{"id":"https://openalex.org/W7225050286","doi":"https://doi.org/10.17340/jkna.2026.0033","title":"Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy Mimicking Tuberculous Meningitis Following Epstein-Barr Virus Infection","display_name":"Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy Mimicking Tuberculous Meningitis Following Epstein-Barr Virus Infection","publication_year":2026,"publication_date":"2026-11-01","ids":{"openalex":"https://openalex.org/W7225050286","doi":"https://doi.org/10.17340/jkna.2026.0033"},"language":"en","primary_location":{"id":"doi:10.17340/jkna.2026.0033","doi":"https://doi.org/10.17340/jkna.2026.0033","is_oa":true,"landing_page_url":"https://doi.org/10.17340/jkna.2026.0033","pdf_url":"https://www.jkna.org/upload/pdf/jkna-44-4-349.pdf","source":{"id":"https://openalex.org/S2764848346","display_name":"Journal of the Korean Neurological Association","issn_l":"1225-7044","issn":["1225-7044","2288-985X"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["kci-registered"],"host_organization":"https://openalex.org/P4324031397","host_organization_name":"Korean Neurological Association","host_organization_lineage":["https://openalex.org/P4324031397"],"host_organization_lineage_names":["Korean Neurological Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the Korean Neurological Association","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.jkna.org/upload/pdf/jkna-44-4-349.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5058296854","display_name":"Sua PARK","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405260934","display_name":"Korea University Anam Hospital","ror":"https://ror.org/04gjj3027","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I197347611","https://openalex.org/I2799980853","https://openalex.org/I4405260934"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Sua Park","raw_affiliation_strings":["Department of Neurology, Korea University Anam Hospital, Seoul, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Korea University Anam Hospital, Seoul, Korea","institution_ids":["https://openalex.org/I4405260934"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007725207","display_name":"\uc774\uc778\uc601","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405260934","display_name":"Korea University Anam Hospital","ror":"https://ror.org/04gjj3027","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I197347611","https://openalex.org/I2799980853","https://openalex.org/I4405260934"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Inyoung Lee","raw_affiliation_strings":["Department of Neurology, Korea University Anam Hospital, Seoul, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Korea University Anam Hospital, Seoul, Korea","institution_ids":["https://openalex.org/I4405260934"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113107328","display_name":"Chan-Nyoung Lee","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405260934","display_name":"Korea University Anam Hospital","ror":"https://ror.org/04gjj3027","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I197347611","https://openalex.org/I2799980853","https://openalex.org/I4405260934"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Chan-Nyoung Lee","raw_affiliation_strings":["Department of Neurology, Korea University Anam Hospital, Seoul, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Korea University Anam Hospital, Seoul, Korea","institution_ids":["https://openalex.org/I4405260934"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5005149591","display_name":"Hayom Kim","orcid":"https://orcid.org/0000-0002-9991-3664","observed_orcids":["https://orcid.org/0000-0002-9991-3664"]},"institutions":[{"id":"https://openalex.org/I4405260934","display_name":"Korea University Anam Hospital","ror":"https://ror.org/04gjj3027","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I197347611","https://openalex.org/I2799980853","https://openalex.org/I4405260934"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Hayom Kim","raw_affiliation_strings":["Department of Neurology, Korea University Anam Hospital, Seoul, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology, Korea University Anam