{"id":"https://openalex.org/W7225015175","doi":"https://doi.org/10.2147/pgpm.s629435","title":"Anticancer Drugs Pharmacogenomics in African Populations: A Scoping Review of Clinico-Molecular Data and Involvement in Personalized Medicine","display_name":"Anticancer Drugs Pharmacogenomics in African Populations: A Scoping Review of Clinico-Molecular Data and Involvement in Personalized Medicine","publication_year":2026,"publication_date":"2026-10-31","ids":{"openalex":"https://openalex.org/W7225015175","doi":"https://doi.org/10.2147/pgpm.s629435","pmid":"https://pubmed.ncbi.nlm.nih.gov/42991678","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/13738218"},"language":"en","primary_location":{"id":"doi:10.2147/pgpm.s629435","doi":"https://doi.org/10.2147/pgpm.s629435","is_oa":true,"landing_page_url":"https://doi.org/10.2147/pgpm.s629435","pdf_url":"https://www.dovepress.com/article/download/121707","source":{"id":"https://openalex.org/S2764709116","display_name":"Pharmacogenomics and Personalized Medicine","issn_l":"1178-7066","issn":["1178-7066"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmacogenomics and Personalized Medicine","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.dovepress.com/article/download/121707","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5081681671","display_name":"Marc Donald Wilfried Adico","orcid":"https://orcid.org/0009-0002-3026-5651","observed_orcids":["https://orcid.org/0009-0002-3026-5651"]},"institutions":[{"id":"https://openalex.org/I129628643","display_name":"Universit\u00e9 Joseph Ki-Zerbo","ror":"https://ror.org/00t5e2y66","country_code":"BF","type":"education","lineage":["https://openalex.org/I129628643"]},{"id":"https://openalex.org/I4210126051","display_name":"Universit\u00e9 Pelefero Gon Coulibaly","ror":"https://ror.org/0358nsq19","country_code":"CI","type":"education","lineage":["https://openalex.org/I4210126051"]}],"countries":["BF","CI"],"is_corresponding":false,"raw_author_name":"Marc Donald Wilfried Adico","raw_affiliation_strings":["Department of Biochemistry-Microbiology, Laboratory of Molecular Biology and Molecular Genetics, Joseph KI-ZERBO University, Ouagadougou, Burkina Faso","Department of Genetics and Biochemistry, Peleforo GON COULIBALY University, Korhogo, C\u00f4te d'Ivoire","Department of Molecular Biology, Pietro Annigoni Biomolecular Research Center (CERBA), Ouagadougou, Burkina Faso"],"raw_orcid":"https://orcid.org/0009-0002-3026-5651","affiliations":[{"raw_affiliation_string":"Department of Biochemistry-Microbiology, Laboratory of Molecular Biology and Molecular Genetics, Joseph KI-ZERBO University, Ouagadougou, Burkina Faso","institution_ids":["https://openalex.org/I129628643"]},{"raw_affiliation_string":"Department of Genetics and Biochemistry, Peleforo GON COULIBALY University, Korhogo, C\u00f4te d'Ivoire","institution_ids":["https://openalex.org/I4210126051"]},{"raw_affiliation_string":"Department of Molecular Biology, Pietro Annigoni Biomolecular Research Center (CERBA), Ouagadougou, Burkina Faso","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016622673","display_name":"Tata Gnir\u00e9 Safiatou Coulibaly","orcid":"https://orcid.org/0000-0001-9398-9556","observed_orcids":["https://orcid.org/0000-0001-9398-9556"]},"institutions":[{"id":"https://openalex.org/I4210138991","display_name":"Institut Pasteur de C\u00f4te d'Ivoire","ror":"https://ror.org/046p4xa68","country_code":"CI","type":"nonprofit","lineage":["https://openalex.org/I4210138991"]}],"countries":["CI"],"is_corresponding":false,"raw_author_name":"Tata Gnire Safiatou Coulibaly","raw_affiliation_strings":["Molecular Genetics Platform, Pasteur Institute, Abidjan, C\u00f4te d'Ivoire"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Molecular Genetics Platform, Pasteur Institute, Abidjan, C\u00f4te d'Ivoire","institution_ids":["https://openalex.org/I4210138991"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024329091","display_name":"Dramane