{"id":"https://openalex.org/W7225045694","doi":"https://doi.org/10.1007/s11033-026-12952-y","title":"Oleuropein and punicic acid induce oxidative stress and cytotoxicity in MCF-7 breast cancer cells, with protection by peroxiredoxin antioxidant proteins","display_name":"Oleuropein and punicic acid induce oxidative stress and cytotoxicity in MCF-7 breast cancer cells, with protection by peroxiredoxin antioxidant proteins","publication_year":2026,"publication_date":"2026-11-01","ids":{"openalex":"https://openalex.org/W7225045694","doi":"https://doi.org/10.1007/s11033-026-12952-y","pmid":"https://pubmed.ncbi.nlm.nih.gov/42967238","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13724668"},"language":"en","primary_location":{"id":"doi:10.1007/s11033-026-12952-y","doi":"https://doi.org/10.1007/s11033-026-12952-y","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s11033-026-12952-y","pdf_url":"https://link.springer.com/content/pdf/10.1007/s11033-026-12952-y.pdf","source":{"id":"https://openalex.org/S197962172","display_name":"Molecular Biology Reports","issn_l":"0301-4851","issn":["0301-4851","1573-4978"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Biology Reports","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://link.springer.com/content/pdf/10.1007/s11033-026-12952-y.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5132851907","display_name":"Samantha Diiorio","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I126350171","display_name":"Fairfield University","ror":"https://ror.org/04z49n283","country_code":"US","type":"education","lineage":["https://openalex.org/I126350171"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Samantha Diiorio","raw_affiliation_strings":["Department of Biology, Fairfield University, Fairfield, CT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Fairfield University, Fairfield, CT, USA","institution_ids":["https://openalex.org/I126350171"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114482841","display_name":"Braden Quitmeyer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32389192","display_name":"University of Alabama at Birmingham","ror":"https://ror.org/008s83205","country_code":"US","type":"education","lineage":["https://openalex.org/I32389192"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Braden Quitmeyer","raw_affiliation_strings":["Graduate Biomedical Sciences, University of Alabama, Birmingham, AL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate Biomedical Sciences, University of Alabama, Birmingham, AL, USA","institution_ids":["https://openalex.org/I32389192"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5005530860","display_name":"Shelley Ann Phelan","orcid":"https://orcid.org/0000-0002-4707-1872","observed_orcids":["https://orcid.org/0000-0002-4707-1872"]},"institutions":[{"id":"https://openalex.org/I126350171","display_name":"Fairfield University","ror":"https://ror.org/04z49n283","country_code":"US","type":"education","lineage":["https://openalex.org/I126350171"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Shelley A. Phelan","raw_affiliation_strings":["Department of Biology, Fairfield University, Fairfield, CT, USA. sphelan@fairfield.edu"],"raw_orcid":"https://orcid.org/0000-0002-4707-1872","affiliations":[{"raw_affiliation_string":"Department of Biology, Fairfield University, Fairfield, CT, USA. sphelan@fairfield.edu","institution_ids":["https://openalex.org/I126350171"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5005530860"],"corresponding_institution_ids":["https://openalex.org/I126350171"],"apc_list":{"value":4290,"currency":"USD","value_usd":4290},"apc_paid":{"value":4290,"currency":"USD","value_usd":4290},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.71910849,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"53","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10909","display_name":"Edible Oils Quality and Analysis","score":0.447299987077713,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10909","display_name":"Edible Oils Quality and Analysis","score":0.447299987077713,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12638","display_name":"Pomegranate: