{"id":"https://openalex.org/W7225086889","doi":"https://doi.org/10.21203/rs.3.rs-11375374/v1","title":"Impact of Low-Intensity Occlusive Cardiorespiratory Training on Office Blood Pressure and Physical Fitness in Adults with Hypertension","display_name":"Impact of Low-Intensity Occlusive Cardiorespiratory Training on Office Blood Pressure and Physical Fitness in Adults with Hypertension","publication_year":2026,"publication_date":"2026-11-03","ids":{"openalex":"https://openalex.org/W7225086889","doi":"https://doi.org/10.21203/rs.3.rs-11375374/v1"},"language":"en","primary_location":{"id":"doi:10.21203/rs.3.rs-11375374/v1","doi":"https://doi.org/10.21203/rs.3.rs-11375374/v1","is_oa":true,"landing_page_url":"https://doi.org/10.21203/rs.3.rs-11375374/v1","pdf_url":"https://www.researchsquare.com/article/rs-11375374/latest.pdf","source":{"id":"https://openalex.org/S4306525896","display_name":"Research Square","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Research Square","raw_type":"posted-content"},"volume":null,"type":"preprint","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.researchsquare.com/article/rs-11375374/latest.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5160338979","display_name":"M. Santa Mar\u00eda","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M. Santa Mar\u00eda","raw_affiliation_strings":["Hospital Interzonal General de Agudos Gral San Mart\u00edn"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital Interzonal General de Agudos Gral San Mart\u00edn","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160338048","display_name":"J. Minetto","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J. Minetto","raw_affiliation_strings":["Hospital Interzonal General de Agudos Gral San Mart\u00edn"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital Interzonal General de Agudos Gral San Mart\u00edn","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160338264","display_name":"G. Cerri","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G. Cerri","raw_affiliation_strings":["Hospital Interzonal General de Agudos Gral San Mart\u00edn"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital Interzonal General de Agudos Gral San Mart\u00edn","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160349817","display_name":"S. Collado","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S. Collado","raw_affiliation_strings":["Hospital Interzonal General de Agudos Gral San Mart\u00edn"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital Interzonal General de Agudos Gral San Mart\u00edn","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160385477","display_name":"M. Barreda\u00b9","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M. Barreda\u00b9","raw_affiliation_strings":["Hospital Interzonal General de Agudos Gral San Mart\u00edn"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital Interzonal General de Agudos Gral San Mart\u00edn","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160349293","display_name":"F. Staropoli","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"F. Staropoli","raw_affiliation_strings":["Hospital Interzonal General de Agudos Gral San Mart\u00edn"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital Interzonal General de Agudos Gral San Mart\u00edn","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5160346212","display_name":"W. Espeche","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"W. Espeche","raw_affiliation_strings":["Hospital Interzonal General de Agudos Gral San Mart\u00edn"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hospital Interzonal General de Agudos Gral San Mart\u00edn","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11209","display_name":"Cardiovascular and exercise physiology","score":0.9721999764442444,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11209","display_name":"Cardiovascular and exercise physiology","score":0.9721999764442444,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10144","display_name":"Blood Pressure and Hypertension Studies","score":0.025200000032782555,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10352","display_name":"Physical Activity and Health","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.9959999918937683},{"id":"https://openalex.org/keywords/blood-flow-restriction","display_name":"blood