Dagnogo","orcid":"https://orcid.org/0000-0003-4113-8850","observed_orcids":["https://orcid.org/0000-0003-4113-8850"]},"institutions":[{"id":"https://openalex.org/I4210126051","display_name":"Universit\u00e9 Pelefero Gon Coulibaly","ror":"https://ror.org/0358nsq19","country_code":"CI","type":"education","lineage":["https://openalex.org/I4210126051"]}],"countries":["CI"],"is_corresponding":false,"raw_author_name":"Dramane Dagnogo","raw_affiliation_strings":["Department of Genetics and Biochemistry, Peleforo GON COULIBALY University, Korhogo, C\u00f4te d'Ivoire"],"raw_orcid":"https://orcid.org/0000-0003-4113-8850","affiliations":[{"raw_affiliation_string":"Department of Genetics and Biochemistry, Peleforo GON COULIBALY University, Korhogo, C\u00f4te d'Ivoire","institution_ids":["https://openalex.org/I4210126051"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109654407","display_name":"Mousso Savadogo","orcid":"https://orcid.org/0000-0001-5963-6618","observed_orcids":["https://orcid.org/0000-0001-5963-6618"]},"institutions":[{"id":"https://openalex.org/I129628643","display_name":"Universit\u00e9 Joseph Ki-Zerbo","ror":"https://ror.org/00t5e2y66","country_code":"BF","type":"education","lineage":["https://openalex.org/I129628643"]}],"countries":["BF"],"is_corresponding":false,"raw_author_name":"Mousso Savadogo","raw_affiliation_strings":["Department of Biochemistry-Microbiology, Laboratory of Molecular Biology and Molecular Genetics, Joseph KI-ZERBO University, Ouagadougou, Burkina Faso"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry-Microbiology, Laboratory of Molecular Biology and Molecular Genetics, Joseph KI-ZERBO University, Ouagadougou, Burkina Faso","institution_ids":["https://openalex.org/I129628643"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5129670072","display_name":"Marie Pierre Alimata Wentoin Daramcoum","orcid":"https://orcid.org/0009-0008-8604-9839","observed_orcids":["https://orcid.org/0009-0008-8604-9839"]},"institutions":[{"id":"https://openalex.org/I4210126051","display_name":"Universit\u00e9 Pelefero Gon Coulibaly","ror":"https://ror.org/0358nsq19","country_code":"CI","type":"education","lineage":["https://openalex.org/I4210126051"]}],"countries":["CI"],"is_corresponding":false,"raw_author_name":"Wentoin Alimata Marie Pierre Daramcoum","raw_affiliation_strings":["Department of Genetics and Biochemistry, African Center for Shea Research and Applications (CRAK), Laboratory of Molecular Biology and Functional Genomics (BIOGEN-CRAK), Peleforo GON COULIBALY University, Korhogo, C\u00f4te d'Ivoire","Department of Genetics and Biochemistry, Peleforo GON COULIBALY University, Korhogo, C\u00f4te d'Ivoire"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics and Biochemistry, African Center for Shea Research and Applications (CRAK), Laboratory of Molecular Biology and Functional Genomics (BIOGEN-CRAK), Peleforo GON COULIBALY University, Korhogo, C\u00f4te d'Ivoire","institution_ids":["https://openalex.org/I4210126051"]},{"raw_affiliation_string":"Department of Genetics and Biochemistry, Peleforo GON COULIBALY University, Korhogo, C\u00f4te d'Ivoire","institution_ids":["https://openalex.org/I4210126051"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047780022","display_name":"Yao Saraka Didier Martial","orcid":"https://orcid.org/0000-0003-4622-3317","observed_orcids":["https://orcid.org/0000-0003-4622-3317"]},"institutions":[{"id":"https://openalex.org/I4210126051","display_name":"Universit\u00e9 Pelefero Gon Coulibaly","ror":"https://ror.org/0358nsq19","country_code":"CI","type":"education","lineage":["https://openalex.org/I4210126051"]}],"countries":["CI"],"is_corresponding":false,"raw_author_name":"Saraka Didier Martial Yao","raw_affiliation_strings":["Department of Genetics and Biochemistry, African Center for Shea Research and Applications (CRAK), Laboratory of Molecular Biology and Functional Genomics (BIOGEN-CRAK), Peleforo