{"id":"https://openalex.org/W7224756609","doi":"https://doi.org/10.3390/microorganisms14112475","title":"The Gut\u2013Thyroid Axis in Hashimoto\u2019s Disease: Evidence of Reduced Short Chain Fatty Acid Producers and Enhanced Virulence Pathways","display_name":"The Gut\u2013Thyroid Axis in Hashimoto\u2019s Disease: Evidence of Reduced Short Chain Fatty Acid Producers and Enhanced Virulence Pathways","publication_year":2026,"publication_date":"2026-10-30","ids":{"openalex":"https://openalex.org/W7224756609","doi":"https://doi.org/10.3390/microorganisms14112475"},"language":"en","primary_location":{"id":"doi:10.3390/microorganisms14112475","doi":"https://doi.org/10.3390/microorganisms14112475","is_oa":true,"landing_page_url":"https://doi.org/10.3390/microorganisms14112475","pdf_url":null,"source":{"id":"https://openalex.org/S4210222090","display_name":"Microorganisms","issn_l":"2076-2607","issn":["2076-2607"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microorganisms","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.3390/microorganisms14112475","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5160185837","display_name":"Miled Bouameur","orcid":"https://orcid.org/0009-0004-4132-1609","observed_orcids":["https://orcid.org/0009-0004-4132-1609"]},"institutions":[{"id":"https://openalex.org/I125485651","display_name":"University Fr\u00e8res Mentouri Constantine 1","ror":"https://ror.org/017wv6808","country_code":"DZ","type":"education","lineage":["https://openalex.org/I125485651"]}],"countries":["DZ"],"is_corresponding":false,"raw_author_name":"Miled Bouameur","raw_affiliation_strings":["Department of Molecular Biology, Cellular and Biochemistry, University of Constantine 1, Constantine 25000, Algeria","Laboratory of Food Sciences, Formulation, Innovation, Valorization & Artificial Intelligence (SAFIVIA), Institute of Nutrition, Food and Agri-Food, University of Constantine 1, Constantine 25000, Algeria"],"raw_orcid":"https://orcid.org/0009-0004-4132-1609","affiliations":[{"raw_affiliation_string":"Department of Molecular Biology, Cellular and Biochemistry, University of Constantine 1, Constantine 25000, Algeria","institution_ids":["https://openalex.org/I125485651"]},{"raw_affiliation_string":"Laboratory of Food Sciences, Formulation, Innovation, Valorization & Artificial Intelligence (SAFIVIA), Institute of Nutrition, Food and Agri-Food, University of Constantine 1, Constantine 25000, Algeria","institution_ids":["https://openalex.org/I125485651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020434633","display_name":"Doria Na\u00efla Bouchedja","orcid":"https://orcid.org/0000-0002-5623-4821","observed_orcids":["https://orcid.org/0000-0002-5623-4821"]},"institutions":[{"id":"https://openalex.org/I125485651","display_name":"University Fr\u00e8res Mentouri Constantine 1","ror":"https://ror.org/017wv6808","country_code":"DZ","type":"education","lineage":["https://openalex.org/I125485651"]}],"countries":["DZ"],"is_corresponding":true,"raw_author_name":"Naila Bouchedja","raw_affiliation_strings":["Laboratory of Food Sciences, Formulation, Innovation, Valorization & Artificial Intelligence (SAFIVIA), Institute of Nutrition, Food and Agri-Food, University of Constantine 1, Constantine 25000, Algeria"],"raw_orcid":"https://orcid.org/0000-0002-5623-4821","affiliations":[{"raw_affiliation_string":"Laboratory of Food Sciences, Formulation, Innovation, Valorization & Artificial Intelligence (SAFIVIA), Institute of Nutrition, Food and Agri-Food, University of Constantine 1, Constantine 25000, Algeria","institution_ids":["https://openalex.org/I125485651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037570885","display_name":"Nassim Madi","orcid":"https://orcid.org/0009-0008-3987-9047","observed_orcids":["https://orcid.org/0009-0008-3987-9047"]},"institutions":[{"id":"https://openalex.org/I187560010","display_name":"University of