{"id":"https://openalex.org/W7224750754","doi":"https://doi.org/10.20517/jeea.2026.47","title":"Urinary polycyclic aromatic hydrocarbons and depressive/anxiety symptoms in older adults: an exploratory machine learning analysis","display_name":"Urinary polycyclic aromatic hydrocarbons and depressive/anxiety symptoms in older adults: an exploratory machine learning analysis","publication_year":2026,"publication_date":"2026-10-30","ids":{"openalex":"https://openalex.org/W7224750754","doi":"https://doi.org/10.20517/jeea.2026.47"},"language":"en","primary_location":{"id":"doi:10.20517/jeea.2026.47","doi":"https://doi.org/10.20517/jeea.2026.47","is_oa":true,"landing_page_url":"https://doi.org/10.20517/jeea.2026.47","pdf_url":"https://f.oaes.cc/xmlpdf/published/article/2607a5f95756e9a7bcb4ba70d9701884/jeea5047.pdf","source":{"id":"https://openalex.org/S4220650960","display_name":"Journal of Environmental Exposure Assessment","issn_l":"2771-5949","issn":["2771-5949"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Environmental Exposure Assessment","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://f.oaes.cc/xmlpdf/published/article/2607a5f95756e9a7bcb4ba70d9701884/jeea5047.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5160206862","display_name":"Junqi Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I160354086","display_name":"Guangxi Medical University","ror":"https://ror.org/03dveyr97","country_code":"CN","type":"education","lineage":["https://openalex.org/I160354086"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Junqi Liu","raw_affiliation_strings":["Department of Sanitary Chemistry , School of Public Health , Guangxi Medical University , Nanning 530021 , Guangxi , China","Guangxi Key Laboratory of Environment and Health Research , Guangxi Medical University , Nanning 530021 , Guangxi , China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Sanitary Chemistry , School of Public Health , Guangxi Medical University , Nanning 530021 , Guangxi , China","institution_ids":["https://openalex.org/I160354086"]},{"raw_affiliation_string":"Guangxi Key Laboratory of Environment and Health Research , Guangxi Medical University , Nanning 530021 , Guangxi , China","institution_ids":["https://openalex.org/I160354086"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160150637","display_name":"Yafei Gao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205237279","display_name":"Nankai University","ror":"https://ror.org/01y1kjr75","country_code":"CN","type":"education","lineage":["https://openalex.org/I205237279"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yafei Gao","raw_affiliation_strings":["Ministry of Education Key Laboratory of Pollution Processes and Environmental Criteria , College of Environmental Science and Engineering , Nankai University , Tianjin 300350 , China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ministry of Education Key Laboratory of Pollution Processes and Environmental Criteria , College of Environmental Science and Engineering , Nankai University , Tianjin 300350 , China","institution_ids":["https://openalex.org/I205237279"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160161678","display_name":"Jiemei Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I160354086","display_name":"Guangxi Medical University","ror":"https://ror.org/03dveyr97","country_code":"CN","type":"education","lineage":["https://openalex.org/I160354086"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiemei Li","raw_affiliation_strings":["Department of Sanitary Chemistry , School of Public Health , Guangxi Medical University , Nanning 530021 , Guangxi , China","Guangxi Key Laboratory of Environment and Health Research , Guangxi Medical University , Nanning 530021 , Guangxi , China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Sanitary Chemistry , School of Public Health , Guangxi Medical University , Nanning 530021 , Guangxi , China","institution_ids":["https://openalex.org/I160354086"]},{"raw_affiliation_string":"Guangxi Key Laboratory of Environment and