GON COULIBALY University, Korhogo, C\u00f4te d'Ivoire","Department of Genetics and Biochemistry, Peleforo GON COULIBALY University, Korhogo, C\u00f4te d'Ivoire"],"raw_orcid":"https://orcid.org/0000-0003-4622-3317","affiliations":[{"raw_affiliation_string":"Department of Genetics and Biochemistry, African Center for Shea Research and Applications (CRAK), Laboratory of Molecular Biology and Functional Genomics (BIOGEN-CRAK), Peleforo GON COULIBALY University, Korhogo, C\u00f4te d'Ivoire","institution_ids":["https://openalex.org/I4210126051"]},{"raw_affiliation_string":"Department of Genetics and Biochemistry, Peleforo GON COULIBALY University, Korhogo, C\u00f4te d'Ivoire","institution_ids":["https://openalex.org/I4210126051"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050056472","display_name":"Dago Dougba No\u00ebl","orcid":"https://orcid.org/0000-0003-1517-054X","observed_orcids":["https://orcid.org/0000-0003-1517-054X"]},"institutions":[{"id":"https://openalex.org/I4210126051","display_name":"Universit\u00e9 Pelefero Gon Coulibaly","ror":"https://ror.org/0358nsq19","country_code":"CI","type":"education","lineage":["https://openalex.org/I4210126051"]}],"countries":["CI"],"is_corresponding":false,"raw_author_name":"Dougba Noel Dago","raw_affiliation_strings":["Department of Genetics and Biochemistry, African Center for Shea Research and Applications (CRAK), Laboratory of Molecular Biology and Functional Genomics (BIOGEN-CRAK), Peleforo GON COULIBALY University, Korhogo, C\u00f4te d'Ivoire","Department of Genetics and Biochemistry, Peleforo GON COULIBALY University, Korhogo, C\u00f4te d'Ivoire"],"raw_orcid":"https://orcid.org/0000-0003-1517-054X","affiliations":[{"raw_affiliation_string":"Department of Genetics and Biochemistry, African Center for Shea Research and Applications (CRAK), Laboratory of Molecular Biology and Functional Genomics (BIOGEN-CRAK), Peleforo GON COULIBALY University, Korhogo, C\u00f4te d'Ivoire","institution_ids":["https://openalex.org/I4210126051"]},{"raw_affiliation_string":"Department of Genetics and Biochemistry, Peleforo GON COULIBALY University, Korhogo, C\u00f4te d'Ivoire","institution_ids":["https://openalex.org/I4210126051"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110553885","display_name":"Foungotin Hamidou Coulibaly","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I48615539","display_name":"Universit\u00e9 F\u00e9lix Houphou\u00ebt-Boigny","ror":"https://ror.org/03haqmz43","country_code":"CI","type":"education","lineage":["https://openalex.org/I48615539"]}],"countries":["CI"],"is_corresponding":false,"raw_author_name":"Foungotin Hamidou Coulibaly","raw_affiliation_strings":["Department of Biotechnology and Food Safety, Felix Houphouet Boigny University, Abidjan, C\u00f4te d'Ivoire"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biotechnology and Food Safety, Felix Houphouet Boigny University, Abidjan, C\u00f4te d'Ivoire","institution_ids":["https://openalex.org/I48615539"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084901205","display_name":"Abdou Azaque Zour\u00e9","orcid":"https://orcid.org/0000-0002-9423-024X","observed_orcids":["https://orcid.org/0000-0002-9423-024X"]},"institutions":[{"id":"https://openalex.org/I4210126051","display_name":"Universit\u00e9 Pelefero Gon Coulibaly","ror":"https://ror.org/0358nsq19","country_code":"CI","type":"education","lineage":["https://openalex.org/I4210126051"]}],"countries":["CI"],"is_corresponding":true,"raw_author_name":"Abdou Azaque Zour\u00e9","raw_affiliation_strings":["Department of Biomedical and Public Health, Research Institute for Health Sciences, Ouagadougou, Burkina Faso","Department of Genetics and Biochemistry, Peleforo GON COULIBALY University, Korhogo, C\u00f4te d'Ivoire","Department of Molecular Biology, Pietro Annigoni Biomolecular Research Center (CERBA), Ouagadougou, Burkina Faso"],"raw_orcid":"https://orcid.org/0000-0002-9423-024X","affiliations":[{"raw_affiliation_string":"Department