B\u00e9ja\u00efa","ror":"https://ror.org/03yb2hp88","country_code":"DZ","type":"education","lineage":["https://openalex.org/I187560010"]},{"id":"https://openalex.org/I4402554052","display_name":"Centre de Recherche en Technologies Agro-Alimentaires","ror":"https://ror.org/00yf0rv20","country_code":"DZ","type":"facility","lineage":["https://openalex.org/I4210146520","https://openalex.org/I4402554052"]}],"countries":["DZ"],"is_corresponding":false,"raw_author_name":"Nassim Madi","raw_affiliation_strings":["Agro-Food Technology Research Center, University of Bejaia, Bejaia 06000, Algeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Agro-Food Technology Research Center, University of Bejaia, Bejaia 06000, Algeria","institution_ids":["https://openalex.org/I187560010","https://openalex.org/I4402554052"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102077070","display_name":"Nassim Nouri","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4391767747","display_name":"University of Constantine 3","ror":"https://ror.org/04wk25q62","country_code":"DZ","type":"education","lineage":["https://openalex.org/I4391767747"]}],"countries":["DZ"],"is_corresponding":false,"raw_author_name":"Nassim Nouri","raw_affiliation_strings":["Department of Endocrinology and Diabetes, Medicine Faculty of Constantine, University Constantine 3, Constantine 25000, Algeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology and Diabetes, Medicine Faculty of Constantine, University Constantine 3, Constantine 25000, Algeria","institution_ids":["https://openalex.org/I4391767747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001284935","display_name":"Lamia Elmechta","orcid":"https://orcid.org/0000-0003-2585-0872","observed_orcids":["https://orcid.org/0000-0003-2585-0872"]},"institutions":[{"id":"https://openalex.org/I125485651","display_name":"University Fr\u00e8res Mentouri Constantine 1","ror":"https://ror.org/017wv6808","country_code":"DZ","type":"education","lineage":["https://openalex.org/I125485651"]}],"countries":["DZ"],"is_corresponding":false,"raw_author_name":"Lamia Elmechta","raw_affiliation_strings":["Laboratory of Food Sciences, Formulation, Innovation, Valorization & Artificial Intelligence (SAFIVIA), Institute of Nutrition, Food and Agri-Food, University of Constantine 1, Constantine 25000, Algeria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Food Sciences, Formulation, Innovation, Valorization & Artificial Intelligence (SAFIVIA), Institute of Nutrition, Food and Agri-Food, University of Constantine 1, Constantine 25000, Algeria","institution_ids":["https://openalex.org/I125485651"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5079877138","display_name":"Yacine Amar","orcid":"https://orcid.org/0000-0002-4134-0760","observed_orcids":["https://orcid.org/0000-0002-4134-0760"]},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Yacine Amar","raw_affiliation_strings":["School of Medicine, Technical University of Munich, 80802 Munich, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Medicine, Technical University of Munich, 80802 Munich, Germany","institution_ids":["https://openalex.org/I62916508"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5020434633","https://openalex.org/A5079877138"],"corresponding_institution_ids":["https://openalex.org/I125485651","https://openalex.org/I62916508"],"apc_list":{"value":2700,"currency":"CHF","value_usd":3258},"apc_paid":{"value":2700,"currency":"CHF","value_usd":3258},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.77056123,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"14","issue":"11","first_page":"2475","last_page":"2475"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hashimoto-s-thyroiditis","display_name":"Hashimoto's thyroiditis","score":0.9950000047683716},{"id":"https://openalex.org/keywords/gut-thyroid-axis","display_name":"gut-thyroid axis","score":0.8939999938011169},{"id":"https://openalex.org/keywords/gut-microbiota","display_name":"gut