{"id":"https://openalex.org/W7225111444","doi":"https://doi.org/10.6084/m9.figshare.34886523","title":"Dietary inclusion of 10% Azolla pinnata leaf meal optimises rabbit growth via gut mTOR downstream target p70S6k1 activation and Enterobacteriaceae suppression","display_name":"Dietary inclusion of 10% Azolla pinnata leaf meal optimises rabbit growth via gut mTOR downstream target p70S6k1 activation and Enterobacteriaceae suppression","publication_year":2026,"publication_date":"2026-11-02","ids":{"openalex":"https://openalex.org/W7225111444","doi":"https://doi.org/10.6084/m9.figshare.34886523"},"language":"en","primary_location":{"id":"doi:10.6084/m9.figshare.34886523","doi":"https://doi.org/10.6084/m9.figshare.34886523","is_oa":true,"landing_page_url":"https://doi.org/10.6084/m9.figshare.34886523","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["datacite"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doi.org/10.6084/m9.figshare.34886523","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5073484352","display_name":"Alzahraa M. Abdelatty","orcid":"https://orcid.org/0000-0002-6544-5145","observed_orcids":["https://orcid.org/0000-0002-6544-5145"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Alzahraa M. Abdelatty","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101298719","display_name":"Mahmoud I. Ibrahim","orcid":"https://orcid.org/0000-0002-4895-4677","observed_orcids":["https://orcid.org/0000-0002-4895-4677","https://orcid.org/0000-0002-4261-8795"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mahmoud I. Ibrahim","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160328811","display_name":"Mohamed R. Mousa","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mohamed R. Mousa","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035313490","display_name":"Iman B. Shaheed","orcid":"https://orcid.org/0000-0002-6877-2256","observed_orcids":["https://orcid.org/0000-0002-6877-2256"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Iman B. Shaheed","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043764833","display_name":"Mahmoud M. A. Moustafa","orcid":"https://orcid.org/0000-0001-5392-052X","observed_orcids":["https://orcid.org/0000-0001-5392-052X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mahmoud M. A. Moustafa","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160354008","display_name":"Omar A. A. Farid","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Omar A. A. Farid","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5153592973","display_name":"Gehad E. Eisa","orcid":"https://orcid.org/0000-0002-8307-2987","observed_orcids":["https://orcid.org/0000-0002-8307-2987"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gehad E. Eisa","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062751234","display_name":"Massimo Bionaz","orcid":"https://orcid.org/0000-0002-0674-1892","observed_orcids":["https://orcid.org/0000-0002-0674-1892"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Massimo Bionaz","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039636100","display_name":"Sebastiano Busato","orcid":"https://orcid.org/0000-0002-2542-3443","observed_orcids":["https://orcid.org/0000-0002-2542-3443"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sebastiano Busato","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160377952","display_name":"Sobhy M. A. Sallam","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sobhy M. A. Sallam","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025160415","display_name":"Ahmed A. Elolimy","orcid":"https://orcid.org/0000-0003-0903-1340","observed_orcids":["https://orcid.org/0000-0003-0903-1340"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ahmed