{"id":"https://openalex.org/W7225113249","doi":"https://doi.org/10.3389/fvets.2026.1867489","title":"Comparative performance of OvaCyte\u2122 Fluke Plus and conventional methods for detecting fluke eggs in domestic ruminants","display_name":"Comparative performance of OvaCyte\u2122 Fluke Plus and conventional methods for detecting fluke eggs in domestic ruminants","publication_year":2026,"publication_date":"2026-11-02","ids":{"openalex":"https://openalex.org/W7225113249","doi":"https://doi.org/10.3389/fvets.2026.1867489"},"language":"en","primary_location":{"id":"doi:10.3389/fvets.2026.1867489","doi":"https://doi.org/10.3389/fvets.2026.1867489","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fvets.2026.1867489","pdf_url":"https://www.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2026.1867489/pdf","source":{"id":"https://openalex.org/S2594976040","display_name":"Frontiers in Veterinary Science","issn_l":"2297-1769","issn":["2297-1769"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Veterinary Science","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2026.1867489/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054740725","display_name":"Nagwa Elghryani","orcid":"https://orcid.org/0000-0002-0843-4431","observed_orcids":["https://orcid.org/0000-0002-0843-4431"]},"institutions":[{"id":"https://openalex.org/I100930933","display_name":"University College Dublin","ror":"https://ror.org/05m7pjf47","country_code":"IE","type":"education","lineage":["https://openalex.org/I100930933"]},{"id":"https://openalex.org/I31439502","display_name":"University of Benghazi","ror":"https://ror.org/03fh7t044","country_code":"LY","type":"education","lineage":["https://openalex.org/I31439502"]}],"countries":["IE","LY"],"is_corresponding":true,"raw_author_name":"Nagwa Elghryani","raw_affiliation_strings":["Department of Biology, Faculty of Arts and Sciences-Gamines, University of Benghazi","Department of Zoology, School of Veterinary Medicine, University College Dublin","Telenostic Ltd"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Faculty of Arts and Sciences-Gamines, University of Benghazi","institution_ids":["https://openalex.org/I31439502"]},{"raw_affiliation_string":"Department of Zoology, School of Veterinary Medicine, University College Dublin","institution_ids":["https://openalex.org/I100930933"]},{"raw_affiliation_string":"Telenostic Ltd","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5120738007","display_name":"Jayanta Bor Gohain","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jayanta Bor Gohain","raw_affiliation_strings":["Telenostic Ltd"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Telenostic Ltd","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065538903","display_name":"Trish McOwan","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Trish McOwan","raw_affiliation_strings":["Telenostic Ltd"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Telenostic Ltd","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007646248","display_name":"Theo D. De Waal","orcid":"https://orcid.org/0000-0002-9657-1857","observed_orcids":["https://orcid.org/0000-0002-9657-1857"]},"institutions":[{"id":"https://openalex.org/I100930933","display_name":"University College Dublin","ror":"https://ror.org/05m7pjf47","country_code":"IE","type":"education","lineage":["https://openalex.org/I100930933"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Theo de Waal","raw_affiliation_strings":["Department of Zoology, School of Veterinary Medicine, University College Dublin"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Zoology, School of Veterinary Medicine, University College Dublin","institution_ids":["https://openalex.org/I100930933"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043876336","display_name":"Giulio Grandi","orcid":"https://orcid.org/0000-0002-9620-1792","observed_orcids":["https://orcid.org/0000-0002-9620-1792"]},"institutions":[{"id":"https://openalex.org/I298625061","display_name":"Swedish University of Agricultural