flow restriction","score":0.8759999871253967},{"id":"https://openalex.org/keywords/high-intensity-interval-training","display_name":"high-intensity interval training","score":0.9710000157356262},{"id":"https://openalex.org/keywords/moderate-intensity-continuous-training","display_name":"moderate-intensity continuous training","score":0.9990000128746033},{"id":"https://openalex.org/keywords/office-blood-pressure","display_name":"office blood pressure","score":0.9850000143051147},{"id":"https://openalex.org/keywords/diastolic-blood-pressure","display_name":"diastolic blood pressure","score":0.9290000200271606},{"id":"https://openalex.org/keywords/physical-fitness","display_name":"physical fitness","score":0.9909999966621399},{"id":"https://openalex.org/keywords/aerobic-exercise","display_name":"aerobic exercise","score":0.6830000281333923}],"concepts":[{"id":"https://openalex.org/C117437137","wikidata":"https://www.wikidata.org/wiki/Q5038720","display_name":"Cardiorespiratory fitness","level":2,"score":0.934499979019165},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8842999935150146},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.7190999984741211},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.6966999769210815},{"id":"https://openalex.org/C171687745","wikidata":"https://www.wikidata.org/wiki/Q309252","display_name":"Physical fitness","level":2,"score":0.5742999911308289},{"id":"https://openalex.org/C2776193436","wikidata":"https://www.wikidata.org/wiki/Q236232","display_name":"Waist","level":3,"score":0.5077999830245972},{"id":"https://openalex.org/C2777973682","wikidata":"https://www.wikidata.org/wiki/Q1558681","display_name":"Interval training","level":2,"score":0.4814000129699707},{"id":"https://openalex.org/C181588539","wikidata":"https://www.wikidata.org/wiki/Q219067","display_name":"Physical exercise","level":2,"score":0.41100001335144043},{"id":"https://openalex.org/C2815619","wikidata":"https://www.wikidata.org/wiki/Q5165527","display_name":"Continuous training","level":2,"score":0.41029998660087585},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.35589998960494995},{"id":"https://openalex.org/C50440223","wikidata":"https://www.wikidata.org/wiki/Q1475848","display_name":"Risk factor","level":2,"score":0.3122999966144562},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.30070000886917114},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.298799991607666},{"id":"https://openalex.org/C2780221984","wikidata":"https://www.wikidata.org/wiki/Q131191","display_name":"Body mass index","level":2,"score":0.29179999232292175},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.28529998660087585},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.28139999508857727},{"id":"https://openalex.org/C2777211547","wikidata":"https://www.wikidata.org/wiki/Q17141490","display_name":"Training (meteorology)","level":2,"score":0.2614000141620636},{"id":"https://openalex.org/C123550912","wikidata":"https://www.wikidata.org/wiki/Q12834857","display_name":"Strength training","level":2,"score":0.260699987411499}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.21203/rs.3.rs-11375374/v1","doi":"https://doi.org/10.21203/rs.3.rs-11375374/v1","is_oa":true,"landing_page_url":"https://doi.org/10.21203/rs.3.rs-11375374/v1","pdf_url":"https://www.researchsquare.com/article/rs-11375374/latest.pdf","source":{"id":"https://openalex.org/S4306525896","display_name":"Research Square","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Research Square","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.21203/rs.3.rs-11375374/v1","doi":"https://doi.org/10.21203/rs.3.rs-11375374/v1","is_oa":true,"landing_page_url":"https://doi.org/10.21203/rs.3.rs-11375374/v1","pdf_url":"https://www.researchsquare.com/article/rs-11375374/latest.pdf","source":{"id":"https://openalex.org/S4306525896","display_name":"Research Square","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Research Square","raw_type":"posted-content"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/randomized-controlled-trial","display_name":"Randomized Controlled