of Biomedical and Public Health, Research Institute for Health Sciences, Ouagadougou, Burkina Faso","institution_ids":[]},{"raw_affiliation_string":"Department of Genetics and Biochemistry, Peleforo GON COULIBALY University, Korhogo, C\u00f4te d'Ivoire","institution_ids":["https://openalex.org/I4210126051"]},{"raw_affiliation_string":"Department of Molecular Biology, Pietro Annigoni Biomolecular Research Center (CERBA), Ouagadougou, Burkina Faso","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065971270","display_name":"Bagora Bayala","orcid":"https://orcid.org/0000-0002-8158-4831","observed_orcids":["https://orcid.org/0000-0002-8158-4831"]},"institutions":[{"id":"https://openalex.org/I4210126051","display_name":"Universit\u00e9 Pelefero Gon Coulibaly","ror":"https://ror.org/0358nsq19","country_code":"CI","type":"education","lineage":["https://openalex.org/I4210126051"]}],"countries":["CI"],"is_corresponding":false,"raw_author_name":"Bagora Bayala","raw_affiliation_strings":["Department Biochemistry, Ecole Normale Superieure, Koudougou, Burkina Faso","Department of Genetics and Biochemistry, Peleforo GON COULIBALY University, Korhogo, C\u00f4te d'Ivoire","Department of Molecular Biology, Pietro Annigoni Biomolecular Research Center (CERBA), Ouagadougou, Burkina Faso"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department Biochemistry, Ecole Normale Superieure, Koudougou, Burkina Faso","institution_ids":[]},{"raw_affiliation_string":"Department of Genetics and Biochemistry, Peleforo GON COULIBALY University, Korhogo, C\u00f4te d'Ivoire","institution_ids":["https://openalex.org/I4210126051"]},{"raw_affiliation_string":"Department of Molecular Biology, Pietro Annigoni Biomolecular Research Center (CERBA), Ouagadougou, Burkina Faso","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160243878","display_name":"Nafan Diarrassouba","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210126051","display_name":"Universit\u00e9 Pelefero Gon Coulibaly","ror":"https://ror.org/0358nsq19","country_code":"CI","type":"education","lineage":["https://openalex.org/I4210126051"]}],"countries":["CI"],"is_corresponding":false,"raw_author_name":"Nafan Diarrassouba","raw_affiliation_strings":["Department of Genetics and Biochemistry, African Center for Shea Research and Applications (CRAK), Laboratory of Molecular Biology and Functional Genomics (BIOGEN-CRAK), Peleforo GON COULIBALY University, Korhogo, C\u00f4te d'Ivoire","Department of Genetics and Biochemistry, Peleforo GON COULIBALY University, Korhogo, C\u00f4te d'Ivoire"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics and Biochemistry, African Center for Shea Research and Applications (CRAK), Laboratory of Molecular Biology and Functional Genomics (BIOGEN-CRAK), Peleforo GON COULIBALY University, Korhogo, C\u00f4te d'Ivoire","institution_ids":["https://openalex.org/I4210126051"]},{"raw_affiliation_string":"Department of Genetics and Biochemistry, Peleforo GON COULIBALY University, Korhogo, C\u00f4te d'Ivoire","institution_ids":["https://openalex.org/I4210126051"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046475816","display_name":"Florencia Wendkuuni Djigma","orcid":"https://orcid.org/0000-0002-6895-6725","observed_orcids":["https://orcid.org/0000-0002-6895-6725"]},"institutions":[{"id":"https://openalex.org/I129628643","display_name":"Universit\u00e9 Joseph Ki-Zerbo","ror":"https://ror.org/00t5e2y66","country_code":"BF","type":"education","lineage":["https://openalex.org/I129628643"]}],"countries":["BF"],"is_corresponding":false,"raw_author_name":"Wendkuuni Florencia Djigma","raw_affiliation_strings":["Department of Biochemistry-Microbiology, Laboratory of Molecular Biology and Molecular Genetics, Joseph KI-ZERBO University, Ouagadougou, Burkina Faso","Department of Molecular Biology, Pietro Annigoni Biomolecular Research Center (CERBA), Ouagadougou, Burkina