microbiota","score":0.8740000128746033},{"id":"https://openalex.org/keywords/gut-dysbiosis","display_name":"gut dysbiosis","score":0.9210000038146973},{"id":"https://openalex.org/keywords/short-chain-fatty-acids","display_name":"short-chain fatty acids","score":0.9100000262260437},{"id":"https://openalex.org/keywords/faecalibacterium","display_name":"Faecalibacterium","score":0.9959999918937683},{"id":"https://openalex.org/keywords/bacterial-virulence","display_name":"bacterial virulence","score":0.7379999756813049},{"id":"https://openalex.org/keywords/antimicrobial-resistance","display_name":"antimicrobial resistance","score":0.8690000176429749},{"id":"https://openalex.org/keywords/staphylococcus-aureus","display_name":"Staphylococcus aureus","score":0.9950000047683716},{"id":"https://openalex.org/keywords/staphylococcal-enterotoxins","display_name":"staphylococcal enterotoxins","score":0.8009999990463257},{"id":"https://openalex.org/keywords/beta-lactam-resistance","display_name":"beta-lactam resistance","score":0.9100000262260437},{"id":"https://openalex.org/keywords/autoimmune-thyroid-disease","display_name":"autoimmune thyroid disease","score":0.9139999747276306},{"id":"https://openalex.org/keywords/pro-inflammatory-pathways","display_name":"pro-inflammatory pathways","score":0.5490000247955322},{"id":"https://openalex.org/keywords/microbial-diversity","display_name":"microbial diversity","score":0.6299999952316284}],"concepts":[{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.683899998664856},{"id":"https://openalex.org/C60987743","wikidata":"https://www.wikidata.org/wiki/Q1460232","display_name":"Virulence","level":3,"score":0.6736999750137329},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6299999952316284},{"id":"https://openalex.org/C2777165150","wikidata":"https://www.wikidata.org/wiki/Q269334","display_name":"Dysbiosis","level":3,"score":0.6057000160217285},{"id":"https://openalex.org/C2780027724","wikidata":"https://www.wikidata.org/wiki/Q288892","display_name":"Ruminococcus","level":3,"score":0.5792999863624573},{"id":"https://openalex.org/C143121216","wikidata":"https://www.wikidata.org/wiki/Q1330402","display_name":"Microbiome","level":2,"score":0.5637999773025513},{"id":"https://openalex.org/C2777368272","wikidata":"https://www.wikidata.org/wiki/Q418073","display_name":"Ribotyping","level":4,"score":0.486299991607666},{"id":"https://openalex.org/C2779489039","wikidata":"https://www.wikidata.org/wiki/Q188121","display_name":"Staphylococcus aureus","level":3,"score":0.44110000133514404},{"id":"https://openalex.org/C2780423288","wikidata":"https://www.wikidata.org/wiki/Q7242440","display_name":"Prevotella","level":3,"score":0.41620001196861267},{"id":"https://openalex.org/C2779288629","wikidata":"https://www.wikidata.org/wiki/Q199695","display_name":"Staphylococcus","level":4,"score":0.39559999108314514},{"id":"https://openalex.org/C2777954195","wikidata":"https://www.wikidata.org/wiki/Q132209","display_name":"Neisseria","level":3,"score":0.3903999924659729},{"id":"https://openalex.org/C2777195454","wikidata":"https://www.wikidata.org/wiki/Q16399","display_name":"Euthyroid","level":3,"score":0.38769999146461487},{"id":"https://openalex.org/C543025807","wikidata":"https://www.wikidata.org/wiki/Q61476","display_name":"Fatty acid","level":2,"score":0.3785000145435333},{"id":"https://openalex.org/C91478284","wikidata":"https://www.wikidata.org/wiki/Q6623796","display_name":"Human microbiome","level":3,"score":0.3671000003814697},{"id":"https://openalex.org/C539455810","wikidata":"https://www.wikidata.org/wiki/Q739734","display_name":"Gut flora","level":2,"score":0.3619000017642975},{"id":"https://openalex.org/C2778883795","wikidata":"https://www.wikidata.org/wiki/Q804517","display_name":"Pathogenic