A. Elolimy","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5153667852","display_name":"Shereen A. Mohamed","orcid":"https://orcid.org/0000-0003-1922-6803","observed_orcids":["https://orcid.org/0000-0003-1922-6803"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shereen A. Mohamed","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.84754663,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12674","display_name":"Rabbits: Nutrition, Reproduction, Health","score":0.899399995803833,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12674","display_name":"Rabbits: Nutrition, Reproduction, Health","score":0.899399995803833,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10152","display_name":"Animal Nutrition and Physiology","score":0.09849999845027924,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10098","display_name":"Ruminant Nutrition and Digestive Physiology","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/azolla-pinnata","display_name":"Azolla pinnata","score":0.8970000147819519},{"id":"https://openalex.org/keywords/leaf-meal","display_name":"leaf powder","score":0.8130000233650208},{"id":"https://openalex.org/keywords/rabbit-growth-performance","display_name":"rabbit growth performance","score":0.8690000176429749},{"id":"https://openalex.org/keywords/p70s6k1","display_name":"p70S6K1","score":0.8519999980926514},{"id":"https://openalex.org/keywords/mtor-signaling","display_name":"mTOR signaling","score":0.9350000023841858},{"id":"https://openalex.org/keywords/enterobacteriaceae","display_name":"Enterobacteriaceae","score":0.9419999718666077},{"id":"https://openalex.org/keywords/cecal-microbiota","display_name":"cecal microbiota","score":0.8709999918937683},{"id":"https://openalex.org/keywords/caecal-volatile-fatty-acids","display_name":"caecal volatile fatty acids","score":0.8529999852180481},{"id":"https://openalex.org/keywords/intestinal-mucin","display_name":"intestinal mucin","score":0.8009999990463257},{"id":"https://openalex.org/keywords/intestinal-barrier","display_name":"intestinal barrier","score":0.8330000042915344},{"id":"https://openalex.org/keywords/hepatic-oxidative-stress","display_name":"hepatic oxidative stress","score":0.953000009059906},{"id":"https://openalex.org/keywords/gsh-gssg-ratio","display_name":"GSH/GSSG ratio","score":0.8379999995231628},{"id":"https://openalex.org/keywords/dietary-inclusion","display_name":"dietary inclusion","score":0.44600000977516174},{"id":"https://openalex.org/keywords/weaned-rabbits","display_name":"weaned rabbits","score":0.5379999876022339},{"id":"https://openalex.org/keywords/protein-efficiency-ratio","display_name":"protein efficiency ratio","score":0.6269999742507935},{"id":"https://openalex.org/keywords/relative-growth-rate","display_name":"relative growth rate","score":0.6330000162124634},{"id":"https://openalex.org/keywords/acetate","display_name":"acetate","score":0.4259999990463257}],"concepts":[{"id":"https://openalex.org/C179264091","wikidata":"https://www.wikidata.org/wiki/Q410862","display_name":"Mucin","level":2,"score":0.6067000031471252},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5565999746322632},{"id":"https://openalex.org/C61716771","wikidata":"https://www.wikidata.org/wiki/Q496","display_name":"Feces","level":2,"score":0.5303000211715698},{"id":"https://openalex.org/C2781317952","wikidata":"https://www.wikidata.org/wiki/Q4878190","display_name":"Caecum","level":2,"score":0.4977000057697296},{"id":"https://openalex.org/C2779704485","wikidata":"https://www.wikidata.org/wiki/Q3825240","display_name":"Lachnospiraceae","level":5,"score":0.48579999804496765},{"id":"https://openalex.org/C2778345441","wikidata":"https://www.wikidata.org/wiki/Q6460735","display_name":"Meal","level":2,"score":0.4805999994277954},{"id":"https://openalex.org/C2778910516","wikidata":"https://www.wikidata.org/wiki/Q380136","display_name":"Enterobacteriaceae","level":4,"score":0.44369998574256897},{"id":"https://openalex.org/C2777116383","wikidata":"https://www.wikidata.org/wiki/Q18029657","display_name":"Mucin 