Faso"],"raw_orcid":"https://orcid.org/0000-0002-6895-6725","affiliations":[{"raw_affiliation_string":"Department of Biochemistry-Microbiology, Laboratory of Molecular Biology and Molecular Genetics, Joseph KI-ZERBO University, Ouagadougou, Burkina Faso","institution_ids":["https://openalex.org/I129628643"]},{"raw_affiliation_string":"Department of Molecular Biology, Pietro Annigoni Biomolecular Research Center (CERBA), Ouagadougou, Burkina Faso","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5016256456","display_name":"Jacques Simpor\u00e8","orcid":"https://orcid.org/0000-0002-0415-9161","observed_orcids":["https://orcid.org/0000-0002-0415-9161"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jacques Simpor\u00e9","raw_affiliation_strings":["Department of Molecular Biology, Pietro Annigoni Biomolecular Research Center (CERBA), Ouagadougou, Burkina Faso"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biology, Pietro Annigoni Biomolecular Research Center (CERBA), Ouagadougou, Burkina Faso","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5084901205"],"corresponding_institution_ids":["https://openalex.org/I4210126051"],"apc_list":{"value":2836,"currency":"USD","value_usd":2836},"apc_paid":{"value":2836,"currency":"USD","value_usd":2836},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.61125654,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"Volume 19","issue":null,"first_page":"1","last_page":"22"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13984","display_name":"Nutrition, Genetics, and Disease","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pharmacogenomics","display_name":"pharmacogenomics","score":0.9860000014305115},{"id":"https://openalex.org/keywords/anticancer-agents","display_name":"anticancer agents","score":0.9879999756813049},{"id":"https://openalex.org/keywords/african-populations","display_name":"African populations","score":0.9419999718666077},{"id":"https://openalex.org/keywords/personalized-medicine","display_name":"personalized medicine","score":0.9490000009536743},{"id":"https://openalex.org/keywords/genetic-variants","display_name":"genetic variants","score":0.7269999980926514},{"id":"https://openalex.org/keywords/drug-efficacy","display_name":"drug efficacy","score":0.6119999885559082},{"id":"https://openalex.org/keywords/drug-toxicity","display_name":"drug toxicity","score":0.9829999804496765},{"id":"https://openalex.org/keywords/p-glycoprotein","display_name":"P-glycoprotein","score":0.8259999752044678},{"id":"https://openalex.org/keywords/cyp3a5","display_name":"CYP3A5","score":0.9599999785423279},{"id":"https://openalex.org/keywords/cyp2d6","display_name":"CYP2D6","score":0.9909999966621399},{"id":"https://openalex.org/keywords/slc28a3","display_name":"SLC28A3","score":0.9179999828338623},{"id":"https://openalex.org/keywords/cyp2c9","display_name":"CYP2C9","score":0.9860000014305115},{"id":"https://openalex.org/keywords/cyp2b6","display_name":"CYP2B6","score":0.9980000257492065},{"id":"https://openalex.org/keywords/thiopurine-methyltransferase","display_name":"thiopurine S-methyltransferase","score":0.9959999918937683},{"id":"https://openalex.org/keywords/mthfr","display_name":"MTHFR","score":0.9980000257492065},{"id":"https://openalex.org/keywords/imatinib","display_name":"imatinib","score":0.9359999895095825},{"id":"https://openalex.org/keywords/tamoxifen","display_name":"tamoxifen","score":0.9990000128746033},{"id":"https://openalex.org/keywords/doxorubicin","display_name":"doxorubicin","score":0.9990000128746033},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.8299999833106995},{"id":"https://openalex.org/keywords/chronic-myeloid-leukemia","display_name":"chronic myeloid leukemia","score":0.996999979019165},{"id":"https://openalex.org/keywords/acute-lymphoblastic-leukemia","display_name":"acute lymphoblastic leukemia","score":0.9990000128746033},{"id":"https://openalex.org/keywords/anticancer-drug-response","display_name":"anticancer