{"id":"https://openalex.org/W7224893948","doi":"https://doi.org/10.1038/s41598-026-70447-z","title":"Effects of hydrothermal aging on the wear behavior, mechanical properties, and microstructure of a multilayered zirconia","display_name":"Effects of hydrothermal aging on the wear behavior, mechanical properties, and microstructure of a multilayered zirconia","publication_year":2026,"publication_date":"2026-10-31","ids":{"openalex":"https://openalex.org/W7224893948","doi":"https://doi.org/10.1038/s41598-026-70447-z"},"language":"en","primary_location":{"id":"doi:10.1038/s41598-026-70447-z","doi":"https://doi.org/10.1038/s41598-026-70447-z","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-026-70447-z","pdf_url":"https://www.nature.com/articles/s41598-026-70447-z_reference.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41598-026-70447-z_reference.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5058499746","display_name":"Karina Barbosa Souza","orcid":"https://orcid.org/0000-0001-7117-8250","observed_orcids":["https://orcid.org/0000-0001-7117-8250"]},"institutions":[{"id":"https://openalex.org/I879563668","display_name":"Universidade Estadual Paulista (Unesp)","ror":"https://ror.org/00987cb86","country_code":"BR","type":"education","lineage":["https://openalex.org/I879563668"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Karina Barbosa Souza","raw_affiliation_strings":["Department of Dental Materials and Prosthodontics, Institute of Science and Technology, S\u00e3o Paulo State University (UNESP), Av. Eng. Francisco Jos\u00e9 Longo, 777, Jardim S\u00e3o Dimas, S\u00e3o Jos\u00e9 dos Campos, 12245-000, S\u00e3o Paulo, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dental Materials and Prosthodontics, Institute of Science and Technology, S\u00e3o Paulo State University (UNESP), Av. Eng. Francisco Jos\u00e9 Longo, 777, Jardim S\u00e3o Dimas, S\u00e3o Jos\u00e9 dos Campos, 12245-000, S\u00e3o Paulo, Brazil","institution_ids":["https://openalex.org/I879563668"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013067542","display_name":"Tiago Moreira Bastos Campos","orcid":"https://orcid.org/0000-0001-8486-2510","observed_orcids":["https://orcid.org/0000-0001-8486-2510"]},"institutions":[{"id":"https://openalex.org/I169248161","display_name":"Universidade Federal de Pelotas","ror":"https://ror.org/05msy9z54","country_code":"BR","type":"education","lineage":["https://openalex.org/I169248161"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Tiago Moreira Bastos Campos","raw_affiliation_strings":["Faculty of Dentistry, Federal University of Pelotas, Gon\u00e7alves Chaves Street, 457, Pelotas, 96015-560, Rio Grande do Sul, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Dentistry, Federal University of Pelotas, Gon\u00e7alves Chaves Street, 457, Pelotas, 96015-560, Rio Grande do Sul, Brazil","institution_ids":["https://openalex.org/I169248161"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032760257","display_name":"Amir Mohidin Demachkia","orcid":"https://orcid.org/0000-0002-6315-1127","observed_orcids":["https://orcid.org/0000-0002-6315-1127"]},"institutions":[{"id":"https://openalex.org/I879563668","display_name":"Universidade Estadual Paulista (Unesp)","ror":"https://ror.org/00987cb86","country_code":"BR","type":"education","lineage":["https://openalex.org/I879563668"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Amir Mohidin Demachkia","raw_affiliation_strings":["Department of Dental Materials and Prosthodontics, Institute of Science and Technology, S\u00e3o Paulo State University (UNESP), Av. Eng. Francisco Jos\u00e9 Longo, 777, Jardim S\u00e3o Dimas, S\u00e3o Jos\u00e9 dos Campos, 12245-000, S\u00e3o Paulo, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dental Materials and Prosthodontics, Institute of Science and Technology, S\u00e3o Paulo State University (UNESP), Av. Eng. Francisco Jos\u00e9 Longo, 777, Jardim S\u00e3o Dimas, S\u00e3o Jos\u00e9 dos Campos, 12245-000, S\u00e3o Paulo, Brazil","institution_ids":["https://openalex.org/I879563668"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085811208","display_name":"Beatriz Serralheiro da Cruz","orcid":"https://orcid.org/0000-0002-3026-7705","observed_orcids":["https://orcid.org/0000-0002-3026-7705"]},"institutions":[{"id":"https://openalex.org/I879563668","display_name":"Universidade