Health Research , Guangxi Medical University , Nanning 530021 , Guangxi , China","institution_ids":["https://openalex.org/I160354086"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5146948972","display_name":"Biwen Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I160354086","display_name":"Guangxi Medical University","ror":"https://ror.org/03dveyr97","country_code":"CN","type":"education","lineage":["https://openalex.org/I160354086"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Biwen Wang","raw_affiliation_strings":["Department of Sanitary Chemistry , School of Public Health , Guangxi Medical University , Nanning 530021 , Guangxi , China","Guangxi Key Laboratory of Environment and Health Research , Guangxi Medical University , Nanning 530021 , Guangxi , China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Sanitary Chemistry , School of Public Health , Guangxi Medical University , Nanning 530021 , Guangxi , China","institution_ids":["https://openalex.org/I160354086"]},{"raw_affiliation_string":"Guangxi Key Laboratory of Environment and Health Research , Guangxi Medical University , Nanning 530021 , Guangxi , China","institution_ids":["https://openalex.org/I160354086"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5119074084","display_name":"Zhuoqi Zhu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I160354086","display_name":"Guangxi Medical University","ror":"https://ror.org/03dveyr97","country_code":"CN","type":"education","lineage":["https://openalex.org/I160354086"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhuoqi Zhu","raw_affiliation_strings":["Department of Sanitary Chemistry , School of Public Health , Guangxi Medical University , Nanning 530021 , Guangxi , China","Guangxi Key Laboratory of Environment and Health Research , Guangxi Medical University , Nanning 530021 , Guangxi , China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Sanitary Chemistry , School of Public Health , Guangxi Medical University , Nanning 530021 , Guangxi , China","institution_ids":["https://openalex.org/I160354086"]},{"raw_affiliation_string":"Guangxi Key Laboratory of Environment and Health Research , Guangxi Medical University , Nanning 530021 , Guangxi , China","institution_ids":["https://openalex.org/I160354086"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5160232411","display_name":"Yang Peng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I160354086","display_name":"Guangxi Medical University","ror":"https://ror.org/03dveyr97","country_code":"CN","type":"education","lineage":["https://openalex.org/I160354086"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yang Peng","raw_affiliation_strings":["Department of Environmental and Occupational Health , School of Public Health , Guangxi Medical University , Nanning 530021 , Guangxi , China","Key Laboratory of Longevity and Aging-related Diseases of the Chinese Ministry of Education , Guangxi Medical University , Nanning 530021 , Guangxi , China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Environmental and Occupational Health , School of Public Health , Guangxi Medical University , Nanning 530021 , Guangxi , China","institution_ids":["https://openalex.org/I160354086"]},{"raw_affiliation_string":"Key Laboratory of Longevity and Aging-related Diseases of the Chinese Ministry of Education , Guangxi Medical University , Nanning 530021 , Guangxi , China","institution_ids":["https://openalex.org/I160354086"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101811776","display_name":"Lu Cheng","orcid":"https://orcid.org/0000-0001-7328-8832","observed_orcids":["https://orcid.org/0000-0001-7328-8832"]},"institutions":[{"id":"https://openalex.org/I4210164269","display_name":"Shenzhen Nanshan Center for Chronic Disease Control","ror":"https://ror.org/05h3xe829","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210164269"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lu Cheng","raw_affiliation_strings":["Department of Public Health , Shenzhen Nanshan Center for Chronic Disease Control , Shenzhen 