drug response","score":0.3440000116825104},{"id":"https://openalex.org/keywords/research-gap","display_name":"research gaps","score":0.6019999980926514},{"id":"https://openalex.org/keywords/geographic-disparities","display_name":"geographic disparities","score":0.30799999833106995}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.960099995136261},{"id":"https://openalex.org/C170734499","wikidata":"https://www.wikidata.org/wiki/Q1152227","display_name":"Pharmacogenomics","level":2,"score":0.8758000135421753},{"id":"https://openalex.org/C32220436","wikidata":"https://www.wikidata.org/wiki/Q2072214","display_name":"Personalized medicine","level":2,"score":0.7713000178337097},{"id":"https://openalex.org/C163763905","wikidata":"https://www.wikidata.org/wiki/Q17075943","display_name":"Precision medicine","level":2,"score":0.5781999826431274},{"id":"https://openalex.org/C55775858","wikidata":"https://www.wikidata.org/wiki/Q1152227","display_name":"Pharmacogenetics","level":4,"score":0.49149999022483826},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.4796000123023987},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.41830000281333923},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.40130001306533813},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3646000027656555},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.35089999437332153},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.2955999970436096},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2867000102996826},{"id":"https://openalex.org/C2994119904","wikidata":"https://www.wikidata.org/wiki/Q1251001","display_name":"Drug response","level":3,"score":0.2590000033378601},{"id":"https://openalex.org/C3018822202","wikidata":"https://www.wikidata.org/wiki/Q1324077","display_name":"Patient data","level":2,"score":0.2551000118255615}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.2147/pgpm.s629435","doi":"https://doi.org/10.2147/pgpm.s629435","is_oa":true,"landing_page_url":"https://doi.org/10.2147/pgpm.s629435","pdf_url":"https://www.dovepress.com/article/download/121707","source":{"id":"https://openalex.org/S2764709116","display_name":"Pharmacogenomics and Personalized Medicine","issn_l":"1178-7066","issn":["1178-7066"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmacogenomics and Personalized Medicine","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13738218","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13738218/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13738218/pdf/PGPM-19-629435.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmgenomics Pers Med","raw_type":"Text"},{"id":"pmid:42991678","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42991678","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmacogenomics and personalized medicine","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:75c013a8208543b4b6f39b5258cbc3a4","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/75c013a8208543b4b6f39b5258cbc3a4","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Pharmacogenomics and Personalized Medicine, Vol Volume 19, Iss Issue 1, Pp 1-22 (2026)","raw_type":"article"},{"id":"pmh:oai:dovepress.com/121707","doi":null,"is_oa":true,"landing_page_url":"https://www.dovepress.com/anticancer-drugs-pharmacogenomics-in-african-populations-a-scoping-rev-peer-reviewed-fulltext-article-PGPM","pdf_url":null,"source":{"id":"https://openalex.org/S4306401012","display_name":"Dove Medical Press (Taylor and Francis Group)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Review"}],"best_oa_location":{"id":"doi:10.2147/pgpm.s629435","doi":"https://doi.org/10.2147/pgpm.s629435","is_oa":true,"landing_page_url":"https://doi.org/10.2147/pgpm.s629435","pdf_url":"https://www.dovepress.com/article/download/121707","source":{"id":"https://openalex.org/S2764709116","display_name":"Pharmacogenomics and Personalized