ror.org/05q3vnk25","country_code":"FR","type":"government","lineage":["https://openalex.org/I2802818602","https://openalex.org/I4210090127","https://openalex.org/I4210131494","https://openalex.org/I4210166444"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Michel Tibayrenc","raw_affiliation_strings":["MIVEGEC, Univ. Montpellier, CNRS, IRD"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MIVEGEC, Univ. Montpellier, CNRS, IRD","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I19894307","https://openalex.org/I4210087127","https://openalex.org/I4210166444"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5025854394"],"corresponding_institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I19894307","https://openalex.org/I4210087127","https://openalex.org/I4210166444"],"apc_list":{"value":1950,"currency":"CHF","value_usd":2353},"apc_paid":{"value":1950,"currency":"CHF","value_usd":2353},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.82475024,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"5","issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10012","display_name":"Genetic diversity and population structure","score":0.6133000254631042,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10012","display_name":"Genetic diversity and population structure","score":0.6133000254631042,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11764","display_name":"Evolution and Genetic Dynamics","score":0.1193000003695488,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10195","display_name":"Antimicrobial Resistance in Staphylococcus","score":0.05339999869465828,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/molecular-epidemiology","display_name":"molecular epidemiology","score":0.7609999775886536},{"id":"https://openalex.org/keywords/bacterial-lineages","display_name":"bacterial lineages","score":0.5619999766349792},{"id":"https://openalex.org/keywords/genetic-recombination","display_name":"genetic recombination","score":0.6100000143051147},{"id":"https://openalex.org/keywords/linkage-disequilibrium","display_name":"linkage disequilibrium","score":0.9789999723434448},{"id":"https://openalex.org/keywords/multilocus-genotypes","display_name":"multilocus genotypes","score":0.8629999756813049},{"id":"https://openalex.org/keywords/escherichia-coli","display_name":"Escherichia coli","score":0.8740000128746033},{"id":"https://openalex.org/keywords/mycobacterium-tuberculosis","display_name":"Mycobacterium tuberculosis","score":1.0},{"id":"https://openalex.org/keywords/neisseria-meningitidis","display_name":"Neisseria meningitidis","score":1.0},{"id":"https://openalex.org/keywords/staphylococcus-aureus","display_name":"Staphylococcus aureus","score":0.9959999918937683},{"id":"https://openalex.org/keywords/pathogenic-bacteria","display_name":"pathogenic bacteria","score":0.6129999756813049}],"concepts":[{"id":"https://openalex.org/C11710620","wikidata":"https://www.wikidata.org/wiki/Q680054","display_name":"Microevolution","level":3,"score":0.9448000192642212},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7991999983787537},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.6589999794960022},{"id":"https://openalex.org/C85721925","wikidata":"https://www.wikidata.org/wiki/Q31151","display_name":"Population genetics","level":3,"score":0.5986999869346619},{"id":"https://openalex.org/C167683757","wikidata":"https://www.wikidata.org/wiki/Q5937774","display_name":"Human evolutionary genetics","level":4,"score":0.5410000085830688},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.5231999754905701},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5062000155448914},{"id":"https://openalex.org/C97669555","wikidata":"https://www.wikidata.org/wiki/Q4118435","display_name":"Molecular epidemiology","level":4,"score":0.4821999967098236},{"id":"https://openalex.org/C77434933","wikidata":"https://www.wikidata.org/wiki/Q4043440","display_name":"Multilocus sequence typing","level":4,"score":0.4203000068664551},{"id":"https://openalex.org/C166393388","wikidata":"https://www.wikidata.org/wiki/Q856529","display_name":"Molecular