518064 , Guangdong , China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Public Health , Shenzhen Nanshan Center for Chronic Disease Control , Shenzhen 518064 , Guangdong , China","institution_ids":["https://openalex.org/I4210164269"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5118128044","display_name":"Huaicai Zeng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I176134282","display_name":"Guilin Medical University","ror":"https://ror.org/000prga03","country_code":"CN","type":"education","lineage":["https://openalex.org/I176134282"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Huaicai Zeng","raw_affiliation_strings":["Guangxi Key Laboratory of Environmental Exposomics and Entire Lifecycle Health , Guilin Medical University , Guilin 541199 , Guangxi , China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Guangxi Key Laboratory of Environmental Exposomics and Entire Lifecycle Health , Guilin Medical University , Guilin 541199 , Guangxi , China","institution_ids":["https://openalex.org/I176134282"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5148744591","display_name":"Hongzhi Zhao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205237279","display_name":"Nankai University","ror":"https://ror.org/01y1kjr75","country_code":"CN","type":"education","lineage":["https://openalex.org/I205237279"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hongzhi Zhao","raw_affiliation_strings":["Guangdong-Hong Kong-Macao Greater Bay Area Environmental Technology Research Center , Shenzhen Research Institute of Nankai University , Shenzhen 518063 , Guangdong , China","Ministry of Education Key Laboratory of Pollution Processes and Environmental Criteria , College of Environmental Science and Engineering , Nankai University , Tianjin 300350 , China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Guangdong-Hong Kong-Macao Greater Bay Area Environmental Technology Research Center , Shenzhen Research Institute of Nankai University , Shenzhen 518063 , Guangdong , China","institution_ids":["https://openalex.org/I205237279"]},{"raw_affiliation_string":"Ministry of Education Key Laboratory of Pollution Processes and Environmental Criteria , College of Environmental Science and Engineering , Nankai University , Tianjin 300350 , China","institution_ids":["https://openalex.org/I205237279"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5102801964","display_name":"Han Li","orcid":"https://orcid.org/0000-0002-3599-7950","observed_orcids":["https://orcid.org/0000-0002-3599-7950"]},"institutions":[{"id":"https://openalex.org/I160354086","display_name":"Guangxi Medical University","ror":"https://ror.org/03dveyr97","country_code":"CN","type":"education","lineage":["https://openalex.org/I160354086"]},{"id":"https://openalex.org/I205237279","display_name":"Nankai University","ror":"https://ror.org/01y1kjr75","country_code":"CN","type":"education","lineage":["https://openalex.org/I205237279"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Han Li","raw_affiliation_strings":["Correspondence to: Prof. Han Li, Department of Sanitary Chemistry, School of Public Health, Guangxi Medical University, Nanning 530021, Guangxi, China. E-mail: leehan1988@126.com; Prof. Hongzhi Zhao, Ministry of Education Key Laboratory of Pollution Processes and Environmental Criteria, College of Environmental Science and Engineering, Nankai University, Tianjin 300350, China. E-mail: hongzhizhao@nankai.edu.cn"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Correspondence to: Prof. Han Li, Department of Sanitary Chemistry, School of Public Health, Guangxi Medical University, Nanning 530021, Guangxi, China. E-mail: leehan1988@126.com; Prof. Hongzhi Zhao, Ministry of Education Key Laboratory of Pollution Processes and Environmental Criteria, College of Environmental Science and Engineering, Nankai University, Tianjin 300350, China. E-mail: hongzhizhao@nankai.edu.cn","institution_ids":["https://openalex.org/I160354086","https://openalex.org/I205237279"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.78558807,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"5","issue":"4","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10122","display_name":"Toxic