Medicine","issn_l":"1178-7066","issn":["1178-7066"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmacogenomics and Personalized Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/systematic-review","display_name":"Systematic Review"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7225015175.pdf","grobid_xml":"https://content.openalex.org/works/W7225015175.grobid-xml"},"referenced_works_count":76,"referenced_works":["https://openalex.org/W1068268492","https://openalex.org/W1968857592","https://openalex.org/W1979703911","https://openalex.org/W2057855795","https://openalex.org/W2077522929","https://openalex.org/W2078361182","https://openalex.org/W2090817779","https://openalex.org/W2100096823","https://openalex.org/W2104243204","https://openalex.org/W2108636446","https://openalex.org/W2111662961","https://openalex.org/W2132157071","https://openalex.org/W2137253585","https://openalex.org/W2142037478","https://openalex.org/W2144360398","https://openalex.org/W2209793613","https://openalex.org/W2252852588","https://openalex.org/W2352491315","https://openalex.org/W2385169442","https://openalex.org/W2490170146","https://openalex.org/W2493479489","https://openalex.org/W2520242613","https://openalex.org/W2536495322","https://openalex.org/W2592059103","https://openalex.org/W2747419560","https://openalex.org/W2767799232","https://openalex.org/W2789470442","https://openalex.org/W2792046032","https://openalex.org/W2792944991","https://openalex.org/W2799958772","https://openalex.org/W2912095266","https://openalex.org/W2955744231","https://openalex.org/W2981329862","https://openalex.org/W2983359295","https://openalex.org/W3009183131","https://openalex.org/W3019516845","https://openalex.org/W3033683362","https://openalex.org/W3081634328","https://openalex.org/W3097237895","https://openalex.org/W3163271892","https://openalex.org/W3164736191","https://openalex.org/W3168991095","https://openalex.org/W4206841660","https://openalex.org/W4224213575","https://openalex.org/W4224981845","https://openalex.org/W4231349869","https://openalex.org/W4280570369","https://openalex.org/W4295279253","https://openalex.org/W4311669463","https://openalex.org/W4313453889","https://openalex.org/W4315620077","https://openalex.org/W4317733597","https://openalex.org/W4318778061","https://openalex.org/W4327573035","https://openalex.org/W4378746368","https://openalex.org/W4381309074","https://openalex.org/W4392017709","https://openalex.org/W4392673836","https://openalex.org/W4392879171","https://openalex.org/W4400749063","https://openalex.org/W4401062498","https://openalex.org/W4401868887","https://openalex.org/W4403073139","https://openalex.org/W4406772166","https://openalex.org/W4406867792","https://openalex.org/W4407527419","https://openalex.org/W4407773438","https://openalex.org/W4408453900","https://openalex.org/W4409895770","https://openalex.org/W4412073366","https://openalex.org/W4416371057","https://openalex.org/W7125975838","https://openalex.org/W7126246780","https://openalex.org/W7127592520","https://openalex.org/W7149927221","https://openalex.org/W7153041201"],"related_works":["https://openalex.org/W3009183131","https://openalex.org/W2799870154","https://openalex.org/W2470828299","https://openalex.org/W7160284037","https://openalex.org/W7204047091","https://openalex.org/W2477539825","https://openalex.org/W7005050507","https://openalex.org/W4391593103","https://openalex.org/W2016735858","https://openalex.org/W2600673420"],"abstract_inverted_index":{"In":[0,33],"recent":[1],"decades,":[2],"Africa":[3],"has":[4],"experienced":[5],"an":[6,365],"increase":[7],"in":[8,42,48,59,91,127,193,212,258,302,354,373,379,393],"cancer":[9,149,342,358,394],"mortality":[10],"rates.":[11],"This":[12,116,164,362],"challenge":[13],"conducted":[14,119],"to":[15,70,105,121,168,221,346],"wide":[16],"use":[17],"of":[18,65,79,88,154,172,177,188,215,224,237,260,299,335,351,357,367,376],"anticancer":[19,89,178,309,377],"drugs":[20,90,179,301,310,343,378