{"id":"https://openalex.org/W7224836733","doi":"https://doi.org/10.3390/antiox15111406","title":"A Review of the Analgesic Potential and Mechanisms of Ginsenoside Rb1 in the Treatment of Neuropathic Pain","display_name":"A Review of the Analgesic Potential and Mechanisms of Ginsenoside Rb1 in the Treatment of Neuropathic Pain","publication_year":2026,"publication_date":"2026-10-30","ids":{"openalex":"https://openalex.org/W7224836733","doi":"https://doi.org/10.3390/antiox15111406"},"language":"en","primary_location":{"id":"doi:10.3390/antiox15111406","doi":"https://doi.org/10.3390/antiox15111406","is_oa":true,"landing_page_url":"https://doi.org/10.3390/antiox15111406","pdf_url":null,"source":{"id":"https://openalex.org/S2737566431","display_name":"Antioxidants","issn_l":"2076-3921","issn":["2076-3921"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antioxidants","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.3390/antiox15111406","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5160211064","display_name":"Siyi Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4385474403","display_name":"Changchun University of Technology","ror":"https://ror.org/052pakb34","country_code":"CN","type":"education","lineage":["https://openalex.org/I4385474403"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Siyi Li","raw_affiliation_strings":["School of Chemical Engineering, Changchun University of Technology, Changchun 130051, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemical Engineering, Changchun University of Technology, Changchun 130051, China","institution_ids":["https://openalex.org/I4385474403"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089376849","display_name":"Fuqiang Shi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4385474403","display_name":"Changchun University of Technology","ror":"https://ror.org/052pakb34","country_code":"CN","type":"education","lineage":["https://openalex.org/I4385474403"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Fuqiang Shi","raw_affiliation_strings":["School of Chemical Engineering, Changchun University of Technology, Changchun 130051, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemical Engineering, Changchun University of Technology, Changchun 130051, China","institution_ids":["https://openalex.org/I4385474403"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010026045","display_name":"Xiangsheng Guan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4385474403","display_name":"Changchun University of Technology","ror":"https://ror.org/052pakb34","country_code":"CN","type":"education","lineage":["https://openalex.org/I4385474403"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiangsheng Guan","raw_affiliation_strings":["School of Chemical Engineering, Changchun University of Technology, Changchun 130051, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemical Engineering, Changchun University of Technology, Changchun 130051, China","institution_ids":["https://openalex.org/I4385474403"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5139085077","display_name":"Shuai Chen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4385474403","display_name":"Changchun University of Technology","ror":"https://ror.org/052pakb34","country_code":"CN","type":"education","lineage":["https://openalex.org/I4385474403"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shuai Chen","raw_affiliation_strings":["School of Chemical Engineering, Changchun University of Technology, Changchun 130051, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemical Engineering, Changchun University of Technology, Changchun 130051, China","institution_ids":["https://openalex.org/I4385474403"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160173072","display_name":"Xuyan He","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4385474403","display_name":"Changchun University of Technology","ror":"https://ror.org/052pakb34","country_code":"CN","type":"education","lineage":["https://openalex.org/I4385474403"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xuyan He","raw_affiliation_strings":["School of Chemical Engineering, Changchun University of Technology, Changchun 130051, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemical Engineering, Changchun University of Technology, Changchun 130051, China","institution_ids":["https://openalex.org/I4385474403"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114181503","display_name":"ZiWen Zhang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4385474403","display_name":"Changchun University of Technology","ror":"https://ror.org/052pakb34","country_code":"CN","type":"education","lineage":["https://openalex.org/I4385474403"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ziwen Zhang","raw_affiliation_strings":["School of Chemical Engineering, Changchun University of Technology, Changchun 130051, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemical Engineering, Changchun University of Technology, Changchun 130051, China","institution_ids":["https://openalex.org/I4385474403"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160151636","display_name":"Ruyi Zi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4385474403","display_name":"Changchun