Organic Pollutants Impact","score":0.9907000064849854,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10122","display_name":"Toxic Organic Pollutants Impact","score":0.9907000064849854,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T14393","display_name":"Health, Environment, Cognitive Aging","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10686","display_name":"Effects and risks of endocrine disrupting chemicals","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/polycyclic-aromatic-hydrocarbons","display_name":"polycyclic aromatic hydrocarbons","score":0.9869999885559082},{"id":"https://openalex.org/keywords/urinary-pah-metabolites","display_name":"urinary PAH metabolites","score":0.8820000290870667},{"id":"https://openalex.org/keywords/depressive-symptoms","display_name":"depressive symptoms","score":0.6840000152587891},{"id":"https://openalex.org/keywords/anxiety-symptoms","display_name":"anxiety symptoms","score":0.9990000128746033},{"id":"https://openalex.org/keywords/older-adults","display_name":"older adults","score":0.9929999709129333},{"id":"https://openalex.org/keywords/1-hydroxypyrene","display_name":"1-hydroxypyrene","score":0.9700000286102295},{"id":"https://openalex.org/keywords/body-mass-index","display_name":"body mass index","score":0.7099999785423279},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.9800000190734863},{"id":"https://openalex.org/keywords/effect-modification","display_name":"effect modification","score":0.7620000243186951},{"id":"https://openalex.org/keywords/mood-disorders","display_name":"mood disorders","score":0.46700000762939453},{"id":"https://openalex.org/keywords/shenzhen","display_name":"Shenzhen","score":0.7950000166893005}],"concepts":[{"id":"https://openalex.org/C558461103","wikidata":"https://www.wikidata.org/wiki/Q154430","display_name":"Anxiety","level":2,"score":0.6384000182151794},{"id":"https://openalex.org/C151956035","wikidata":"https://www.wikidata.org/wiki/Q1132755","display_name":"Logistic regression","level":2,"score":0.6248999834060669},{"id":"https://openalex.org/C156957248","wikidata":"https://www.wikidata.org/wiki/Q1862216","display_name":"Odds ratio","level":2,"score":0.41990000009536743},{"id":"https://openalex.org/C2776867660","wikidata":"https://www.wikidata.org/wiki/Q1814941","display_name":"Depression (economics)","level":2,"score":0.4106000065803528},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.40070000290870667},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.36809998750686646},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.3662000000476837},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.36570000648498535},{"id":"https://openalex.org/C143095724","wikidata":"https://www.wikidata.org/wiki/Q515895","display_name":"Odds","level":3,"score":0.36410000920295715},{"id":"https://openalex.org/C2778739829","wikidata":"https://www.wikidata.org/wiki/Q17027611","display_name":"Hospital Anxiety and Depression Scale","level":3,"score":0.3619000017642975},{"id":"https://openalex.org/C2776760841","wikidata":"https://www.wikidata.org/wiki/Q5550831","display_name":"Geriatric Depression Scale","level":4,"score":0.35679998993873596},{"id":"https://openalex.org/C2776317618","wikidata":"https://www.wikidata.org/wiki/Q544006","display_name":"Anxiety disorder","level":3,"score":0.3140000104904175},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.30730000138282776},{"id":"https://openalex.org/C83546350","wikidata":"https://www.wikidata.org/wiki/Q1139051","display_name":"Regression","level":2,"score":0.28610000014305115},{"id":"https://openalex.org/C48921125","wikidata":"https://www.wikidata.org/wiki/Q10861030","display_name":"Linear regression","level":2,"score":0.2842000126838684},{"id":"https://openalex.org/C152877465","wikidata":"https://www.wikidata.org/wiki/Q208042","display_name":"Regression