bacteria","level":3,"score":0.3610999882221222},{"id":"https://openalex.org/C526584372","wikidata":"https://www.wikidata.org/wiki/Q16399","display_name":"Thyroid","level":2,"score":0.3328000009059906},{"id":"https://openalex.org/C4937899","wikidata":"https://www.wikidata.org/wiki/Q68541106","display_name":"Antimicrobial","level":2,"score":0.32330000400543213},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.30000001192092896},{"id":"https://openalex.org/C2776989901","wikidata":"https://www.wikidata.org/wiki/Q134668","display_name":"Gammaproteobacteria","level":4,"score":0.2973000109195709},{"id":"https://openalex.org/C118687296","wikidata":"https://www.wikidata.org/wiki/Q905754","display_name":"Quorum sensing","level":4,"score":0.2865999937057495},{"id":"https://openalex.org/C66999527","wikidata":"https://www.wikidata.org/wiki/Q421978","display_name":"Enterotoxin","level":4,"score":0.28220000863075256},{"id":"https://openalex.org/C2778696486","wikidata":"https://www.wikidata.org/wiki/Q11835644","display_name":"Thyroiditis","level":3,"score":0.2687999904155731},{"id":"https://openalex.org/C15151743","wikidata":"https://www.wikidata.org/wiki/Q903778","display_name":"Metagenomics","level":3,"score":0.2651999890804291},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.26489999890327454},{"id":"https://openalex.org/C2908570505","wikidata":"https://www.wikidata.org/wiki/Q422597","display_name":"Caproic Acid","level":2,"score":0.25589999556541443},{"id":"https://openalex.org/C2778726529","wikidata":"https://www.wikidata.org/wiki/Q3760144","display_name":"Staphylococcus haemolyticus","level":5,"score":0.2515000104904175}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.3390/microorganisms14112475","doi":"https://doi.org/10.3390/microorganisms14112475","is_oa":true,"landing_page_url":"https://doi.org/10.3390/microorganisms14112475","pdf_url":null,"source":{"id":"https://openalex.org/S4210222090","display_name":"Microorganisms","issn_l":"2076-2607","issn":["2076-2607"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microorganisms","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.3390/microorganisms14112475","doi":"https://doi.org/10.3390/microorganisms14112475","is_oa":true,"landing_page_url":"https://doi.org/10.3390/microorganisms14112475","pdf_url":null,"source":{"id":"https://openalex.org/S4210222090","display_name":"Microorganisms","issn_l":"2076-2607","issn":["2076-2607"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microorganisms","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":70,"referenced_works":["https://openalex.org/W173990113","https://openalex.org/W1980496604","https://openalex.org/W1988821718","https://openalex.org/W2011301426","https://openalex.org/W2044235282","https://openalex.org/W2050783903","https://openalex.org/W2067274593","https://openalex.org/W2068721358","https://openalex.org/W2083189217","https://openalex.org/W2130410032","https://openalex.org/W2131902769","https://openalex.org/W2148501322","https://openalex.org/W2152885278","https://openalex.org/W2165067288","https://openalex.org/W2222614299","https://openalex.org/W2522919408","https://openalex.org/W2578250538","https://openalex.org/W2613168999","https://openalex.org/W2752038086","https://openalex.org/W2783154851","https://openalex.org/W2891907278","https://openalex.org/W2955310899","https://openalex.org/W2971859269","https://openalex.org/W2991554478","https://openalex.org/W3030441098","https://openalex.org/W3033707601","https://openalex.org/W3034977328","https://openalex.org/W3096586635","https://openalex.org/W3099348830","https://openalex.org/W3109438439","https://openalex.org/W3128261063","https://openalex.org/W3130657850","https://openalex.org/W3135851279","https://openalex.org/W3136819994","https://openalex.org/W3156977781","https://openalex.org/W3165005733","https://openalex.org/W3213336521","https://openalex.org/W4210553530","https://openalex.org/W4211084027","https://openalex.org/W4221042154","https://openalex.org/W4224436908","https://openalex.org/W4292416428","https://openalex.org/W4304890757","https://openalex.org/W4307370758","https://openalex.org/W4307425304","https://openalex.org/W4308198114","https://openalex.org/W