Estadual Paulista (Unesp)","ror":"https://ror.org/00987cb86","country_code":"BR","type":"education","lineage":["https://openalex.org/I879563668"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Beatriz Serralheiro da Cruz","raw_affiliation_strings":["Department of Dental Materials and Prosthodontics, Institute of Science and Technology, S\u00e3o Paulo State University (UNESP), Av. Eng. Francisco Jos\u00e9 Longo, 777, Jardim S\u00e3o Dimas, S\u00e3o Jos\u00e9 dos Campos, 12245-000, S\u00e3o Paulo, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dental Materials and Prosthodontics, Institute of Science and Technology, S\u00e3o Paulo State University (UNESP), Av. Eng. Francisco Jos\u00e9 Longo, 777, Jardim S\u00e3o Dimas, S\u00e3o Jos\u00e9 dos Campos, 12245-000, S\u00e3o Paulo, Brazil","institution_ids":["https://openalex.org/I879563668"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064704602","display_name":"Nath\u00e1lia de Carvalho Ramos","orcid":"https://orcid.org/0000-0002-0977-5350","observed_orcids":["https://orcid.org/0000-0002-0977-5350"]},"institutions":[{"id":"https://openalex.org/I879563668","display_name":"Universidade Estadual Paulista (Unesp)","ror":"https://ror.org/00987cb86","country_code":"BR","type":"education","lineage":["https://openalex.org/I879563668"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Nath\u00e1lia de Carvalho Ramos","raw_affiliation_strings":["Department of Dental Materials and Prosthodontics, Institute of Science and Technology, S\u00e3o Paulo State University (UNESP), Av. Eng. Francisco Jos\u00e9 Longo, 777, Jardim S\u00e3o Dimas, S\u00e3o Jos\u00e9 dos Campos, 12245-000, S\u00e3o Paulo, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dental Materials and Prosthodontics, Institute of Science and Technology, S\u00e3o Paulo State University (UNESP), Av. Eng. Francisco Jos\u00e9 Longo, 777, Jardim S\u00e3o Dimas, S\u00e3o Jos\u00e9 dos Campos, 12245-000, S\u00e3o Paulo, Brazil","institution_ids":["https://openalex.org/I879563668"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060428360","display_name":"Gilmar Patroc\u00ednio Thim","orcid":"https://orcid.org/0000-0001-6410-3031","observed_orcids":["https://orcid.org/0000-0001-6410-3031"]},"institutions":[{"id":"https://openalex.org/I107428990","display_name":"Instituto Tecnol\u00f3gico de Aeron\u00e1utica","ror":"https://ror.org/05vh67662","country_code":"BR","type":"education","lineage":["https://openalex.org/I107428990"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Gilmar Patroc\u00ednio Thim","raw_affiliation_strings":["Aeronautics Technological Institute (ITA), Pra\u00e7a Marechal Eduardo Gomes, 50, Vila das Acacias, S\u00e3o Jos\u00e9 dos Campos, 12228-900, S\u00e3o Paulo, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Aeronautics Technological Institute (ITA), Pra\u00e7a Marechal Eduardo Gomes, 50, Vila das Acacias, S\u00e3o Jos\u00e9 dos Campos, 12228-900, S\u00e3o Paulo, Brazil","institution_ids":["https://openalex.org/I107428990"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036958305","display_name":"Renata Marques de Melo","orcid":"https://orcid.org/0000-0003-0752-6294","observed_orcids":["https://orcid.org/0000-0003-0752-6294"]},"institutions":[{"id":"https://openalex.org/I879563668","display_name":"Universidade Estadual Paulista (Unesp)","ror":"https://ror.org/00987cb86","country_code":"BR","type":"education","lineage":["https://openalex.org/I879563668"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Renata Marques de Melo","raw_affiliation_strings":["Department of Dental Materials and Prosthodontics, Institute of Science and Technology, S\u00e3o Paulo State University (UNESP), Av. Eng. Francisco Jos\u00e9 Longo, 777, Jardim S\u00e3o Dimas, S\u00e3o Jos\u00e9 dos Campos, 12245-000, S\u00e3o Paulo, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dental Materials and Prosthodontics, Institute of Science and Technology, S\u00e3o Paulo State University (UNESP), Av. Eng. Francisco Jos\u00e9 Longo, 777, Jardim S\u00e3o Dimas, S\u00e3o Jos\u00e9 dos Campos, 12245-000, S\u00e3o Paulo, Brazil","institution_ids":["https://openalex.org/I879563668"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5028278688","display_name":"Marco Ant\u00f4n\u0131o