analysis","level":2,"score":0.2768000066280365},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.27559998631477356},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.26260000467300415},{"id":"https://openalex.org/C2779159551","wikidata":"https://www.wikidata.org/wiki/Q1414874","display_name":"Comorbidity","level":2,"score":0.25529998540878296}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.20517/jeea.2026.47","doi":"https://doi.org/10.20517/jeea.2026.47","is_oa":true,"landing_page_url":"https://doi.org/10.20517/jeea.2026.47","pdf_url":"https://f.oaes.cc/xmlpdf/published/article/2607a5f95756e9a7bcb4ba70d9701884/jeea5047.pdf","source":{"id":"https://openalex.org/S4220650960","display_name":"Journal of Environmental Exposure Assessment","issn_l":"2771-5949","issn":["2771-5949"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Environmental Exposure Assessment","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.20517/jeea.2026.47","doi":"https://doi.org/10.20517/jeea.2026.47","is_oa":true,"landing_page_url":"https://doi.org/10.20517/jeea.2026.47","pdf_url":"https://f.oaes.cc/xmlpdf/published/article/2607a5f95756e9a7bcb4ba70d9701884/jeea5047.pdf","source":{"id":"https://openalex.org/S4220650960","display_name":"Journal of Environmental Exposure Assessment","issn_l":"2771-5949","issn":["2771-5949"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Environmental Exposure Assessment","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G406566814","display_name":null,"funder_award_id":"42267066","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7224750754.pdf","grobid_xml":"https://content.openalex.org/works/W7224750754.grobid-xml"},"referenced_works_count":80,"referenced_works":["https://openalex.org/W1186937996","https://openalex.org/W1958097509","https://openalex.org/W1972980696","https://openalex.org/W1981133881","https://openalex.org/W1988418417","https://openalex.org/W1988689671","https://openalex.org/W1997552208","https://openalex.org/W1999575328","https://openalex.org/W2021882121","https://openalex.org/W2028681148","https://openalex.org/W2036558184","https://openalex.org/W2050639240","https://openalex.org/W2067564773","https://openalex.org/W2068993609","https://openalex.org/W2112519660","https://openalex.org/W2149033272","https://openalex.org/W2155214743","https://openalex.org/W2160070901","https://openalex.org/W2172528686","https://openalex.org/W2201735116","https://openalex.org/W2217938672","https://openalex.org/W2265773718","https://openalex.org/W2302425592","https://openalex.org/W2415080161","https://openalex.org/W2734214472","https://openalex.org/W2738082385","https://openalex.org/W2744470738","https://openalex.org/W2766569434","https://openalex.org/W2771223908","https://openalex.org/W2771558558","https://openalex.org/W2916226351","https://openalex.org/W2932177163","https://openalex.org/W2945658293","https://openalex.org/W2947170763","https://openalex.org/W2947992151","https://openalex.org/W2961933080","https://openalex.org/W2982867873","https://openalex.org/W2990112530","https://openalex.org/W2995547960","https://openalex.org/W2998181824","https://openalex.org/W3012576217","https://openalex.org/W3026412632","https://openalex.org/W3036454441","https://openalex.org/W3042092261","https://openalex.org/W3048755037","https://openalex.org/W3081238115","https://openalex.org/W3170446616","https://openalex.org/W3188738589","https://openalex.org/W3196404960","https://openalex.org/W3196975890","https://openalex.org/W3203634758","https://openalex.org/W3206795467","https://openalex.org/W3212561452","https://openalex.org/W4224238540","https://openalex.org/W4318754617","https://openalex.org/W4321503610","https://openalex.org/W4324319952","https://openalex.org/W4385068527","https://openalex.org/W4385415958","https://openalex.org/W4385655371","https://openalex.org/W4388894257","https://openalex.org/W4391517755","https://openalex.org/W4395664415","https://openalex.org/W4400281156","https://openalex.org/W4401449535","https://openalex.org/W4402448686","https://openalex.org/W4402504492","https://openalex.org/W4402647576","