{"id":"https://openalex.org/W7224910297","doi":"https://doi.org/10.21182/jmisst.2026.03853","title":"Comparative Outcomes of Cement-Augmented Fenestrated and Conventional Pedicle Screws in Transforaminal Lumbar Interbody Fusion: A Matched Cohort Study","display_name":"Comparative Outcomes of Cement-Augmented Fenestrated and Conventional Pedicle Screws in Transforaminal Lumbar Interbody Fusion: A Matched Cohort Study","publication_year":2026,"publication_date":"2026-10-30","ids":{"openalex":"https://openalex.org/W7224910297","doi":"https://doi.org/10.21182/jmisst.2026.03853"},"language":"en","primary_location":{"id":"doi:10.21182/jmisst.2026.03853","doi":"https://doi.org/10.21182/jmisst.2026.03853","is_oa":true,"landing_page_url":"https://doi.org/10.21182/jmisst.2026.03853","pdf_url":"https://www.jmisst.org/upload/pdf/jmisst-2026-03853.pdf","source":{"id":"https://openalex.org/S4210227605","display_name":"Journal of Minimally Invasive Spine Surgery and Technique","issn_l":"2508-2043","issn":["2508-2043"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Minimally Invasive Spine Surgery and Technique","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.jmisst.org/upload/pdf/jmisst-2026-03853.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5160170809","display_name":"Tan Xin En","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1291357265","display_name":"Ministry of Health","ror":"https://ror.org/00mrhvv69","country_code":"SG","type":"government","lineage":["https://openalex.org/I1291357265"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Tan Xin En","raw_affiliation_strings":["Ministry of Health Holdings, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ministry of Health Holdings, Singapore","institution_ids":["https://openalex.org/I1291357265"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034506491","display_name":"Reuben Chee Cheong Soh","orcid":"https://orcid.org/0000-0003-2410-5176","observed_orcids":["https://orcid.org/0000-0003-2410-5176"]},"institutions":[{"id":"https://openalex.org/I2251586001","display_name":"Singapore General Hospital","ror":"https://ror.org/036j6sg82","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I2251586001"]}],"countries":["SG"],"is_corresponding":true,"raw_author_name":"Reuben C.C. Soh","raw_affiliation_strings":["Department of Orthopaedic Surgery, Singapore General Hospital, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedic Surgery, Singapore General Hospital, Singapore","institution_ids":["https://openalex.org/I2251586001"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029372692","display_name":"Graham Seow-Hng Goh","orcid":"https://orcid.org/0000-0002-7337-3321","observed_orcids":["https://orcid.org/0000-0002-7337-3321"]},"institutions":[{"id":"https://openalex.org/I2251586001","display_name":"Singapore General Hospital","ror":"https://ror.org/036j6sg82","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I2251586001"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Graham S. Goh","raw_affiliation_strings":["Department of Orthopaedic Surgery, Singapore General Hospital, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedic Surgery, Singapore General Hospital, Singapore","institution_ids":["https://openalex.org/I2251586001"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008120298","display_name":"Gerald Joseph Zeng","orcid":"https://orcid.org/0000-0002-2559-6168","observed_orcids":["https://orcid.org/0000-0002-2559-6168"]},"institutions":[{"id":"https://openalex.org/I2251586001","display_name":"Singapore General Hospital","ror":"https://ror.org/036j6sg82","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I2251586001"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Gerald J. Zeng","raw_affiliation_strings":["Department of Orthopaedic Surgery, Singapore General Hospital, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedic Surgery, Singapore General Hospital, Singapore","institution_ids":["https://openalex.org/I2251586001"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5126951650","display_name":"Jiang Lei","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2251586001","display_name":"Singapore General