evolution","level":4,"score":0.3465000092983246},{"id":"https://openalex.org/C103316784","wikidata":"https://www.wikidata.org/wiki/Q3634109","display_name":"Microbial genetics","level":3,"score":0.3452000021934509},{"id":"https://openalex.org/C2778458888","wikidata":"https://www.wikidata.org/wiki/Q154625","display_name":"Neisseria meningitidis","level":3,"score":0.32269999384880066},{"id":"https://openalex.org/C2777975735","wikidata":"https://www.wikidata.org/wiki/Q130971","display_name":"Mycobacterium tuberculosis","level":3,"score":0.3156999945640564},{"id":"https://openalex.org/C47042493","wikidata":"https://www.wikidata.org/wiki/Q265799","display_name":"Human genetics","level":3,"score":0.29649999737739563},{"id":"https://openalex.org/C142870003","wikidata":"https://www.wikidata.org/wiki/Q843863","display_name":"Genetic linkage","level":3,"score":0.2964000105857849},{"id":"https://openalex.org/C204315192","wikidata":"https://www.wikidata.org/wiki/Q210506","display_name":"Molecular genetics","level":3,"score":0.2825999855995178},{"id":"https://openalex.org/C171578705","wikidata":"https://www.wikidata.org/wiki/Q5418700","display_name":"Evolutionary dynamics","level":3,"score":0.2800999879837036},{"id":"https://openalex.org/C31266012","wikidata":"https://www.wikidata.org/wiki/Q6554340","display_name":"Linkage (software)","level":3,"score":0.26969999074935913},{"id":"https://openalex.org/C21833749","wikidata":"https://www.wikidata.org/wiki/Q7189431","display_name":"Viral phylodynamics","level":4,"score":0.2639999985694885},{"id":"https://openalex.org/C90132467","wikidata":"https://www.wikidata.org/wiki/Q171184","display_name":"Phylogenetics","level":3,"score":0.260699987411499}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.3389/fbrio.2026.1947610","doi":"https://doi.org/10.3389/fbrio.2026.1947610","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fbrio.2026.1947610","pdf_url":"https://www.frontiersin.org/journals/bacteriology/articles/10.3389/fbrio.2026.1947610/pdf","source":{"id":"https://openalex.org/S4387287361","display_name":"Frontiers in Bacteriology","issn_l":"2813-6144","issn":["2813-6144"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Bacteriology","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:1c86683947ae4eacae80178e490be8c3","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/1c86683947ae4eacae80178e490be8c3","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Bacteriology, Vol 5 (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fbrio.2026.1947610","doi":"https://doi.org/10.3389/fbrio.2026.1947610","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fbrio.2026.1947610","pdf_url":"https://www.frontiersin.org/journals/bacteriology/articles/10.3389/fbrio.2026.1947610/pdf","source":{"id":"https://openalex.org/S4387287361","display_name":"Frontiers in Bacteriology","issn_l":"2813-6144","issn":["2813-6144"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Bacteriology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.504800021648407}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7225115014.pdf","grobid_xml":"https://content.openalex.org/works/W7225115014.grobid-xml"},"referenced_works_count":76,"referenced_works":["https://openalex.org/W2840529","https://openalex.org/W1493529132","https://openalex.org/W1523326647","https://openalex.org/W1561849362","https://openalex.org/W1844831948","https://openalex.org/W1940132199","https://openalex.org/W1980030331","https://openalex.org/W1980248442","https://openalex.org/W1980310800","https://openalex.org/W1981611615","https://openalex.org/W1982447955","https://openalex.org/W1988325090","https://openalex.org/W1989125010","https://openalex.org/W1991894713","https://openalex.org/W1994897898","https://openalex.org/W1997027430","https://openalex.org/W2001750285","https://openalex.org/W2008214584","https://openalex.org/W2012473911","https://openalex.org/W2012994632","https://openalex.org/W2024039353","https://openalex.org/W2027972741","https://openalex.org/W2030966943","https://openalex.org/W2031371942","