compositions and health benefits","score":0.22130000591278076,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.0689999982714653,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/oleuropein","display_name":"oleuropein","score":1.0},{"id":"https://openalex.org/keywords/punicic-acid","display_name":"punicic acid","score":0.9990000128746033},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.7710000276565552},{"id":"https://openalex.org/keywords/mcf-7-cells","display_name":"MCF-7 cells","score":0.9860000014305115},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.878000020980835},{"id":"https://openalex.org/keywords/cytotoxicity","display_name":"cytotoxicity","score":0.9950000047683716},{"id":"https://openalex.org/keywords/peroxiredoxin","display_name":"peroxiredoxin","score":0.9300000071525574},{"id":"https://openalex.org/keywords/antioxidant-defense","display_name":"antioxidant defense","score":0.7760000228881836},{"id":"https://openalex.org/keywords/mitochondrial-superoxide","display_name":"mitochondrial superoxide","score":0.9549999833106995},{"id":"https://openalex.org/keywords/lipid-peroxidation","display_name":"lipid peroxidation","score":0.996999979019165},{"id":"https://openalex.org/keywords/olive-leaf-extract","display_name":"olive leaf extract","score":0.8009999990463257},{"id":"https://openalex.org/keywords/pomegranate","display_name":"Punica granatum","score":0.8420000076293945},{"id":"https://openalex.org/keywords/anticancer-natural-compounds","display_name":"anticancer natural compounds","score":0.6970000267028809}],"concepts":[{"id":"https://openalex.org/C2777957096","wikidata":"https://www.wikidata.org/wiki/Q402625","display_name":"Oleuropein","level":3,"score":0.8288999795913696},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.751800000667572},{"id":"https://openalex.org/C109316439","wikidata":"https://www.wikidata.org/wiki/Q246181","display_name":"Cytotoxicity","level":3,"score":0.6973999738693237},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.6952999830245972},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5825999975204468},{"id":"https://openalex.org/C2780783641","wikidata":"https://www.wikidata.org/wiki/Q738686","display_name":"MTT assay","level":3,"score":0.567300021648407},{"id":"https://openalex.org/C2780829032","wikidata":"https://www.wikidata.org/wiki/Q898539","display_name":"Lipid peroxidation","level":3,"score":0.5600000023841858},{"id":"https://openalex.org/C48349386","wikidata":"https://www.wikidata.org/wiki/Q424361","display_name":"Reactive oxygen species","level":2,"score":0.5508000254631042},{"id":"https://openalex.org/C109541995","wikidata":"https://www.wikidata.org/wiki/Q1881253","display_name":"MCF-7","level":5,"score":0.5422999858856201},{"id":"https://openalex.org/C2780416994","wikidata":"https://www.wikidata.org/wiki/Q419462","display_name":"Peroxiredoxin","level":4,"score":0.5400999784469604},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.49399998784065247},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.428600013256073},{"id":"https://openalex.org/C96232424","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell","level":3,"score":0.4207000136375427},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.40470001101493835},{"id":"https://openalex.org/C2775881703","wikidata":"https://www.wikidata.org/wiki/Q744577","display_name":"Hydroxytyrosol","level":4,"score":0.35679998993873596},{"id":"https://openalex.org/C53227056","wikidata":"https://www.wikidata.org/wiki/Q189152","display_name":"Viability assay","level":3,"score":0.3319000005722046},{"id":"https://openalex.org/C62112901","wikidata":"https://www.wikidata.org/wiki/Q189159","display_name":"Cell growth","level":2,"score":0.32260000705718994},{"id":"https://openalex.org/C2779005586","wikidata":"https://www.wikidata.org/wiki/Q7087231","display_name":"Olive leaf","level":2,"score":0.30640000104904175},{"id":"https://openalex.org/C2780369685","wikidata":"https://www.wikidata.org/wiki/Q5058184","display_name":"Cell