{"id":"https://openalex.org/W7224923331","doi":"https://doi.org/10.1038/s41598-026-78232-8","title":"Eye-state-dependent reorganization of EEG microstates in a pediatric transdiagnostic cohort","display_name":"Eye-state-dependent reorganization of EEG microstates in a pediatric transdiagnostic cohort","publication_year":2026,"publication_date":"2026-10-30","ids":{"openalex":"https://openalex.org/W7224923331","doi":"https://doi.org/10.1038/s41598-026-78232-8"},"language":"en","primary_location":{"id":"doi:10.1038/s41598-026-78232-8","doi":"https://doi.org/10.1038/s41598-026-78232-8","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-026-78232-8","pdf_url":"https://www.nature.com/articles/s41598-026-78232-8_reference.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41598-026-78232-8_reference.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5160233421","display_name":"Ou Xu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210162133","display_name":"Hangzhou Children's Hospital","ror":"https://ror.org/05dfe8p27","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210162133"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ou Xu","raw_affiliation_strings":["Hangzhou Childrens Hospital, Hangzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hangzhou Childrens Hospital, Hangzhou, China","institution_ids":["https://openalex.org/I4210162133"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5160188900","display_name":"Xiaoyan Sun","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Xiaoyan Sun","raw_affiliation_strings":["Jiaxing Maternity and Child Health Care Hospital, Jiaxing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Jiaxing Maternity and Child Health Care Hospital, Jiaxing, China","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5160188900"],"corresponding_institution_ids":[],"apc_list":{"value":2690,"currency":"USD","value_usd":2690},"apc_paid":{"value":2690,"currency":"USD","value_usd":2690},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.82701961,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.5679000020027161,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.5679000020027161,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.24070000648498535,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10429","display_name":"EEG and Brain-Computer Interfaces","score":0.13369999825954437,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/eeg-microstates","display_name":"EEG microstates","score":0.9950000047683716},{"id":"https://openalex.org/keywords/eye-state","display_name":"eye state","score":0.6079999804496765},{"id":"https://openalex.org/keywords/pediatric-eeg","display_name":"pediatric EEG","score":0.5680000185966492},{"id":"https://openalex.org/keywords/resting-state-eeg","display_name":"resting-state EEG","score":0.5600000023841858},{"id":"https://openalex.org/keywords/attention-deficit-hyperactivity-disorder","display_name":"attention deficit hyperactivity disorder","score":0.5730000138282776},{"id":"https://openalex.org/keywords/childhood-anxiety","display_name":"childhood anxiety","score":0.7639999985694885},{"id":"https://openalex.org/keywords/healthy-brain-network","display_name":"Healthy Brain Network","score":0.6499999761581421}],"concepts":[{"id":"https://openalex.org/C45424060","wikidata":"https://www.wikidata.org/wiki/Q244381","display_name":"Ministate","level":3,"score":0.901199996471405},{"id":"https://openalex.org/C522805319","wikidata":"https://www.wikidata.org/wiki/Q179965","display_name":"Electroencephalography","level":2,"score":0.6442000269889832},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.5468000173568726},{"id":"https://openalex.org/C548259974","wikidata":"https://www.wikidata.org/wiki/Q569965","display_name":"Audiology","level":1,"score":0.4867999851703644},{"id":"https://openalex.org/C141516989","wikidata":"https://www.wikidata.org/wiki/Q1182555","display_name":"Default mode network","level":3,"score":0.4620000123977661},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.44440001249313354},{"id":"https://openalex.org/C142853389","wikidata":"https://www.wikidata.org/wiki/Q744778","display_name":"Association (psychology)","level":2,"score":0.41589999198913574},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.398499995470047},{"id":"https://openalex.org/C112758219","wikidata":"https://www.wikidata.org/wiki/Q16038819","display_name":"Duration (music)","level":2,"score":0.38119998574256897},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.36329999566078186},{"id":"https://openalex.org/C66324658","wikidata":"https://www.wikidata.org/wiki/Q7316120","display_name":"Resting state