{"id":"https://openalex.org/W7225112985","doi":"https://doi.org/10.1177/08927790261502954","title":"Optimizing Laser Settings for Holmium Laser Enucleation of the Prostate: A Randomized Controlled Trial","display_name":"Optimizing Laser Settings for Holmium Laser Enucleation of the Prostate: A Randomized Controlled Trial","publication_year":2026,"publication_date":"2026-11-02","ids":{"openalex":"https://openalex.org/W7225112985","doi":"https://doi.org/10.1177/08927790261502954","pmid":"https://pubmed.ncbi.nlm.nih.gov/42969923"},"language":"en","primary_location":{"id":"doi:10.1177/08927790261502954","doi":"https://doi.org/10.1177/08927790261502954","is_oa":false,"landing_page_url":"https://doi.org/10.1177/08927790261502954","pdf_url":null,"source":{"id":"https://openalex.org/S182300451","display_name":"Journal of Endourology","issn_l":"0892-7790","issn":["0892-7790","1557-900X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Endourology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5026478377","display_name":"Jenny N. Guo","orcid":"https://orcid.org/0000-0002-5959-2966","observed_orcids":["https://orcid.org/0000-0002-5959-2966"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jenny Guo","raw_affiliation_strings":["From the Department of Urology, Emory University School of Medicine, Atlanta, Georgia, USA"],"raw_orcid":"https://orcid.org/0000-0002-5959-2966","affiliations":[{"raw_affiliation_string":"From the Department of Urology, Emory University School of Medicine, Atlanta, Georgia, USA","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5138892943","display_name":"Jack Thomas Peterson","orcid":"https://orcid.org/0009-0006-6756-2800","observed_orcids":["https://orcid.org/0009-0006-6756-2800"]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jack T. Peterson","raw_affiliation_strings":["Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA","institution_ids":["https://openalex.org/I111979921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5134070587","display_name":"Amir Patel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amir Patel","raw_affiliation_strings":["Department of Urology, Oregon Health and Science University, Portland, Oregon, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Oregon Health and Science University, Portland, Oregon, USA","institution_ids":["https://openalex.org/I165690674"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5120406882","display_name":"Jodhel Destina","orcid":"https://orcid.org/0009-0000-1206-4608","observed_orcids":["https://orcid.org/0009-0000-1206-4608"]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jodhel Destina","raw_affiliation_strings":["Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA"],"raw_orcid":"https://orcid.org/0009-0000-1206-4608","affiliations":[{"raw_affiliation_string":"Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA","institution_ids":["https://openalex.org/I111979921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5135149368","display_name":"Perry Xu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Perry Xu","raw_affiliation_strings":["Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA","institution_ids":["https://openalex.org/I111979921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015140382","display_name":"Nabila Reem Khondakar","orcid":"https://orcid.org/0000-0003-1269-7274","observed_orcids":["https://orcid.org/0000-0003-1269-7274"]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nabila Khondakar","raw_affiliation_strings":["Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA"],"raw_orcid":"https://orcid.org/0000-0003-1269-7274","affiliations":[{"raw_affiliation_string":"Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA","institution_ids":["https://openalex.org/I111979921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026447737","display_name":"Alyssa McDonald","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alyssa McDonald","raw_affiliation_strings":["Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA","institution_ids":["https://openalex.org/I111979921"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5017941913","display_name":"Amy Elizabeth Krambeck","orcid":"https://orcid.org/0000-0001-8255-598X","observed_orcids":["https://orcid.org/0000-0001-8255-598X"]},"institutions":[{"id":"https://openalex.org/I111979921","display_name":"Northwestern University","ror":"https://ror.org/000e0be47","country_code":"US","type":"education","lineage":["https://openalex.org/I111979921"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amy Krambeck","raw_affiliation_strings":["Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA","institution_ids":["https://openalex.org/I111979921"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5026478377"],"corresponding_institution_ids":["https://openalex.org/I150468666"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.89061489,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"8927790261502954","last_page":"8927790261502954"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10279","display_name":"Urinary Bladder and Prostate Research","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10279","display_name":"Urinary Bladder and Prostate Research","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10606","display_name":"Kidney Stones and Urolithiasis Treatments","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/holmium-laser-enucleation-of-the-prostate","display_name":"holmium laser enucleation of the prostate","score":0.9990000128746033},{"id":"https://openalex.org/keywords/laser-energy-settings","display_name":"laser energy settings","score":0.9559999704360962},{"id":"https://openalex.org/keywords/pulse-frequency","display_name":"pulse frequency","score":0.6830000281333923},{"id":"https://openalex.org/keywords/pulse-modulation","display_name":"pulse modulation","score":0.5370000004768372},{"id":"https://openalex.org/keywords/operative-time","display_name":"operative