4312203412","https://openalex.org/W4313198947","https://openalex.org/W4315796652","https://openalex.org/W4376132442","https://openalex.org/W4384276655","https://openalex.org/W4384819225","https://openalex.org/W4385330162","https://openalex.org/W4387422396","https://openalex.org/W4387563049","https://openalex.org/W4391320385","https://openalex.org/W4392044405","https://openalex.org/W4392466489","https://openalex.org/W4392922337","https://openalex.org/W4398182689","https://openalex.org/W4399369129","https://openalex.org/W4399890335","https://openalex.org/W4401470321","https://openalex.org/W4402094667","https://openalex.org/W4402508053","https://openalex.org/W4404512120","https://openalex.org/W4405181268","https://openalex.org/W4405745481","https://openalex.org/W4410010714","https://openalex.org/W4415440825"],"related_works":["https://openalex.org/W7160099985","https://openalex.org/W3099348830","https://openalex.org/W7161126463","https://openalex.org/W2750718517","https://openalex.org/W7213323214","https://openalex.org/W7224857418","https://openalex.org/W4313262445","https://openalex.org/W2783154851","https://openalex.org/W7215854835","https://openalex.org/W3094313667"],"abstract_inverted_index":{"Hashimoto\u2019s":[0],"thyroiditis":[1],"(HT)":[2],"is":[3],"one":[4],"of":[5,80,129,170],"the":[6,13,21,31,109,176],"most":[7],"prevalent":[8],"autoimmune":[9,192],"disorders":[10],"worldwide,":[11],"yet":[12],"environmental":[14],"triggers":[15],"driving":[16],"its":[17],"progression,":[18],"especially":[19],"in":[20,34,64,100,133,191],"euthyroid":[22,36],"state,":[23],"remain":[24],"largely":[25],"elusive.":[26],"This":[27],"cross-sectional":[28],"study":[29],"investigates":[30],"gut\u2013thyroid":[32],"axis":[33],"20":[35,40],"HT":[37,53,153],"patients":[38,54,154],"and":[39,49,67,91,136,149,160,187],"matched":[41],"healthy":[42],"controls":[43],"using":[44,124],"16S":[45],"rRNA":[46],"gene":[47],"ribotyping":[48],"PICRUSt2":[50,125],"functional":[51,162],"profiling.":[52],"exhibited":[55],"significant":[56,96],"intestinal":[57],"dysbiosis,":[58],"characterized":[59],"by":[60],"a":[61,68,95],"marked":[62],"reduction":[63],"microbial":[65,158,166],"diversity":[66],"distinct":[69,156],"community":[70],"structure":[71],"relative":[72],"to":[73],"controls.":[74],"Taxonomic":[75],"analysis":[76],"revealed":[77],"an":[78,127],"expansion":[79],"potentially":[81],"pathogenic":[82],"taxa,":[83],"including":[84,139],"Staphylococcus":[85,143],"aureus,":[86],"Lawsonella":[87],"clevelandensis,":[88],"Prevotella":[89],"VZCB":[90],"Acinetobacter":[92],"plantarum.":[93],"Conversely,":[94],"depletion":[97],"was":[98],"observed":[99],"key":[101],"short-chain":[102],"fatty":[103],"acid":[104],"(SCFA)-producing":[105],"bacteria,":[106],"specifically":[107],"within":[108],"Faecalibacterium":[110],"genus":[111],"(Faecalibacterium":[112],"PRLD,":[113],"F.":[114,116,118,120],"duncaniae,":[115],"prausnitzii,":[117],"hattorii,":[119],"longum).":[121],"Functional":[122],"inference":[123],"suggested":[126],"enrichment":[128],"predicted":[130],"pathways":[131],"involved":[132],"bacterial":[134],"virulence":[135],"antimicrobial":[137],"resistance,":[138],"those":[140],"associated":[141],"with":[142],"aureus":[144],"infection,":[145],"staphylococcal":[146],"enterotoxin":[147],"production,":[148],"\u03b2-lactam":[150],"resistance.":[151],"Euthyroid":[152],"displayed":[155],"gut":[157,177],"alterations":[159],"pro-inflammatory":[161],"profiles,":[163],"suggesting":[164],"that":[165],"dysbiosis":[167],"occurs":[168],"independently":[169],"overt":[171],"thyroid":[172,193],"hormone":[173],"dysfunction.":[174],"Targeting":[175],"microbiome":[178],"may":[179],"offer":[180],"novel":[181],"avenues":[182],"for":[183],"diagnosis,":[184],"risk":[185],"stratification,":[186],"targeted":[188],"therapeutic":[189],"interventions":[190],"diseases.":[194]},"counts_by_year":[],"updated_date":"2026-11-01T11:40:01.658920","created_date":"2026-10-31T00:00:00"}