Hospital","ror":"https://ror.org/036j6sg82","country_code":"SG","type":"healthcare","lineage":["https://openalex.org/I2251586001"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Jiang Lei","raw_affiliation_strings":["Department of Orthopaedic Surgery, Singapore General Hospital, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedic Surgery, Singapore General Hospital, Singapore","institution_ids":["https://openalex.org/I2251586001"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5005384323","display_name":"Wongthawat Liawrungrueang","orcid":"https://orcid.org/0000-0002-4491-6569","observed_orcids":["https://orcid.org/0000-0002-4491-6569"]},"institutions":[{"id":"https://openalex.org/I4210090662","display_name":"University of Phayao","ror":"https://ror.org/00a5mh069","country_code":"TH","type":"education","lineage":["https://openalex.org/I4210090662"]}],"countries":["TH"],"is_corresponding":true,"raw_author_name":"Wongthawat Liawrungrueang","raw_affiliation_strings":["Department of Orthopaedics, School of Medicine, University of Phayao, Phayao, Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedics, School of Medicine, University of Phayao, Phayao, Thailand","institution_ids":["https://openalex.org/I4210090662"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5005384323","https://openalex.org/A5034506491"],"corresponding_institution_ids":["https://openalex.org/I2251586001","https://openalex.org/I4210090662"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.86810195,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"11","issue":"2","first_page":"293","last_page":"302"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10238","display_name":"Spine and Intervertebral Disc Pathology","score":0.9291999936103821,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10238","display_name":"Spine and Intervertebral Disc Pathology","score":0.9291999936103821,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10776","display_name":"Spinal Fractures and Fixation Techniques","score":0.06549999862909317,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11518","display_name":"Cervical and Thoracic Myelopathy","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/transforaminal-lumbar-interbody-fusion","display_name":"transforaminal lumbar interbody fusion","score":0.9760000109672546},{"id":"https://openalex.org/keywords/bone-cement-augmentation","display_name":"bone cement augmentation","score":0.6230000257492065},{"id":"https://openalex.org/keywords/osteoporosis","display_name":"osteoporosis","score":0.7829999923706055},{"id":"https://openalex.org/keywords/osteopenia","display_name":"osteopenia","score":0.9570000171661377},{"id":"https://openalex.org/keywords/degenerative-spinal-stenosis","display_name":"degenerative spinal stenosis","score":0.8840000033378601},{"id":"https://openalex.org/keywords/spinal-instability","display_name":"spinal instability","score":0.7720000147819519},{"id":"https://openalex.org/keywords/radicular-symptoms","display_name":"radicular symptoms","score":0.8140000104904175},{"id":"https://openalex.org/keywords/interbody-fusion-rate","display_name":"interbody fusion rate","score":0.7400000095367432},{"id":"https://openalex.org/keywords/postoperative-opioid-consumption","display_name":"postoperative opioid use","score":0.8270000219345093},{"id":"https://openalex.org/keywords/patient-reported-outcomes","display_name":"patient-reported outcomes","score":0.9330000281333923},{"id":"https://openalex.org/keywords/operative-time","display_name":"operative time","score":0.5040000081062317}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.984000027179718},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.7527999877929688},{"id":"https://openalex.org/C31174226","wikidata":"https://www.wikidata.org/wiki/Q64855140","display_name":"Perioperative","level":2,"score":0.6029999852180481},{"id":"https://openalex.org/C2775998654","wikidata":"https://www.wikidata.org/wiki/Q11751687","display_name":"Oswestry Disability Index","level":4,"score":0.5946000218391418},{"id":"https://openalex.org/C14184104","wikidata":"https://www.wikidata.org/wiki/Q1362526","display_name":"Visual analogue