2","level":4,"score":0.40709999203681946},{"id":"https://openalex.org/C539455810","wikidata":"https://www.wikidata.org/wiki/Q739734","display_name":"Gut flora","level":2,"score":0.38920000195503235},{"id":"https://openalex.org/C2777507495","wikidata":"https://www.wikidata.org/wiki/Q185317","display_name":"Cecum","level":2,"score":0.3725999891757965},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.36959999799728394},{"id":"https://openalex.org/C100544194","wikidata":"https://www.wikidata.org/wiki/Q41760","display_name":"Fermentation","level":2,"score":0.30660000443458557},{"id":"https://openalex.org/C2778772119","wikidata":"https://www.wikidata.org/wiki/Q6058862","display_name":"Fatty liver","level":3,"score":0.30399999022483826},{"id":"https://openalex.org/C3019368612","wikidata":"https://www.wikidata.org/wiki/Q17154506","display_name":"Intestinal mucosa","level":2,"score":0.30309998989105225},{"id":"https://openalex.org/C57600042","wikidata":"https://www.wikidata.org/wiki/Q227564","display_name":"Oxidative phosphorylation","level":2,"score":0.30219998955726624},{"id":"https://openalex.org/C2780320433","wikidata":"https://www.wikidata.org/wiki/Q3403879","display_name":"Weight gain","level":3,"score":0.29649999737739563},{"id":"https://openalex.org/C2780854706","wikidata":"https://www.wikidata.org/wiki/Q900970","display_name":"Pyruvate kinase","level":4,"score":0.28850001096725464},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.2833999991416931},{"id":"https://openalex.org/C140793950","wikidata":"https://www.wikidata.org/wiki/Q168091","display_name":"Animal science","level":1,"score":0.28299999237060547},{"id":"https://openalex.org/C2909545319","wikidata":"https://www.wikidata.org/wiki/Q864693","display_name":"Chicken Liver","level":3,"score":0.2775000035762787},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.2727000117301941},{"id":"https://openalex.org/C147583825","wikidata":"https://www.wikidata.org/wiki/Q620876","display_name":"Body weight","level":2,"score":0.2720000147819519},{"id":"https://openalex.org/C2777226302","wikidata":"https://www.wikidata.org/wiki/Q233345","display_name":"Ileum","level":2,"score":0.26829999685287476},{"id":"https://openalex.org/C11960822","wikidata":"https://www.wikidata.org/wiki/Q242736","display_name":"Phosphorylation","level":2,"score":0.2513999938964844}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.6084/m9.figshare.34886523","doi":"https://doi.org/10.6084/m9.figshare.34886523","is_oa":true,"landing_page_url":"https://doi.org/10.6084/m9.figshare.34886523","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"},{"id":"doi:10.6084/m9.figshare.34886523.v1","doi":"https://doi.org/10.6084/m9.figshare.34886523.v1","is_oa":true,"landing_page_url":"https://doi.org/10.6084/m9.figshare.34886523.v1","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"}],"best_oa_location":{"id":"doi:10.6084/m9.figshare.34886523","doi":"https://doi.org/10.6084/m9.figshare.34886523","is_oa":true,"landing_page_url":"https://doi.org/10.6084/m9.figshare.34886523","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"},"sustainable_development_goals":[{"display_name":"Zero