Sciences","ror":"https://ror.org/02yy8x990","country_code":"SE","type":"education","lineage":["https://openalex.org/I298625061"]},{"id":"https://openalex.org/I4405263100","display_name":"Swedish University of Agricultural Sciences, Alnarp","ror":"https://ror.org/02haktn42","country_code":"SE","type":"education","lineage":["https://openalex.org/I298625061","https://openalex.org/I4405263100"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Giulio Grandi","raw_affiliation_strings":["Department of Animal Biosciences (HBIO), Faculty of Veterinary Medicine and Animal Science, Swedish University of Agricultural Sciences"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Animal Biosciences (HBIO), Faculty of Veterinary Medicine and Animal Science, Swedish University of Agricultural Sciences","institution_ids":["https://openalex.org/I298625061","https://openalex.org/I4405263100"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5002734355","display_name":"Johan H\u00f6glund","orcid":"https://orcid.org/0000-0002-1129-6615","observed_orcids":["https://orcid.org/0000-0002-1129-6615"]},"institutions":[{"id":"https://openalex.org/I298625061","display_name":"Swedish University of Agricultural Sciences","ror":"https://ror.org/02yy8x990","country_code":"SE","type":"education","lineage":["https://openalex.org/I298625061"]},{"id":"https://openalex.org/I4405263100","display_name":"Swedish University of Agricultural Sciences, Alnarp","ror":"https://ror.org/02haktn42","country_code":"SE","type":"education","lineage":["https://openalex.org/I298625061","https://openalex.org/I4405263100"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Johan H\u00f6glund","raw_affiliation_strings":["Department of Animal Biosciences (HBIO), Faculty of Veterinary Medicine and Animal Science, Swedish University of Agricultural Sciences"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Animal Biosciences (HBIO), Faculty of Veterinary Medicine and Animal Science, Swedish University of Agricultural Sciences","institution_ids":["https://openalex.org/I298625061","https://openalex.org/I4405263100"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5054740725"],"corresponding_institution_ids":["https://openalex.org/I100930933","https://openalex.org/I31439502"],"apc_list":{"value":3150,"currency":"CHF","value_usd":3801},"apc_paid":{"value":3150,"currency":"CHF","value_usd":3801},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.89001035,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"13","issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11074","display_name":"Helminth infection and control","score":1.0,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11074","display_name":"Helminth infection and control","score":1.0,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10815","display_name":"Parasite Biology and Host Interactions","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2303","display_name":"Ecology"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11086","display_name":"Parasitic Infections and Diagnostics","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fecal-egg-count","display_name":"fecal egg count","score":0.7540000081062317},{"id":"https://openalex.org/keywords/liver-fluke","display_name":"liver fluke","score":0.9380000233650208},{"id":"https://openalex.org/keywords/rumen-fluke","display_name":"rumen fluke","score":0.9909999966621399},{"id":"https://openalex.org/keywords/trematodes","display_name":"trematodes","score":0.6439999938011169},{"id":"https://openalex.org/keywords/sensitivity-and-specificity","display_name":"sensitivity and specificity","score":0.7739999890327454},{"id":"https://openalex.org/keywords/ovine","display_name":"ovine","score":0.4729999899864197},{"id":"https://openalex.org/keywords/cattle","display_name":"cattle","score":0.9929999709129333},{"id":"https://openalex.org/keywords/sedimentation-method","display_name":"sedimentation