scale","level":2,"score":0.5113999843597412},{"id":"https://openalex.org/C36454342","wikidata":"https://www.wikidata.org/wiki/Q245341","display_name":"Radiography","level":2,"score":0.4925000071525574},{"id":"https://openalex.org/C2780175798","wikidata":"https://www.wikidata.org/wiki/Q1478321","display_name":"Spinal stenosis","level":3,"score":0.49070000648498535},{"id":"https://openalex.org/C2779631646","wikidata":"https://www.wikidata.org/wiki/Q17164695","display_name":"Lumbar spinal stenosis","level":3,"score":0.3905999958515167},{"id":"https://openalex.org/C2780375110","wikidata":"https://www.wikidata.org/wiki/Q770609","display_name":"Spinal fusion","level":2,"score":0.38510000705718994},{"id":"https://openalex.org/C44575665","wikidata":"https://www.wikidata.org/wiki/Q1293405","display_name":"Lumbar","level":2,"score":0.3644999861717224},{"id":"https://openalex.org/C2779480328","wikidata":"https://www.wikidata.org/wiki/Q1183684","display_name":"Decompression","level":2,"score":0.3181999921798706},{"id":"https://openalex.org/C2780221984","wikidata":"https://www.wikidata.org/wiki/Q131191","display_name":"Body mass index","level":2,"score":0.3172000050544739},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.30720001459121704},{"id":"https://openalex.org/C2779835254","wikidata":"https://www.wikidata.org/wiki/Q405478","display_name":"Lumbar vertebrae","level":3,"score":0.3068000078201294},{"id":"https://openalex.org/C2911149213","wikidata":"https://www.wikidata.org/wiki/Q1478321","display_name":"Spinal canal stenosis","level":4,"score":0.2989000082015991},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.2962999939918518},{"id":"https://openalex.org/C2780007028","wikidata":"https://www.wikidata.org/wiki/Q2343082","display_name":"Stenosis","level":2,"score":0.2831999957561493},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.2809999883174896},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.27709999680519104},{"id":"https://openalex.org/C2781310810","wikidata":"https://www.wikidata.org/wiki/Q1097931","display_name":"Neurogenic claudication","level":4,"score":0.27079999446868896},{"id":"https://openalex.org/C68312169","wikidata":"https://www.wikidata.org/wiki/Q216685","display_name":"Orthopedic surgery","level":2,"score":0.267300009727478},{"id":"https://openalex.org/C2781298600","wikidata":"https://www.wikidata.org/wiki/Q708143","display_name":"Arthrodesis","level":3,"score":0.26429998874664307},{"id":"https://openalex.org/C2776501849","wikidata":"https://www.wikidata.org/wiki/Q5781808","display_name":"Back pain","level":3,"score":0.25769999623298645}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.21182/jmisst.2026.03853","doi":"https://doi.org/10.21182/jmisst.2026.03853","is_oa":true,"landing_page_url":"https://doi.org/10.21182/jmisst.2026.03853","pdf_url":"https://www.jmisst.org/upload/pdf/jmisst-2026-03853.pdf","source":{"id":"https://openalex.org/S4210227605","display_name":"Journal of Minimally Invasive Spine Surgery and Technique","issn_l":"2508-2043","issn":["2508-2043"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Minimally Invasive Spine Surgery and Technique","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.21182/jmisst.2026.03853","doi":"https://doi.org/10.21182/jmisst.2026.03853","is_oa":true,"landing_page_url":"https://doi.org/10.21182/jmisst.2026.03853","pdf_url":"https://www.jmisst.org/upload/pdf/jmisst-2026-03853.pdf","source":{"id":"https://openalex.org/S4210227605","display_name":"Journal of Minimally Invasive Spine Surgery and Technique","issn_l":"2508-2043","issn":["2508-2043"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Minimally Invasive Spine Surgery and Technique","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7224910297.pdf","grobid_xml":"https://content.openalex.org/works/W7224910297.grobid-xml"},"referenced_works_count":28,"referenced_works":["https://openalex.org/W2019040750","https://openalex.org/W2068695634","https://openalex.org/W2117594670","https://openalex.org/W2124900413","https://openalex.org/W2142477073","https://openalex.org/W2340091217","https://openalex.org/W2428109599","https://openalex.org/W2557231616","https://openalex.org/W2578837154","https://openalex.org/W2622190875","https://openalex.org/W2777660356","https://openalex.org/W2779317722","https://openalex.org/W2791688867","https://openalex.org/W2791972955","https://openalex.org/W2800945