time","score":0.843999981880188},{"id":"https://openalex.org/keywords/postoperative-urinary-incontinence","display_name":"postoperative urinary incontinence","score":0.8090000152587891},{"id":"https://openalex.org/keywords/postoperative-complications","display_name":"postoperative complications","score":0.6970000267028809},{"id":"https://openalex.org/keywords/benign-prostatic-hyperplasia","display_name":"benign prostatic hyperplasia","score":0.7860000133514404},{"id":"https://openalex.org/keywords/international-prostate-symptom-score","display_name":"International Prostate Symptom Score","score":0.8379999995231628}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9438999891281128},{"id":"https://openalex.org/C188261085","wikidata":"https://www.wikidata.org/wiki/Q5380862","display_name":"Enucleation","level":2,"score":0.8327999711036682},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.7131999731063843},{"id":"https://openalex.org/C520434653","wikidata":"https://www.wikidata.org/wiki/Q38867","display_name":"Laser","level":2,"score":0.6324999928474426},{"id":"https://openalex.org/C2776235491","wikidata":"https://www.wikidata.org/wiki/Q9625","display_name":"Prostate","level":3,"score":0.5310999751091003},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.5178999900817871},{"id":"https://openalex.org/C540056406","wikidata":"https://www.wikidata.org/wiki/Q1846","display_name":"Holmium","level":3,"score":0.5011000037193298},{"id":"https://openalex.org/C3018023364","wikidata":"https://www.wikidata.org/wiki/Q425265","display_name":"Significant difference","level":2,"score":0.4239000082015991},{"id":"https://openalex.org/C2985973956","wikidata":"https://www.wikidata.org/wiki/Q1617745","display_name":"High energy","level":2,"score":0.3158999979496002},{"id":"https://openalex.org/C2776829320","wikidata":"https://www.wikidata.org/wiki/Q847796","display_name":"Laser surgery","level":3,"score":0.2994000017642975},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.29919999837875366},{"id":"https://openalex.org/C2780167933","wikidata":"https://www.wikidata.org/wiki/Q1550652","display_name":"Pulse (music)","level":3,"score":0.25600001215934753}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1177/08927790261502954","doi":"https://doi.org/10.1177/08927790261502954","is_oa":false,"landing_page_url":"https://doi.org/10.1177/08927790261502954","pdf_url":null,"source":{"id":"https://openalex.org/S182300451","display_name":"Journal of Endourology","issn_l":"0892-7790","issn":["0892-7790","1557-900X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Endourology","raw_type":"journal-article"},{"id":"pmid:42969923","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42969923","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of endourology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Randomized Controlled Trial","id":"https://openalex.org/study-designs/randomized-controlled-trial"},{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W2026896502","https://openalex.org/W2122301563","https://openalex.org/W2126644512","https://openalex.org/W2777994776","https://openalex.org/W2884710531","https://openalex.org/W2961789730","https://openalex.org/W2991291646","https://openalex.org/W3008512194","https://openalex.org/W3119451866","https://openalex.org/W3121071092","https://openalex.org/W3132450145","https://openalex.org/W4230521493","https://openalex.org/W4323365143","https://openalex.org/W4385330633","https://openalex.org/W4405417114"],"related_works":["https://openalex.org/W4285184886","https://openalex.org/W3121071092","https://openalex.org/W7018123566","https://openalex.org/W4323365143","https://openalex.org/W7214999439","https://openalex.org/W2751491347","https://openalex.org/W3049719236","https://openalex.org/W2775778768","https://openalex.org/W4386106934","https://openalex.org/W4405417114"],"abstract_inverted_index":{"INTRODUCTION:":[0],"Studies":[1],"validating":[2],"the":[3,14,129,149,156,175,181],"optimal":[4],"high-power":[5,77],"laser":[6,11,29,62,80,170],"energy":[7,63,185],"settings":[8,30,64,171],"for":[9,86,92,172],"holmium":[10,79],"enucleation":[12],"of":[13,21,65,131,180],"prostate":[15,54],"(HoLEP)":[16],"are":[17],"lacking.":[18],"The":[19],"goal":[20],"our":[22],"study":[23],"is":[24,144],"to":[25,47,61],"determine":[26],"if":[27],"different":[28],"during":[31],"HoLEP":[32,52],"influence":[33],"operative":[34,150],"time":[35],"primarily":[36],"and":[37,40,68,109,152,165,178],"postoperative":[38,153],"symptoms":[39],"complications":[41,154],"secondarily.":[42],"METHODS:":[43],"From":[44],"March":[45],"2024":[46],"April":[48],"2025,":[49],"patients":[50],"undergoing":[51],"with":[53,81,96,155],"measurements":[55],"<200":[56],"mL":[57],"were":[58,90,118],"randomized":[59],"1:1:1":[60],"2":[66,157,161,166],"Joules":[67],"40,":[69],"50,":[70],"or":[71,133],"60":[72,168],"Hertz":[73],"(Hz)":[74],"(NCT06531473).":[75],"A":[76],"120-watt":[78],"pulse":[82],"modulation":[83],"was":[84,125],"used":[85],"all":[87],"patients.":[88],"Patients":[89],"followed":[91],"3":[93],"months":[94],"postoperatively":[95],"daily":[97],"surveys":[98,102],"until":[99,106,113],"day":[100,105,107,114],"14,":[101],"every":[103],"third":[104],"30,":[108],"then":[110],"monthly":[111],"thereafter":[112],"90.":[115],"Postoperative":[116],"outcomes":[117],"manually":[119],"charted.":[120],"RESULTS:":[121],"=":[122],"0.8).":[123],"There":[124],"no":[126,145],"difference":[127,147],"in":[128,148],"change":[130],"IPSS":[132],"Michigan":[134],"Incontinence":[135],"Symptom":[136],"Index":[137],"scores":[138],"between":[139],"groups.":[140],"CONCLUSION:":[141],"Overall,":[142],"there":[143],"significant":[146],"times":[151],"J":[158,162,167],"40":[159],"Hz,":[160,164],"50":[163],"Hz":[169],"HoLEP,":[173],"affirming":[174],"broad":[176],"safety":[177],"efficacy":[179],"procedure":[182],"across":[183],"diverse":[184],"configurations.":[186]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-11-03T00:00:00"}