hunger","score":0.958299994468689,"id":"https://metadata.un.org/sdg/2"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3200108020","https://openalex.org/W3203282402","https://openalex.org/W3112989712","https://openalex.org/W7160919924","https://openalex.org/W2921912778","https://openalex.org/W4295540321","https://openalex.org/W4321497719","https://openalex.org/W2775917810","https://openalex.org/W2106519519","https://openalex.org/W2165170323"],"abstract_inverted_index":{"This":[0],"study":[1,210],"evaluated":[2],"the":[3,13,33,114,168,201,208,232,246,264,282,304,325],"effects":[4],"of":[5,36,105,151,156,161,180,192,203,226,250],"dietary":[6,60],"Azolla":[7,255,294],"leaf":[8,256,295],"meal":[9,257,296],"(ALM)":[10,258,297],"inclusion":[11,225,259,298],"on":[12,244],"growth":[14,135],"performance,":[15],"caecal":[16,86,107,165,193,280,322],"fermentation":[17],"profiles,":[18],"hepatic":[19,90],"oxidative":[20,269,309],"status,":[21],"intestinal":[22,95,181,273,314],"mucosal":[23],"barrier":[24,277,318],"and":[25,74,97,102,118,133,158,167,216,238,267,275,307,316],"gastrointestinal":[26],"p70S6K1":[27,99,182,214,284,327],"(ribosomal":[28],"protein":[29,129,285,289,328,332],"S6":[30],"kinase":[31],"beta-1)":[32],"downstream":[34,248],"target":[35,249],"rapamycin":[37],"(mTOR)":[38],"signalling":[39],"pathway":[40],"in":[41,116,125,140,196,221,231],"growing":[42],"rabbits.":[43,222],"Eighty":[44],"weaned":[45],"male":[46],"V-Line":[47],"rabbits":[48,197],"were":[49,109,143],"blocked":[50],"by":[51],"their":[52],"body":[53,126],"weight":[54,127],"before":[55],"random":[56],"assignment":[57],"to":[58,229,253,286,292,329],"four":[59],"groups":[61],"(n":[62],"=":[63],"20/group):":[64],"0%":[65],"ALM":[66,69,72,76,163,177,188,227],"(CON),":[67],"10%":[68,230,254,293],"(AZO10),":[70],"20%":[71],"(AZO20)":[73],"30%":[75,162],"(AZO30).":[77],"The":[78,190],"experimental":[79],"period":[80],"was":[81,113,120],"45":[82],"d.":[83],"Growth":[84],"indices,":[85],"volatile":[87],"fatty":[88],"acids,":[89],"antioxidants,":[91],"histomorphology,":[92],"mucin":[93,172,274,315],"histochemistry,":[94],"total":[96],"phosphorylated":[98],"(P-p70S6K1)":[100],"expression,":[101],"gene":[103],"abundance":[104,191,219],"selected":[106,217],"microbiota":[108],"quantified.":[110],"Feed":[111],"intake":[112],"lowest":[115],"AZO10,":[117],"that":[119],"associated":[121,144],"with":[122,145,175,186],"an":[123,149],"increase":[124,150],"gain,":[128],"efficiency":[130],"ratio":[131,266,306],"(PER)":[132],"relative":[134],"rate":[136],"(RGR).":[137],"Most":[138],"changes":[139],"liver":[141,239],"metabolites":[142],"AZO10":[146],"group,":[147],"including":[148],"GSH:GSSG":[152,265,305],"ratio,":[153],"decreased":[154,195],"levels":[155],"ATP":[157],"8-hydroxydeoxyguanosine.":[159],"Inclusion":[160],"reduced":[164],"acetate":[166],"acetate:propionate":[169],"ratio.":[170],"Intestinal":[171],"increased":[173,184],"linearly":[174,185],"increasing":[176,187],"inclusion.":[178,189],"Phosphorylation":[179],"also":[183],"Enterobacteriaceae":[194],"fed":[198],"ALM.":[199],"To":[200],"best":[202],"our":[204],"knowledge,":[205],"this":[206],"is":[207],"first":[209],"investigating":[211],"ALM-induced":[212],"gut":[213,237,283,326],"activation":[215],"microbial":[218],"shifts":[220],"In":[223],"conclusion,":[224],"up":[228],"rabbit":[233,261,300],"diet":[234],"may":[235],"benefit":[236],"health":[240],"through":[241],"its":[242],"impact":[243],"p70S6K1,":[245],"critical":[247],"mTOR.":[251],"Up":[252,291],"optimises":[260,299],"growth.It":[262],"improves":[263,303],"lowers":[268,308],"damage":[270,310],"markers.It":[271],"regulates":[272,313],"cell":[276,317],"functions.Reduces":[278],"harmful":[279,321],"Enterobacteriaceae.Activates":[281],"boost":[287,330],"tissue":[288,331],"synthesis.":[290,333],"growth.":[301],"It":[302,312],"markers.":[311],"functions.":[319],"Reduces":[320],"Enterobacteriaceae.":[323],"Activates":[324]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-11-03T00:00:00"}