Hospital, Seoul, Korea","institution_ids":["https://openalex.org/I4405260934"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5005149591"],"corresponding_institution_ids":["https://openalex.org/I4405260934"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.8362226,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"44","issue":"4","first_page":"349","last_page":"352"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11627","display_name":"Autoimmune Neurological Disorders and Treatments","score":0.8666999936103821,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11627","display_name":"Autoimmune Neurological Disorders and Treatments","score":0.8666999936103821,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11735","display_name":"Peripheral Neuropathies and Disorders","score":0.02199999988079071,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11381","display_name":"Infectious Diseases and Tuberculosis","score":0.01720000058412552,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/glial-fibrillary-acidic-protein","display_name":"glial fibrillary acidic protein","score":0.9819999933242798},{"id":"https://openalex.org/keywords/epstein-barr-virus-infection","display_name":"Epstein-Barr virus infection","score":0.8330000042915344},{"id":"https://openalex.org/keywords/cerebral-vasospasm","display_name":"cerebral vasospasm","score":0.7860000133514404},{"id":"https://openalex.org/keywords/anti-gfap-antibodies","display_name":"anti-GFAP antibodies","score":0.8519999980926514},{"id":"https://openalex.org/keywords/methylprednisolone-pulse-therapy","display_name":"methylprednisolone pulse therapy","score":0.9020000100135803},{"id":"https://openalex.org/keywords/therapeutic-plasma-exchange","display_name":"plasma exchange","score":0.9769999980926514},{"id":"https://openalex.org/keywords/encephalopathy","display_name":"encephalopathy","score":0.7049999833106995},{"id":"https://openalex.org/keywords/pleocytosis","display_name":"pleocytosis","score":0.8930000066757202}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8343999981880188},{"id":"https://openalex.org/C2776896556","wikidata":"https://www.wikidata.org/wiki/Q3854687","display_name":"Tuberculous meningitis","level":3,"score":0.7713000178337097},{"id":"https://openalex.org/C2780495277","wikidata":"https://www.wikidata.org/wiki/Q905442","display_name":"Glial fibrillary acidic protein","level":3,"score":0.7703999876976013},{"id":"https://openalex.org/C2779651940","wikidata":"https://www.wikidata.org/wiki/Q54196","display_name":"Cerebrospinal fluid","level":2,"score":0.7148000001907349},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.5372999906539917},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.4878000020980835},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.44279998540878296},{"id":"https://openalex.org/C2777975735","wikidata":"https://www.wikidata.org/wiki/Q130971","display_name":"Mycobacterium tuberculosis","level":3,"score":0.4401000142097473},{"id":"https://openalex.org/C2781069245","wikidata":"https://www.wikidata.org/wiki/Q12204","display_name":"Tuberculosis","level":2,"score":0.4368000030517578},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.4259999990463257},{"id":"https://openalex.org/C2780372218","wikidata":"https://www.wikidata.org/wiki/Q417222","display_name":"Methylprednisolone","level":2,"score":0.4050999879837036},{"id":"https://openalex.org/C2777682930","wikidata":"https://www.wikidata.org/wiki/Q1531490","display_name":"Gliosis","level":2,"score":0.3959999978542328},{"id":"https://openalex.org/C2777961210","wikidata":"https://www.wikidata.org/wiki/Q927148","display_name":"Bronchoalveolar lavage","level":3,"score":0.37049999833106995},{"id":"https://openalex.org/C2781026528","wikidata":"https://www.wikidata.org/wiki/Q48143","display_name":"Meningitis","level":2,"score":0.36649999022483826},{"id":"https://openalex.org/C33619753","wikidata":"https://www.wikidata.org/wiki/Q5014091","display_name":"CSF albumin","level":3,"score":0.36480000615119934},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.3303999900817871},{"id":"https://openalex.org/C2781460105","wikidata":"https://www.wikidata.org/wiki/Q16918461","display_name":"Autoimmune