Bott\u0131no","orcid":"https://orcid.org/0000-0003-0077-3161","observed_orcids":["https://orcid.org/0000-0003-0077-3161","https://orcid.org/0000-0001-8740-2464","https://orcid.org/0000-0003-2554-0700"]},"institutions":[{"id":"https://openalex.org/I879563668","display_name":"Universidade Estadual Paulista (Unesp)","ror":"https://ror.org/00987cb86","country_code":"BR","type":"education","lineage":["https://openalex.org/I879563668"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Marco Antonio Bottino","raw_affiliation_strings":["Department of Dental Materials and Prosthodontics, Institute of Science and Technology, S\u00e3o Paulo State University (UNESP), Av. Eng. Francisco Jos\u00e9 Longo, 777, Jardim S\u00e3o Dimas, S\u00e3o Jos\u00e9 dos Campos, 12245-000, S\u00e3o Paulo, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dental Materials and Prosthodontics, Institute of Science and Technology, S\u00e3o Paulo State University (UNESP), Av. Eng. Francisco Jos\u00e9 Longo, 777, Jardim S\u00e3o Dimas, S\u00e3o Jos\u00e9 dos Campos, 12245-000, S\u00e3o Paulo, Brazil","institution_ids":["https://openalex.org/I879563668"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5058499746"],"corresponding_institution_ids":["https://openalex.org/I879563668"],"apc_list":{"value":2690,"currency":"USD","value_usd":2690},"apc_paid":{"value":2690,"currency":"USD","value_usd":2690},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.72641093,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10132","display_name":"Advanced ceramic materials synthesis","score":0.35249999165534973,"subfield":{"id":"https://openalex.org/subfields/2503","display_name":"Ceramics and Composites"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10132","display_name":"Advanced ceramic materials synthesis","score":0.35249999165534973,"subfield":{"id":"https://openalex.org/subfields/2503","display_name":"Ceramics and Composites"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13470","display_name":"Surface Treatment and Coatings","score":0.16670000553131104,"subfield":{"id":"https://openalex.org/subfields/2210","display_name":"Mechanical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10377","display_name":"Metal and Thin Film Mechanics","score":0.12770000100135803,"subfield":{"id":"https://openalex.org/subfields/2211","display_name":"Mechanics of Materials"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hydrothermal-aging","display_name":"hydrothermal aging","score":0.9509999752044678},{"id":"https://openalex.org/keywords/zirconia","display_name":"zirconia","score":0.8379999995231628},{"id":"https://openalex.org/keywords/multilayered-ceramics","display_name":"multilayered ceramics","score":0.8090000152587891},{"id":"https://openalex.org/keywords/wear-behavior","display_name":"wear behavior","score":0.9419999718666077},{"id":"https://openalex.org/keywords/mechanical-properties","display_name":"mechanical properties","score":0.9990000128746033},{"id":"https://openalex.org/keywords/microstructure","display_name":"microstructure","score":0.9259999990463257},{"id":"https://openalex.org/keywords/thermal-barrier-coatings","display_name":"thermal barrier coatings","score":0.3880000114440918}],"concepts":[{"id":"https://openalex.org/C87976508","wikidata":"https://www.wikidata.org/wiki/Q1498213","display_name":"Microstructure","level":2,"score":0.8432000279426575},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.6855000257492065},{"id":"https://openalex.org/C156622251","wikidata":"https://www.wikidata.org/wiki/Q1036221","display_name":"Hydrothermal circulation","level":2,"score":0.6840000152587891},{"id":"https://openalex.org/C123609680","wikidata":"https://www.wikidata.org/wiki/Q225666","display_name":"Cubic zirconia","level":3,"score":0.5939000248908997},{"id":"https://openalex.org/C191897082","wikidata":"https://www.wikidata.org/wiki/Q11467","display_name":"Metallurgy","level":1,"score":0.43720000982284546},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.38929998874664307},{"id":"https://openalex.org/C500499127","wikidata":"https://www.wikidata.org/wiki/Q332154","display_name":"Ageing","level":2,"score":0.2224999964237213},{"id":"https://openalex.org/C6648577","wikidata":"https://www.wikidata.org/wiki/Q622669","display_name":"Porosity","level":2,"score":0.218299999833107},{"id":"https://openalex.org/C50515024","wikidata":"https://www.wikidata.org/wiki/Q826582","display_name":"X-ray crystallography","level":3,"score":0.20720000565052032},{"id":"https://openalex.org/C2983445633","wikidata":"https://www.wikidata.org/wiki/Q617224","display_name":"Wear resistance","level":2,"score":0.19689999520778656}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1038/s41598-026-70447-z","doi":"https://doi.org/10.1038/s41598-026-70447-z","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-026-70447-z","pdf_url":"https://www.nature.com/articles/s41598-026-70447-z_reference.