method","score":0.7490000128746033},{"id":"https://openalex.org/keywords/flotation","display_name":"flotation","score":0.8550000190734863},{"id":"https://openalex.org/keywords/composite-reference-standard","display_name":"composite reference standard","score":0.7519999742507935}],"concepts":[{"id":"https://openalex.org/C13590703","wikidata":"https://www.wikidata.org/wiki/Q1326939","display_name":"Liver fluke","level":3,"score":0.8899999856948853},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7944999933242798},{"id":"https://openalex.org/C70262065","wikidata":"https://www.wikidata.org/wiki/Q427652","display_name":"Rumen","level":3,"score":0.7204999923706055},{"id":"https://openalex.org/C2777856171","wikidata":"https://www.wikidata.org/wiki/Q334149","display_name":"Fasciola hepatica","level":3,"score":0.6326000094413757},{"id":"https://openalex.org/C42972112","wikidata":"https://www.wikidata.org/wiki/Q170201","display_name":"Veterinary medicine","level":1,"score":0.5767999887466431},{"id":"https://openalex.org/C61716771","wikidata":"https://www.wikidata.org/wiki/Q496","display_name":"Feces","level":2,"score":0.5169000029563904},{"id":"https://openalex.org/C2776026265","wikidata":"https://www.wikidata.org/wiki/Q5347942","display_name":"Eggs per gram","level":3,"score":0.42489999532699585},{"id":"https://openalex.org/C3018023364","wikidata":"https://www.wikidata.org/wiki/Q425265","display_name":"Significant difference","level":2,"score":0.39010000228881836},{"id":"https://openalex.org/C165901193","wikidata":"https://www.wikidata.org/wiki/Q3129936","display_name":"Helminths","level":2,"score":0.35589998960494995},{"id":"https://openalex.org/C140793950","wikidata":"https://www.wikidata.org/wiki/Q168091","display_name":"Animal science","level":1,"score":0.34470000863075256},{"id":"https://openalex.org/C2777861111","wikidata":"https://www.wikidata.org/wiki/Q419739","display_name":"Triclabendazole","level":4,"score":0.27309998869895935},{"id":"https://openalex.org/C2778359929","wikidata":"https://www.wikidata.org/wiki/Q207547","display_name":"Trematoda","level":3,"score":0.2718000113964081}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.3389/fvets.2026.1867489","doi":"https://doi.org/10.3389/fvets.2026.1867489","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fvets.2026.1867489","pdf_url":"https://www.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2026.1867489/pdf","source":{"id":"https://openalex.org/S2594976040","display_name":"Frontiers in Veterinary Science","issn_l":"2297-1769","issn":["2297-1769"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Veterinary Science","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:9405a0ff810c41b3b7391ed7ba603177","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/9405a0ff810c41b3b7391ed7ba603177","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Veterinary Science, Vol 13 (2026)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fvets.2026.1867489","doi":"https://doi.org/10.3389/fvets.2026.1867489","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fvets.2026.1867489","pdf_url":"https://www.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2026.1867489/pdf","source":{"id":"https://openalex.org/S2594976040","display_name":"Frontiers in Veterinary Science","issn_l":"2297-1769","issn":["2297-1769"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Veterinary Science","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.5683000087738037},{"id":"https://metadata.un.org/sdg/2","display_name":"Zero hunger","score":0.40450000762939453}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7225113249.pdf","grobid_xml":"https://content.openalex.org/works/W7225113249.grobid-xml"},"referenced_works_count":27,"referenced_works":["https://openalex.org/W1774718455","https://openalex.org/W1975319088","https://openalex.org/W1990821143","https://openalex.org/W2030365642","https://openalex.org/W2044445433","https://openalex.org/W2055559135","https://openalex.org/W2056719597","https://openalex.org/W2084886069","https://openalex.org/W2095437504","https://openalex.org/W2475217173","https://openalex.org/W2484270606","