damage","level":2,"score":0.29760000109672546},{"id":"https://openalex.org/C31573885","wikidata":"https://www.wikidata.org/wiki/Q304484","display_name":"Programmed cell death","level":3,"score":0.290800005197525},{"id":"https://openalex.org/C2778175917","wikidata":"https://www.wikidata.org/wiki/Q17125553","display_name":"Mitochondrial ROS","level":3,"score":0.2572000026702881},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.2522999942302704},{"id":"https://openalex.org/C2781397471","wikidata":"https://www.wikidata.org/wiki/Q296910","display_name":"Olea","level":2,"score":0.25200000405311584}],"mesh":[{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002470","descriptor_name":"Cell Survival","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008928","descriptor_name":"Mitochondria","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008928","descriptor_name":"Mitochondria","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015227","descriptor_name":"Lipid Peroxidation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D017382","descriptor_name":"Reactive Oxygen Species","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018384","descriptor_name":"Oxidative Stress","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D039823","descriptor_name":"Iridoids","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D054464","descriptor_name":"Peroxiredoxins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D057888","descriptor_name":"Iridoid Glucosides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D061986","descriptor_name":"MCF-7 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1007/s11033-026-12952-y","doi":"https://doi.org/10.1007/s11033-026-12952-y","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s11033-026-12952-y","pdf_url":"https://link.springer.com/content/pdf/10.1007/s11033-026-12952-y.pdf","source":{"id":"https://openalex.org/S197962172","display_name":"Molecular Biology Reports","issn_l":"0301-4851","issn":["0301-4851","1573-4978"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Biology Reports","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13724668","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13724668/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13724668/pdf/11033_2026_Article_12952.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mol Biol Rep","raw_type":"Text"},{"id":"pmid:42967238","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42967238","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular biology reports","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1007/s11033-026-12952-y","doi":"https://doi.org/10.1007/s11033-026-12952-y","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s11033-026-12952-y","pdf_url":"https://link.springer.com/content/pdf/10.1007/s11033-026-12952-y.pdf","source":{"id":"https://openalex.org/S197962172","display_name":"Molecular Biology Reports","issn_l":"0301-4851","issn":["0301-4851","1573-4978"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular Biology Reports","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320314253","display_name":"Fairfield University","ror":"https://ror.org/04z49n283"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7225045694.pdf","grobid_xml":"https://content.openalex.org/works/W7225045694.grobid-xml"},"referenced_works_count":48,"referenced_works":["https://openalex.org/W1972779889","https://openalex.org/W1976599392","https://openalex.org/W1983937216","https://openalex.org/W2001923529","https://openalex.org/W2011344898","https://openalex.org/W2025639892","https://openalex.org/W2030490972","https://openalex.org/W2038011914","https://openalex.org/W2081728154","https://openalex.org/W2091260015","https://openalex.org/W2095931589","https://openalex.org/W2107873337","https://openalex.org/W2110946623","https://openalex.org/W2113860045","https://openalex.org/W2119944195","https://openalex.org/W2131316166","https://openalex.org/W2144911172","https://openalex.org/W2149828455","https://openalex.org/W2154692564","https://openalex.org/W2163542447","https://openalex.org/W2415627283","https://openalex.org/W2509946779","https://openalex.org/