https://openalex.org/W4403469328","https://openalex.org/W4406089045","https://openalex.org/W4407034401","https://openalex.org/W4409133763","https://openalex.org/W4412403637","https://openalex.org/W4415227484","https://openalex.org/W4415713305","https://openalex.org/W4415773263","https://openalex.org/W7116677955","https://openalex.org/W7125502513","https://openalex.org/W7148894662","https://openalex.org/W7164563332"],"related_works":["https://openalex.org/W4412403637","https://openalex.org/W3170446616","https://openalex.org/W4210783196","https://openalex.org/W3203634758","https://openalex.org/W4401403918","https://openalex.org/W4387652022","https://openalex.org/W7154733717","https://openalex.org/W4409133763","https://openalex.org/W4406934438","https://openalex.org/W7036262591"],"abstract_inverted_index":{"Polycyclic":[0],"aromatic":[1,70],"hydrocarbons":[2],"(PAHs)":[3],"are":[4],"ubiquitous":[5],"neurotoxic":[6],"pollutants,":[7],"yet":[8],"evidence":[9],"linking":[10],"PAHs":[11],"to":[12,74,106,112,192,236],"older":[13,228],"adults\u2019":[14],"depressive/anxiety":[15],"symptoms":[16,109,115,155],"remains":[17],"scarce.":[18],"We":[19],"explored":[20,66],"single/mixed":[21],"urinary":[22,83],"PAH-metabolite":[23],"associations":[24,121,203,226],"as":[25,27,172,218],"well":[26],"sex-":[28],"and":[29,52,62,86,110,118,188,239],"body-mass":[30],"index":[31],"(BMI)-related":[32],"effect":[33],"modification":[34],"among":[35],"413":[36],"Shenzhen":[37],"adults":[38,229],"aged":[39],"\u2265":[40],"60":[41],"years.":[42],"Symptoms":[43],"were":[44,92,122,190],"assessed":[45],"using":[46],"the":[47,173,213,231],"Geriatric":[48],"Depression":[49],"Scale":[50,55],"(GDS)":[51],"Hamilton":[53],"Anxiety":[54],"(HAMA).":[56],"Complementary":[57],"machine-learning":[58,168],"analyses":[59,102],"with":[60,94,178],"XGBoost":[61],"SHapley":[63],"Additive":[64],"exPlanations":[65],"key":[67],"hydroxylated":[68,88],"polycyclic":[69],"hydrocarbon":[71],"(OH-PAH)":[72],"metabolites":[73,90],"cross-check":[75],"conventional":[76],"regression":[77,80,128,148],"findings.":[78],"Logistic":[79],"showed":[81,163],"that":[82],"1-hydroxypyrene":[84],"(1-OHPyr)":[85],"summed":[87],"phenanthrene":[89],"(\u03a3OH-PHEs)":[91],"associated":[93],"higher":[95,150],"odds":[96,151],"of":[97,152,223],"prevalent":[98,107,113,153],"anxiety":[99,108,154,189],"symptoms.":[100,183],"Sex-stratified":[101],"linked":[103],"3-hydroxyphenanthrene":[104],"(3-OHPhe)":[105],"1-OHPyr":[111,171],"depressive":[114,182],"in":[116,124,227],"females,":[117],"stronger":[119],"1-OHPyr\u2013anxiety":[120],"observed":[123],"non-overweight":[125],"participants.":[126],"Linear":[127],"revealed":[129],"a":[130,136],"significant":[131,165,208],"1-OHPyr\u2013HAMA":[132],"association,":[133],"whereas":[134,160],"only":[135],"marginal":[137],"non-significant":[138],"trend":[139],"was":[140],"seen":[141],"for":[142,176,181,233],"GDS":[143],"scores.":[144],"Bayesian":[145],"kernel":[146],"machine":[147],"indicated":[149],"at":[156],"high":[157],"mixture":[158],"exposure,":[159],"quantile":[161],"g-computation":[162],"no":[164],"association.":[166],"The":[167],"analysis":[169],"flagged":[170],"top":[174],"predictor":[175],"anxiety,":[177],"suggestive":[179],"signals":[180],"Associations":[184],"between":[185],"phenanthrene-derived":[186],"OH-PAHs":[187],"subject":[191],"BMI":[193],"modification.":[194],"However,":[195],"after":[196],"false":[197],"discovery":[198],"rate":[199],"(FDR)":[200],"correction,":[201],"these":[202],"did":[204],"not":[205],"remain":[206],"statistically":[207],"(smallest":[209],"PFDR":[210],"=":[211],"0.494);":[212],"findings":[214,238],"should":[215],"be":[216],"regarded":[217],"hypothesis-generating.":[219],"This":[220],"simultaneous":[221],"assessment":[222],"PAH-related":[224],"mood-symptom":[225],"highlights":[230],"need":[232],"prospective":[234],"cohorts":[235],"verify":[237],"clarify":[240],"underlying":[241],"mechanisms.":[242]},"counts_by_year":[],"updated_date":"2026-11-03T10:50:19.383937","created_date":"2026-10-31T00:00:00"}