University of Technology","ror":"https://ror.org/052pakb34","country_code":"CN","type":"education","lineage":["https://openalex.org/I4385474403"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ruyi Zi","raw_affiliation_strings":["School of Chemical Engineering, Changchun University of Technology, Changchun 130051, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemical Engineering, Changchun University of Technology, Changchun 130051, China","institution_ids":["https://openalex.org/I4385474403"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160228932","display_name":"Jiayi Guo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4385474403","display_name":"Changchun University of Technology","ror":"https://ror.org/052pakb34","country_code":"CN","type":"education","lineage":["https://openalex.org/I4385474403"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiayi Guo","raw_affiliation_strings":["School of Chemical Engineering, Changchun University of Technology, Changchun 130051, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemical Engineering, Changchun University of Technology, Changchun 130051, China","institution_ids":["https://openalex.org/I4385474403"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050675940","display_name":"Esi Domi","orcid":"https://orcid.org/0000-0001-5726-4814","observed_orcids":["https://orcid.org/0000-0001-5726-4814"]},"institutions":[{"id":"https://openalex.org/I112859197","display_name":"Universit\u00e0 di Camerino","ror":"https://ror.org/0005w8d69","country_code":"IT","type":"education","lineage":["https://openalex.org/I112859197"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Esi Domi","raw_affiliation_strings":["Pharmacology Unit, School of Pharmacy, University of Camerino, Via Madonna delle Carceri 9, 62032 Camerino, Italy"],"raw_orcid":"https://orcid.org/0000-0001-5726-4814","affiliations":[{"raw_affiliation_string":"Pharmacology Unit, School of Pharmacy, University of Camerino, Via Madonna delle Carceri 9, 62032 Camerino, Italy","institution_ids":["https://openalex.org/I112859197"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060816841","display_name":"Massimo Ubaldi","orcid":"https://orcid.org/0000-0002-4089-2483","observed_orcids":["https://orcid.org/0000-0002-4089-2483"]},"institutions":[{"id":"https://openalex.org/I112859197","display_name":"Universit\u00e0 di Camerino","ror":"https://ror.org/0005w8d69","country_code":"IT","type":"education","lineage":["https://openalex.org/I112859197"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Massimo Ubaldi","raw_affiliation_strings":["Pharmacology Unit, School of Pharmacy, University of Camerino, Via Madonna delle Carceri 9, 62032 Camerino, Italy"],"raw_orcid":"https://orcid.org/0000-0002-4089-2483","affiliations":[{"raw_affiliation_string":"Pharmacology Unit, School of Pharmacy, University of Camerino, Via Madonna delle Carceri 9, 62032 Camerino, Italy","institution_ids":["https://openalex.org/I112859197"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066708131","display_name":"Roberto Ciccocioppo","orcid":"https://orcid.org/0000-0003-3126-9240","observed_orcids":["https://orcid.org/0000-0003-3126-9240"]},"institutions":[{"id":"https://openalex.org/I112859197","display_name":"Universit\u00e0 di Camerino","ror":"https://ror.org/0005w8d69","country_code":"IT","type":"education","lineage":["https://openalex.org/I112859197"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Roberto Ciccocioppo","raw_affiliation_strings":["Pharmacology Unit, School of Pharmacy, University of Camerino, Via Madonna delle Carceri 9, 62032 Camerino, Italy"],"raw_orcid":"https://orcid.org/0000-0003-3126-9240","affiliations":[{"raw_affiliation_string":"Pharmacology Unit, School of Pharmacy, University of Camerino, Via Madonna delle Carceri 9, 62032 Camerino, Italy","institution_ids":["https://openalex.org/I112859197"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5160183258","display_name":"Hongwu Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4385474403","display_name":"Changchun University of Technology","ror":"https://ror.org/052pakb34","country_code":"CN","type":"education","lineage":["https://openalex.org/I4385474403"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Hongwu Li","raw_affiliation_strings":["School of Chemical Engineering, Changchun University of Technology, Changchun 130051, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemical Engineering, Changchun University of Technology, Changchun 130051, China","institution_ids":["https://openalex.org/I4385474403"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5160183258"],"corresponding_institution_ids":["https://openalex.org/I4385474403"],"apc_list":{"value":2900,"currency":"CHF","value_usd":3499},"apc_paid":{"value":2900,"currency":"CHF","value_usd":3499},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.74574538,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"15","issue":"11","first_page":"1406","last_page":"1406"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11889","display_name":"Ginseng Biological Effects and Applications","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11889","display_name":"Ginseng Biological