],"but":[21],"their":[22,181,312],"efficacy":[23,84,296],"and":[24,44,73,85,100,113,124,139,157,180,200,271,282,297,318,325,371,389],"toxicity":[25,87,298],"may":[26,37],"vary":[27],"depending":[28],"on":[29,82,146,160,174,359,396],"patient's":[30],"genetic":[31,80],"characteristics.":[32],"this":[34,60,66,238],"context,":[35],"pharmacogenomics":[36],"play":[38],"a":[39,255,265,348],"crucial":[40],"role":[41],"optimizing":[43],"personalizing":[45],"these":[46,241],"treatments":[47],"African":[49,92,398],"populations,":[50],"which":[51,216],"have":[52,285,329],"been":[53,286,330],"very":[54],"little":[55],"studied":[56,333],"so":[57],"far":[58],"field.":[61],"The":[62,94,252,274,305,337],"main":[63],"objective":[64],"scoping":[67],"review":[68,117],"is":[69,382],"identify":[71],"clinical":[72,158],"molecular":[74],"data":[75,340],"concerning":[76],"the":[77,83,86,122,130,170,175,194,222,225,234,261,287,295,331,355,360,368,397],"influence":[78],"variants":[81,245],"populations.":[93],"scientific":[95],"databases":[96],"PubMed,":[97],"Science":[98],"Direct,":[99],"Google":[101],"Scholar":[102],"were":[103,162,191,205,210,218,231,250,291],"used":[104,167],"search":[106],"for":[107,136,142,183,233,311,341,385],"articles":[108,190,204,230],"published":[109],"between":[110],"January":[111],"2010":[112],"December":[114],"2025.":[115],"was":[118,166],"according":[120],"Arksey":[123],"O'Malley":[125],"framework":[126],"accordance":[128],"with":[129,264,294],"PRISMA-ScR":[131],"method":[132],"(Preferred":[133],"Reporting":[134],"Items":[135],"Systematic":[137],"Reviews":[138],"Meta-Analyses":[140],"extension":[141],"Scoping":[143],"Reviews).":[144],"Data":[145],"genes,":[147],"variants,":[148],"type,":[150],"drug,":[151],"country,":[152],"year":[153],"study":[155,363],"publication,":[156],"effects":[159],"patients":[161],"extracted.":[163],"information":[165],"highlight":[169],"effect":[171],"pharmacogenes":[173],"response":[176],"implication":[182],"personalized":[184,352],"medicine.":[185],"A":[186],"total":[187],"2397":[189],"identified":[192],"three":[195],"databases.":[196],"After":[197],"eliminating":[198],"duplicates":[199],"off-topic":[201],"articles,":[202,243],"59":[203],"selected.":[206],"Among":[207],"them,":[208],"30":[209],"examined":[211],"full":[213,226],"text,":[214],"two":[217],"excluded":[219],"due":[220],"unavailability":[223],"text.":[227],"Finally,":[228],"28":[229,242],"selected":[232],"qualitative":[235],"analysis":[236],"review.":[239],"From":[240],"58":[244],"spread":[246],"over":[247],"41":[248],"genes":[249,284],"identified.":[251],"results":[253],"revealed":[254],"geographical":[256],"disparity":[257],"importance":[259],"included":[262],"research,":[263],"strong":[266],"one":[267],"coming":[268],"from":[269],"North":[270],"Southern":[272],"Africa.":[273,380],"ABCB1,":[275],"CYP3A5,":[276],"CYP2D6,":[277],"SLC28A3,":[278],"CYP2C9,":[279],"CYP2B6,":[280],"TPMT":[281],"MTHFR":[283],"most":[288,303,306,332],"studied.":[289],"They":[290],"significantly":[292],"associated":[293],"chemotherapeutic":[300],"studies.":[304],"frequently":[307],"analyzed":[308],"drug-gene":[313],"associations":[314],"include":[315],"imatinib,":[316],"tamoxifen":[317],"doxorubicin.":[319],"Breast":[320],"cancer,":[321],"chronic":[322],"myeloid":[323],"leukemia":[324,328],"acute":[326],"lymphoblastic":[327],"types":[334],"cancer.":[336],"available":[338],"pharmacogenomic":[339,374],"remain":[344],"insufficient":[345],"allow":[347],"real":[349],"application":[350],"medicine":[353],"treatment":[356],"continent.":[361,399],"provides":[364],"overview":[366],"current":[369],"state":[370],"gaps":[372],"research":[375],"It":[381],"particularly":[383],"intended":[384],"pharmacologic":[386],"clinicians,":[387],"oncologists":[388],"health":[390],"decision-makers":[391],"involved":[392],"management":[395]},"counts_by_year":[],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2026-11-01T00:00:00"}