https://openalex.org/W2032043692","https://openalex.org/W2038699241","https://openalex.org/W2057379122","https://openalex.org/W2069332918","https://openalex.org/W2070561312","https://openalex.org/W2075429769","https://openalex.org/W2077833308","https://openalex.org/W2092252003","https://openalex.org/W2093236649","https://openalex.org/W2098104253","https://openalex.org/W2113449027","https://openalex.org/W2117580564","https://openalex.org/W2129556224","https://openalex.org/W2131961145","https://openalex.org/W2134442823","https://openalex.org/W2135497680","https://openalex.org/W2137360605","https://openalex.org/W2142503351","https://openalex.org/W2142586833","https://openalex.org/W2142927666","https://openalex.org/W2147571700","https://openalex.org/W2161060487","https://openalex.org/W2165471800","https://openalex.org/W2170093840","https://openalex.org/W2288759305","https://openalex.org/W2311395181","https://openalex.org/W2321278271","https://openalex.org/W2340203382","https://openalex.org/W2346352892","https://openalex.org/W2398161452","https://openalex.org/W2520054452","https://openalex.org/W2533232127","https://openalex.org/W2544696205","https://openalex.org/W2655883216","https://openalex.org/W2783758534","https://openalex.org/W2803413725","https://openalex.org/W2884235477","https://openalex.org/W2987841563","https://openalex.org/W3080208929","https://openalex.org/W3118412324","https://openalex.org/W4226050968","https://openalex.org/W4245946037","https://openalex.org/W4401957813","https://openalex.org/W4405325744","https://openalex.org/W4407241105","https://openalex.org/W4408072148","https://openalex.org/W4410194174","https://openalex.org/W4411095947","https://openalex.org/W4411545704","https://openalex.org/W7125422903","https://openalex.org/W7133354522","https://openalex.org/W7160925884"],"related_works":["https://openalex.org/W4400830098","https://openalex.org/W3118412324","https://openalex.org/W2609677605","https://openalex.org/W1128584056","https://openalex.org/W2151886886","https://openalex.org/W2135891608","https://openalex.org/W7099001384","https://openalex.org/W7100807055","https://openalex.org/W2914698827","https://openalex.org/W7096316548"],"abstract_inverted_index":{"This":[0,77],"article":[1],"aims":[2],"to":[3,14,24,56,85,110],"present":[4],"the":[5,15,30,52,57,112],"specific":[6],"contribution":[7],"of":[8,18,59,66,114],"population":[9],"genetics":[10,13],"and":[11,26,49,63,70,145],"evolutionary":[12],"molecular":[16],"tracing":[17,88],"epidemiological":[19,87],"routes":[20],"in":[21,38,47,101],"bacteria":[22],"pathogenic":[23],"humans":[25],"animals.":[27],"More":[28],"specifically,":[29],"\u201cpredominant":[31],"clonal":[32,116],"evolution\u201d":[33],"(PCE)":[34],"model":[35,92],"is":[36,79,99,108],"exposed":[37],"details.":[39],"It":[40],"suggests":[41],"that":[42,96,105],"bacterial":[43],"lineages":[44],"are":[45,132],"stable":[46,125],"space":[48,64],"time,":[50],"from":[51,134],"macroevolutionary":[53],"scale":[54,65],"down":[55],"level":[58],"microevolution":[60],"(a":[61],"time":[62],"a":[67,80],"few":[68,129],"years":[69],"kilometers,":[71],"i.":[72],"e.,":[73],"\u201cmeasurably":[74],"evolving":[75],"pathogens\u201d).":[76],"stability":[78],"\u201csi":[81],"ne":[82],"qua":[83],"non\u201d":[84],"make":[86],"reliable.":[89],"The":[90],"PCE":[91],"does":[93],"not":[94],"state":[95],"genetic":[97],"recombination":[98],"absent":[100],"bacteria,":[102],"but":[103],"merely":[104],"its":[106],"impact":[107],"insufficient":[109],"break":[111],"pattern":[113],"predominant":[115],"evolution":[117],"(clonal":[118],"frame,":[119],"multilocus":[120,126],"bifurcating":[121],"trees,":[122],"linkage":[123],"disequilibrium,":[124],"genotypes).":[127],"A":[128],"illustrative":[130],"examples":[131],"drawn":[133],"major":[135],"species:":[136],"Escherichia":[137],"coli":[138],",":[139,142],"Mycobacterium":[140],"tuberculosis":[141],"Neisseria":[143],"meningitidis":[144],"Staphylococcus":[146],"aureus":[147],".":[148]},"counts_by_year":[],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2026-11-03T00:00:00"}