fMRI","level":2,"score":0.35019999742507935},{"id":"https://openalex.org/C64943373","wikidata":"https://www.wikidata.org/wiki/Q2651003","display_name":"Alpha (finance)","level":4,"score":0.3407000005245209},{"id":"https://openalex.org/C50231774","wikidata":"https://www.wikidata.org/wiki/Q639842","display_name":"Brain mapping","level":2,"score":0.3319999873638153},{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.29789999127388},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.28929999470710754},{"id":"https://openalex.org/C2776502983","wikidata":"https://www.wikidata.org/wiki/Q690182","display_name":"Contrast (vision)","level":2,"score":0.2596000134944916},{"id":"https://openalex.org/C58693492","wikidata":"https://www.wikidata.org/wiki/Q551875","display_name":"Neuroimaging","level":2,"score":0.25609999895095825},{"id":"https://openalex.org/C120843803","wikidata":"https://www.wikidata.org/wiki/Q4955807","display_name":"Brain activity and meditation","level":3,"score":0.2531000077724457}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1038/s41598-026-78232-8","doi":"https://doi.org/10.1038/s41598-026-78232-8","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-026-78232-8","pdf_url":"https://www.nature.com/articles/s41598-026-78232-8_reference.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1038/s41598-026-78232-8","doi":"https://doi.org/10.1038/s41598-026-78232-8","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-026-78232-8","pdf_url":"https://www.nature.com/articles/s41598-026-78232-8_reference.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7224923331.pdf","grobid_xml":"https://content.openalex.org/works/W7224923331.grobid-xml"},"referenced_works_count":1,"referenced_works":["https://openalex.org/W7154025526"],"related_works":["https://openalex.org/W4387893716","https://openalex.org/W4285045624","https://openalex.org/W4304148421","https://openalex.org/W4406261624","https://openalex.org/W4220847896","https://openalex.org/W2414852983","https://openalex.org/W7015409945","https://openalex.org/W4291515304","https://openalex.org/W7203647238","https://openalex.org/W2054655287"],"abstract_inverted_index":{"Abstract":[0],"Resting":[1],"electroencephalography":[2],"(EEG)":[3],"is":[4],"sensitive":[5],"to":[6],"eye":[7,181],"condition,":[8,182],"yet":[9],"the":[10,35,65,120,124],"reorganization":[11],"of":[12,49,67],"pediatric":[13],"EEG":[14],"microstates":[15],"between":[16,134],"eyes-closed":[17],"(EC)":[18],"and":[19,28,46,54,61,74,96,99,111,129,138,143,178,187,197],"eyes-open":[20],"(EO)":[21],"rest":[22],"remains":[23],"incompletely":[24],"characterized.":[25],"Paired":[26],"EC":[27],"EO":[29],"recordings":[30],"from":[31,77],"110":[32],"children":[33],"in":[34,141,195],"Healthy":[36],"Brain":[37],"Network":[38],"were":[39],"analyzed":[40,188],"using":[41],"polarity-invariant":[42],"two-level":[43],"clustering,":[44],"backfitting,":[45],"within-participant":[47],"tests":[48],"microstate":[50,160,172],"duration,":[51],"coverage,":[52],"occurrence,":[53],"transition":[55],"measures.":[56],"Eye":[57],"opening":[58],"shortened":[59],"A":[60,148],"C":[62,78],"segments,":[63],"increased":[64],"occurrence":[66],"all":[68],"four":[69],"K":[70,84,107,151,168],"=":[71,85,108,152,169],"4":[72,86,153],"classes,":[73],"redistributed":[75],"coverage":[76],"toward":[79],"B.":[80],"All":[81],"eight":[82],"significant":[83],"temporal":[87,185],"effects":[88],"retained":[89],"their":[90],"direction":[91,144],"after":[92],"participant-wise":[93],"duration":[94,189],"matching":[95],"template":[97],"re-estimation,":[98],"broad":[100],"state":[101],"sensitivity":[102],"was":[103],"also":[104],"observed":[105],"at":[106,167],"6.":[109,170],"Change-score":[110],"baseline-adjusted":[112],"analyses":[113],"yielded":[114],"comparable":[115],"EC-to-EO":[116],"response":[117],"profiles":[118],"among":[119],"comparison":[121],"group":[122],"without":[123],"target":[125],"diagnoses,":[126],"ADHD-only":[127],"group,":[128],"ADHD+Anxiety":[130],"group.":[131],"The":[132],"association":[133],"posterior":[135],"alpha":[136],"reactivity":[137],"switching":[139],"varied":[140],"magnitude":[142],"across":[145],"segmentation":[146],"specifications.":[147],"stable":[149],"fourth":[150],"map":[154,165],"showed":[155],"little":[156],"correspondence":[157],"with":[158],"adult":[159],"D,":[161],"whereas":[162],"a":[163],"D-like":[164],"emerged":[166],"Pediatric":[171],"measures":[173],"reflect":[174],"both":[175],"physiological":[176],"context":[177],"analytical":[179],"definition;":[180],"model":[183],"order,":[184],"smoothing,":[186],"should":[190],"therefore":[191],"be":[192],"specified":[193],"explicitly":[194],"developmental":[196],"clinical":[198],"studies.":[199]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-10-31T00:00:00"}