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1038/s41598-026-70447-z","doi":"https://doi.org/10.1038/s41598-026-70447-z","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-026-70447-z","pdf_url":"https://www.nature.com/articles/s41598-026-70447-z_reference.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.4043000042438507}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320997","display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","ror":"https://ror.org/02ddkpn78"},{"id":"https://openalex.org/F4320321091","display_name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","ror":"https://ror.org/00x0ma614"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7224893948.pdf","grobid_xml":"https://content.openalex.org/works/W7224893948.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4409267027","https://openalex.org/W3135358285","https://openalex.org/W6981389991","https://openalex.org/W2335178894","https://openalex.org/W4415814291","https://openalex.org/W289072011","https://openalex.org/W1812789582","https://openalex.org/W2776614070","https://openalex.org/W4362456235","https://openalex.org/W4317438334"],"abstract_inverted_index":{"This":[0],"study":[1],"investigated":[2],"the":[3,9,103,119,123,134,138,147,157,165,180,186,202,213,217],"effects":[4],"of":[5,18,105,122,216,220],"hydrothermal":[6,174,192,224],"aging":[7,116,175,225],"on":[8,102],"wear,":[10],"surface":[11,67,135],"roughness,":[12,68],"mechanical":[13,182],"properties,":[14,183],"and":[15,42,45,74,92,96,110,150,160,168],"crystalline":[16],"composition":[17],"multilayered":[19,30,124,221],"zirconia.":[20],"Blocks":[21],"(14":[22],"\u00d7":[23,25,128,130],"14":[24],"1.5":[26],"mm)":[27],"fabricated":[28],"from":[29],"zirconia":[31,125,222],"(IPS":[32],"e.max":[33],"ZirCAD":[34],"Prime,":[35],"Ivoclar":[36],"Vivadent)":[37],"were":[38,63,79,99,112],"divided":[39],"into":[40],"non-aged":[41],"aged":[43],"groups":[44],"subjected":[46],"to":[47,126,191,208,223],"cyclic":[48],"loading":[49],"(150":[50],"N,":[51],"4":[52],"Hz,":[53],"600,000":[54],"cycles)":[55],"with":[56],"a":[57],"horizontal":[58],"sliding.":[59],"The":[60],"following":[61],"analyses":[62],"performed:":[64],"wear":[65,120,210],"volume,":[66],"XRD,":[69,108],"EDS,":[70,109],"SEM,":[71],"Vickers":[72],"hardness,":[73],"fracture":[75,97,161],"toughness.":[76],"Wear":[77],"measurements":[78],"analyzed":[80,87],"using":[81,88],"Student\u2019s":[82],"t-test.":[83],"Surface":[84],"roughness":[85,136],"was":[86,154],"ANOVA":[89],"On":[90],"ranks":[91],"Dunn\u2019s":[93],"test.":[94],"Hardness":[95,153],"toughness":[98,162],"evaluated":[100,181],"based":[101],"overlap":[104],"confidence":[106],"intervals.":[107],"SEM":[111],"qualitatively":[113],"analyzed.":[114],"Hydrothermal":[115],"significantly":[117],"increased":[118,155,163],"volume":[121],"27.8":[127],"10\u2075\u00b110.3":[129],"10\u2075\u00b5m\u00b3,":[131],"but":[132],"decreased":[133],"in":[137,146,156,164],"worn":[139],"area.":[140],"Aging":[141],"induced":[142],"phase":[143,204],"transformation":[144,205],"only":[145],"3Y-TZP":[148,158,169],"layer":[149,170],"transition":[151,166],"zone.":[152],"region,":[159],"zone":[167],"after":[171],"aging.":[172],"Overall,":[173],"did":[176],"not":[177],"adversely":[178],"affect":[179],"indicating":[184],"that":[185],"material":[187],"has":[188],"low":[189],"susceptibility":[190],"degradation,":[193],"which":[194],"may":[195,206],"be":[196,227],"favorable":[197],"for":[198],"clinical":[199,230],"application.":[200],"However,":[201],"observed":[203],"contribute":[207],"reduced":[209],"resistance.":[211],"Additionally,":[212],"distinct":[214],"responses":[215],"individual":[218],"layers":[219],"should":[226],"considered":[228],"during":[229],"decision-making.":[231]},"counts_by_year":[],"updated_date":"2026-11-02T09:45:03.842371","created_date":"2026-10-31T00:00:00"}