375","https://openalex.org/W2801610967","https://openalex.org/W2806221742","https://openalex.org/W2888070864","https://openalex.org/W2893018007","https://openalex.org/W2901605768","https://openalex.org/W2906853630","https://openalex.org/W2954271619","https://openalex.org/W3028553436","https://openalex.org/W3087356388","https://openalex.org/W3113019924","https://openalex.org/W3133317423","https://openalex.org/W3162703641","https://openalex.org/W4220941946"],"related_works":["https://openalex.org/W4385690025","https://openalex.org/W3157669586","https://openalex.org/W2121233976","https://openalex.org/W2319779443","https://openalex.org/W4399697063","https://openalex.org/W7117702646","https://openalex.org/W2090753953","https://openalex.org/W4319063429","https://openalex.org/W2333288069","https://openalex.org/W2943226392"],"abstract_inverted_index":{"Objective:":[0],"This":[1],"study":[2],"aimed":[3],"to":[4,74,246],"compare":[5],"perioperative":[6],"parameters,":[7],"radiographic":[8,241],"fusion,":[9],"and":[10,27,51,93,115,122,228,242,252],"patient-reported":[11],"outcomes":[12,98,244],"(PROs)":[13],"between":[14,206],"transforaminal":[15],"lumbar":[16],"interbody":[17,100],"fusion":[18,101,202,217],"(TLIF)":[19],"performed":[20,29],"with":[21,30,38,53,62,67,71,103,135,192,255,271,282],"cement-augmented":[22],"fenestrated":[23],"pedicle":[24,33,250],"screws":[25,34,251],"(CAFPSs)":[26],"TLIF":[28,46],"conventional":[31,249,283],"noncemented":[32],"(NCPSs)":[35],"in":[36,148,153,169,174,190,220,224,232,269],"patients":[37,43,60,69,127,222,230,270],"osteopenia":[39],"or":[40],"osteoporosis.Methods:":[41],"Eighty":[42],"who":[44],"underwent":[45],"for":[47,113],"degenerative":[48],"spinal":[49],"stenosis":[50],"instability":[52],"radicular":[54],"symptoms":[55],"were":[56,64,204,253],"reviewed":[57],"retrospectively.":[58],"Forty":[59],"treated":[61,70],"CAFPS":[63,150,171,226],"matched":[65],"1:1":[66],"40":[68],"NCPS":[72,155,176,234],"according":[73],"age,":[75],"sex,":[76],"body":[77],"mass":[78],"index,":[79],"number":[80],"of":[81,133,140,248],"fused":[82],"levels.":[83],"Perioperative":[84],"parameters":[85],"included":[86,99,108],"operative":[87],"time,":[88],"blood":[89],"loss,":[90],"transfusion":[91],"rate,":[92],"postoperative":[94,188,258],"morphine":[95,164],"consumption.":[96],"Radiographic":[97],"assessed":[102],"the":[104,118,149,154,170,175,211,225,233],"Bridwell":[105,214],"classification.":[106],"PROs":[107],"visual":[109],"analog":[110],"scale":[111],"scores":[112],"back":[114],"leg":[116],"pain,":[117],"Oswestry":[119],"Disability":[120],"Index,":[121],"neurogenic":[123],"symptom":[124],"score.":[125],"All":[126],"had":[128],"at":[129,197],"least":[130],"24":[131],"months":[132],"follow-up,":[134,213],"a":[136],"mean":[137],"follow-up":[138],"duration":[139],"28.6\u00b16.3":[141],"months.Results:":[142],"Operative":[143],"time":[144,199],"was":[145,166,218],"significantly":[146,167],"longer":[147],"group":[151,156,172,177,227,235],"than":[152,173],"(334\u00b1106":[157],"minutes":[158],"vs.":[159,180],"254.0\u00b198.1":[160],"minutes,":[161],"p<0.001).":[162],"Postoperative":[163],"consumption":[165],"lower":[168,256],"(7.13\u00b113.6":[178],"mg":[179],"19.1\u00b121.3":[181],"mg,":[182],"p<0.01).":[183],"Both":[184],"groups":[185,207],"showed":[186],"significant":[187,194],"improvement":[189],"PROs,":[191],"no":[193],"between-group":[195],"differences":[196],"any":[198],"point.":[200],"Interbody":[201],"rates":[203],"comparable":[205,245],"throughout":[208],"follow-up.":[209],"At":[210],"2-year":[212],"grade":[215],"I":[216],"achieved":[219,281],"38":[221],"(95.0%)":[223],"36":[229],"(90.0%)":[231],"(p=0.396).Conclusions:":[236],"In":[237],"TLIF,":[238],"CAFPSs":[239],"provided":[240],"functional":[243],"those":[247],"associated":[254],"early":[257],"opioid":[259],"requirements.":[260],"Cement":[261],"augmentation":[262],"may":[263],"be":[264,280],"an":[265],"effective":[266],"fixation":[267,278],"strategy":[268],"compromised":[272],"bone":[273],"quality,":[274],"particularly":[275],"when":[276],"satisfactory":[277],"cannot":[279],"techniques":[284],"alone.":[285]},"counts_by_year":[],"updated_date":"2026-11-01T11:40:01.658920","created_date":"2026-10-31T00:00:00"}