Effects and Applications","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10196","display_name":"Pain Mechanisms and Treatments","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13677","display_name":"Magnolia and Illicium research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2742","display_name":"Rehabilitation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ginsenoside-rb1","display_name":"ginsenoside Rb1","score":0.9980000257492065},{"id":"https://openalex.org/keywords/neuropathic-pain","display_name":"neuropathic pain","score":0.9610000252723694},{"id":"https://openalex.org/keywords/pain-relief","display_name":"analgesia","score":0.8679999709129333},{"id":"https://openalex.org/keywords/ginseng","display_name":"ginseng","score":0.8209999799728394},{"id":"https://openalex.org/keywords/triterpenoid-saponins","display_name":"triterpenoid saponins","score":0.8790000081062317},{"id":"https://openalex.org/keywords/signaling-pathways","display_name":"signaling pathways","score":0.7279999852180481},{"id":"https://openalex.org/keywords/neuroprotection","display_name":"neuroprotection","score":0.8629999756813049},{"id":"https://openalex.org/keywords/anti-inflammatory-activity","display_name":"anti-inflammatory activity","score":0.8709999918937683},{"id":"https://openalex.org/keywords/antioxidant-activity","display_name":"antioxidant activity","score":0.9079999923706055},{"id":"https://openalex.org/keywords/traditional-chinese-medicine","display_name":"traditional Chinese medicine","score":0.6579999923706055}],"concepts":[{"id":"https://openalex.org/C2777107010","wikidata":"https://www.wikidata.org/wiki/Q2798704","display_name":"Neuropathic pain","level":2,"score":0.7329000234603882},{"id":"https://openalex.org/C2780820201","wikidata":"https://www.wikidata.org/wiki/Q173235","display_name":"Analgesic","level":2,"score":0.7315000295639038},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.690500020980835},{"id":"https://openalex.org/C2779232237","wikidata":"https://www.wikidata.org/wiki/Q20817212","display_name":"Ginseng","level":3,"score":0.5636000037193298},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.5370000004768372},{"id":"https://openalex.org/C25498285","wikidata":"https://www.wikidata.org/wiki/Q1981368","display_name":"Neuroprotection","level":2,"score":0.5174000263214111},{"id":"https://openalex.org/C2909432430","wikidata":"https://www.wikidata.org/wiki/Q173235","display_name":"Analgesic agents","level":3,"score":0.4657000005245209},{"id":"https://openalex.org/C2776539398","wikidata":"https://www.wikidata.org/wiki/Q59662497","display_name":"Ginsenoside","level":4,"score":0.4018999934196472},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.3986999988555908},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.38519999384880066},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.352400004863739},{"id":"https://openalex.org/C140608501","wikidata":"https://www.wikidata.org/wiki/Q7318358","display_name":"Review article","level":2,"score":0.30230000615119934},{"id":"https://openalex.org/C2781118164","wikidata":"https://www.wikidata.org/wiki/Q1088113","display_name":"Chronic pain","level":2,"score":0.3018999993801117},{"id":"https://openalex.org/C2776999253","wikidata":"https://www.wikidata.org/wiki/Q1304270","display_name":"Combination therapy","level":2,"score":0.2782000005245209}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.3390/antiox15111406","doi":"https://doi.org/10.3390/antiox15111406","is_oa":true,"landing_page_url":"https://doi.org/10.3390/antiox15111406","pdf_url":null,"source":{"id":"https://openalex.org/S2737566431","display_name":"Antioxidants","issn_l":"2076-3921","issn":["2076-3921"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antioxidants","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.3390/antiox15111406","doi":"https://doi.org/10.3390/antiox15111406","is_oa":true,"landing_page_url":"https://doi.org/10.3390/antiox15111406","pdf_url":null,"source":{"id":"https://openalex.org/S2737566431","display_name":"Antioxidants","issn_l":"2076-3921","issn":["2076-3921"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antioxidants","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9476000070571899}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":92,"referenced_works":["https://openalex.org/W1566088586","https://openalex.org/W1968651827","https://openalex.org/W2045758596","https://openalex.org/W2113154361","https://openalex.org/W2139249399","https://openalex.org/W2428054972","https://openalex.org/W2569648480","https://openalex.org/W2605531277","https://openalex.org/W2749719837","https://openalex.org/W3000887831","https://openalex.org/W3010119070","https://openalex.org/W3094563918","https://openalex.org/W3101199016","https://openalex.org/W3122524458","https://openalex.org/W3157632616","https://openalex.org/W3161647032","https://openalex.org/W3164849087","https://openalex.org/W3181827753","https://openalex.org/W3195357027","https://openalex.org/W3208219538","https://openalex.org/W3213630187","https://openalex.org/W4206610946","https://openalex.org/W4220694531","https://openalex.org/W4223906789","https://openalex.org/W4224324996","https://openalex.org/W4281293521","https://openalex.org/W4282928204","https://openalex.org/W4286560765","https://openalex.org/W4292937759","https://openalex.org/W4298004480","https://openalex.org/W4298005662","https://openalex.org/W4308519466","https://openalex.org/W4316664316","https://openalex.org/W4319773733","https://openalex.org/W4324121813","https://openalex.org/W4377030409","https://openalex.org/W4381546269","https://openalex.org/W4382051569","https://openalex.org/W4385251687","https://openalex.org/W4387521139","https://openalex.org/W4389725956","https://openalex.org/W4391315523","https://openalex.org/W4392378128","https://openalex.org/W4392655351","https://openalex.org/W4393373409","https://openalex.org/W4394894099","https://openalex.org/W4395467994","https://openalex.org/W4399430386","https://openalex.org/W4399973704","https://openalex.org/W4400615497","https://openalex.org/W4400849553","https://openalex.org/W4400869063","https://openalex.org/W4401612949","https://openalex.org/W4401931358","https://openalex.org/W4403294050","https://openalex.org/W4403321375","https://openalex.org/W4404739025","https://openalex.org/W4404895321","https://openalex.org/W4405199547","https://openalex.org/W4405950188","https://openalex.org/W4406057914","https://openalex.org/W4406063402","https://openalex.org/W4406401688","https://openalex.org/W4407174596","https://openalex.org/W4407753317","https://openalex.org/W4409161097","https://openalex.org/W4409296588","https://openalex.org/W4411011404","https://openalex.org/W4411106656","https://openalex.org/W4411956410","https://openalex.org/W4411967425","https://openalex.org/W4412623166","https://openalex.org/W4412746155","https://openalex.org/W4412828515","https://openalex.org/W4414516914","https://openalex.org/W4415121478","https://openalex.org/W4415826763","https://openalex.org/W4417092202","https://openalex.org/W4417178359","https://openalex.org/W7118693289","https://openalex.org/W7118815109","https://openalex.org/W7124285257","https://openalex.org/W7125817295","https://openalex.org/W7129263923","https://openalex.org/W7134116833","https://openalex.org/W7140140638","https://openalex.org/W7148521786","https://openalex.org/W7159943337","https://openalex.org/W7163389857","https://openalex.org/W7166562543","https://openalex.org/W7172256750","https://openalex.org/W7205009734"],"related_works":["https://openalex.org/W4391170738","https://openalex.org/W4308519466","https://openalex.org/W3188869677","https://openalex.org/W3101199016","https://openalex.org/W4213150829","https://openalex.org/W4210853208","https://openalex.org/W4281746897","https://openalex.org/W2920918580","https://openalex.org/W2357568461","https://openalex.org/W2390693792"],"abstract_inverted_index":{"The":[0],"use":[1,186],"of":[2,11,39,44,88,162,169,205,210],"ginseng":[3],"has":[4,77,121],"long":[5],"been":[6,78],"documented":[7],"in":[8,62,85,159,187,207],"classical":[9],"texts":[10],"traditional":[12],"Chinese":[13],"medicine,":[14],"where":[15],"it":[16],"is":[17,53,59],"commonly":[18],"used":[19],"to":[20,80,108,115],"treat":[21,145],"conditions":[22],"involving":[23],"physical":[24],"weakness":[25],"and":[26,73,76,95,113,155],"depletion,":[27],"as":[28,30,34,51,96,123,176,181],"well":[29],"pain-related":[31],"disorders.":[32],"Ginsenosides,":[33],"the":[35,42,86,138,160,170,203,208],"primary":[36],"active":[37],"components":[38],"ginseng,":[40],"are":[41],"focus":[43],"modern":[45],"pharmacological":[46,67,111],"research.":[47],"Ginsenoside":[48],"Rb1":[49],"(abbreviated":[50],"G-Rb1)":[52],"a":[54,124,166,177,182,196],"tetracyclic":[55],"triterpenoid":[56],"compound":[57,127],"that":[58],"abundantly":[60],"distributed":[61],"ginseng.":[63],"It":[64],"exhibits":[65],"multiple":[66,117],"activities,":[68],"including":[69],"antioxidant,":[70],"analgesic,":[71],"anti-inflammatory,":[72],"neuroprotective":[74],"effects,":[75],"proven":[79],"exert":[81],"notable":[82],"therapeutic":[83,99],"efficacy":[84],"treatment":[87,161,209],"neurological":[89],"disorders,":[90,94],"cardiovascular":[91],"diseases,":[92,147],"metabolic":[93],"an":[97],"anti-cancer":[98],"agent.":[100],"Neuropathic":[101],"pain":[102],"(NP)":[103],"involves":[104],"complex":[105],"mechanisms.":[106],"Owing":[107],"its":[109,149,157],"diverse":[110],"properties":[112],"potential":[114],"modulate":[116],"signaling":[118,153],"pathways,":[119,154],"G-Rb1":[120,143,173,206],"emerged":[122],"promising":[125],"natural":[126],"for":[128,132,185,198],"investigating":[129],"novel":[130,178],"strategies":[131],"NP":[133],"management.":[134],"This":[135,193],"review":[136],"analyzes":[137],"possible":[139],"mechanisms":[140],"by":[141],"which":[142],"may":[144],"various":[146],"explores":[148],"interactions":[150],"with":[151,189],"different":[152],"demonstrates":[156],"feasibility":[158],"NP.":[163,211],"Based":[164],"on":[165,202],"comprehensive":[167],"analysis":[168],"existing":[171],"literature,":[172],"shows":[174],"promise":[175],"analgesic":[179,191],"or":[180],"complementary":[183],"component":[184],"combination":[188],"other":[190],"drugs.":[192],"paper":[194],"provides":[195],"reference":[197],"further":[199],"in-depth":[200],"research":[201],"application":[204]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2026-10-31T00:00:00"}