Trial"},{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7225086889.pdf","grobid_xml":"https://content.openalex.org/works/W7225086889.grobid-xml"},"referenced_works_count":17,"referenced_works":["https://openalex.org/W1971474283","https://openalex.org/W2048443632","https://openalex.org/W2089901353","https://openalex.org/W2122190417","https://openalex.org/W2159294672","https://openalex.org/W2166758089","https://openalex.org/W2555189237","https://openalex.org/W2593177058","https://openalex.org/W2904698845","https://openalex.org/W2944877286","https://openalex.org/W2977957581","https://openalex.org/W3092861045","https://openalex.org/W3157857666","https://openalex.org/W3182309572","https://openalex.org/W3193823764","https://openalex.org/W4244168426","https://openalex.org/W4391999401"],"related_works":["https://openalex.org/W2904822252","https://openalex.org/W6940370749","https://openalex.org/W4415369666","https://openalex.org/W2778555117","https://openalex.org/W2803036062","https://openalex.org/W4387062210","https://openalex.org/W4410046710","https://openalex.org/W4408340113","https://openalex.org/W2400711417","https://openalex.org/W2807809544"],"abstract_inverted_index":{"Abstract":[0],"Background":[1],"Hypertension":[2],"is":[3,256],"the":[4,15,68,116,197,201,204],"leading":[5],"modifiable":[6],"risk":[7],"factor":[8],"for":[9,17,147,184,258],"cardiovascular":[10],"morbidity":[11],"and":[12,33,82,100,159,170,193,214,262,280],"mortality,":[13],"underscoring":[14],"need":[16],"non-pharmacological":[18],"strategies":[19],"such":[20],"as":[21,55],"exercise":[22,161,205],"to":[23,189,274],"optimize":[24],"blood":[25,43,87,98,216,247],"pressure":[26,99,217,248],"control.":[27],"Although":[28],"moderate-intensity":[29,78],"continuous":[30,79,84],"training":[31,36,51,73,76,80,85,255,279],"(MICT)":[32],"high-intensity":[34],"interval":[35,75],"(HIIT)":[37],"are":[38],"supported":[39],"by":[40],"substantial":[41],"evidence,":[42],"flow":[44,88],"restriction":[45,89],"(BFR)":[46],"combined":[47,207],"with":[48,86,105,200,221,267,283],"low-intensity":[49,83],"cardiorespiratory":[50,72],"(LICT)":[52],"has":[53],"emerged":[54],"a":[56,62,93,153,240,284],"promising":[57],"alternative":[58],"because":[59],"it":[60],"imposes":[61],"lower":[63],"workload.":[64],"Objective":[65],"To":[66],"compare":[67],"effects":[69],"of":[70,92,120,276],"three":[71,160,180,231],"modalities\u2014high-intensity":[74],"(HIIT),":[77],"(MICT),":[81],"(LICT-BFR)\u2014with":[90],"those":[91,275],"control":[94,154,202,264],"group":[95,155],"on":[96],"office":[97,215,245,289],"physical":[101,212,234],"fitness":[102,213],"in":[103,128,211,224,244,265,288],"patients":[104],"hypertension.":[106,268],"Methods":[107],"This":[108],"randomized":[109],"controlled":[110],"clinical":[111,148],"study":[112],"was":[113,191,281],"conducted":[114],"at":[115],"Cardiometabolic":[117],"Diseases":[118],"Unit":[119],"Hospital":[121],"Interzonal":[122],"General":[123],"de":[124],"Agudos":[125],"San":[126],"Mart\u00edn":[127],"La":[129],"Plata,":[130],"Argentina.":[131],"Sixty":[132],"participants":[133,144,151,195],"were":[134,145],"assessed":[135],"(mean":[136],"age,":[137],"60":[138],"\u00b1":[139],"6":[140],"years).":[141],"After":[142],"eight":[143],"excluded":[146],"reasons,":[149],"52":[150],"remained:":[152],"(n":[156,163,167,172],"=":[157,164,168,173,251],"15)":[158],"groups\u2014HIIT":[162],"10),":[165],"MICT":[166],"13),":[169],"LICT-BFR":[171,238,269],"14).":[174],"The":[175],"intervention":[176],"comprised":[177],"36":[178],"sessions,":[179],"times":[181],"per":[182],"week":[183],"12":[185],"weeks.":[186],"Results":[187],"Loss":[188],"follow-up":[190],"26.9%,":[192],"38":[194],"completed":[196],"study.":[198],"Compared":[199],"group,":[203],"groups":[206],"showed":[208],"significant":[209,242,286],"improvements":[210],"(p":[218],"<":[219],"0.05),":[220],"no":[222],"changes":[223],"body":[225],"weight":[226],"or":[227],"waist":[228],"circumference.":[229],"All":[230],"protocols":[232],"improved":[233],"fitness;":[235],"however,":[236],"only":[237],"produced":[239],"statistically":[241,285],"reduction":[243,287],"diastolic":[246],"(DBP;":[249],"p":[250],"0.044).":[252],"Conclusion":[253],"Cardiorespiratory":[254],"important":[257],"improving":[259],"functional":[260,271],"capacity":[261],"hemodynamic":[263],"people":[266],"provided":[270],"benefits":[272],"comparable":[273],"traditional":[277],"aerobic":[278],"associated":[282],"DBP.":[290]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-11-03T00:00:00"}