W2568400148","https://openalex.org/W2625579868","https://openalex.org/W2809249901","https://openalex.org/W2893873030","https://openalex.org/W2894580221","https://openalex.org/W2990751432","https://openalex.org/W3015432522","https://openalex.org/W3111110024","https://openalex.org/W3116356442","https://openalex.org/W3130771274","https://openalex.org/W3190543560","https://openalex.org/W4281721869","https://openalex.org/W4288445433","https://openalex.org/W4313583836","https://openalex.org/W4319082087","https://openalex.org/W4362456017","https://openalex.org/W4367315496","https://openalex.org/W4386725936","https://openalex.org/W4387157385","https://openalex.org/W4388345842","https://openalex.org/W4391566469","https://openalex.org/W4401315089","https://openalex.org/W4403965828","https://openalex.org/W4408398415","https://openalex.org/W4411830572","https://openalex.org/W7123452202"],"related_works":["https://openalex.org/W7148989563","https://openalex.org/W4387157385","https://openalex.org/W4409690266","https://openalex.org/W4403965828","https://openalex.org/W7148779432","https://openalex.org/W4282979799","https://openalex.org/W2613270152","https://openalex.org/W2107879115","https://openalex.org/W2081728154","https://openalex.org/W2769171231"],"abstract_inverted_index":{"BACKGROUND:":[0],"Breast":[1],"cancer":[2,59,239],"remains":[3],"a":[4,12,141,213],"major":[5],"cause":[6],"of":[7,49,64,80,118,180,225,233],"cancer-related":[8],"mortality":[9],"worldwide,":[10],"creating":[11],"need":[13],"for":[14,25,84,228],"novel":[15],"therapeutic":[16],"strategies.":[17],"Natural":[18],"plant":[19],"compounds":[20,167],"have":[21],"gained":[22],"recent":[23],"attention":[24],"their":[26],"anticancer":[27],"effects,":[28],"including":[29],"oleuropein":[30,50],"from":[31,37],"olive":[32],"leaves,":[33],"and":[34,52,61,108,131,149,156,188,200,205,210,230],"punicic":[35,53],"acid":[36,54],"the":[38,42,47,62,217,231],"pomegranate":[39],"fruit.":[40],"In":[41],"present":[43],"study,":[44],"we":[45],"investigated":[46],"effects":[48,194],"(OL)":[51],"(PA)":[55],"on":[56],"MCF-7":[57,73,208],"breast":[58],"cells":[60,74],"role":[63,215],"peroxiredoxin":[65],"(Prdx)":[66],"antioxidants":[67],"in":[68,144,207,216,237],"mediating":[69],"these":[70,226],"effects.":[71],"METHODS:":[72],"were":[75],"treated":[76],"with":[77,136,153,158,191],"different":[78],"concentrations":[79],"OL":[81,137,187,199],"or":[82,138],"PA":[83,139,159,174,189,196,201],"72":[85],"h.":[86],"Viable":[87],"cell":[88,129,145,240],"density":[89],"was":[90,96,103,111,121],"measured":[91,97,104,112],"by":[92,98,105,113,123,128],"MTT":[93,132],"assay,":[94,107],"cytotoxicity":[95,206],"LDH":[99],"release,":[100],"mitochondrial":[101,170],"ROS":[102],"MitoSOX":[106],"lipid":[109,177],"peroxidation":[110],"MDA":[114],"assay.":[115,133],"The":[116],"effect":[117],"Prdx":[119,181],"suppression":[120],"determined":[122],"transient":[124],"siRNA":[125],"transfection,":[126],"followed":[127],"treatments":[130],"RESULTS:":[134],"Treatment":[135],"produced":[140],"concentration-dependent":[142],"reduction":[143],"viability,":[146],"increased":[147,169,183],"cytotoxicity,":[148],"morphological":[150],"changes":[151],"consistent":[152],"cellular":[154,184,218],"stress":[155,204],"death,":[157],"exhibiting":[160],"greater":[161],"potency":[162],"at":[163],"lower":[164],"concentrations.":[165],"Both":[166],"significantly":[168],"superoxide":[171],"production,":[172],"while":[173],"also":[175],"induced":[176],"peroxidation.":[178],"Suppression":[179],"proteins":[182],"susceptibility":[185],"to":[186],"treatment,":[190,229],"more":[192],"pronounced":[193],"following":[195],"exposure.":[197],"CONCLUSIONS:":[198],"induce":[202],"oxidative":[203],"cells,":[209],"peroxiredoxins":[211],"play":[212],"protective":[214],"response.":[219],"This":[220],"study":[221],"highlights":[222],"possible":[223],"efficacy":[224],"agents":[227],"importance":[232],"antioxidant":[234],"defense":[235],"systems":[236],"subsequent":[238],"survival.":[241]},"counts_by_year":[],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2026-11-02T00:00:00"}