encephalitis","level":4,"score":0.31279999017715454},{"id":"https://openalex.org/C2779075594","wikidata":"https://www.wikidata.org/wiki/Q8084905","display_name":"Autoimmune disease","level":3,"score":0.3075999915599823},{"id":"https://openalex.org/C2992083352","wikidata":"https://www.wikidata.org/wiki/Q693442","display_name":"Subarachnoid haemorrhage","level":3,"score":0.290800005197525},{"id":"https://openalex.org/C83455156","wikidata":"https://www.wikidata.org/wiki/Q199615","display_name":"Encephalitis","level":3,"score":0.289900004863739},{"id":"https://openalex.org/C2778621254","wikidata":"https://www.wikidata.org/wiki/Q2346415","display_name":"Meningoencephalitis","level":2,"score":0.27790001034736633},{"id":"https://openalex.org/C2780898057","wikidata":"https://www.wikidata.org/wiki/Q79448","display_name":"Immunoglobulin G","level":3,"score":0.2660999894142151},{"id":"https://openalex.org/C2910667942","wikidata":"https://www.wikidata.org/wiki/Q48143","display_name":"Cerebrospinal meningitis","level":3,"score":0.25870001316070557}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.17340/jkna.2026.0033","doi":"https://doi.org/10.17340/jkna.2026.0033","is_oa":true,"landing_page_url":"https://doi.org/10.17340/jkna.2026.0033","pdf_url":"https://www.jkna.org/upload/pdf/jkna-44-4-349.pdf","source":{"id":"https://openalex.org/S2764848346","display_name":"Journal of the Korean Neurological Association","issn_l":"1225-7044","issn":["1225-7044","2288-985X"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["kci-registered"],"host_organization":"https://openalex.org/P4324031397","host_organization_name":"Korean Neurological Association","host_organization_lineage":["https://openalex.org/P4324031397"],"host_organization_lineage_names":["Korean Neurological Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the Korean Neurological Association","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.17340/jkna.2026.0033","doi":"https://doi.org/10.17340/jkna.2026.0033","is_oa":true,"landing_page_url":"https://doi.org/10.17340/jkna.2026.0033","pdf_url":"https://www.jkna.org/upload/pdf/jkna-44-4-349.pdf","source":{"id":"https://openalex.org/S2764848346","display_name":"Journal of the Korean Neurological Association","issn_l":"1225-7044","issn":["1225-7044","2288-985X"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["kci-registered"],"host_organization":"https://openalex.org/P4324031397","host_organization_name":"Korean Neurological Association","host_organization_lineage":["https://openalex.org/P4324031397"],"host_organization_lineage_names":["Korean Neurological Association"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the Korean Neurological Association","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7225050286.pdf","grobid_xml":"https://content.openalex.org/works/W7225050286.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4309561665","https://openalex.org/W7008175370","https://openalex.org/W4384524143","https://openalex.org/W4385623419","https://openalex.org/W4413497970","https://openalex.org/W4389448619","https://openalex.org/W3111325197","https://openalex.org/W4296982013","https://openalex.org/W3177929932","https://openalex.org/W4406724622"],"abstract_inverted_index":{"A":[0],"49-year-old":[1],"man":[2],"with":[3],"fever,":[4],"progressive":[5],"encephalopathy,":[6],"lymphocytic":[7],"pleocytosis,":[8],"rising":[9],"cerebrospinal":[10,39],"fluid":[11,40],"adenosine":[12],"deaminase,":[13],"Epstein-Barr":[14],"virus":[15],"DNA":[16],"detection,":[17],"and":[18,35,38,58],"multifocal":[19],"cerebral":[20],"vasospasm":[21],"was":[22],"suspected":[23],"of":[24],"infectious":[25],"or":[26],"tuberculous":[27],"meningitis,":[28],"but":[29],"repeated":[30],"negative":[31],"tests":[32],"for":[33],"tuberculosis":[34],"other":[36],"pathogens":[37],"anti-glial":[41],"fibrillary":[42],"acidic":[43],"protein":[44],"(GFAP)":[45],"antibody":[46],"positivity":[47],"established":[48],"autoimmune":[49],"GFAP":[50],"astrocytopathy,":[51],"which":[52],"improved":[53],"after":[54],"methylprednisolone":[55],"pulse":[56],"therapy":[57],"plasma":[59],"exchange.":[60]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-11-02T00:00:00"}