https://openalex.org/W2487094392","https://openalex.org/W2510472194","https://openalex.org/W2545685502","https://openalex.org/W2553689181","https://openalex.org/W2737061126","https://openalex.org/W2770643625","https://openalex.org/W2914363330","https://openalex.org/W2952550096","https://openalex.org/W3045454198","https://openalex.org/W3081858291","https://openalex.org/W4283454934","https://openalex.org/W4304687792","https://openalex.org/W4319600704","https://openalex.org/W4391224797","https://openalex.org/W4391464627","https://openalex.org/W7129207978"],"related_works":["https://openalex.org/W3158733664","https://openalex.org/W7131350905","https://openalex.org/W4376116441","https://openalex.org/W7139950142","https://openalex.org/W7203590928","https://openalex.org/W4385497936","https://openalex.org/W2944112891","https://openalex.org/W2339430934","https://openalex.org/W7129207978","https://openalex.org/W4413117766"],"abstract_inverted_index":{"Background":[0],"Liver":[1],"and":[2,20,35,41,57,60,74,79,90,93,128,147,182,199,231,255,271],"rumen":[3,36,80,145,183,213],"flukes":[4,81,146,184],"are":[5],"major":[6],"trematode":[7],"parasites":[8,159],"of":[9,23,33,110,120,137,267,274],"grazing":[10],"livestock.":[11],"Methods":[12],"This":[13],"study":[14,269],"compared":[15,235],"the":[16,30,45,111,138,154,195,265,268,272],"diagnostic":[17,91],"sensitivity,":[18],"specificity,":[19],"quantitative":[21,229],"recovery":[22,230],"three":[24,112],"faecal":[25,69,133],"egg":[26,174],"count":[27],"techniques":[28],"for":[29,77,126,144,149,157,180,201,212,241,252],"differential":[31],"detection":[32],"liver":[34,78,150,163,181,202,243],"fluke":[37,115,214,244],"eggs":[38],"in":[39,85,264],"ovine":[40],"bovine":[42,132],"faeces:":[43],"(i)":[44],"automated":[46],"AI-based":[47],"OvaCyte\u2122":[48,121,152,170,224],"Fluke":[49,225],"Plus":[50,226],"system,":[51],"(ii)":[52],"a":[53,62,98,205,275],"reference":[54,100,277],"laboratory":[55],"centrifugation":[56],"flotation":[58],"method,":[59],"(iii)":[61],"sedimentation":[63,200],"method.":[64],"Forty-eight":[65],"naturally":[66],"infected":[67],"field":[68,139],"samples,":[70,140],"comprising":[71],"both":[72,158,177],"positive":[73,107],"negative":[75],"samples":[76,103],"were":[82,95,104],"each":[83],"processed":[84],"duplicate":[86],"by":[87],"all":[88],"methods,":[89,239],"sensitivity":[92,156,234],"specificity":[94],"calculated":[96],"using":[97,130],"composite":[99,276],"standard,":[101],"whereby":[102],"classified":[105],"as":[106],"if":[108],"any":[109],"methods":[113,179],"detected":[114,171,211],"eggs.":[116],"The":[117,220,246],"analytical":[118,233],"performance":[119],"was":[122,192,210],"then":[123],"further":[124],"assessed":[125],"reproducibility":[127],"precision":[129],"pooled":[131],"samples.":[134],"Results":[135],"Out":[136],"37":[141],"tested":[142],"positives":[143],"31":[148],"flukes.":[151],"achieved":[153],"highest":[155],"(rumen":[160],"flukes,":[161],"0.95;":[162],"fluke,":[164,203],"0.90)":[165],"with":[166,236],"high":[167],"specificity.":[168],"Quantitatively,":[169],"significantly":[172],"higher":[173,232],"counts":[175],"than":[176],"conventional":[178,237],"(":[185,215],"p":[186,216],"<":[187],"0.001).":[188],"No":[189],"significant":[190,208],"difference":[191,209],"observed":[193],"between":[194],"Reference":[196],"Laboratory":[197],"Method":[198],"whilst":[204],"small":[206],"but":[207],"=":[217],"0.0046).":[218],"Conclusion":[219],"findings":[221],"suggest":[222],"that":[223],"provides":[227],"improved":[228],"coprological":[238],"particularly":[240],"low-intensity":[242],"infections.":[245],"method":[247],"may":[248],"also":[249],"have":[250],"utility":[251],"epidemiological":[253],"surveillance":[254],"flukicide":[256],"efficacy":[257],"studies,":[258],"although":[259],"interpretation":[260],"should":[261],"be":[262],"considered":[263],"context":[266],"design":[270],"use":[273],"standard.":[278]},"counts_by_year":[],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2026-11-03T00:00:00"}
